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Microfluidic reactor with immobilized enzyme-from construction to applications: A review

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Outgoing claims: the papers this work cites, builds on, or argues with.

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Automated Determination of Oxygen‐Dependent Enzyme Kinetics in a Tube‐in‐Tube Flow Reactor
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Molecular and Biological Catalysts Coimmobilization on Electrode by Combining Diazonium Electrografting and Sequential Click Chemistry
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Electroactive, Mediating and Thermosensitive Microgel Useful for Covalent Entrapment of Enzymes and Formation of Sensing Layer in Biosensors
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An improved design to capture magnetic microparticles for capillary electrophoresis based immobilized microenzyme reactors
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Controllable and high‐performance immobilized enzyme reactor: DNA‐directed immobilization of multienzyme in polyamidoamine dendrimer‐functionalized capillaries
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Evaluation of xanthine oxidase inhibitory activity of flavonoids by an online capillary electrophoresis‐based immobilized enzyme microreactor
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Enzyme immobilized on the surface geometry pattern of groove‐typed microchannel reactor enhances continuous flow catalysis
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Polydopamine‐assisted immobilization of trypsin onto monolithic structures for protein digestion
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Screening of aromatase inhibitors in traditional Chinese medicines by electrophoretically mediated microanalysis in a partially filled capillary
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A strategy for screening trypsin inhibitors from traditional Chinese medicine based on a monolithic capillary immobilized enzyme reactor coupled with offline liquid chromatography and mass spectrometry
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Rapid on‐line system for preliminary screening of lipase inhibitors from natural products by integrating capillary electrophoresis with immobilized enzyme microreactor
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Efficient proteolysis using a regenerable metal‐ion chelate immobilized enzyme reactor supported on organic–inorganic hybrid silica monolith
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On‐column tryptic mapping of proteins using metal‐ion‐chelated magnetic silica microspheres by matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry
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Synthesis of a monolithic, micro-immobilised enzyme reactor via click-chemistry
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On-line immobilized acetylcholinesterase microreactor for screening of inhibitors from natural extracts by capillary electrophoresis
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A thiol-ene microfluidic device enabling continuous enzymatic digestion and electrophoretic separation as front-end to mass spectrometric peptide analysis
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Enzymatic hydrolysis of rapeseed oil by Thermomyces lanuginosus lipase: variation of continuous and dispersed phase in a slug flow reactor
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Rapid detection of antibiotic resistance genes in lactic acid bacteria using PMMA-based microreactor arrays
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Immobilized Enzyme Reactors: an Overview of Applications in Drug Discovery from 2008 to 2018
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Development of enzyme immobilized monolith micro-reactors integrated with microfluidic electrochemical cell for the evaluation of enzyme kinetics
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DNA-directed enzyme immobilization on Fe3O4 modified with nitrogen-doped graphene quantum dots as a highly efficient and stable multi-catalyst system
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Lipase enzymatic microreactor in polysaccharide hydrogel: structure and properties
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Enhancement of phenolic compounds oxidation using laccase from Trametes versicolor in a microreactor
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Oxygen transfer rates and requirements in oxidative biocatalysis
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A one-step method to construct a third-generation biosensor based on horseradish peroxidase and gold nanoparticles embedded in silica sol–gel network on gold modified electrode
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Pepsin immobilized in dextran-modified fused-silica capillaries for on-line protein digestion and peptide mapping
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Integrated microfluidic chip for on-line proteome analysis with combination of denaturing and rapid digestion of protein
