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Nitric oxide-induced apoptosis is mediated by Bax/Bcl-2 gene expression, transition of cytochrome c, and activation of caspase-3 in rat vascular smooth muscle cells

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1006/bbrc.1996.0563openalex-snapshot
Nitric Oxide Donor SNAP Induces Apoptosis in Smooth Muscle Cells through cGMP-Independent Mechanism
inferredcites →https://doi.org/10.1006/jsre.1998.5405openalex-snapshot
Nitric Oxide Causes Apoptosis in Pulmonary Vascular Smooth Muscle Cells
inferredcites →https://doi.org/10.1007/978-1-4899-1819-2_41openalex-snapshot
A Role for Nitric Oxide and Other Inflammatory Mediators in Cytokine-Induced Pancreatic β-Cell Dysfunction and Destruction
inferredcites →https://doi.org/10.1007/s002620050310openalex-snapshot
Bcl-2 protects cells from cytokine-induced nitric-oxide-dependent apoptosis
inferredcites →https://doi.org/10.1016/0092-8674(95)90412-3openalex-snapshot
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
inferredcites →https://doi.org/10.1016/0169-4758(93)90226-6openalex-snapshot
Nitric oxide-mediated apoptosis in murine peritoneal macrophages
inferredcites →https://doi.org/10.1016/s0008-6363(98)00212-0openalex-snapshot
Apoptosis of vascular smooth muscle cells in vascular remodelling and atherosclerotic plaque rupture
inferredcites →https://doi.org/10.1016/s0014-2999(97)01368-xopenalex-snapshot
Nitric oxide donor-induced apoptosis in smooth muscle cells is modulated by protein kinase C and protein kinase A
inferredcites →https://doi.org/10.1016/s0014-2999(98)00274-xopenalex-snapshot
Nitric oxide and its role in apoptosis
inferredcites →https://doi.org/10.1016/s0024-3205(97)01092-8openalex-snapshot
NO INDUCED APOPTOSIS ACCOMPANYING THE CHANGE OF ONCOPROTEIN EXPRESSION AND THE ACTIVATION OF CPP32 PROTEASE
inferredcites →https://doi.org/10.1016/s0076-6879(96)69017-xopenalex-snapshot
[14] Cyclic GMP-dependent protein kinase in nitric oxide signaling
inferredcites →https://doi.org/10.1016/s0092-8674(00)80085-9openalex-snapshot
Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c
inferredcites →https://doi.org/10.1016/s0167-4889(97)00093-1openalex-snapshot
Reduced glutathione prevents nitric oxide-induced apoptosis in vascular smooth muscle cells
inferredcites →https://doi.org/10.1016/s1357-2725(98)00071-5openalex-snapshot
Role of nitric oxide in the control of apoptosis in the microvasculature
inferredcites →https://doi.org/10.1038/380723a0openalex-snapshot
Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis
inferredcites →https://doi.org/10.1038/sj.cdd.4400439openalex-snapshot
Growth factors prevent changes in Bcl-2 and Bax expression and neuronal apoptosis induced by nitric oxide
inferredcites →https://doi.org/10.1046/j.1471-4159.1998.71010088.xopenalex-snapshot
Induction of Nitric Oxide Synthase and Nitric Oxide‐Mediated Apoptosis in Neuronal PC12 Cells After Stimulation with Tumor Necrosis FActor‐α/Lipopolysaccharide
inferredcites →https://doi.org/10.1074/jbc.272.2.1402openalex-snapshot
Nitric Oxide Protects Cultured Rat Hepatocytes from Tumor Necrosis Factor-α-induced Apoptosis by Inducing Heat Shock Protein 70 Expression
inferredcites →https://doi.org/10.1074/jbc.273.51.34263openalex-snapshot
Adenovirus-mediated Gene Transfer of cGMP-dependent Protein Kinase Increases the Sensitivity of Cultured Vascular Smooth Muscle Cells to the Antiproliferative and Pro-apoptotic Effects of Nitric Oxide/cGMP
inferredcites →https://doi.org/10.1074/jbc.274.21.15237openalex-snapshot
p53 Suppresses the Activation of the Bcl-2 Promoter by the Brn-3a POU Family Transcription Factor
inferredcites →https://doi.org/10.1084/jem.185.4.601openalex-snapshot
Suppression of Apoptosis by Nitric Oxide via Inhibition of Interleukin-1β–converting Enzyme (ICE)-like and Cysteine Protease Protein (CPP)-32–like Proteases
inferredcites →https://doi.org/10.1084/jem.187.3.415openalex-snapshot
Disruption of Fas Receptor Signaling by Nitric Oxide in Eosinophils
inferredcites →https://doi.org/10.1126/science.275.5303.1132openalex-snapshot
