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Nutritive, Post-ingestive Signals Are the Primary Regulators of AgRP Neuron Activity

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1001/jama.2012.116975openalex-snapshot
Effects of Fructose vs Glucose on Regional Cerebral Blood Flow in Brain Regions Involved With Appetite and Reward Pathways
inferredcites →https://doi.org/10.1016/0016-5085(85)90211-2openalex-snapshot
Human distribution and release of a putative new gut hormone, peptide YY
inferredcites →https://doi.org/10.1016/0031-9384(74)90112-7openalex-snapshot
Peripheral control of food intake: Interaction between test diet and postingestive chemoreception☆
inferredcites →https://doi.org/10.1016/0031-9384(84)90235-xopenalex-snapshot
Comparison of gastric, duodenal and jejunal contributions to the inhibition of food intake in the rat
inferredcites →https://doi.org/10.1016/0031-9384(89)90011-5openalex-snapshot
Flavor preferences conditioned by intragastric fat infusions in rats
inferredcites →https://doi.org/10.1016/0195-6663(87)90021-3openalex-snapshot
Lithium chloride, cholecystokinin and meal patterns: Evidence that cholecystokinin suppresses meal size in rats without causing malaise
inferredcites →https://doi.org/10.1016/0300-9084(88)90191-5openalex-snapshot
A possible physiological function of pancreatic pro-colipase activation peptide in appetite regulation
inferredcites →https://doi.org/10.1016/0361-9230(86)90192-9openalex-snapshot
Combined injection potentiates the satiety effects of pancreatic glucagon, cholecystokinin and bombesin
inferredcites →https://doi.org/10.1016/j.bbrc.2006.09.033openalex-snapshot
Differential hypothalamic neuronal activation following peripheral injection of GLP-1 and oxyntomodulin in mice detected by manganese-enhanced magnetic resonance imaging
inferredcites →https://doi.org/10.1016/j.cell.2014.05.017openalex-snapshot
Natural Neural Projection Dynamics Underlying Social Behavior
inferredcites →https://doi.org/10.1016/j.cell.2015.01.033openalex-snapshot
Sensory Detection of Food Rapidly Modulates Arcuate Feeding Circuits
inferredcites →https://doi.org/10.1016/j.cell.2015.07.014openalex-snapshot
Intact-Brain Analyses Reveal Distinct Information Carried by SNc Dopamine Subcircuits
inferredcites →https://doi.org/10.1016/j.cmet.2012.06.015openalex-snapshot
Hindbrain Neurons as an Essential Hub in the Neuroanatomically Distributed Control of Energy Balance
inferredcites →https://doi.org/10.1016/j.cmet.2015.07.011openalex-snapshot
Palatability Can Drive Feeding Independent of AgRP Neurons
inferredcites →https://doi.org/10.1016/j.cmet.2015.10.009openalex-snapshot
Striatal Dopamine Links Gastrointestinal Rerouting to Altered Sweet Appetite
inferredcites →https://doi.org/10.1016/j.neuron.2017.06.014openalex-snapshot
Toward a Wiring Diagram Understanding of Appetite Control
inferredcites →https://doi.org/10.1016/j.neuron.2017.09.043openalex-snapshot
Dynamics of Gut-Brain Communication Underlying Hunger
inferredcites →https://doi.org/10.1016/j.neuropharm.2011.12.022openalex-snapshot
The role of nausea in food intake and body weight suppression by peripheral GLP-1 receptor agonists, exendin-4 and liraglutide
inferredcites →https://doi.org/10.1016/j.peptides.2011.12.004openalex-snapshot
Gastrin releasing peptide-29 requires vagal and splanchnic neurons to evoke satiation and satiety
inferredcites →https://doi.org/10.1016/j.physbeh.2004.04.037openalex-snapshot
Gastric satiation is volumetric, intestinal satiation is nutritive
inferredcites →https://doi.org/10.1016/j.physbeh.2006.08.018openalex-snapshot
Brainstem mechanisms integrating gut-derived satiety signals and descending forebrain information in the control of meal size
inferredcites →https://doi.org/10.1016/s0016-5085(76)80490-8openalex-snapshot
Immunohistochemical Identification of the Cholecystokinin Cell in the Intestinal Mucosa
inferredcites →https://doi.org/10.1016/s0031-9384(98)00110-3openalex-snapshot
Synergy between amylin and cholecystokinin for inhibition of food intake in mice
inferredcites →https://doi.org/10.1016/s0031-9384(98)00274-1openalex-snapshot
Flavor Preferences Conditioned by High-Fat versus High-Carbohydrate Diets Vary as a Function of Session Length
inferredcites →https://doi.org/10.1016/s0889-1591(03)00133-8openalex-snapshot
Conditioned taste aversion with lipopolysaccharide and peptidoglycan does not activate cytokine gene expression in the spleen and hypothalamus of mice
inferredcites →https://doi.org/10.1037/0735-7044.120.4.952openalex-snapshot
Forebrain structures specifically activated by conditioned taste aversion.
inferredcites →https://doi.org/10.1037/h0033692openalex-snapshot
Conditioned satiety in the rat.