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Fabrication of immobilized enzyme reactors with pillar arrays into polydimethylsiloxane microchip
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A novel microfluidic aqueous two-phase system with immobilized enzyme enhances cyanidin-3-O-glucoside content in red pigments from mulberry fruits
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Intensification of biodiesel synthesis using zigzag micro-channel reactors
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Enhanced biocatalysis mechanism under microwave irradiation in isoquercitrin production revealed by circular dichroism and surface plasmon resonance spectroscopy
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Glucose microfluidic biosensors based on reversible enzyme immobilization on photopatterned stimuli-responsive polymer
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Immobilization of lipases on hydrophobic supports: immobilization mechanism, advantages, problems, and solutions
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Improving the catalytic performance of laccase using a novel continuous-flow microreactor
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Recent progress of microfluidic reactors for biomedical applications
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Heterogeneous Fenton-like oxidation of pharmaceutical diclofenac by a catalytic iron-oxide ceramic microfiltration membrane
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Recent progress in multienzymes co-immobilization and multienzyme system applications
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Enzyme synthesis of cephalexin in continuous-flow microfluidic device in ATPS environment
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Micromixers—a review on passive and active mixing principles
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Local investigations on the gas-liquid mass transfer around Taylor bubbles flowing in a meandering millimetric square channel
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Continuous and controllable preparation of polyaniline with different reaction media in microreactors for supercapacitor applications
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Small but Perfectly Formed? Successes, Challenges, and Opportunities for Microfluidics in the Chemical and Biological Sciences
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Preparation and evaluation of dual-enzyme microreactor with co-immobilized trypsin and chymotrypsin
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Characterization of an immobilized enzyme reactor for on-line protein digestion
inferredcites →https://doi.org/10.1016/j.eurpolymj.2019.109456openalex-snapshot
Robust immobilized enzyme reactor based on trimethylolpropane trimethacrylate organic monolithic matrix through “thiol-ene” click reaction
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Reversible immobilization of laccase onto metal-ion-chelated magnetic microspheres for bisphenol A removal
inferredcites →https://doi.org/10.1016/j.ijbiomac.2018.02.057openalex-snapshot
DNA-directed trypsin immobilization on a polyamidoamine dendrimer-modified capillary to form a renewable immobilized enzyme microreactor
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Magnetic nanoparticles as versatile carriers for enzymes immobilization: A review
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Naturally-derived biopolymers: Potential platforms for enzyme immobilization
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Immobilization of lipase onto novel constructed polydopamine grafted multiwalled carbon nanotube impregnated with magnetic cobalt and its application in synthesis of fruit flavours
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Synthesis and characterization of Ogataea thermomethanolica alcohol oxidase immobilized on barium ferrite magnetic microparticles
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Microfluidic bioreactors for enzymatic synthesis in packed-bed reactors—Multi-step reactions and upscaling
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Purification and in situ immobilization of lipase from of a mutant of Trichosporon laibacchii using aqueous two-phase systems
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Capillary electrophoresis-based online immobilized enzyme reactor for beta-glucosidase kinetics assays and inhibitors screening
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Click chemistry-assisted antibodies immobilization for immunosensing of CXCL7 chemokine in serum
inferredcites →https://doi.org/10.1016/j.jpba.2018.11.063openalex-snapshot
Rapid proteolytic digestion and peptide separation using monolithic enzyme microreactor coupled with capillary electrophoresis
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Apposition of silica lamellae during growth of spicules in the demosponge Suberites domuncula: Biological/biochemical studies and chemical/biomimetical confirmation