The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis
inferredcites →https://doi.org/10.1126/science.281.5381.1309openalex-snapshot
Mitochondria and Apoptosis
inferredcites →https://doi.org/10.1152/ajpcell.00119.2001openalex-snapshot
Potentiation of nitric oxide-induced apoptosis in p53−/− vascular smooth muscle cells
inferredcites →https://doi.org/10.1152/ajpheart.1998.274.4.h1132openalex-snapshot
Molecular characterization of rabbit CPP32 and its function in vascular smooth muscle cell apoptosis
inferredcites →https://doi.org/10.1152/ajpheart.2002.282.1.h184openalex-snapshot
Nitric oxide induces apoptosis by activating K + channels in pulmonary vascular smooth muscle cells
inferredcites →https://doi.org/10.1159/000047808openalex-snapshot
Involvement of PKC and NF-κB in Nitric Oxide Induced Apoptosis in Human Coronary Artery Smooth Muscle Cells
inferredcites →https://doi.org/10.1161/01.atv.19.1.14openalex-snapshot
Apoptosis
inferredcites →https://doi.org/10.1161/01.cir.98.12.1212openalex-snapshot
Transfection of Inducible Nitric Oxide Synthase Gene Causes Apoptosis in Vascular Smooth Muscle Cells
inferredcites →https://doi.org/10.1161/01.hyp.27.3.823openalex-snapshot
Nitric Oxide Induces Upregulation of Fas and Apoptosis in Vascular Smooth Muscle
inferredcites →https://doi.org/10.1161/01.res.79.4.748openalex-snapshot
Vasoactive Substances Regulate Vascular Smooth Muscle Cell Apoptosis
inferredcites →https://doi.org/10.1161/01.res.82.11.1111openalex-snapshot
Apoptosis
inferredcites →https://doi.org/10.1161/01.res.84.3.253openalex-snapshot
Nitric Oxide as a Bifunctional Regulator of Apoptosis
inferredcites →https://doi.org/10.1172/jci117869openalex-snapshot
Splenic B lymphocyte programmed cell death is prevented by nitric oxide release through mechanisms involving sustained Bcl-2 levels.
inferredcites →https://doi.org/10.4049/jimmunol.150.11.5080openalex-snapshot
Nitric oxide-mediated apoptosis in murine peritoneal macrophages
inferredcites →https://doi.org/10.4049/jimmunol.155.6.2858openalex-snapshot
Nitric oxide induces apoptosis in mouse thymocytes

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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inferred← citeshttps://doi.org/10.1002/bies.20324openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/jbm.a.34337openalex-snapshot
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Laminar shear stress stimulates vascular smooth muscle cell apoptosis via the Akt pathway
inferred← citeshttps://doi.org/10.1002/jnr.20739openalex-snapshot
Mitochondrial involvement in nitric oxide‐induced cellular death in cortical neurons in culture
inferred← citeshttps://doi.org/10.1002/jnr.21342openalex-snapshot
Mechanisms of nitric oxide‐induced apoptosis in bovine chromaffin cells: Role of mitochondria and apoptotic proteins
inferred← citeshttps://doi.org/10.1002/jor.25008openalex-snapshot
Intra‐articular treatment with hyaluronic acid associated with gold nanoparticles in a mechanical osteoarthritis model in Wistar rats
inferred← citeshttps://doi.org/10.1002/mc.20559openalex-snapshot
Activation of p53/p21/PUMA alliance and disruption of PI‐3/Akt in multimodal targeting of apoptotic signaling cascades in cervical cancer cells by a pentacyclic triterpenediol fromBoswellia serrata
inferred← citeshttps://doi.org/10.1002/ppul.21491openalex-snapshot
Hypoxia and nitric oxide exposure promote apoptotic signaling in contractile pulmonary arterial smooth muscle but not in pulmonary epithelium
inferred← citeshttps://doi.org/10.1007/978-1-60327-009-0_6openalex-snapshot
Gestation-Induced Uterine Vascular Remodeling
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inferred← citeshttps://doi.org/10.1007/s10495-006-6986-xopenalex-snapshot
Molecular characterization of cytotoxic and resistance mechanisms induced by NCX 4040, a novel NO-NSAID, in pancreatic cancer cell lines*
inferred← citeshttps://doi.org/10.1007/s10753-020-01291-0openalex-snapshot
Effects of Percutaneous Collagen Induction Therapy Associated with Hyaluronic Acid on Inflammatory Response, Oxidative Stress, and Collagen Production
