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Carbon monoxide regulates glycolysis-dependent NLRP3 inflammasome activation in macrophages

https://doi.org/10.1016/j.bbrc.2017.09.111

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2 of the 42 references listed on this page are in the Retraction Watch database as retracted (export 2026-11-04): 10.1016/j.celrep.2015.05.046 (notice 2023-06-06), 10.1165/rcmb.4851 (notice 2023-07-01).

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/eji.201242684openalex-snapshot

Carbon monoxide‐treated dendritic cells decrease β1‐integrin induction on CD8+ T cells and protect from type 1 diabetes

inferredcites →https://doi.org/10.1016/j.cell.2012.03.017openalex-snapshot

mTOR Signaling in Growth Control and Disease

inferredcites →https://doi.org/10.1016/j.cell.2014.02.008openalex-snapshot

Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes

inferredcites →https://doi.org/10.1016/j.celrep.2015.05.046openalex-snapshot

RETRACTED: mTORC1-Induced HK1-Dependent Glycolysis Regulates NLRP3 Inflammasome Activation

inferredcites →https://doi.org/10.1016/j.cmet.2007.10.002openalex-snapshot

The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

inferredcites →https://doi.org/10.1016/j.cmet.2013.05.001openalex-snapshot

Inflammation in Obesity and Diabetes: Islet Dysfunction and Therapeutic Opportunity

inferredcites →https://doi.org/10.1016/j.immuni.2006.02.004openalex-snapshot

Critical Role for NALP3/CIAS1/Cryopyrin in Innate and Adaptive Immunity through Its Regulation of Caspase-1

inferredcites →https://doi.org/10.1016/j.immuni.2006.03.012openalex-snapshot

Carbon Monoxide Orchestrates a Protective Response through PPARγ

inferredcites →https://doi.org/10.1016/j.molcel.2010.06.022openalex-snapshot

Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1

inferredcites →https://doi.org/10.1016/s0002-9440(10)62229-8openalex-snapshot

Carbon Monoxide Suppresses Bleomycin-Induced Lung Fibrosis

inferredcites →https://doi.org/10.1016/s0021-9258(18)31720-4openalex-snapshot

Glucose is essential for proliferation and the glycolytic enzyme induction that provokes a transition to glycolytic energy production.

inferredcites →https://doi.org/10.1016/s0092-8674(02)00808-5openalex-snapshot

mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth Machinery

inferredcites →https://doi.org/10.1023/a:1015957026924openalex-snapshot

Heme oxygenase/carbon monoxide signaling pathways: Regulation and functional significance

inferredcites →https://doi.org/10.1038/nature05485openalex-snapshot

Inflammation and metabolic disorders

inferredcites →https://doi.org/10.1038/ni.1703openalex-snapshot

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

inferredcites →https://doi.org/10.1038/ni.1831openalex-snapshot

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

inferredcites →https://doi.org/10.1038/ni.2833openalex-snapshot

TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation

inferredcites →https://doi.org/10.1038/nm.2279openalex-snapshot

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

inferredcites →https://doi.org/10.1038/nm.4188openalex-snapshot

Dual effects of carbon monoxide on pericytes and neurogenesis in traumatic brain injury

inferredcites →https://doi.org/10.1038/nrd3228openalex-snapshot

The therapeutic potential of carbon monoxide

inferredcites →https://doi.org/10.1038/nrd4275openalex-snapshot

Targeting inflammation in the treatment of type 2 diabetes: time to start

inferredcites →https://doi.org/10.1038/nri1710openalex-snapshot

Fuel feeds function: energy metabolism and the T-cell response

inferredcites →https://doi.org/10.1038/nri2725openalex-snapshot

NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production?