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Heat and mass transfer reduced order modeling approach of droplet microreactor based Lab-on-a-Chip devices
inferredcites →https://doi.org/10.1016/j.molcatb.2014.11.006openalex-snapshot
Ultrasound irradiation accelerates the lipase-catalyzed synthesis of methyl caffeate in an ionic liquid
inferredcites →https://doi.org/10.1016/j.partic.2019.04.006openalex-snapshot
Preparation of large In(OH)3 and In2O3 particles through a seed-mediated growth method in a microreactor
inferredcites →https://doi.org/10.1016/j.procbio.2018.12.007openalex-snapshot
Enzyme immobilization in completely packaged freestanding SU-8 microfluidic channel by electro click chemistry for compact thermal biosensor
inferredcites →https://doi.org/10.1016/j.renene.2020.05.172openalex-snapshot
Fabrication of immobilized Candida rugosa lipase on magnetic Fe3O4-poly(glycidyl methacrylate-co-methacrylic acid) composite as an efficient and recyclable biocatalyst for enzymatic production of biodiesel
inferredcites →https://doi.org/10.1016/j.seppur.2020.117052openalex-snapshot
Insights on the laccase extraction and activity in ionic-liquid-based aqueous biphasic systems
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Microfluidic reactors with immobilized enzymes—Characterization, dividing, perspectives
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Capillary electrophoresis-integrated immobilized enzyme microreactor utilizing single-step in-situ penicillinase-mediated alginate hydrogelation: Application for enzyme assays of penicillinase
inferredcites →https://doi.org/10.1016/j.talanta.2019.01.080openalex-snapshot
Surface modification with highly-homogeneous porous silica layer for enzyme immobilization in capillary enzyme microreactors
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Flow Bioreactors as Complementary Tools for Biocatalytic Process Intensification
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Multienzymatic Nanoassemblies: Recent Progress and Applications
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On-line drug–metabolism system using microsomes encapsulated in a capillary by the sol–gel method and integrated into capillary electrophoresis
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Enzymatic Microreactor-on-a-Chip: Protein Mapping Using Trypsin Immobilized on Porous Polymer Monoliths Molded in Channels of Microfluidic Devices
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Photopatterning Enzymes on Polymer Monoliths in Microfluidic Devices for Steady-State Kinetic Analysis and Spatially Separated Multi-Enzyme Reactions
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An Enzymatic Microreactor Based on Chaotic Micromixing for Enhanced Amperometric Detection in a Continuous Glucose Monitoring Application
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Measuring Dynamics in Weakly Structured Regions of Proteins Using Microfluidics-Enabled Subsecond H/D Exchange Mass Spectrometry
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Anchor Peptide-Mediated Surface Immobilization of a Grubbs-Hoveyda-Type Catalyst for Ring-Opening Metathesis Polymerization
inferredcites →https://doi.org/10.1021/acs.iecr.9b01341openalex-snapshot
DNA-Directed Immobilized Enzymes on Recoverable Magnetic Nanoparticles Shielded in Nucleotide Coordinated Polymers
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Enzymatic Biodiesel Synthesis by the Biphasic Esterification of Oleic Acid and 1-Butanol in Microreactors
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An Anticaffeine Antibody–Oligonucleotide Conjugate for DNA-Directed Immobilization in Environmental Immunoarrays
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Biocatalysis Using Immobilized Enzymes in Continuous Flow for the Synthesis of Fine Chemicals
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A Spring in Performance: Silica Nanosprings Boost Enzyme Immobilization in Microfluidic Channels
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Enzyme Encapsulation in a Porous Hydrogen-Bonded Organic Framework
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Biocatalytic Production of Catechols Using a High Pressure Tube-in-Tube Segmented Flow Microreactor
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The past, present and potential for microfluidic reactor technology in chemical synthesis
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Method for immobilization of living and synthetic cells for high-resolution imaging and single-particle tracking
inferredcites →https://doi.org/10.1039/c0an00353kopenalex-snapshot
Phenol biosensor based on hydrogel microarrays entrapping tyrosinase and quantum dots
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Improvement of proteolytic efficiency towards low-level proteins by an antifouling surface of alumina gel in a microchannel
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A DNA-based strategy for dynamic positional enzyme immobilization inside fused silica microchannels
