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The balance of TCF7L2 variants with differential activities in Wnt-signaling is regulated by lithium in a GSK3β-independent manner

https://doi.org/10.1016/j.bbrc.2010.07.062
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1006/scbi.2000.0342openalex-snapshot
Cellular transformation by SV40 large T antigen: interaction with host proteins
inferredcites →https://doi.org/10.1038/labinvest.3700273openalex-snapshot
Upregulation of TCF4 expression as a transcriptional target of β-catenin/p300 complexes during trans-differentiation of endometrial carcinoma cells
inferredcites →https://doi.org/10.1038/nature03319openalex-snapshot
Wnt signalling in stem cells and cancer
inferredcites →https://doi.org/10.1038/ng.530openalex-snapshot
A map of open chromatin in human pancreatic islets
inferredcites →https://doi.org/10.1038/ng1732openalex-snapshot
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
inferredcites →https://doi.org/10.1038/sj.onc.1209471openalex-snapshot
TCF-4 isoforms absent in TCF-4 mutated MSI-H colorectal cancer cells colocalize with nuclear CtBP and repress TCF-4-mediated transcription
inferredcites →https://doi.org/10.1038/sj.onc.1210056openalex-snapshot
Diversity of LEF/TCF action in development and disease
inferredcites →https://doi.org/10.1074/jbc.272.40.24735openalex-snapshot
Serine Phosphorylation-regulated Ubiquitination and Degradation of β-Catenin
inferredcites →https://doi.org/10.1074/jbc.m101188200openalex-snapshot
Lithium Inhibits Cell Cycle Progression and Induces Stabilization of p53 in Bovine Aortic Endothelial Cells
inferredcites →https://doi.org/10.1074/jbc.m109.001735openalex-snapshot
Enhanced Endothelial Cell Senescence by Lithium-induced Matrix Metalloproteinase-1 Expression
inferredcites →https://doi.org/10.1093/emboj/20.17.4912openalex-snapshot
Deregulated β‐catenin induces a p53‐ and ARF‐dependent growth arrest and cooperates with Ras in transformation
inferredcites →https://doi.org/10.1093/hmg/ddp321openalex-snapshot
Tissue-specific alternative splicing of TCF7L2
inferredcites →https://doi.org/10.1093/nar/gkp1197openalex-snapshot
Alternative splicing of Tcf7l2 transcripts generates protein variants with differential promoter-binding and transcriptional activation properties at Wnt/β-catenin targets
inferredcites →https://doi.org/10.1096/fj.04-3458fjeopenalex-snapshot
Blood‐brain barrier‐specific properties of a human adult brain endothelial cell line
inferredcites →https://doi.org/10.1111/1523-1747.ep12613748openalex-snapshot
HMEC-1: Establishment of an Immortalized Human Microvascular Endothelial Cell Line
inferredcites →https://doi.org/10.1111/j.1742-4658.2007.05809.xopenalex-snapshot
Lithium increases PGC‐1α expression and mitochondrial biogenesis in primary bovine aortic endothelial cells
inferredcites →https://doi.org/10.1126/science.1143578openalex-snapshot
Augmented Wnt Signaling in a Mammalian Model of Accelerated Aging
inferredcites →https://doi.org/10.1126/science.1144090openalex-snapshot
Increased Wnt Signaling During Aging Alters Muscle Stem Cell Fate and Increases Fibrosis
inferredcites →https://doi.org/10.1126/science.275.5307.1784openalex-snapshot
Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC −/− Colon Carcinoma
inferredcites →https://doi.org/10.1128/mcb.01360-07openalex-snapshot
β-Catenin Expression Results in p53-Independent DNA Damage and Oncogene-Induced Senescence in Prelymphomagenic Thymocytes In Vivo
inferredcites →https://doi.org/10.1128/mcb.02132-06openalex-snapshot
A Unique DNA Binding Domain Converts T-Cell Factors into Strong Wnt Effectors
inferredcites →https://doi.org/10.1158/0008-5472.can-08-1909openalex-snapshot
Epidermal Growth Factor Receptor/β-Catenin/T-Cell Factor 4/Matrix Metalloproteinase 1: A New Pathway for Regulating Keratinocyte Invasiveness after UVA Irradiation
inferredcites →https://doi.org/10.1242/jcs.00384openalex-snapshot
GSK-3: tricks of the trade for a multi-tasking kinase