inferredcites →https://doi.org/10.1038/266196a0openalex-snapshot
Cholecystokinin produces bait shyness in rats
inferredcites →https://doi.org/10.1038/nature00887openalex-snapshot
Gut hormone PYY3-36 physiologically inhibits food intake
inferredcites →https://doi.org/10.1038/nature11846openalex-snapshot
Concurrent activation of striatal direct and indirect pathways during action initiation
inferredcites →https://doi.org/10.1038/nature12596openalex-snapshot
Genetic identification of a neural circuit that suppresses appetite
inferredcites →https://doi.org/10.1038/nature14190openalex-snapshot
Nutrient-sensing mechanisms and pathways
inferredcites →https://doi.org/10.1038/nature14416openalex-snapshot
Neurons for hunger and thirst transmit a negative-valence teaching signal
inferredcites →https://doi.org/10.1038/nn.2739openalex-snapshot
AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training
inferredcites →https://doi.org/10.1038/nn.4224openalex-snapshot
Separate circuitries encode the hedonic and nutritional values of sugar
inferredcites →https://doi.org/10.1038/sj.ijo.0802696openalex-snapshot
Effects of PYY[3–36] in rodent models of diabetes and obesity
inferredcites →https://doi.org/10.1126/science.1115524openalex-snapshot
NPY/AgRP Neurons Are Essential for Feeding in Adult Mice but Can Be Ablated in Neonates
inferredcites →https://doi.org/10.1126/science.1117255openalex-snapshot
Obestatin, a Peptide Encoded by the Ghrelin Gene, Opposes Ghrelin's Effects on Food Intake
inferredcites →https://doi.org/10.1126/science.275.5306.1593openalex-snapshot
A Neural Substrate of Prediction and Reward
inferredcites →https://doi.org/10.1126/science.6836286openalex-snapshot
Conditioned Cues Elicit Feeding in Sated Rats: A Role for Learning in Meal Initiation
inferredcites →https://doi.org/10.1146/annurev-neuro-072116-031109openalex-snapshot
Neural Circuitry of Reward Prediction Error
inferredcites →https://doi.org/10.1152/ajpregu.1978.235.1.r29openalex-snapshot
Accuracy of the regulation of caloric ingestion in the rhesus monkey
inferredcites →https://doi.org/10.1152/ajpregu.1979.236.5.r254openalex-snapshot
Calories and gastric emptying: a regulatory capacity with implications for feeding
inferredcites →https://doi.org/10.1172/jci30227openalex-snapshot
Gastrointestinal regulation of food intake
inferredcites →https://doi.org/10.1172/jci46229openalex-snapshot
Rapid, reversible activation of AgRP neurons drives feeding behavior in mice
inferredcites →https://doi.org/10.1172/jci4901openalex-snapshot
The cholecystokinin-A receptor mediates inhibition of food intake yet is not essential for the maintenance of body weight
inferredcites →https://doi.org/10.1210/en.2004-1266openalex-snapshot
The Role of the Vagal Nerve in Peripheral PYY3–36-Induced Feeding Reduction in Rats
inferredcites →https://doi.org/10.1210/en.2004-1397openalex-snapshot
Fasting Induces a Large, Leptin-Dependent Increase in the Intrinsic Action Potential Frequency of Orexigenic Arcuate Nucleus Neuropeptide Y/Agouti-Related Protein Neurons
inferredcites →https://doi.org/10.1210/en.2005-0237openalex-snapshot
Peptide YY3–36 and Glucagon-Like Peptide-17–36 Inhibit Food Intake Additively
inferredcites →https://doi.org/10.1210/en.2005-0473openalex-snapshot
Peripheral Exendin-4 and Peptide YY3–36 Synergistically Reduce Food Intake through Different Mechanisms in Mice
inferredcites →https://doi.org/10.1210/en.2007-0898openalex-snapshot
Combination Therapy with Amylin and Peptide YY[3–36] in Obese Rodents: Anorexigenic Synergy and Weight Loss Additivity
inferredcites →https://doi.org/10.1210/en.2007-1743openalex-snapshot
Caudal Brainstem Processing Is Sufficient for Behavioral, Sympathetic, and Parasympathetic Responses Driven by Peripheral and Hindbrain Glucagon-Like-Peptide-1 Receptor Stimulation
inferredcites →https://doi.org/10.1258/acb.2007.007068openalex-snapshot
Supraphysiological doses of intravenous PYY 3-36 cause nausea, but no additional reduction in food intake
inferredcites →https://doi.org/10.1523/jneurosci.22-19-08748.2002openalex-snapshot
Amygdalo-Hypothalamic Circuit Allows Learned Cues to Override Satiety and Promote Eating
inferredcites →https://doi.org/10.3389/fendo.2014.00058openalex-snapshot
Peptides and Food Intake
inferredcites →https://doi.org/10.7554/elife.07122openalex-snapshot
Arcuate hypothalamic AgRP and putative POMC neurons show opposite changes in spiking across multiple timescales

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Encoding the Glucose Identity by Discrete Hypothalamic Neurons
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inferred← citeshttps://doi.org/10.5281/zenodo.23511221zenodo-depositor-declared
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inferred← citeshttps://doi.org/10.1002/cphy.c190034openalex-snapshot
Systemic and Central Amylin, Amylin Receptor Signaling, and Their Physiological and Pathophysiological Roles in Metabolism
inferred← citeshttps://doi.org/10.1002/cphy.c210002openalex-snapshot
Physiology of Taste Processing in the Tongue, Gut, and Brain
