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Therapeutic strategies of diabetic nephropathy: recent progress and future perspectives

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Outgoing claims: the papers this work cites, builds on, or argues with.

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Mortality in Randomized Trials of Antioxidant Supplements for Primary and Secondary Prevention
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Malaria Treatment in the United States
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Relationship Between Gilbert Syndrome and Prevalence of Vascular Complications in Patients With Diabetes
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The renin-angiotensin-aldosterone system
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The NOX toolbox: validating the role of NADPH oxidases in physiology and disease
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Molecular detection of exercise-induced free radicals following ascorbate prophylaxis in type 1 diabetes mellitus: a randomised controlled trial
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Genetic deficiency of aldose reductase counteracts the development of diabetic nephropathy in C57BL/6 mice
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Novel insights into the structural requirements for the design of selective and specific aldose reductase inhibitors
inferredcites →https://doi.org/10.1007/s10157-013-0874-9openalex-snapshot
Genetic associations in diabetic nephropathy
inferredcites →https://doi.org/10.1007/s11010-011-0826-1openalex-snapshot
Fluorofenidone attenuates renal interstitial fibrosis in the rat model of obstructive nephropathy
inferredcites →https://doi.org/10.1007/s11033-009-9869-8openalex-snapshot
Role of aldose reductase in the high glucose induced expression of fibronectin in human mesangial cells
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Direct renin inhibition: An update
inferredcites →https://doi.org/10.1016/0168-8227(94)90002-7openalex-snapshot
The effect of an aldose reductase inhibitor (Epalrestat) on diabetic nephropathy in rats
inferredcites →https://doi.org/10.1016/0891-5849(90)90070-yopenalex-snapshot
Metabolic activation of natural phenols into selective oxidative burst agonists by activated human neutrophils
inferredcites →https://doi.org/10.1016/j.abb.2006.11.010openalex-snapshot
The oxidation of apocynin catalyzed by myeloperoxidase: Proposal for NADPH oxidase inhibition
inferredcites →https://doi.org/10.1016/j.bbrc.2006.03.114openalex-snapshot
Novel Nox inhibitor of oxLDL-induced reactive oxygen species formation in human endothelial cells
inferredcites →https://doi.org/10.1016/j.bcp.2005.10.036openalex-snapshot
Stereospecific recognition of a spirosuccinimide type aldose reductase inhibitor (AS-3201) by plasma proteins: A significant role of specific binding by serum albumin in the improved potency and stability
inferredcites →https://doi.org/10.1016/j.bmcl.2012.01.073openalex-snapshot
Synthesis and structure–activity relationship of 5-substituent-2(1H)-pyridone derivatives as anti-fibrosis agents
inferredcites →https://doi.org/10.1016/j.cardiores.2006.01.022openalex-snapshot
Novel Nox inhibitor VAS2870 attenuates PDGF-dependent smooth muscle cell chemotaxis, but not proliferation☆
inferredcites →https://doi.org/10.1016/j.cbi.2008.05.003openalex-snapshot
Antioxidant and radical scavenging properties of curcumin
inferredcites →https://doi.org/10.1016/j.coph.2009.11.004openalex-snapshot
Novel aspects of the roles of Rac1 GTPase in the cardiovascular system
inferredcites →https://doi.org/10.1016/j.cytogfr.2011.06.002openalex-snapshot
The role of TGF-β and epithelial-to mesenchymal transition in diabetic nephropathy
inferredcites →https://doi.org/10.1016/j.diabres.2008.10.007openalex-snapshot
Effects of NADPH oxidase inhibitor on diabetic nephropathy in OLETF rats: The role of reducing oxidative stress in its protective property
inferredcites →https://doi.org/10.1016/j.diabres.2011.03.016openalex-snapshot
Improving neuropathy scores in type 2 diabetic patients using micronutrients supplementation
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2005.12.034openalex-snapshot
Aldose reductase inhibition counteracts nitrosative stress and poly(ADP-ribose) polymerase activation in diabetic rat kidney and high-glucose-exposed human mesangial cells
inferredcites →https://doi.org/10.1016/j.mce.2012.10.024openalex-snapshot
Curcumin ameliorates diabetic nephropathy by inhibiting the activation of the SphK1-S1P signaling pathway
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Inflammatory Cells in Renal Injury and Repair
inferredcites →https://doi.org/10.1016/s0010-7824(02)00303-7openalex-snapshot
Male fertility: core chemical structure in pharmacological research
inferredcites →https://doi.org/10.1016/s0014-2999(00)00454-4openalex-snapshot
The inhibition of flavoproteins by phenoxaiodonium, a new iodonium analogue
inferredcites →https://doi.org/10.1016/s0021-9258(17)45256-2openalex-snapshot
Isolation and Properties of Lens Aldose Reductase
inferredcites →https://doi.org/10.1016/s0140-6736(05)67814-2openalex-snapshot
Effect of inhibitors of the renin-angiotensin system and other antihypertensive drugs on renal outcomes: systematic review and meta-analysis
inferredcites →https://doi.org/10.1016/s0140-6736(06)69442-7openalex-snapshot
Oral renin inhibitors
inferredcites →https://doi.org/10.1016/s0140-6736(10)60576-4openalex-snapshot
Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial
inferredcites →https://doi.org/10.1016/s0140-6736(11)60679-xopenalex-snapshot