inferred← citeshttps://doi.org/10.1007/s11055-008-0046-7openalex-snapshot
Morphological characteristics of apoptosis and its significance in neurogenesis
inferred← citeshttps://doi.org/10.1007/s12011-016-0925-7openalex-snapshot
The Effect of Selenium on the Cd-Induced Apoptosis via NO-Mediated Mitochondrial Apoptosis Pathway in Chicken Liver
inferred← citeshttps://doi.org/10.1007/s12264-020-00471-0openalex-snapshot
Aloin Protects Against Blood–Brain Barrier Damage After Traumatic Brain Injury in Mice
inferred← citeshttps://doi.org/10.1016/j.bbabio.2006.03.008openalex-snapshot
Energy deficiency in the failing heart: Linking increased reactive oxygen species and disruption of oxidative phosphorylation rate
inferred← citeshttps://doi.org/10.1016/j.cbi.2017.08.011openalex-snapshot
Colistin-induced autophagy and apoptosis involves the JNK-Bcl2-Bax signaling pathway and JNK-p53-ROS positive feedback loop in PC-12 cells
inferred← citeshttps://doi.org/10.1016/j.cca.2022.09.017openalex-snapshot
Interleukin-38 in atherosclerosis
inferred← citeshttps://doi.org/10.1016/j.dci.2016.02.017openalex-snapshot
Molecular cloning, characterization and expression analysis of (B-cell lymphoma-2 associated X protein) Bax in the orange-spotted grouper (Epinephelus coioides) after the Vibrio alginolyticus challenge
inferred← citeshttps://doi.org/10.1016/j.dci.2019.103490openalex-snapshot
Bax functions as coelomocyte apoptosis regulator in the sea cucumber Apostichopus japonicus
inferred← citeshttps://doi.org/10.1016/j.ejphar.2011.06.020openalex-snapshot
Luteolin improves contractile function and attenuates apoptosis following ischemia–reperfusion in adult rat cardiomyocytes
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2010.08.030openalex-snapshot
Differential susceptibility to nitric oxide-evoked apoptosis in human inflammatory cells
inferred← citeshttps://doi.org/10.1016/j.fsi.2021.11.014openalex-snapshot
Albicanol inhibits the toxicity of profenofos to grass carp hepatocytes cells through the ROS/PTEN/PI3K/AKT axis
inferred← citeshttps://doi.org/10.1016/j.intimp.2014.03.018openalex-snapshot
Anti-oxidant and anti-apoptotic effects of luteolin on mice peritoneal macrophages stimulated by angiotensin II
inferred← citeshttps://doi.org/10.1016/j.jconrel.2026.114604openalex-snapshot
Nanostrategies for potentiating gas-immunotherapy: From advanced delivery platforms to anti-tumor applications
inferred← citeshttps://doi.org/10.1016/j.jss.2006.11.026openalex-snapshot
Hypertension Induces Compensatory Arterial Remodeling Following Arteriotomy
inferred← citeshttps://doi.org/10.1016/j.msec.2020.110681openalex-snapshot
Effects of phonophoresis with diclofenac linked gold nanoparticles in model of traumatic muscle injury
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2018.02.017openalex-snapshot
Nitric Oxide and Mitochondrial Function in Neurological Diseases
inferred← citeshttps://doi.org/10.1016/j.niox.2009.12.003openalex-snapshot
Influence of cholesterol and fish oil dietary intake on nitric oxide-induced apoptosis in vascular smooth muscle cells
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2004.11.006openalex-snapshot
Modulation of apoptosis by nitric oxide: implications in myocardial ischemia and heart failure
inferred← citeshttps://doi.org/10.1016/j.redox.2026.104126openalex-snapshot
Regulatory interplay between nitric oxide and heme in redox signaling and inflammation
inferred← citeshttps://doi.org/10.1016/s1665-2681(19)31436-xopenalex-snapshot
Role of nitric oxide in liver regeneration
inferred← citeshttps://doi.org/10.1021/acs.jafc.1c06516openalex-snapshot
Protein S-Nitrosylation Regulates Postmortem Beef Apoptosis through the Intrinsic Mitochondrial Pathway
inferred← citeshttps://doi.org/10.1021/acsbiomaterials.0c00294openalex-snapshot
Effects of the Association between Photobiomodulation and Hyaluronic Acid Linked Gold Nanoparticles in Wound Healing
inferred← citeshttps://doi.org/10.1038/sj.bjp.0706200openalex-snapshot
Prostacyclin prevents nitric oxide‐induced megakaryocyte apoptosis
inferred← citeshttps://doi.org/10.1039/d0fo03270kopenalex-snapshot