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2020.tb00140.xopenalex-snapshot
Systemic and Central Amylin, Amylin Receptor Signaling, and Their Physiological and Pathophysiological Roles in Metabolism
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2021.tb00188.xopenalex-snapshot
Physiology of Taste Processing in the Tongue, Gut, and Brain
inferred← citeshttps://doi.org/10.1002/oby.24060openalex-snapshot
Obesity‐ and diet‐induced plasticity in systems that control eating and energy balance
inferred← citeshttps://doi.org/10.1007/s00018-020-03458-2openalex-snapshot
The neuroscience of sugars in taste, gut-reward, feeding circuits, and obesity
inferred← citeshttps://doi.org/10.1007/s00424-024-03047-3openalex-snapshot
Novel neural pathways targeted by GLP-1R agonists and bariatric surgery
inferred← citeshttps://doi.org/10.1007/s10304-024-00590-1openalex-snapshot
Rolle des Hypothalamus bei der Steuerung des Essverhaltens
inferred← citeshttps://doi.org/10.1007/s11154-025-09990-5openalex-snapshot
Emerging role of AgRP neurons as integrators of metabolic, sensory and environmental cues in the control of energy homeostasis
inferred← citeshttps://doi.org/10.1007/s11892-022-01478-9openalex-snapshot
Gut Factors Mediating the Physiological Impact of Bariatric Surgery
inferred← citeshttps://doi.org/10.1007/s13679-026-00722-7openalex-snapshot
Synergistic Intervention for Obesity: Integrating Central Appetite Regulation and Peripheral Energy Expenditure
inferred← citeshttps://doi.org/10.1016/j.ajcnut.2023.05.003openalex-snapshot
The Neurobiology of Eating Behavior in Obesity: Mechanisms and Therapeutic Targets: A Report from the 23rd Annual Harvard Nutrition Obesity Symposium
inferred← citeshttps://doi.org/10.1016/j.appet.2022.105965openalex-snapshot
Creating the amylin story
inferred← citeshttps://doi.org/10.1016/j.appet.2022.106146openalex-snapshot
Brain regulation of hunger and motivation: The case for integrating homeostatic and hedonic concepts and its implications for obesity and addiction
inferred← citeshttps://doi.org/10.1016/j.appet.2022.106274openalex-snapshot
The impact of caloric availability on eating behavior and ultra-processed food reward
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2022.738917openalex-snapshot
Impact of long-term fasting on the stomach-hypothalamus appetite regulating genes in Atlantic salmon postsmolts
inferred← citeshttps://doi.org/10.1016/j.biochi.2024.10.012openalex-snapshot
Central nervous system pathways targeted by amylin in the regulation of food intake
inferred← citeshttps://doi.org/10.1016/j.biopsych.2022.02.962openalex-snapshot
Development of “Hunger Neurons” and the Unanticipated Relationship Between Energy Metabolism and Mother-Infant Interactions
inferred← citeshttps://doi.org/10.1016/j.brainres.2018.03.027openalex-snapshot
The now and then of gut-brain signaling
inferred← citeshttps://doi.org/10.1016/j.brainres.2018.04.004openalex-snapshot
Roles for gut vagal sensory signals in determining energy availability and energy expenditure
inferred← citeshttps://doi.org/10.1016/j.brainres.2019.04.021openalex-snapshot
Relationship of α-MSH and AgRP axons to the perikarya of melanocortin-4 receptor neurons
inferred← citeshttps://doi.org/10.1016/j.cell.2018.02.057openalex-snapshot
A Neural Circuit for the Suppression of Pain by a Competing Need State
inferred← citeshttps://doi.org/10.1016/j.cell.2018.08.049openalex-snapshot
A Neural Circuit for Gut-Induced Reward
inferred← citeshttps://doi.org/10.1016/j.cell.2019.10.031openalex-snapshot
Genetic Identification of Vagal Sensory Neurons That Control Feeding
inferred← citeshttps://doi.org/10.1016/j.cell.2019.11.040openalex-snapshot
Neural Control and Modulation of Thirst, Sodium Appetite, and Hunger
inferred← citeshttps://doi.org/10.1016/j.cell.2025.01.018openalex-snapshot
Brainstem neuropeptidergic neurons link a neurohumoral axis to satiation
inferred← citeshttps://doi.org/10.1016/j.cell.2025.06.010openalex-snapshot
Brain control of energy homeostasis: Implications for anti-obesity pharmacotherapy
inferred← citeshttps://doi.org/10.1016/j.celrep.2017.11.074openalex-snapshot
AgRP Accountants Compute Caloric Cost
inferred← citeshttps://doi.org/10.1016/j.celrep.2020.02.029openalex-snapshot
Postprandial Hyperglycemia Stimulates Neuroglial Plasticity in Hypothalamic POMC Neurons after a Balanced Meal
inferred← citeshttps://doi.org/10.1016/j.celrep.2021.108755openalex-snapshot
Examining the role of olfaction in dietary choice
inferred← citeshttps://doi.org/10.1016/j.celrep.2021.109845openalex-snapshot
Post-oral sensing of fat increases food intake and attenuates body weight defense
inferred← citeshttps://doi.org/10.1016/j.celrep.2021.109868openalex-snapshot
Deficiency of ER Ca2+ sensor STIM1 in AgRP neurons confers protection against dietary obesity
inferred← citeshttps://doi.org/10.1016/j.celrep.2023.113188openalex-snapshot
Melanocortin-3 receptor expression in AgRP neurons is required for normal activation of the neurons in response to energy deficiency