National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants
inferredcites →https://doi.org/10.1016/s0140-6736(11)60739-3openalex-snapshot
The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial
inferredcites →https://doi.org/10.1016/s0140-6736(13)60687-xopenalex-snapshot
Chronic kidney disease: global dimension and perspectives
inferredcites →https://doi.org/10.1016/s0378-1119(01)00449-8openalex-snapshot
Homologs of gp91 phox : cloning and tissue expression of Nox3, Nox4, and Nox5
inferredcites →https://doi.org/10.1021/jm050462topenalex-snapshot
A Novel Series of Non-Carboxylic Acid, Non-Hydantoin Inhibitors of Aldose Reductase with Potent Oral Activity in Diabetic Rat Models: 6-(5-Chloro-3-methylbenzofuran-2-sulfonyl)-2H-pyridazin-3-one and Congeners
inferredcites →https://doi.org/10.1021/jm100505nopenalex-snapshot
Discovery of (3 S ,3a R )-2-(3-Chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2 H -benzo[ g ]indazole-7-carboxylic Acid (PF-3882845), an Orally Efficacious Mineralocorticoid Receptor (MR) Antagonist for Hypertension and Nephropathy
inferredcites →https://doi.org/10.1021/jm300806copenalex-snapshot
Mineralocorticoid Receptor Antagonists for the Treatment of Hypertension and Diabetic Nephropathy
inferredcites →https://doi.org/10.1021/np100826qopenalex-snapshot
New Synthetic Triterpenoids: Potent Agents for Prevention and Treatment of Tissue Injury Caused by Inflammatory and Oxidative Stress
inferredcites →https://doi.org/10.1023/a:1007023532508openalex-snapshot
Pirfenidone inhibits NADPH-dependent microsomal lipid peroxidation and scavenges hydroxyl radicals
inferredcites →https://doi.org/10.1038/35008121openalex-snapshot
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
inferredcites →https://doi.org/10.1038/414813aopenalex-snapshot
Biochemistry and molecular cell biology of diabetic complications
inferredcites →https://doi.org/10.1038/ki.2009.509openalex-snapshot
Diabetic kidney disease: act now or pay later
inferredcites →https://doi.org/10.1038/ki.2010.265openalex-snapshot
Bilirubin and biliverdin protect rodents against diabetic nephropathy by downregulating NAD(P)H oxidase
inferredcites →https://doi.org/10.1038/nrendo.2010.212openalex-snapshot
Oxidative stress in early diabetic nephropathy: fueling the fire
inferredcites →https://doi.org/10.1038/nrendo.2012.125openalex-snapshot
Treating diabetic nephropathy—still an unresolved issue
inferredcites →https://doi.org/10.1038/nrneph.2011.149openalex-snapshot
Cellular and molecular mechanisms of renal fibrosis
inferredcites →https://doi.org/10.1038/nrneph.2011.51openalex-snapshot
Inflammatory molecules and pathways in the pathogenesis of diabetic nephropathy
inferredcites →https://doi.org/10.1038/nrneph.2014.14openalex-snapshot
Potential approaches to reverse or repair renal fibrosis
inferredcites →https://doi.org/10.1038/sj.ki.5000377openalex-snapshot
Prevalence and risk factors for microalbuminuria in a referred cohort of type II diabetic patients: A global perspective
inferredcites →https://doi.org/10.1038/sj.ki.5001775openalex-snapshot
IN-1130, a novel transforming growth factor-β type I receptor kinase (ALK5) inhibitor, suppresses renal fibrosis in obstructive nephropathy
inferredcites →https://doi.org/10.1038/sj.ki.5002386openalex-snapshot
The role of protein kinase C activation in diabetic nephropathy
inferredcites →https://doi.org/10.1038/sj.ki.5002717openalex-snapshot
Oral administration of GW788388, an inhibitor of TGF-β type I and II receptor kinases, decreases renal fibrosis
inferredcites →https://doi.org/10.1042/bj2900041openalex-snapshot
Studies on the inhibitory mechanism of iodonium compounds with special reference to neutrophil NADPH oxidase
inferredcites →https://doi.org/10.1042/cs20120198openalex-snapshot
Inflammation and the pathogenesis of diabetic nephropathy
inferredcites →https://doi.org/10.1042/cs20120330openalex-snapshot
Renoprotective effects of a novel Nox1/4 inhibitor in a mouse model of Type 2 diabetes
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The effect of sorbinil, an aldose reductase inhibitor, on aortic function in control and streptozotocin‐induced diabetic rats
inferredcites →https://doi.org/10.1046/j.1523-1755.2002.00123.xopenalex-snapshot
Oxidative stress and nitric oxide synthase in rat diabetic nephropathy: Effects of ACEI and ARB
inferredcites →https://doi.org/10.1053/anep.2003.50017openalex-snapshot
Hyperfiltration and glomerulosclerosis
inferredcites →https://doi.org/10.1056/nejmoa1001286openalex-snapshot
Effects of Intensive Blood-Pressure Control in Type 2 Diabetes Mellitus
inferredcites →https://doi.org/10.1056/nejmoa1105351openalex-snapshot
Bardoxolone Methyl and Kidney Function in CKD with Type 2 Diabetes
inferredcites →https://doi.org/10.1056/nejmoa1111732openalex-snapshot
Intensive Diabetes Therapy and Glomerular Filtration Rate in Type 1 Diabetes
inferredcites →https://doi.org/10.1073/pnas.0500815102openalex-snapshot
Extremely potent triterpenoid inducers of the phase 2 response: Correlations of protection against oxidant and inflammatory stress
inferredcites →https://doi.org/10.1074/jbc.274.2.703openalex-snapshot
Alternatively Spliced Variant of Smad2 Lacking Exon 3
inferredcites →https://doi.org/10.1093/eurjhf/hfs033openalex-snapshot
Aliskiren, ALTITUDE, and the Implications for ATMOSPHERE
inferredcites →https://doi.org/10.1093/ndt/gfl780openalex-snapshot
Dual blockade of aldosterone and angiotensin II additively suppresses TGF- and NADPH oxidase in the hypertensive kidney
inferredcites →https://doi.org/10.1093/ndt/gfp150openalex-snapshot
Inhibition of protein kinase C in diabetic nephropathy--where do we stand?