inferredcites →https://doi.org/10.1038/nri3230openalex-snapshot

Stabilizing immune regulation in the gut

inferredcites →https://doi.org/10.1038/nri3452openalex-snapshot

Activation and regulation of the inflammasomes

inferredcites →https://doi.org/10.1038/nrm2672openalex-snapshot

Molecular mechanisms of mTOR-mediated translational control

inferredcites →https://doi.org/10.1038/sj.cdd.4401734openalex-snapshot

Cryopyrin and pyrin activate caspase-1, but not NF-κB, via ASC oligomerization

inferredcites →https://doi.org/10.1074/jbc.m302942200openalex-snapshot

Suppression of Inflammatory Cytokine Production by Carbon Monoxide Involves the JNK Pathway and AP-1

inferredcites →https://doi.org/10.1074/jbc.m411863200openalex-snapshot

The Hyperglycemia-induced Inflammatory Response in Adipocytes

inferredcites →https://doi.org/10.1084/jem.20110278openalex-snapshot

HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells

inferredcites →https://doi.org/10.1089/ars.2007.1762openalex-snapshot

Carbon Monoxide in Sepsis

inferredcites →https://doi.org/10.1126/science.7678352openalex-snapshot

Carbon Monoxide: a Putative Neural Messenger

inferredcites →https://doi.org/10.1126/stke.2302004re6openalex-snapshot

Carbon Monoxide: To Boldly Go Where NO Has Gone Before

inferredcites →https://doi.org/10.1152/ajplung.1999.276.4.l688openalex-snapshot

Carbon monoxide provides protection against hyperoxic lung injury

inferredcites →https://doi.org/10.1152/physrev.00011.2005openalex-snapshot

Heme Oxygenase-1/Carbon Monoxide: From Basic Science to Therapeutic Applications

inferredcites →https://doi.org/10.1164/rccm.200401-023ocopenalex-snapshot

Inhaled Carbon Monoxide Confers Antiinflammatory Effects against Ventilator-induced Lung Injury

inferredcites →https://doi.org/10.1165/rcmb.4851openalex-snapshot

Carbon Monoxide Inhibits Human Airway Smooth Muscle Cell Proliferation via Mitogen-Activated Protein Kinase Pathway

inferredcites →https://doi.org/10.2337/dc16-0989openalex-snapshot

Management of Inpatient Hyperglycemia and Diabetes in Older Adults

inferredcites →https://doi.org/10.2337/diabetes.51.4.994openalex-snapshot

Carbon Monoxide Protects Pancreatic β-Cells From Apoptosis and Improves Islet Function/Survival After Transplantation

inferredcites →https://doi.org/10.2337/diabetes.54.5.1400openalex-snapshot

Donor Treatment With Carbon Monoxide Can Yield Islet Allograft Survival and Tolerance

inferredcites →https://doi.org/10.4049/jimmunol.1003613openalex-snapshot

Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets

inferredcites →https://doi.org/10.4049/jimmunol.180.7.4476openalex-snapshot

Glucose Uptake Is Limiting in T Cell Activation and Requires CD28-Mediated Akt-Dependent and Independent Pathways

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Shengxian Decoction Protects Against Obesity-Induced Cardiac Injuryin Rats by Regulating the Hk1/Nlrp3 Signalling Pathway

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Carbon Monoxide and Energy Metabolism

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Metalloimmunotherapy with Rhodium and Ruthenium Complexes: Targeting Tumor‐Associated Macrophages

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Interactions between NLRP3 inflammasome and glycolysis in macrophages: New insights into chronic inflammation pathogenesis

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Carbon Monoxide Alleviates Cardiomyocyte Pyroptosis in Diabetic Cardiomyopathy by Downregulating the IL‐33/ST2L Axis

inferred← citeshttps://doi.org/10.1007/s00204-021-02976-7openalex-snapshot

Carbon monoxide-triggered health effects: the important role of the inflammasome and its possible crosstalk with autophagy and exosomes

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CORM-3 alleviates the intestinal injury in a rodent model of hemorrhage shock and resuscitation: roles of GFAP-positive glia