inferred← citeshttps://doi.org/10.1016/j.celrep.2023.113630openalex-snapshot
Opioidergic signaling contributes to food-mediated suppression of AgRP neurons
inferred← citeshttps://doi.org/10.1016/j.celrep.2024.113675openalex-snapshot
Sucrose overconsumption impairs AgRP neuron dynamics and promotes palatable food intake
inferred← citeshttps://doi.org/10.1016/j.cmet.2018.10.016openalex-snapshot
Defined Paraventricular Hypothalamic Populations Exhibit Differential Responses to Food Contingent on Caloric State
inferred← citeshttps://doi.org/10.1016/j.cmet.2018.12.006openalex-snapshot
Food Intake Recruits Orosensory and Post-ingestive Dopaminergic Circuits to Affect Eating Desire in Humans
inferred← citeshttps://doi.org/10.1016/j.cmet.2019.01.017openalex-snapshot
A Long-Acting PYY3–36 Analog Mediates Robust Anorectic Efficacy with Minimal Emesis in Nonhuman Primates
inferred← citeshttps://doi.org/10.1016/j.cmet.2019.11.016openalex-snapshot
NTS Catecholamine Neurons Mediate Hypoglycemic Hunger via Medial Hypothalamic Feeding Pathways
inferred← citeshttps://doi.org/10.1016/j.cmet.2020.12.018openalex-snapshot
Hypothalamic detection of macronutrients via multiple gut-brain pathways
inferred← citeshttps://doi.org/10.1016/j.cmet.2021.02.014openalex-snapshot
The nerve not taken
inferred← citeshttps://doi.org/10.1016/j.cmet.2023.03.002openalex-snapshot
A synaptic amplifier of hunger for regaining body weight in the hypothalamus
inferred← citeshttps://doi.org/10.1016/j.cmet.2024.11.009openalex-snapshot
Acute and circadian feedforward regulation of agouti-related peptide hunger neurons
inferred← citeshttps://doi.org/10.1016/j.coemr.2022.100337openalex-snapshot
Appetite to learn: An allostatic role for AgRP neurons in the maintenance of energy balance
inferred← citeshttps://doi.org/10.1016/j.conb.2020.03.006openalex-snapshot
Vagal sensory neurons and gut-brain signaling
inferred← citeshttps://doi.org/10.1016/j.conb.2020.03.007openalex-snapshot
Layers of signals that regulate appetite
inferred← citeshttps://doi.org/10.1016/j.conb.2025.103045openalex-snapshot
Molecular mechanisms of stimulus detection and secretion in enteroendocrine cells
inferred← citeshttps://doi.org/10.1016/j.conb.2025.103074openalex-snapshot
What’s the occasion? Phasic dopamine signaling and interoception
inferred← citeshttps://doi.org/10.1016/j.conb.2025.103127openalex-snapshot
Gut-brain reinforcement: Insights from investigations in humans and in rodents
inferred← citeshttps://doi.org/10.1016/j.cophys.2019.10.015openalex-snapshot
Oxytocin neurons: integrators of hypothalamic and brainstem circuits in the regulation of macronutrient-specific satiety
inferred← citeshttps://doi.org/10.1016/j.cub.2018.10.027openalex-snapshot
Neuroscience: To Eat or to Sleep?
inferred← citeshttps://doi.org/10.1016/j.cub.2021.06.048openalex-snapshot
Hypothalamic control of interoceptive hunger
inferred← citeshttps://doi.org/10.1016/j.cub.2022.09.017openalex-snapshot
Hypothalamic AgRP neurons exert top-down control on systemic TNF-α release during endotoxemia
inferred← citeshttps://doi.org/10.1016/j.cub.2025.08.014openalex-snapshot
Age-specific regulation of sociability by hypothalamic Agrp neurons
inferred← citeshttps://doi.org/10.1016/j.cub.2025.11.020openalex-snapshot
High-fat food reinforces risk taking by suppressing defensive neurons
inferred← citeshttps://doi.org/10.1016/j.devcel.2020.10.024openalex-snapshot
Tyramine Acts Downstream of Neuronal XBP-1s to Coordinate Inter-tissue UPRER Activation and Behavior in C. elegans
inferred← citeshttps://doi.org/10.1016/j.isci.2022.104605openalex-snapshot
Local Drd1-neurons input to subgroups of arcuate AgRP/NPY-neurons
inferred← citeshttps://doi.org/10.1016/j.molmet.2018.08.011openalex-snapshot
Cellular and synaptic reorganization of arcuate NPY/AgRP and POMC neurons after exercise
inferred← citeshttps://doi.org/10.1016/j.molmet.2020.101070openalex-snapshot
Nutrient sensing in the nucleus of the solitary tract mediates non-aversive suppression of feeding via inhibition of AgRP neurons
inferred← citeshttps://doi.org/10.1016/j.molmet.2021.101206openalex-snapshot
The melanocortin pathway and energy homeostasis: From discovery to obesity therapy
inferred← citeshttps://doi.org/10.1016/j.molmet.2021.101352openalex-snapshot
Time and metabolic state-dependent effects of GLP-1R agonists on NPY/AgRP and POMC neuronal activity in vivo
inferred← citeshttps://doi.org/10.1016/j.molmet.2023.101745openalex-snapshot
Exercise-induced hypothalamic neuroplasticity: Implications for energy and glucose metabolism
inferred← citeshttps://doi.org/10.1016/j.molmet.2023.101803openalex-snapshot
Acute inhibition of hunger-sensing AgRP neurons promotes context-specific learning in mice
inferred← citeshttps://doi.org/10.1016/j.molmet.2023.101826openalex-snapshot
Ghrelin signalling in AgRP neurons links metabolic state to the sensory regulation of AgRP neural activity
inferred← citeshttps://doi.org/10.1016/j.molmet.2023.101833openalex-snapshot
AgRP neuron activity promotes associations between sensory and nutritive signals to guide flavor preference