inferredcites →https://doi.org/10.1097/01.asn.0000077408.15865.06openalex-snapshot
Contribution of Polyol Pathway to Diabetes-Induced Oxidative Stress
inferredcites →https://doi.org/10.1097/fjc.0b013e31802b6530openalex-snapshot
Double-Edged Action of SOD Mimetic in Diabetic Nephropathy
inferredcites →https://doi.org/10.1097/hjh.0b013e328338bb11openalex-snapshot
Aliskiren enhances protective effects of valsartan against type 2 diabetic nephropathy in mice
inferredcites →https://doi.org/10.1111/eci.12230openalex-snapshot
Lipid‐lowering treatment and inflammatory mediators in diabetes and chronic kidney disease
inferredcites →https://doi.org/10.1111/j.1440-1681.2006.04468.xopenalex-snapshot
CURCUMIN, THE ACTIVE PRINCIPLE OF TURMERIC (CURCUMA LONGA), AMELIORATES DIABETIC NEPHROPATHY IN RATS
inferredcites →https://doi.org/10.1111/j.1440-1797.2009.01129.xopenalex-snapshot
Fluorofenidone attenuates collagen I and transforming growth factor‐β1 expression through a nicotinamide adenine dinucleotide phosphate oxidase‐dependent way in NRK‐52E cells
inferredcites →https://doi.org/10.1111/j.1464-5491.2007.02097.xopenalex-snapshot
Combination therapy with an ACE inhibitor and an angiotensin receptor blocker for diabetic nephropathy: a meta‐analysis
inferredcites →https://doi.org/10.1111/j.1523-1755.2005.00287.xopenalex-snapshot
Effects of NADPH oxidase inhibitor in diabetic nephropathy
inferredcites →https://doi.org/10.1111/j.1755-5922.2011.00310.xopenalex-snapshot
Opportunity Nox: The Future of NADPH Oxidases as Therapeutic Targets in Cardiovascular Disease
inferredcites →https://doi.org/10.1124/jpet.111.190918openalex-snapshot
Characterization of CCX140-B, an orally bioavailable antagonist of the CCR2 chemokine receptor, for the treatment of type 2 diabetes and associated complications
inferredcites →https://doi.org/10.1126/science.182.4117.1146openalex-snapshot
Polyol Accumulation in Galactosemic and Diabetic Rats: Control by an Aldose Reductase Inhibitor
inferredcites →https://doi.org/10.1139/o96-038openalex-snapshot
Prevention of early glomerulopathy with tolrestat in the streptozotocin-induced diabetic rat
inferredcites →https://doi.org/10.1146/annurev.arplant.55.031903.141701openalex-snapshot
REACTIVE OXYGEN SPECIES: Metabolism, Oxidative Stress, and Signal Transduction
inferredcites →https://doi.org/10.1152/ajpregu.00648.2011openalex-snapshot
Phycocyanin and phycocyanobilin from Spirulina platensis protect against diabetic nephropathy by inhibiting oxidative stress
inferredcites →https://doi.org/10.1152/ajprenal.00028.2010openalex-snapshot
Critical role of Nox4-based NADPH oxidase in glucose-induced oxidative stress in the kidney: implications in type 2 diabetic nephropathy
inferredcites →https://doi.org/10.1152/ajprenal.00507.2012openalex-snapshot
Pirfenidone inhibits macrophage infiltration in 5/6 nephrectomized rats
inferredcites →https://doi.org/10.1155/2014/180270openalex-snapshot
The Role of Transforming Growth Factor-Beta in Diabetic Nephropathy
inferredcites →https://doi.org/10.1159/000065445openalex-snapshot
Effect of Long-Term Administration of Prostaglandin I2 in Incipient Diabetic Nephropathy
inferredcites →https://doi.org/10.1159/000139394openalex-snapshot
Zopolrestat Prevention of Proteinuria, Albuminuria and Cataractogenesis in Diabetes mellitus
inferredcites →https://doi.org/10.1159/000195722openalex-snapshot
Amelioration of Diabetic Nephropathy in OLETF Rats by Prostaglandin I2 Analog, Beraprost Sodium
inferredcites →https://doi.org/10.1159/000259897openalex-snapshot
Anti-Glycation and Anti-Albuminuric Effects of GLY-230 in Human Diabetes
inferredcites →https://doi.org/10.1159/000329080openalex-snapshot
Fluorofenidone Attenuates Tubulointerstitial Fibrosis by Inhibiting TGF-β1-Induced Fibroblast Activation
inferredcites →https://doi.org/10.1159/000329419openalex-snapshot
Fluorofenidone Attenuates Diabetic Nephropathy and Kidney Fibrosis in db/db Mice
inferredcites →https://doi.org/10.1159/000330685openalex-snapshot
Antiproteinuric Effect of Chemokine C-C Motif Ligand 2 Inhibition in Subjects with Acute Proliferative Lupus Nephritis
inferredcites →https://doi.org/10.1161/01.cir.0000156466.02908.edopenalex-snapshot
