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Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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inferredcites →https://doi.org/10.1128/mcb.23.12.4219-4229.2003openalex-snapshot
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inferredcites →https://doi.org/10.1186/1750-1326-6-16openalex-snapshot
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inferredcites →https://doi.org/10.1242/jcs.113.17.3073openalex-snapshot
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Elimination of Microglia Improves Functional Outcomes Following Extensive Neuronal Loss in the Hippocampus
inferredcites →https://doi.org/10.1523/jneurosci.0849-05.2005openalex-snapshot
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inferredcites →https://doi.org/10.1523/jneurosci.4440-12.2013openalex-snapshot
Regulation of Microglial Proliferation during Chronic Neurodegeneration
inferredcites →https://doi.org/10.1523/jneurosci.4807-10.2011openalex-snapshot
The Small GTPase RhoA Is Required to Maintain Spinal Cord Neuroepithelium Organization and the Neural Stem Cell Pool
inferredcites →https://doi.org/10.1523/jneurosci.5966-09.2010openalex-snapshot
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inferredcites →https://doi.org/10.1679/aohc.60.453openalex-snapshot
Effects of Colchicine on Amoeboid Microglial Cells in the Postnatal Rat Brain.
inferredcites →https://doi.org/10.2174/1389450117666160401123825openalex-snapshot
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inferredcites →https://doi.org/10.3389/fncel.2014.00282openalex-snapshot
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inferredcites →https://doi.org/10.3389/fncel.2014.00314openalex-snapshot
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inferredcites →https://doi.org/10.4161/sgtp.29846openalex-snapshot
Rho-associated coiled-coil containing kinases (ROCK)
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Actin And Microtubules: A Tale of Two Cytoskeletons in Microglial Function
inferred← citeshttps://doi.org/10.1002/glia.24067openalex-snapshot
Morphofunctional programming of microglia requires distinct roles of type II myosins
inferred← citeshttps://doi.org/10.1002/glia.24323openalex-snapshot
Movers and shakers: Microglial dynamics and modulation of neural networks
inferred← citeshttps://doi.org/10.1002/glia.70207openalex-snapshot
CX3CR1 Modulates Migration of Resident Microglia Towards Cortical Laser‐Induced Lesions
inferred← citeshttps://doi.org/10.1002/iid3.900openalex-snapshot
Melatonin regulates microglial polarization to M2 cell via RhoA/ROCK signaling pathway in epilepsy
inferred← citeshttps://doi.org/10.1002/wrna.1678openalex-snapshot
Microexon alternative splicing of small GTPase regulators: Implication in central nervous system diseases
inferred← citeshttps://doi.org/10.1007/s00018-025-05648-2openalex-snapshot
Microglia regulate myelin clearance and cholesterol metabolism after demyelination via interferon regulatory factor 5
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TTC3-Mediated Protein Quality Control, A Potential Mechanism for Cognitive Impairment
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ArhGAP11A mediates amyloid-β generation and neuropathology in an Alzheimer’s disease-like mouse model
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Optogenetic mediated contractility enables reversible control of microglial morphology and migration in vivo
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Exposure to Low-Intensity Blast Increases Clearance of Brain Amyloid Beta
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Cdc42GAP deficiency contributes to the Alzheimer’s disease phenotype
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The Alzheimer’s disease-associated protective Plcγ2-P522R variant promotes immune functions
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Microglia morphological response to mesenchymal stromal cell extracellular vesicles demonstrates EV therapeutic potential for modulating neuroinflammation
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Mycophenolate mofetil reduces the branching of microglial processes
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TNF-mediated neuroinflammation is linked to neuronal necroptosis in Alzheimer's disease hippocampus
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GAK antagonises ROCK-dependent regulation of actomyosin dynamics
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CD11c is not required by microglia to convey neuroprotection after prion infection