inferred← citeshttps://doi.org/10.1016/j.molmet.2024.101975openalex-snapshot
Hypothalamic AgRP neurons regulate the hyperphagia of lactation
inferred← citeshttps://doi.org/10.1016/j.molmet.2024.102021openalex-snapshot
Dietary fat content and absorption shape standard diet devaluation through hunger circuits
inferred← citeshttps://doi.org/10.1016/j.molmet.2024.102025openalex-snapshot
Hunger signalling in the olfactory bulb primes exploration, food-seeking and peripheral metabolism
inferred← citeshttps://doi.org/10.1016/j.molmet.2024.102078openalex-snapshot
Regulation of energy balance by leptin as an adiposity signal and modulator of the reward system
inferred← citeshttps://doi.org/10.1016/j.molmet.2025.102167openalex-snapshot
Reduced liver mitochondrial energy metabolism impairs food intake regulation following gastric preloads and fasting
inferred← citeshttps://doi.org/10.1016/j.molmet.2025.102313openalex-snapshot
Pancreatic amylin dynamically reconfigures distributed brain networks governing appetite regulation in mice
inferred← citeshttps://doi.org/10.1016/j.molmet.2026.102372openalex-snapshot
AgRP neuron activity predicts and tracks the glycemic response to oral glucose
inferred← citeshttps://doi.org/10.1016/j.neuint.2019.04.010openalex-snapshot
GLP-1: Molecular mechanisms and outcomes of a complex signaling system
inferred← citeshttps://doi.org/10.1016/j.neuron.2019.05.050openalex-snapshot
Natural and Drug Rewards Engage Distinct Pathways that Converge on Coordinated Hypothalamic and Reward Circuits
inferred← citeshttps://doi.org/10.1016/j.neuron.2020.03.009openalex-snapshot
Postingestive Modulation of Food Seeking Depends on Vagus-Mediated Dopamine Neuron Activity
inferred← citeshttps://doi.org/10.1016/j.neuron.2021.08.036openalex-snapshot
Cellular activity in insular cortex across seconds to hours: Sensations and predictions of bodily states
inferred← citeshttps://doi.org/10.1016/j.neuron.2023.06.006openalex-snapshot
Toggling between food-seeking and self-preservation behaviors via hypothalamic response networks
inferred← citeshttps://doi.org/10.1016/j.neuron.2024.07.017openalex-snapshot
Negative feedback control of hypothalamic feeding circuits by the taste of food
inferred← citeshttps://doi.org/10.1016/j.neuron.2024.09.011openalex-snapshot
Holistic inside and outside: The impact of food taste on ARCAGRP neuron activity in feeding regulation
inferred← citeshttps://doi.org/10.1016/j.neuron.2025.03.010openalex-snapshot
The neurobiology of overeating
inferred← citeshttps://doi.org/10.1016/j.neuron.2025.05.024openalex-snapshot
Encoding the glucose identity by discrete hypothalamic neurons via the gut-brain axis
inferred← citeshttps://doi.org/10.1016/j.neuron.2025.11.026openalex-snapshot
Intestinal interoception: A nexus of environment-body-brain interactions
inferred← citeshttps://doi.org/10.1016/j.neuron.2025.12.033openalex-snapshot
Exercise-induced activation of ventromedial hypothalamic steroidogenic factor-1 neurons mediates improvements in endurance
inferred← citeshttps://doi.org/10.1016/j.neuron.2026.05.010openalex-snapshot
A hypothalamic circuit for anticipating future changes in energy balance
inferred← citeshttps://doi.org/10.1016/j.neuron.2026.05.013openalex-snapshot
Attenuated hypothalamic response to fructose via a dedicated gut-brain pathway
inferred← citeshttps://doi.org/10.1016/j.neuropharm.2020.107987openalex-snapshot
Salmon calcitonin distributes into the arcuate nucleus to a subset of NPY neurons in mice
inferred← citeshttps://doi.org/10.1016/j.neuropharm.2025.110587openalex-snapshot
Role of amylin in feeding and satiation
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2020.06.005openalex-snapshot
Inhibition of Itch by Hunger and AgRP Neuron Activity
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2021.12.016openalex-snapshot
Specificity of Varenicline in Blocking Mesolimbic Circuit Activation to Natural and Drug Rewards
inferred← citeshttps://doi.org/10.1016/j.npep.2024.102454openalex-snapshot
Chemogenetic activation of arcuate nucleus NPY and NPY/AgRP neurons increases feeding behaviour in mice
inferred← citeshttps://doi.org/10.1016/j.peptides.2020.170366openalex-snapshot
Amylin brain circuitry
inferred← citeshttps://doi.org/10.1016/j.physbeh.2018.02.011openalex-snapshot
Homeostatic and non-homeostatic controls of feeding behavior: Distinct vs. common neural systems
inferred← citeshttps://doi.org/10.1016/j.physbeh.2020.113039openalex-snapshot
Effects of metabolic state on the regulation of melanocortin circuits
inferred← citeshttps://doi.org/10.1016/j.semcdb.2023.07.009openalex-snapshot
Vagal sensory pathway for the gut-brain communication
inferred← citeshttps://doi.org/10.1016/j.tem.2020.04.006openalex-snapshot
Integrating Hunger with Rival Motivations
inferred← citeshttps://doi.org/10.1016/j.tics.2025.05.008openalex-snapshot
The interoceptive origin of reinforcement learning
inferred← citeshttps://doi.org/10.1016/j.tins.2018.05.003openalex-snapshot
Peripheral and Central Nutrient Sensing Underlying Appetite Regulation