Aliskiren, a Novel Orally Effective Renin Inhibitor, Provides Dose-Dependent Antihypertensive Efficacy and Placebo-Like Tolerability in Hypertensive Patients
inferredcites →https://doi.org/10.1161/01.hyp.0000255636.11931.a2openalex-snapshot
Podocyte as the Target for Aldosterone
inferredcites →https://doi.org/10.1161/hypertensionaha.107.100214openalex-snapshot
Apocynin Is Not an Inhibitor of Vascular NADPH Oxidases but an Antioxidant
inferredcites →https://doi.org/10.1177/1470320311434818openalex-snapshot
Baseline characteristics in the Aliskiren Trial in Type 2 Diabetes Using Cardio-Renal Endpoints (ALTITUDE)
inferredcites →https://doi.org/10.1183/09031936.00005209openalex-snapshot
Pirfenidone in idiopathic pulmonary fibrosis
inferredcites →https://doi.org/10.1183/09031936.00071710openalex-snapshot
Pirfenidone in idiopathic pulmonary fibrosis: Figure 1–
inferredcites →https://doi.org/10.1196/annals.1333.093openalex-snapshot
Pyridoxamine: The Many Virtues of a Maillard Reaction Inhibitor
inferredcites →https://doi.org/10.1208/s12248-012-9432-8openalex-snapshot
Therapeutic Roles of Curcumin: Lessons Learned from Clinical Trials
inferredcites →https://doi.org/10.1248/bpb.b12-00528openalex-snapshot
A Novel C–C Chemokine Receptor 2 Antagonist Prevents Progression of Albuminuria and Atherosclerosis in Mouse Models
inferredcites →https://doi.org/10.1291/hypres.28.925openalex-snapshot
Cardioprotective Mechanisms of Spironolactone Associated with the Angiotensin-Converting Enzyme/Epidermal Growth Factor Receptor/Extracellular Signal-Regulated Kinases, NAD(P)H Oxidase/Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1, and Rho-Kinase Pathways in Aldosterone/Salt-Induced…
inferredcites →https://doi.org/10.1507/endocrj.k10e-382openalex-snapshot
Sitagliptin reduces albuminuria in patients with type 2 diabetes [Rapid Communication]
inferredcites →https://doi.org/10.1515/bmc.2011.002openalex-snapshot
Aldose reductase: new insights for an old enzyme
inferredcites →https://doi.org/10.1517/13543776.2012.726615openalex-snapshot
Novel aldose reductase inhibitors: a patent survey (2006 – present)
inferredcites →https://doi.org/10.1517/14728222.11.8.1011openalex-snapshot
Suppressing renal NADPH oxidase to treat diabetic nephropathy
inferredcites →https://doi.org/10.1592/phco.28.5.646openalex-snapshot
Epalrestat: An Aldose Reductase Inhibitor for the Treatment of Diabetic Neuropathy
inferredcites →https://doi.org/10.1681/asn.2004110919openalex-snapshot
Independent and Additive Impact of Blood Pressure Control and Angiotensin II Receptor Blockade on Renal Outcomes in the Irbesartan Diabetic Nephropathy Trial
inferredcites →https://doi.org/10.1681/asn.2005070694openalex-snapshot
Deletion of Protein Kinase C-ε Signaling Pathway Induces Glomerulosclerosis and Tubulointerstitial Fibrosis In Vivo
inferredcites →https://doi.org/10.1681/asn.2008090931openalex-snapshot
Pirfenidone Is Renoprotective in Diabetic Kidney Disease
inferredcites →https://doi.org/10.1681/asn.2010020218openalex-snapshot
NF-κB in Renal Inflammation
inferredcites →https://doi.org/10.1681/asn.2010101049openalex-snapshot
Pirfenidone for Diabetic Nephropathy
inferredcites →https://doi.org/10.1681/asn.2011030272openalex-snapshot
Pyridorin in Type 2 Diabetic Nephropathy
inferredcites →https://doi.org/10.2174/157339911794940729openalex-snapshot
Antioxidants in the Treatment of Diabetes
inferredcites →https://doi.org/10.2215/cjn.09321209openalex-snapshot
Phase 1 Study of Anti-CTGF Monoclonal Antibody in Patients with Diabetes and Microalbuminuria
inferredcites →https://doi.org/10.2337/db12-0534openalex-snapshot
Dual Inhibition of Classical Protein Kinase C-α and Protein Kinase C-β Isoforms Protects Against Experimental Murine Diabetic Nephropathy
inferredcites →https://doi.org/10.2337/dc13-0323openalex-snapshot
Linagliptin Lowers Albuminuria on Top of Recommended Standard Treatment in Patients With Type 2 Diabetes and Renal Dysfunction
inferredcites →https://doi.org/10.2337/diacare.28.10.2458openalex-snapshot
Comparison of the Effects of Vitamins and/or Mineral Supplementation on Glomerular and Tubular Dysfunction in Type 2 Diabetes
inferredcites →https://doi.org/10.2337/diacare.28.11.2686openalex-snapshot
The Effect of Ruboxistaurin on Nephropathy in Type 2 Diabetes