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Carbon Monoxide-Neuroglobin Axis Targeting Metabolism Against Inflammation in BV-2 Microglial Cells

inferred← citeshttps://doi.org/10.1016/j.abb.2019.108186openalex-snapshot

Heme oxygenase-1/carbon monoxide as modulators of autophagy and inflammation

inferred← citeshttps://doi.org/10.1016/j.bbadis.2024.167446openalex-snapshot

Carbon monoxide and mitochondria: Cell energy and fate control

inferred← citeshttps://doi.org/10.1016/j.bbrc.2017.12.134openalex-snapshot

Hypoxia potentiates LPS-induced inflammatory response and increases cell death by promoting NLRP3 inflammasome activation in pancreatic β cells

inferred← citeshttps://doi.org/10.1016/j.bcp.2022.115058openalex-snapshot

Carbon monoxide (CO)/heme oxygenase (HO)-1 in gastrointestinal tumors pathophysiology and pharmacology - possible anti- and pro-cancer activities

inferred← citeshttps://doi.org/10.1016/j.inoche.2020.108093openalex-snapshot

Water-soluble UV/visible light activated Mn-CO-releasing molecules: Synthesis, structure, CO releasing and biological activities evaluation

inferred← citeshttps://doi.org/10.1016/j.intimp.2018.01.023openalex-snapshot

Chrysophanol demonstrates anti-inflammatory properties in LPS-primed RAW 264.7 macrophages through activating PPAR-γ

inferred← citeshttps://doi.org/10.1016/j.intimp.2022.109072openalex-snapshot

Inflammasome Complexes: Crucial mediators in osteoimmunology and bone diseases

inferred← citeshttps://doi.org/10.1016/j.jhazmat.2025.139135openalex-snapshot

A turn-on near-infrared fluorescent probe for monitoring carbon monoxide in bacterial pneumonia and cadmium ion induced abiotic stress responses in plants

inferred← citeshttps://doi.org/10.1016/j.neuint.2026.106205openalex-snapshot

Heme oxygenase/carbon monoxide in thermoregulation and neuroenergetics

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Metal Drugs and the Anticancer Immune Response

inferred← citeshttps://doi.org/10.1080/00958972.2023.2165070openalex-snapshot

Synthesis, structure, CO releasing, and biological activities of new 1-D chain Mn(I)/Mn(II) visible light activated CO-releasing molecules (CORMs)

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Carbon Monoxide Attenuates Lipopolysaccharides (LPS)-Induced Acute Lung Injury in Neonatal Rats via Downregulation of Cx43 to Reduce Necroptosis

inferred← citeshttps://doi.org/10.1538/expanim.22-0023openalex-snapshot

Carbon monoxide ameliorates lipopolysaccharide-induced acute lung injury via inhibition of alveolar macrophage pyroptosis

inferred← citeshttps://doi.org/10.21203/rs.3.rs-852619/v1openalex-snapshot

Carbon Monoxide-Neuroglobin Axis Targeting Metabolism Against Neuroinflammation

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Mechanisms of immunity and inflammation in Brucella-induced arthritis

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Modulation of Inflammation and Immune Responses by Heme Oxygenase-1: Implications for Infection with Intracellular Pathogens

inferred← citeshttps://doi.org/10.3390/ijms20153675openalex-snapshot

Heme, Heme Oxygenase, and Endoplasmic Reticulum Stress—A New Insight into the Pathophysiology of Vascular Diseases

inferred← citeshttps://doi.org/10.3390/ijms22010047openalex-snapshot

Therapeutic Potential of Carbon Monoxide (CO) and Hydrogen Sulfide (H2S) in Hemolytic and Hemorrhagic Vascular Disorders—Interaction between the Heme Oxygenase and H2S-Producing Systems

inferred← citeshttps://doi.org/10.3892/ijmm.2020.4493openalex-snapshot

Exogenous carbon monoxide protects against mitochondrial DNA‑induced hippocampal pyroptosis in a model of hemorrhagic shock and resuscitation

inferred← citeshttps://doi.org/10.7883/yoken.jjid.2022.647openalex-snapshot

Mycobacterium tuberculosis Rv2653 Protein Promotes Inflammation Response by Enhancing Glycolysis

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