inferred← citeshttps://doi.org/10.1016/j.yfrne.2021.100944openalex-snapshot
Rolling out physical exercise and energy homeostasis: Focus on hypothalamic circuitries
inferred← citeshttps://doi.org/10.1038/s41380-022-01932-wopenalex-snapshot
AgRP neurons coordinate the mitigation of activity-based anorexia
inferred← citeshttps://doi.org/10.1038/s41467-020-20093-4openalex-snapshot
An excitatory ventromedial hypothalamus to paraventricular thalamus circuit that suppresses food intake
inferred← citeshttps://doi.org/10.1038/s41467-024-46427-0openalex-snapshot
microRNA-33 controls hunger signaling in hypothalamic AgRP neurons
inferred← citeshttps://doi.org/10.1038/s41575-023-00891-zopenalex-snapshot
Effects of dietary fibre on metabolic health and obesity
inferred← citeshttps://doi.org/10.1038/s41575-026-01203-xopenalex-snapshot
The critical role of gut–brain signalling in eating behaviour and obesity
inferred← citeshttps://doi.org/10.1038/s41583-022-00613-5openalex-snapshot
The neural basis of sugar preference
inferred← citeshttps://doi.org/10.1038/s41583-023-00736-3openalex-snapshot
Defensive responses: behaviour, the brain and the body
inferred← citeshttps://doi.org/10.1038/s41586-019-1053-2openalex-snapshot
Chemosensory modulation of neural circuits for sodium appetite
inferred← citeshttps://doi.org/10.1038/s41586-020-2167-2openalex-snapshot
A neural circuit mechanism for mechanosensory feedback control of ingestion
inferred← citeshttps://doi.org/10.1038/s41586-021-03729-3openalex-snapshot
Food cue regulation of AGRP hunger neurons guides learning
inferred← citeshttps://doi.org/10.1038/s41586-021-04143-5openalex-snapshot
Reverse-translational identification of a cerebellar satiation network
inferred← citeshttps://doi.org/10.1038/s41586-022-05266-zopenalex-snapshot
Gut–brain circuits for fat preference
inferred← citeshttps://doi.org/10.1038/s41586-022-05525-zopenalex-snapshot
A microbiome-dependent gut–brain pathway regulates motivation for exercise
inferred← citeshttps://doi.org/10.1038/s41586-024-08108-2openalex-snapshot
Leptin-activated hypothalamic BNC2 neurons acutely suppress food intake
inferred← citeshttps://doi.org/10.1038/s41586-025-09602-xopenalex-snapshot
A parabrachial hub for need-state control of enduring pain
inferred← citeshttps://doi.org/10.1038/s41593-020-0684-9openalex-snapshot
High-fat food biases hypothalamic and mesolimbic expression of consummatory drives
inferred← citeshttps://doi.org/10.1038/s41593-021-00982-7openalex-snapshot
The preference for sugar over sweetener depends on a gut sensor cell
inferred← citeshttps://doi.org/10.1038/s41593-023-01482-6openalex-snapshot
AgRP neurons encode circadian feeding time
inferred← citeshttps://doi.org/10.1038/s41593-023-01508-zopenalex-snapshot
Daily feeding entrains hunger-sensing neurons
inferred← citeshttps://doi.org/10.1038/s41598-024-70870-0openalex-snapshot
Acute elevated dietary fat alone is not sufficient to decrease AgRP projections in the paraventricular nucleus of the hypothalamus in mice
inferred← citeshttps://doi.org/10.1038/s42255-022-00611-yopenalex-snapshot
Acts of appetite: neural circuits governing the appetitive, consummatory, and terminating phases of feeding
inferred← citeshttps://doi.org/10.1038/s42255-023-00816-9openalex-snapshot
Brain responses to nutrients are severely impaired and not reversed by weight loss in humans with obesity: a randomized crossover study
inferred← citeshttps://doi.org/10.1038/s42255-023-00859-yopenalex-snapshot
Liraglutide restores impaired associative learning in individuals with obesity
inferred← citeshttps://doi.org/10.1038/s42255-025-01301-1openalex-snapshot
A food-sensitive olfactory circuit drives anticipatory satiety
inferred← citeshttps://doi.org/10.1038/s42255-025-01405-8openalex-snapshot
Fat sensory cues in early life program central response to food and obesity
inferred← citeshttps://doi.org/10.1038/s44321-026-00416-6openalex-snapshot
Hypothalamic regulation of sepsis-associated anorexia: cytokine and hormonal signalling through AgRP/POMC circuits
inferred← citeshttps://doi.org/10.1039/d5fo02826dopenalex-snapshot
The role of gut microbiota in shaping and modulating dietary preferences in neurological diseases: implications for microbiota-targeted interventions
inferred← citeshttps://doi.org/10.1056/nejmcibr2111841openalex-snapshot
Eliminating the “Hanger” from Hunger
inferred← citeshttps://doi.org/10.1056/nejmra1812053openalex-snapshot
New Neuroscience of Homeostasis and Drives for Food, Water, and Salt
inferred← citeshttps://doi.org/10.1073/pnas.1909340117openalex-snapshot
Control of food approach and eating by a GABAergic projection from lateral hypothalamus to dorsal pons
inferred← citeshttps://doi.org/10.1073/pnas.2004941117openalex-snapshot
Chronic G q signaling in AgRP neurons does not cause obesity
inferred← citeshttps://doi.org/10.1073/pnas.2011140118openalex-snapshot
Network dynamics of hypothalamic feeding neurons
inferred← citeshttps://doi.org/10.1073/pnas.2524926123openalex-snapshot
Olfactory inputs to appetite neurons in the hypothalamus