inferredcites →https://doi.org/10.3109/00365599.2011.585622openalex-snapshot
Oral supplementation of turmeric attenuates proteinuria, transforming growth factor-β and interleukin-8 levels in patients with overt type 2 diabetic nephropathy: A randomized, double-blind and placebo-controlled study
inferredcites →https://doi.org/10.3390/molecules17021373openalex-snapshot
Design, Synthesis and Anti-fibrosis Activity Study of N1-Substituted Phenylhydroquinolinone Derivatives
inferredcites →https://doi.org/10.3390/molecules18032821openalex-snapshot
Apocynin: Chemical and Biophysical Properties of a NADPH Oxidase Inhibitor
inferredcites →https://doi.org/10.4155/cli.14.19openalex-snapshot
Treatment of albuminuria due to diabetic nephropathy: recent trial results
inferredcites →https://doi.org/10.4161/cc.11.1.18559openalex-snapshot
Bindarit
inferredcites →https://doi.org/10.5772/1297openalex-snapshot
Emerging Research and Treatments in Renal Cell Carcinoma
inferredcites →https://doi.org/10.5772/26747openalex-snapshot
Oxidative Stress and Redox-Signaling in Renal Cell Cancer
inferredcites →https://doi.org/10.7326/0003-4819-142-1-200501040-00110openalex-snapshot
Meta-Analysis: High-Dosage Vitamin E Supplementation May Increase All-Cause Mortality
inferredcites →https://doi.org/10.7326/0003-4819-157-4-201208210-00007openalex-snapshot
Benefits and Harms of Statin Therapy for Persons With Chronic Kidney Disease

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Comparative pharmacokinetics of acteoside from total glycoside extracted from leaves of Rehmannia and Dihuangye total glycoside capsule in normal and diabetic nephropathy rats
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QSAR characterization of new synthesized hydantoins with antiproliferative activity
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β‐Amyrin ameliorates diabetic nephropathy in mice and regulates the miR ‐181b‐5p/ HMGB2 axis in high glucose‐stimulated HK ‐2 cells
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Animal Models of Diabetic Kidney Disease
inferred← citeshttps://doi.org/10.1007/s00592-021-01736-4openalex-snapshot
Klotho protects against diabetic kidney disease via AMPK- and ERK-mediated autophagy
inferred← citeshttps://doi.org/10.1007/s11695-015-1666-yopenalex-snapshot
The Short-Term Remission of Diabetic Nephropathy After Roux-en-Y Gastric Bypass in Chinese Patients of T2DM with Obesity
inferred← citeshttps://doi.org/10.1007/s12272-025-01555-zopenalex-snapshot
Targeting NF-κB in diabetic nephropathy: exploring the therapeutic potential of phytoconstituents
inferred← citeshttps://doi.org/10.1007/s12291-018-0743-0openalex-snapshot
Caffeic Acid Modulates miR-636 Expression in Diabetic Nephropathy Rats
inferred← citeshttps://doi.org/10.1007/s13410-019-00752-zopenalex-snapshot
Administration of coenzyme Q10 to a diabetic rat model: changes in biochemical, antioxidant, and histopathological indicators
inferred← citeshttps://doi.org/10.1016/j.arcmed.2020.05.008openalex-snapshot
Melatonin Ameliorates Renal Fibrosis Through the Inhibition of NF-κB and TGF-β1/Smad3 Pathways in db/db Diabetic Mice
inferred← citeshttps://doi.org/10.1016/j.bcp.2017.12.002openalex-snapshot
CK2α promotes advanced glycation end products-induced expressions of fibronectin and intercellular adhesion molecule-1 via activating MRTF-A in glomerular mesangial cells
inferred← citeshttps://doi.org/10.1016/j.biopha.2017.07.112openalex-snapshot
RETRACTED: Taraxerol, a pentacyclic triterpenoid, from Abroma augusta leaf attenuates diabetic nephropathy in type 2 diabetic rats
inferred← citeshttps://doi.org/10.1016/j.biopha.2018.02.105openalex-snapshot
Involvement of growth factors in diabetes mellitus and its complications: A general review
inferred← citeshttps://doi.org/10.1016/j.biopha.2018.08.002openalex-snapshot
Omentin-1 protects renal function of mice with type 2 diabetic nephropathy via regulating miR-27a-Nrf2/Keap1 axis
inferred← citeshttps://doi.org/10.1016/j.biopha.2020.109926openalex-snapshot
Protective effects and mechanisms of Rehmannia glutinosa leaves total glycoside on early kidney injury in db/db mice
inferred← citeshttps://doi.org/10.1016/j.biopha.2021.111918openalex-snapshot