Albicanol antagonizes Cd-induced apoptosis through a NO/iNOS-regulated mitochondrial pathway in chicken liver cells
inferred← citeshttps://doi.org/10.1074/jbc.m109.094581openalex-snapshot
Differential Roles of Epac in Regulating Cell Death in Neuronal and Myocardial Cells
inferred← citeshttps://doi.org/10.1080/10715762.2018.1455095openalex-snapshot
Src kinase activation by nitric oxide promotes resistance to anoikis in tumour cell lines
inferred← citeshttps://doi.org/10.1093/abbs/36.8.559openalex-snapshot
Inhibiting Apoptosis of CTLL-2 Cells to Enhance their GVL Effects via Anti-Fas Ribozyme
inferred← citeshttps://doi.org/10.1093/cvr/cvw062openalex-snapshot
Augmentation of phosphate-induced osteo-/chondrogenic transformation of vascular smooth muscle cells by homoarginine
inferred← citeshttps://doi.org/10.1093/gerona/glr083openalex-snapshot
Effect of a Combined Treatment With Growth Hormone and Melatonin in the Cardiological Aging on Male SAMP8 Mice
inferred← citeshttps://doi.org/10.1093/toxsci/kfj168openalex-snapshot
Inducible Nitric Oxide Synthase and Apoptosis in Murine Proximal Tubule Epithelial Cells
inferred← citeshttps://doi.org/10.1097/01.crd.0000249381.49138.b9openalex-snapshot
Pulmonary Artery Hypertension
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Improvement of Contractile Function in Isolated Cardiomyocytes From Ischemia-Reperfusion Rats by Ginkgolide B Pretreatment
inferred← citeshttps://doi.org/10.1111/j.1600-6143.2006.01435.xopenalex-snapshot
FK330, a Novel Inducible Nitric Oxide Synthase Inhibitor, Prevents Ischemia and Reperfusion Injury in Rat Liver Transplantation
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Chlamydia trachomatis induces lncRNA MIAT upregulation to regulate mitochondria‐mediated host cell apoptosis and chlamydial development
inferred← citeshttps://doi.org/10.1155/2017/1035702openalex-snapshot
Capsaicin Protects Cardiomyocytes against Anoxia/Reoxygenation Injury via Preventing Mitochondrial Dysfunction Mediated by SIRT1
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Effects of Beta-Adrenoceptors Overexpression on Cell Survival Are Mediated by Bax/Bcl-2 Pathway in Rat Cardiac Myocytes
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Apoptotic-Related Protein Expression in the Diaphragm and the Effect of Dopamine During Inspiratory Resistance Loading
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Microarray Analysis of Cytokine Activation of Apoptosis Pathways in the Thyroid
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Luteolin Limits Infarct Size and Improves Cardiac Function after Myocardium Ischemia/Reperfusion Injury in Diabetic Rats
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Anti-Inflammatory Effect of Unsaturated Fatty Acids and Ergosta-7,22-dien-3-ol from Marthasterias glacialis: Prevention of CHOP-Mediated ER-Stress and NF-κB Activation
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Influence of nitric oxide metabolites and markers of apoptosis on restenosis of the reconstruction zone after hybrid interventions
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Apoptosis and Cell Proliferation Markers in Inflammatory-Fibroproliferative Diseases of the Vessel Wall (Review)
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Bleaching of the Cnidarian-Dinoflagellate Symbiosis: Aspects of Innate Immunity and the Role of Nitric Oxide
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Bleaching of the Cnidarian-Dinoflagellate Symbiosis: Aspects of Innate Immunity and the Role of Nitric Oxide
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The effectiveness of treadmill and swimming exercise in an animal model of osteoarthritis
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Ginsenoside Rg3 inhibit hepatocellular carcinoma growthviaintrinsic apoptotic pathway
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Pramipexole, a dopamine D3/D2 receptor-preferring agonist, attenuates reserpine-induced fibromyalgia-like model in mice
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