inferred← citeshttps://doi.org/10.1073/pnas.2604270123openalex-snapshot
A push–pull gut–brain signal regulates flexible learning in Caenorhabditis elegans
inferred← citeshttps://doi.org/10.1080/19490976.2019.1638722openalex-snapshot
Gut microbes and metabolites as modulators of blood-brain barrier integrity and brain health
inferred← citeshttps://doi.org/10.1093/lifemeta/load004openalex-snapshot
Leucine deprivation results in antidepressant effects via GCN2 in AgRP neurons
inferred← citeshttps://doi.org/10.1093/ntr/ntz010openalex-snapshot
Nicotinic Acetylcholine Receptor Signaling in the Hypothalamus: Mechanisms Related to Nicotine’s Effects on Food Intake
inferred← citeshttps://doi.org/10.1101/2021.03.22.436393openalex-snapshot
Metabolic-sensing in AgRP neurons integrates homeostatic state with dopamine signalling in the striatum
inferred← citeshttps://doi.org/10.1101/2023.01.30.526347openalex-snapshot
Temporal regulation of AgRP neurons mediates context-induced feeding
inferred← citeshttps://doi.org/10.1101/2023.11.30.569492openalex-snapshot
Negative feedback control of hunger circuits by the taste of food
inferred← citeshttps://doi.org/10.1101/2024.02.26.582069openalex-snapshot
A parabrachial hub for the prioritization of survival behavior
inferred← citeshttps://doi.org/10.1101/2024.03.18.585583openalex-snapshot
Incretin hormones and pharmacomimetics rapidly inhibit AgRP neuron activity to suppress appetite
inferred← citeshttps://doi.org/10.1101/2025.03.07.642010openalex-snapshot
A neural circuit for rapid control of hunger by arousal
inferred← citeshttps://doi.org/10.1101/2025.04.29.651295openalex-snapshot
Dopamine signaling tracks naturalistic short-term fluctuations in hunger-satiety
inferred← citeshttps://doi.org/10.1101/2025.05.05.652061openalex-snapshot
Age-specific regulation of sociability by hypothalamic Agrp neurons
inferred← citeshttps://doi.org/10.1101/2025.07.13.664597openalex-snapshot
Diet context gates AgRP neuron involvement in Semaglutide-induced weight loss
inferred← citeshttps://doi.org/10.1101/2025.08.22.671837openalex-snapshot
Reduced melanocortin tone mediates increased feeding during pregnancy in mice
inferred← citeshttps://doi.org/10.1101/2025.09.12.675848openalex-snapshot
BDNF receptor balance gates AgRP-to-PVH fiber density and stimulation-evoked feeding across caloric states
inferred← citeshttps://doi.org/10.1101/2025.10.16.682711openalex-snapshot
A line attractor maintains aggressiveness during feeding in “hangry” mice
inferred← citeshttps://doi.org/10.1101/2025.11.20.689576openalex-snapshot
Aging reveals divergent responses of AgRP/NPY neurons to diet in male and female mice
inferred← citeshttps://doi.org/10.1111/bcpt.13427openalex-snapshot
Central control of energy balance by amylin and calcitonin receptor agonists and their potential for treatment of metabolic diseases
inferred← citeshttps://doi.org/10.1111/bph.15189openalex-snapshot
Brain control of appetite during sickness
inferred← citeshttps://doi.org/10.1111/bph.15682openalex-snapshot
Glucagon‐like peptide‐1 (GLP‐1) signalling in the brain: From neural circuits and metabolism to therapeutics
inferred← citeshttps://doi.org/10.1111/dom.14663openalex-snapshot
Growth differentiation factor 15 ( GDF15 ) and semaglutide inhibit food intake and body weight through largely distinct, additive mechanisms
inferred← citeshttps://doi.org/10.1111/ejn.15498openalex-snapshot
AgRP neuronal activity across feeding‐related behaviours
inferred← citeshttps://doi.org/10.1111/febs.15791openalex-snapshot
Hunger‐driven adaptive prioritization of behavior
inferred← citeshttps://doi.org/10.1111/febs.16176openalex-snapshot
AgRP neurons: Regulators of feeding, energy expenditure, and behavior
inferred← citeshttps://doi.org/10.1111/jnc.15991openalex-snapshot
Feeding signals inhibit fluid‐satiation signals in the mouse lateral parabrachial nucleus to increase intake of highly palatable, caloric solutions
inferred← citeshttps://doi.org/10.1111/jne.13389openalex-snapshot
Metabolic sensing in AgRP regulates sucrose preference and dopamine release in the nucleus accumbens
inferred← citeshttps://doi.org/10.1111/jne.70202openalex-snapshot
Altered responses to ghrelin and food cues in AgRP neurons during pregnancy and lactation
inferred← citeshttps://doi.org/10.1111/nmo.70221openalex-snapshot
The Neuroepithelial Landscape of Enterochromaffin Cells Varies Across Gastrointestinal Location
inferred← citeshttps://doi.org/10.1126/science.aat5236openalex-snapshot
A gut-brain neural circuit for nutrient sensory transduction
inferred← citeshttps://doi.org/10.1126/science.aau9973openalex-snapshot
A gut feeling
inferred← citeshttps://doi.org/10.1126/science.abl7121openalex-snapshot
The power of hunger
inferred← citeshttps://doi.org/10.1126/science.abl7398openalex-snapshot
Integrative neurocircuits that control metabolism and food intake
inferred← citeshttps://doi.org/10.1146/annurev-genet-111523-102202openalex-snapshot
From Mammals to Insects: Exploring the Genetic and Neural Basis of Eating Behavior