New progress in drugs treatment of diabetic kidney disease
inferred← citeshttps://doi.org/10.1016/j.bmcl.2020.127490openalex-snapshot
Discovery of a coumarin derivative as Nrf2 activator mitigating oxidative stress and fibrosis in mesangial cells under high glucose
inferred← citeshttps://doi.org/10.1016/j.cis.2023.102889openalex-snapshot
Nanostructured supports for multienzyme co-immobilization for biotechnological applications: Achievements, challenges and prospects
inferred← citeshttps://doi.org/10.1016/j.cyto.2015.11.023openalex-snapshot
Blockade of TGF-β-activated kinase 1 prevents advanced glycation end products-induced inflammatory response in macrophages
inferred← citeshttps://doi.org/10.1016/j.cyto.2021.155774openalex-snapshot
Inflammatory cytokines and retinal nonperfusion area in quiescent proliferative diabetic retinopathy
inferred← citeshttps://doi.org/10.1016/j.ejphar.2015.02.045openalex-snapshot
Experimental evidence for curcumin and its analogs for management of diabetes mellitus and its associated complications
inferred← citeshttps://doi.org/10.1016/j.ejphar.2020.173574openalex-snapshot
Ferroptosis involves in renal tubular cell death in diabetic nephropathy
inferred← citeshttps://doi.org/10.1016/j.fshw.2022.04.036openalex-snapshot
Antioxidant effect of Lactobacillus fermentum HFY02-fermented soy milk on D-galactose-induced aging mouse model
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2017.06.070openalex-snapshot
Combination of coenzyme Q10-loaded liposomes with ultrasound targeted microbubbles destruction (UTMD) for early theranostics of diabetic nephropathy
inferred← citeshttps://doi.org/10.1016/j.intimp.2018.03.019openalex-snapshot
Inhibitor of Bruton's tyrosine kinases, PCI-32765, decreases pro-inflammatory mediators' production in high glucose-induced macrophages
inferred← citeshttps://doi.org/10.1016/j.intimp.2019.106120openalex-snapshot
2-Dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione, isolated from the root of Averrhoa carambola L., protects against diabetic kidney disease by inhibiting TLR4/TGFβ signaling pathway
inferred← citeshttps://doi.org/10.1016/j.isci.2024.108868openalex-snapshot
Nox4-SH3YL1 complex is involved in diabetic nephropathy
inferred← citeshttps://doi.org/10.1016/j.jep.2016.05.033openalex-snapshot
Huangkui capsule, an extract from Abelmoschus manihot (L.) medic, improves diabetic nephropathy via activating peroxisome proliferator–activated receptor (PPAR)-α/γ and attenuating endoplasmic reticulum stress in rats
inferred← citeshttps://doi.org/10.1016/j.jff.2018.09.020openalex-snapshot
Naringin ameliorates experimental diabetic renal fibrosis by inhibiting the ERK1/2 and JNK MAPK signaling pathways
inferred← citeshttps://doi.org/10.1016/j.jff.2021.104403openalex-snapshot
Betacyanins attenuates diabetic nephropathy in mice by inhibiting fibrosis and oxidative stress via the improvement of Nrf2 signaling
inferred← citeshttps://doi.org/10.1016/j.metabol.2018.01.002openalex-snapshot
IL-6 receptor blockade ameliorates diabetic nephropathy via inhibiting inflammasome in mice
inferred← citeshttps://doi.org/10.1016/j.nano.2023.102696openalex-snapshot
Novel pH-responsive E-selectin targeting natural polysaccharides hybrid micelles for diabetic nephropathy
inferred← citeshttps://doi.org/10.1016/j.phrs.2018.10.030openalex-snapshot
Salvia miltiorrhiza protects against diabetic nephropathy through metabolome regulation and wnt/β-catenin and TGF-β signaling inhibition
inferred← citeshttps://doi.org/10.1016/j.phrs.2019.01.043openalex-snapshot
Diabetic nephropathy: The regulatory interplay between epigenetics and microRNAs
inferred← citeshttps://doi.org/10.1016/j.phrs.2020.104831openalex-snapshot
Astragaloside IV acts through multi-scale mechanisms to effectively reduce diabetic nephropathy
inferred← citeshttps://doi.org/10.1016/j.phymed.2018.04.031openalex-snapshot
Carnosic acid improves diabetic nephropathy by activating Nrf2/ARE and inhibition of NF-κB pathway
inferred← citeshttps://doi.org/10.1021/acs.jafc.2c03286openalex-snapshot
Aronia melanocarpa Anthocyanin Extracts Improve Hepatic Structure and Function in High-Fat Diet-/Streptozotocin-Induced T2DM Mice