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inferred← citeshttps://doi.org/10.3389/fimmu.2021.683026openalex-snapshot
Microglial Morphology Across Distantly Related Species: Phylogenetic, Environmental and Age Influences on Microglia Reactivity and Surveillance States
inferred← citeshttps://doi.org/10.3389/fimmu.2024.1412699openalex-snapshot
The microglial innate immune receptor TREM2 participates in fear memory formation through excessive prelimbic cortical synaptic pruning
inferred← citeshttps://doi.org/10.3389/fncel.2021.661612openalex-snapshot
Pharmacological Modulators of Small GTPases of Rho Family in Neurodegenerative Diseases
inferred← citeshttps://doi.org/10.3389/fnins.2024.1362239openalex-snapshot
Role of microbiota-gut-brain axis in natural aging-related alterations in behavior
inferred← citeshttps://doi.org/10.3389/fnmol.2021.744942openalex-snapshot
MicroRNAs Play a Role in Parkinson’s Disease by Regulating Microglia Function: From Pathogenetic Involvement to Therapeutic Potential
inferred← citeshttps://doi.org/10.3390/biomedicines10020237openalex-snapshot
Profiling Microglia in a Mouse Model of Machado–Joseph Disease
inferred← citeshttps://doi.org/10.3390/biomedicines11123198openalex-snapshot
Rhamnetin Prevents Bradykinin-Induced Expression of Matrix Metalloproteinase-9 in Rat Brain Astrocytes by Suppressing Protein Kinase-Dependent AP-1 Activation
inferred← citeshttps://doi.org/10.3390/cells11132022openalex-snapshot
Microglial Depletion Has No Impact on Disease Progression in a Mouse Model of Machado–Joseph Disease
inferred← citeshttps://doi.org/10.3390/cells11172753openalex-snapshot
Na,K-ATPase Acts as a Beta-Amyloid Receptor Triggering Src Kinase Activation
inferred← citeshttps://doi.org/10.3390/cells12101367openalex-snapshot
The RhoA-ROCK1/ROCK2 Pathway Exacerbates Inflammatory Signaling in Immortalized and Primary Microglia
inferred← citeshttps://doi.org/10.3390/cells9091926openalex-snapshot
Conventional and Non-Conventional Roles of Non-Muscle Myosin II-Actin in Neuronal Development and Degeneration
inferred← citeshttps://doi.org/10.3390/ijms21186676openalex-snapshot
Deleterious Alteration of Glia in the Brain of Alzheimer’s Disease
inferred← citeshttps://doi.org/10.3390/ijms231810432openalex-snapshot
p27kip1 Modulates the Morphology and Phagocytic Activity of Microglia
inferred← citeshttps://doi.org/10.3390/ijms24021599openalex-snapshot
Astrocytic Neuroimmunological Roles Interacting with Microglial Cells in Neurodegenerative Diseases
inferred← citeshttps://doi.org/10.3390/ijms252212391openalex-snapshot
Structure of Full-Length Src Kinase and Its Key Phosphorylated States: Molecular Dynamics Study
inferred← citeshttps://doi.org/10.3390/ijms26199458openalex-snapshot
Utilizing Network Toxicology and Molecular Dynamics Simulations to Efficiently Evaluate the Neurotoxicity and Underlying Mechanisms of the Endocrine-Disrupting Chemical Triclosan
inferred← citeshttps://doi.org/10.3390/ijms27031492openalex-snapshot
Altered Microglia-Neuron Crosstalk and Regional Heterogeneity in Alzheimer’s Disease Revealed by Single-Nucleus RNA Sequencing
inferred← citeshttps://doi.org/10.3390/molecules28155846openalex-snapshot
Elucidation of Pharmacological Mechanism Underlying the Anti-Alzheimer’s Disease Effects of Evodia rutaecarpa and Discovery of Novel Lead Molecules: An In Silico Study
inferred← citeshttps://doi.org/10.3892/etm.2022.11405openalex-snapshot
Ketamine administration ameliorates anesthesia and surgery‑induced cognitive dysfunction via activation of TRPV4 channel opening
inferred← citeshttps://doi.org/10.4103/nrr.nrr-d-24-00284openalex-snapshot
Neuroinflammation revisited through the microglial lens
inferred← citeshttps://doi.org/10.48130/targetome-0026-0035openalex-snapshot
From molecular markers to architectural control: cytoskeletal checkpoints as the decisive state-access layer of the aging microglial targetome
inferred← citeshttps://doi.org/10.6084/m9.figshare.16778487openalex-snapshot
Additional file 7 of TNF-mediated neuroinflammation is linked to neuronal necroptosis in Alzheimer's disease hippocampus
inferred← citeshttps://doi.org/10.6084/m9.figshare.16778490openalex-snapshot
Additional file 8 of TNF-mediated neuroinflammation is linked to neuronal necroptosis in Alzheimer's disease hippocampus
inferred← citeshttps://doi.org/10.64898/2025.12.10.693462openalex-snapshot
Reconstructing developmental and disease progression with sample-level embeddings
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