inferred← citeshttps://doi.org/10.1146/annurev-neuro-112723-032328openalex-snapshot
Neurobiology of Thirst and Hunger Drives
inferred← citeshttps://doi.org/10.1152/ajpendo.00040.2023openalex-snapshot
Obesity wars: may the smell be with you
inferred← citeshttps://doi.org/10.1152/ajpendo.00388.2020openalex-snapshot
Gut-to-brain signals in feeding control
inferred← citeshttps://doi.org/10.1152/ajpheart.00411.2020openalex-snapshot
Activation of hypothalamic AgRP and POMC neurons evokes disparate sympathetic and cardiovascular responses
inferred← citeshttps://doi.org/10.1159/000503147openalex-snapshot
Hypothalamic Structural and Functional Imbalances in Anorexia Nervosa
inferred← citeshttps://doi.org/10.1172/jci.insight.160891openalex-snapshot
Sustained inhibition of NPY/AgRP neuronal activity by FGF1
inferred← citeshttps://doi.org/10.1172/jci130340openalex-snapshot
Extrahypothalamic GABAergic nociceptin–expressing neurons regulate AgRP neuron activity to control feeding behavior
inferred← citeshttps://doi.org/10.1172/jci186652openalex-snapshot
Incretin receptor agonism rapidly inhibits AgRP neurons to suppress food intake in mice
inferred← citeshttps://doi.org/10.1172/jci194744openalex-snapshot
GLP-1 physiology and pharmacology along the gut-brain axis
inferred← citeshttps://doi.org/10.1186/s12929-023-00984-6openalex-snapshot
Butterflies in the gut: the interplay between intestinal microbiota and stress
inferred← citeshttps://doi.org/10.1186/s13578-025-01409-7openalex-snapshot
AgRP mediated calcium Inhibition of feeding via the vagal afferent nerve-brain pathway
inferred← citeshttps://doi.org/10.1186/s40337-026-01582-1openalex-snapshot
Changes in agouti-related protein and symptom improvement in drug-naïve Chinese female patients with anorexia nervosa: a 6-month real-world longitudinal study
inferred← citeshttps://doi.org/10.1210/en.2018-00131openalex-snapshot
Carnitine Acetyltransferase in AgRP Neurons Is Required for the Homeostatic Adaptation to Restricted Feeding in Male Mice
inferred← citeshttps://doi.org/10.1210/en.2019-00056openalex-snapshot
Regulation of feeding related behaviours by Arcuate neuropeptide Y neurons
inferred← citeshttps://doi.org/10.1210/endocr/bqab029openalex-snapshot
Monitoring In Vivo Neural Activity to Understand Gut–Brain Signaling
inferred← citeshttps://doi.org/10.1210/endocr/bqaf121openalex-snapshot
Neuroendocrinology and the Genetics of Obesity
inferred← citeshttps://doi.org/10.1371/journal.pbio.3000482openalex-snapshot
The homeostatic dynamics of feeding behaviour identify novel mechanisms of anorectic agents
inferred← citeshttps://doi.org/10.1515/nf-2019-0014openalex-snapshot
The gut-brain axis: microglia in the spotlight
inferred← citeshttps://doi.org/10.1523/jneurosci.0190-22.2022openalex-snapshot
Modulating the Excitability of Olfactory Output Neurons Affects Whole-Body Metabolism
inferred← citeshttps://doi.org/10.1523/jneurosci.0589-19.2019openalex-snapshot
Hunger-Activated AgRP Neurons Inhibit MPOA Neurons Controlling Parenting
inferred← citeshttps://doi.org/10.1523/jneurosci.0704-23.2023openalex-snapshot
Paraventricular ThalamicMC3RCircuits Link Energy Homeostasis with Anxiety-Related Behavior
inferred← citeshttps://doi.org/10.1523/jneurosci.0958-18.2018openalex-snapshot
AGRP Neurons Project to the Medial Preoptic Area and Modulate Maternal Nest-Building
inferred← citeshttps://doi.org/10.1530/joe-18-0596openalex-snapshot
The melanocortin pathway and control of appetite-progress and therapeutic implications
inferred← citeshttps://doi.org/10.21203/rs.3.rs-538169/v1openalex-snapshot
Ghrelin Treatment Induces Rapid and Delayed Increments of Food Intake: A Heuristic Model to Explain Ghrelin’s Orexigenic Effects
inferred← citeshttps://doi.org/10.2478/dine-2021-0008openalex-snapshot
The expression of POMC and AgRP in brain and kidney tissues at different stages of diabetic nephropathy rats
inferred← citeshttps://doi.org/10.32657/10220/47424openalex-snapshot
Motor and non-motor control by neuronal subpopulations within the deep cerebellum
inferred← citeshttps://doi.org/10.3389/fnana.2021.751839openalex-snapshot
Whole-Brain Mapping of the Expression Pattern of T1R2, a Subunit Specific to the Sweet Taste Receptor
inferred← citeshttps://doi.org/10.3389/fnins.2023.1272955openalex-snapshot
Enteroendocrine cell regulation of the gut-brain axis
inferred← citeshttps://doi.org/10.3389/fnut.2019.00190openalex-snapshot
The Ghrelin-AgRP Neuron Nexus in Anorexia Nervosa: Implications for Metabolic and Behavioral Adaptations
inferred← citeshttps://doi.org/10.3389/fphys.2021.720639openalex-snapshot
Regional Expression of npy mRNA Paralogs in the Brain of Atlantic Salmon (Salmo salar, L.) and Response to Fasting
inferred← citeshttps://doi.org/10.3390/app15073590openalex-snapshot
Olfactory Capacity and Obesity: A Narrative Review of the Literature
inferred← citeshttps://doi.org/10.3390/biom15081140openalex-snapshot
Anti-Obesity Mechanisms of Plant and Fungal Polysaccharides: The Impact of Structural Diversity
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