inferred← citeshttps://doi.org/10.1038/cddis.2017.292openalex-snapshot
Interleukin-22 ameliorated renal injury and fibrosis in diabetic nephropathy through inhibition of NLRP3 inflammasome activation
inferred← citeshttps://doi.org/10.1038/s12276-020-0381-5openalex-snapshot
Long noncoding RNA NEAT1 is involved in the protective effect of Klotho on renal tubular epithelial cells in diabetic kidney disease through the ERK1/2 signaling pathway
inferred← citeshttps://doi.org/10.1038/s41598-025-10305-6openalex-snapshot
Bidirectional Mendelian randomization analysis of the causal associations between serum vitamin D levels and multiple kidney diseases
inferred← citeshttps://doi.org/10.1039/c9ra05046aopenalex-snapshot
Effects of Bailing capsule on diabetic nephropathy based on UPLC-MS urine metabolomics
inferred← citeshttps://doi.org/10.1080/08923973.2020.1725039openalex-snapshot
Alantolactone mitigates renal injury induced by diabetes via inhibition of high glucose-mediated inflammatory response and macrophage infiltration
inferred← citeshttps://doi.org/10.1080/13880209.2017.1412467openalex-snapshot
Total flavones of Abelmoschus manihot improve diabetic nephropathy by inhibiting the iRhom2/TACE signalling pathway activity in rats
inferred← citeshttps://doi.org/10.1080/21691401.2019.1640231openalex-snapshot
Arbutin protects HK-2 cells against high glucose-induced apoptosis and autophagy by up-regulating microRNA-27a
inferred← citeshttps://doi.org/10.1097/maj.0000000000000510openalex-snapshot
Synergistic Effects of Combining Anti-Midkine and Hepatocyte Growth Factor Therapies Against Diabetic Nephropathy in Rats
inferred← citeshttps://doi.org/10.1097/md.0000000000027569openalex-snapshot
Efficacy and safety of Huangkui capsule for diabetic nephropathy
inferred← citeshttps://doi.org/10.1111/1753-0407.12420openalex-snapshot
Effect of the oral iron chelator deferiprone in diabetic nephropathy rats
inferred← citeshttps://doi.org/10.1111/cbdd.70015openalex-snapshot
Chromone Derivatives as a Novel NOX4 Inhibitor: Design, Synthesis, and Regulation of ROS in Renal Fibroblast
inferred← citeshttps://doi.org/10.1111/jcmm.17065openalex-snapshot
Exosomal hsa_circ_0125310 promotes cell proliferation and fibrosis in diabetic nephropathy via sponging miR‐422a and targeting the IGF1R/p38 axis
inferred← citeshttps://doi.org/10.1111/jpi.12296openalex-snapshot
Melatonin nephroprotective action in Zucker diabetic fatty rats involves its inhibitory effect on NADPH oxidase
inferred← citeshttps://doi.org/10.1155/2016/1634730openalex-snapshot
Rapid Identification of Potential Drugs for Diabetic Nephropathy Using Whole-Genome Expression Profiles of Glomeruli
inferred← citeshttps://doi.org/10.1155/2018/6806943openalex-snapshot
Clinical Efficacy of Jinshuibao Capsules Combined with Angiotensin Receptor Blockers in Patients with Early Diabetic Nephropathy: A Meta‐Analysis of Randomized Controlled Trials
inferred← citeshttps://doi.org/10.1155/2020/7950457openalex-snapshot
WJ-39, an Aldose Reductase Inhibitor, Ameliorates Renal Lesions in Diabetic Nephropathy by Activating Nrf2 Signaling
inferred← citeshttps://doi.org/10.1155/2021/6669352openalex-snapshot
α‐Lipoic Acid Increases Collagen Synthesis and Deposition in Nondiabetic and Diabetic Rat Kidneys
inferred← citeshttps://doi.org/10.1155/2022/5063636openalex-snapshot
Liuwei Dihuang Pill Attenuates Diabetic Nephropathy by Inhibiting Renal Fibrosis via TGF-β/Smad2/3 Pathway
inferred← citeshttps://doi.org/10.1159/000448043openalex-snapshot
Combination of Sitagliptin and Insulin against Type 2 Diabetes Mellitus with Neuropathy in Rats: Neuroprotection and Role of Oxidative and Inflammation Stress
inferred← citeshttps://doi.org/10.1167/iovs.66.5.46openalex-snapshot
Potential Application of Bendazac L-Lysine for Controlling Myopia Progression, as Demonstrated in Two Experimental Guinea Pig Myopia Models
inferred← citeshttps://doi.org/10.1248/bpb.b15-00127openalex-snapshot
Relaxin Inhibits High Glucose-Induced Matrix Accumulation in Human Mesangial Cells by Interfering with TGF-β1 Production and Mesangial Cells Phenotypic Transition
inferred← citeshttps://doi.org/10.1900/rds.2015.12.134openalex-snapshot
Targeting Mitochondria and Reactive Oxygen Species-Driven Pathogenesis in Diabetic Nephropathy