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Flow chemistry syntheses of natural products
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On-a-chip tryptic digestion of transthyretin: a step toward an integrated microfluidic system for the follow-up of familial transthyretin amyloidosis
inferredcites →https://doi.org/10.1039/c7cs00906bopenalex-snapshot
Continuous flow biocatalysis
inferredcites →https://doi.org/10.1039/c7mh00877eopenalex-snapshot
Patterned superhydrophobic surfaces to process and characterize biomaterials and 3D cell culture
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Polydopamine-mediated preparation of an enzyme-immobilized microreactor for the rapid production of wax ester
inferredcites →https://doi.org/10.1039/c8ay02232aopenalex-snapshot
Screening of α-glucosidase inhibitors from natural flavonoids by an in-capillary assay combining PMMA and EMMA
inferredcites →https://doi.org/10.1039/c8dt04857fopenalex-snapshot
Thermostable enzyme-immobilized magnetic responsive Ni-based metal–organic framework nanorods as recyclable biocatalysts for efficient biosynthesis of S -adenosylmethionine
inferredcites →https://doi.org/10.1039/c9tb02315aopenalex-snapshot
One-pot synthesis of trypsin-based magnetic metal–organic frameworks for highly efficient proteolysis
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Continuous flow microreactor for protein PEGylation
inferredcites →https://doi.org/10.1080/10242422.2019.1611788openalex-snapshot
Enzymatic dimerization of phenylacetylene by laccase immobilized on magnetic nanoparticles via click chemistry
inferredcites →https://doi.org/10.1097/mpa.0000000000001631openalex-snapshot
Platelet Microparticles Regulate Neutrophil Extracellular Traps in Acute Pancreatitis
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Microflow Fluorinations of Benzynes: Efficient Synthesis of Fluoroaromatic Compounds
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Synergy of Microtechnology and Biotechnology: Microreactors as an Effective Tool for Biotransformation Processes
inferredcites →https://doi.org/10.3390/catal8010007openalex-snapshot
Stability, Deactivation, and Regeneration of Chloroaluminate Ionic Liquid as Catalyst for Industrial C4 Alkylation
inferredcites →https://doi.org/10.3390/catal8070282openalex-snapshot
Magnetic Microreactors with Immobilized Enzymes—From Assemblage to Contemporary Applications
inferredcites →https://doi.org/10.3390/mi10010011openalex-snapshot
Proton Irradiation Effects on Hardness and the Volta Potential of Welding 308L Duplex Stainless Steel
inferredcites →https://doi.org/10.3390/mi10110759openalex-snapshot
Kinetic Parameter Estimation and Mathematical Modelling of Lipase Catalysed Biodiesel Synthesis in a Microreactor
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A Review on Mixing in Microfluidics
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Biocatalytic synthesis of the Green Note trans-2-hexenal in a continuous-flow microreactor

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Dual Flow Reactor Approach for the Chemoenzymatic Production of Chenodeoxycholic Acid, a Precursor to Ursodeoxycholic Acid
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Co-Cross-Linked Aggregates of Baeyer–Villiger Monooxygenases and Formate Dehydrogenase for Repeated Use in Asymmetric Biooxidation
inferred← citeshttps://doi.org/10.1021/acssuschemeng.4c09158openalex-snapshot
Hierarchical Porous Silica Aerogel Monoliths for High-Flow Rate Continuous-Flow Enzyme Catalysis
inferred← citeshttps://doi.org/10.1039/d3ra03742hopenalex-snapshot
Immobilised-enzyme microreactors for the identification and synthesis of conjugated drug metabolites
inferred← citeshttps://doi.org/10.1055/s-0043-1763754openalex-snapshot
Gas–Liquid Microchemical Oxidation for Continuous Synthesis Processes: A Short Review
inferred← citeshttps://doi.org/10.1080/10242422.2022.2056450openalex-snapshot
Protease immobilization on activated chitosan/cellulose acetate electrospun nanofibrous polymers: Biochemical characterization and efficient protein waste digestion
inferred← citeshttps://doi.org/10.3390/mi13020311openalex-snapshot
Microfluidic Immobilized Enzymatic Reactors for Proteomic Analyses—Recent Developments and Trends (2017–2021)
inferred← citeshttps://doi.org/10.3390/mi13071146openalex-snapshot
Droplet Microfluidic Device for Chemoenzymatic Sensing
inferred← citeshttps://doi.org/10.3390/pr10030494openalex-snapshot
Enzyme Immobilization and Co-Immobilization: Main Framework, Advances and Some Applications
inferred← citeshttps://doi.org/10.5204/thesis.eprints.240366openalex-snapshot
Integrated enzyme and cofactor engineering in continuous flow biocatalysis
inferred← citeshttps://doi.org/10.53540/tjer.vol19iss2pp106-128openalex-snapshot
DESIGN AND MIXING PERFORMANCE OF PASSIVE MICROMIXERS: A CRITICAL REVIEW
inferred← citeshttps://doi.org/10.70675/c5500b99z18d2z4cf1z8e47z9462799dae9fopenalex-snapshot
Valorisation de l'acide lévulinique par microfluidique : approches théoriques et expérimentales.
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