inferredcites →https://doi.org/10.1371/journal.pone.0007697openalex-snapshot
TCF7L2 Polymorphism rs7903146 Is Associated with Coronary Artery Disease Severity and Mortality
inferredcites →https://doi.org/10.1371/journal.pone.0007872openalex-snapshot
Control of TCF-4 Expression by VDR and Vitamin D in the Mouse Mammary Gland and Colorectal Cancer Cell Lines
inferredcites →https://doi.org/10.2337/db06-0381openalex-snapshot
Common Single Nucleotide Polymorphisms in TCF7L2 Are Reproducibly Associated With Type 2 Diabetes and Reduce the Insulin Response to Glucose in Nondiabetic Individuals

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4797420openalex-extracted
Integrative Identification of Driver Genes for Enhanced Personalized Cancer Subtype Classification
inferred← citeshttps://doi.org/10.1002/9781118444122.ch17openalex-snapshot
Evolutionary Diversification of Vertebrate TCF/LEF Structure, Function, and Regulation
inferred← citeshttps://doi.org/10.1016/j.ajpath.2016.06.015openalex-snapshot
Pharmacologic Activation of Wnt Signaling by Lithium Normalizes Retinal Vasculature in a Murine Model of Familial Exudative Vitreoretinopathy
inferred← citeshttps://doi.org/10.1016/j.metabol.2015.10.013openalex-snapshot
Wnt signaling pathway in cardiac fibrosis: New insights and directions
inferred← citeshttps://doi.org/10.1080/13102818.2018.1438211openalex-snapshot
Possible role of TCF7L2 in the pathogenesis of type 2 diabetes mellitus
inferred← citeshttps://doi.org/10.1101/gad.17227011openalex-snapshot
A novel mechanism for the transcriptional regulation of Wnt signaling in development
inferred← citeshttps://doi.org/10.1186/1755-8794-6-s1-s17openalex-snapshot
Exploring the pathogenetic association between schizophrenia and type 2 diabetes mellitus diseases based on pathway analysis
inferred← citeshttps://doi.org/10.1371/journal.pone.0029228openalex-snapshot
Association of the Type 2 Diabetes Mellitus Susceptibility Gene, TCF7L2, with Schizophrenia in an Arab-Israeli Family Sample
inferred← citeshttps://doi.org/10.1371/journal.pone.0067694openalex-snapshot
GRG5/AES Interacts with T-Cell Factor 4 (TCF4) and Downregulates Wnt Signaling in Human Cells and Zebrafish Embryos
inferred← citeshttps://doi.org/10.1515/biol-2016-0013openalex-snapshot
Advancement of Wnt signal pathway and the target of breast cancer
inferred← citeshttps://doi.org/10.15252/emmm.202217094openalex-snapshot
Functional analysis reveals driver cooperativity and novel mechanisms in endometrial carcinogenesis
inferred← citeshttps://doi.org/10.1615/critreveukargeneexpr.v21.i3.10openalex-snapshot
Cell-Context Dependent TCF/LEF Expression and Function: Alternative Tales of Repression, De-Repression and Activation Potentials
inferred← citeshttps://doi.org/10.18632/oncotarget.15603openalex-snapshot
TCF7L2 polymorphisms and the risk of schizophrenia in the Chinese Han population
inferred← citeshttps://doi.org/10.21248/gups.87954openalex-snapshot
2-Desaza-annomontine impedes angiogenesis by inhibiting CDC2-like-kinases and β-catenin activity
inferred← citeshttps://doi.org/10.2147/dmso.s230061openalex-snapshot
Type 2 Diabetes-Associated Genetic Polymorphisms as Potential Disease Predictors
inferred← citeshttps://doi.org/10.3389/fphar.2018.00379openalex-snapshot
The Wnt Signaling Pathway Effector TCF7L2 Mediates Olanzapine-Induced Weight Gain and Insulin Resistance
inferred← citeshttps://doi.org/10.3390/ijms27198655openalex-snapshot
Intra-Abdominal Sporadic Desmoid Tumors with Canonical CTNNB1 and Uncommon Wnt/β-Catenin Pathway Somatic Mutations—A Clinicopathologic and Genetic Study of Five Cases
inferred← citeshttps://doi.org/10.3410/f.13277019.14635134openalex-snapshot
Faculty Opinions recommendation of A novel mechanism for the transcriptional regulation of Wnt signaling in development.
inferred← citeshttps://doi.org/10.7150/thno.35882openalex-snapshot
HIF-1α/Wnt signaling-dependent control of gene transcription regulates neuronal differentiation of glioblastoma stem cells
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