inferred← citeshttps://doi.org/10.21203/rs.3.rs-3956527/v1openalex-snapshot
ALA/LA Inhibited Renal Tubulointerstitial Fibrosis of DKD db/db Mice Induced by Oxidative Stress
inferred← citeshttps://doi.org/10.2147/dmso.s195456openalex-snapshot
Quercetin improves lipid metabolism via SCAP-SREBP2-LDLr signaling pathway in early stage diabetic nephropathy
inferred← citeshttps://doi.org/10.23878/medicina.v22i2.877openalex-snapshot
Funcionalidad familiar y enfermedad renal diabética
inferred← citeshttps://doi.org/10.26599/fmh.2026.9420115openalex-snapshot
“Medicine food homology” plants in the treatment of diabetic nephropathy: pathogenic pathways and therapeutic approaches
inferred← citeshttps://doi.org/10.3389/fbioe.2022.870049openalex-snapshot
Nano-Technological Approaches for Targeting Kidney Diseases With Focus on Diabetic Nephropathy: Recent Progress, and Future Perspectives
inferred← citeshttps://doi.org/10.3389/fphar.2017.00798openalex-snapshot
NF-κβ: A Potential Target in the Management of Vascular Complications of Diabetes
inferred← citeshttps://doi.org/10.3389/fphar.2018.01012openalex-snapshot
Protective Effects of Total Glycoside From Rehmannia glutinosa Leaves on Diabetic Nephropathy Rats via Regulating the Metabolic Profiling and Modulating the TGF-β1 and Wnt/β-Catenin Signaling Pathway
inferred← citeshttps://doi.org/10.3389/fphar.2020.01068openalex-snapshot
Traditional Uses, Chemical Constituents, Biological Properties, Clinical Settings, and Toxicities of Abelmoschus manihot L.: A Comprehensive Review
inferred← citeshttps://doi.org/10.3389/fphar.2020.534775openalex-snapshot
Fluorofenidone Alleviates Renal Fibrosis by Inhibiting Necroptosis Through RIPK3/MLKL Pathway
inferred← citeshttps://doi.org/10.3389/fphar.2022.987668openalex-snapshot
Multi-omics analysis reveals the pathogenesis of db/db mice diabetic kidney disease and the treatment mechanisms of multi-bioactive compounds combination from Salvia miltiorrhiza
inferred← citeshttps://doi.org/10.3389/fphys.2015.00247openalex-snapshot
The protective effects of oral low-dose quercetin on diabetic nephropathy in hypercholesterolemic mice
inferred← citeshttps://doi.org/10.3390/molecules26030696openalex-snapshot
Okra (Abelmoschus Esculentus) as a Potential Dietary Medicine with Nutraceutical Importance for Sustainable Health Applications
inferred← citeshttps://doi.org/10.3390/molecules27092913openalex-snapshot
Effects of Cadmium on Physiochemistry and Bioactive Substances of Muskmelon (Cucumis melo L.)
inferred← citeshttps://doi.org/10.3390/molecules27185784openalex-snapshot
Terpenoids from the Seeds of Toona sinensis and Their Ability to Attenuate High Glucose-Induced Oxidative Stress and Inflammation in Rat Glomerular Mesangial Cells
inferred← citeshttps://doi.org/10.3390/molecules29112610openalex-snapshot
Optimization of Flavonoid Extraction from Abelmoschus manihot Flowers Using Ultrasonic Techniques: Predictive Modeling through Response Surface Methodology and Deep Neural Network and Biological Activity Assessment
inferred← citeshttps://doi.org/10.3390/pharmaceutics18010094openalex-snapshot
DOTAP-Based Hybrid Nanostructured Lipid Carriers for CRISPR–Cas9 RNP Delivery Targeting TGFB1 in Diabetic Nephropathy
inferred← citeshttps://doi.org/10.37766/inplasy2021.6.0057openalex-snapshot
Efficacy and safety of Huangkui capsule for diabetic nephropathy A protocol for systematic review and meta-analysis
inferred← citeshttps://doi.org/10.3892/etm.2021.10422openalex-snapshot
Saxagliptin protects against diabetic nephropathy by inhibiting caspase 3/PARP‑1‑dependent nephrocyte apoptosis
inferred← citeshttps://doi.org/10.4062/biomolther.2019.188openalex-snapshot
Function of NADPH Oxidases in Diabetic Nephropathy and Development of Nox Inhibitors
inferred← citeshttps://doi.org/10.4155/fmc-2019-0111openalex-snapshot
Current Advances in Idiopathic Pulmonary Fibrosis: The pathogenesis, Therapeutic Strategies and Candidate Molecules
inferred← citeshttps://doi.org/10.4239/wjd.v15.i1.105openalex-snapshot
Myricetin induces M2 macrophage polarization to alleviate renal tubulointerstitial fibrosis in diabetic nephropathy via PI3K/Akt pathway
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