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Recent advances in natural products from plants for treatment of liver diseases
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/mnfr.201100374openalex-snapshotThe protective role of natural phytoalexin resveratrol on inflammation, fibrosis and regeneration in cholestatic liver injury
inferredcites →https://doi.org/10.1007/s00204-002-0346-6openalex-snapshotWogonin and fisetin induction of apoptosis through activation of caspase 3 cascade and alternative expression of p21 protein in hepatocellular carcinoma cells SK-HEP-1
inferredcites →https://doi.org/10.1007/s10620-006-3177-0openalex-snapshotA Long-Term Glycyrrhizin Injection Therapy Reduces Hepatocellular Carcinogenesis Rate in Patients with Interferon-Resistant Active Chronic Hepatitis C: A Cohort Study of 1249 Patients
inferredcites →https://doi.org/10.1007/s11655-006-0268-1openalex-snapshotEffect of Compound Glycyrrhizin Injection on liver function and cellular immunity of children with infectious mononucleosis complicated liver impairment
inferredcites →https://doi.org/10.1016/j.bcp.2005.07.025openalex-snapshotGenipin-induced apoptosis in hepatoma cells is mediated by reactive oxygen species/c-Jun NH2-terminal kinase-dependent activation of mitochondrial pathway
inferredcites →https://doi.org/10.1016/j.ejmech.2011.09.022openalex-snapshotIdentification of human IKK-2 inhibitors of natural origin (Part II): In Silico prediction of IKK-2 inhibitors in natural extracts with known anti-inflammatory activity
inferredcites →https://doi.org/10.1016/j.ejmech.2011.12.015openalex-snapshotStructure-based virtual screening for plant-derived SdiA-selective ligands as potential antivirulent agents against uropathogenic Escherichia coli
inferredcites →https://doi.org/10.1016/j.jpba.2011.01.042openalex-snapshotPotential role of metabolomics apporoaches in the area of traditional Chinese medicine: As pillars of the bridge between Chinese and Western medicine
inferredcites →https://doi.org/10.1016/j.jpba.2011.09.033openalex-snapshotMetabolomic study of insomnia and intervention effects of Suanzaoren decoction using ultra-performance liquid-chromatography/electrospray-ionization synapt high-definition mass spectrometry
inferredcites →https://doi.org/10.1021/np100826qopenalex-snapshotNew Synthetic Triterpenoids: Potent Agents for Prevention and Treatment of Tissue Injury Caused by Inflammatory and Oxidative Stress
inferredcites →https://doi.org/10.1039/c1an15752copenalex-snapshotPharmacokinetics screening for multi-components absorbed in the rat plasma after oral administration traditional Chinese medicine formula Yin-Chen-Hao-Tang by ultra performance liquid chromatography-electrospray ionization/quadrupole-time-of-flight mass spectrometry combined with pattern…
inferredcites →https://doi.org/10.1039/c1an15833copenalex-snapshotMetabolomics study on Fuzi and its processed products using ultra-performance liquid-chromatography/electrospray-ionization synapt high-definition mass spectrometry coupled with pattern recognition analysis
inferredcites →https://doi.org/10.1073/pnas.0712365105openalex-snapshotDissection of mechanisms of Chinese medicinal formula Realgar- Indigo naturalis as an effective treatment for promyelocytic leukemia
inferredcites →https://doi.org/10.1124/jpet.111.182592openalex-snapshotGlycyrrhizin Prevents Liver Injury by Inhibition of High-Mobility Group Box 1 Production by Kupffer Cells after Ischemia-Reperfusion in Rats
inferredcites →https://doi.org/10.1152/ajpendo.00332.2010openalex-snapshotRhein ameliorates fatty liver disease through negative energy balance, hepatic lipogenic regulation, and immunomodulation in diet-induced obese mice
inferredcites →https://doi.org/10.1155/2011/703676openalex-snapshotResveratrol Regulates Antioxidant Status, Inhibits Cytokine Expression and Restricts Apoptosis in Carbon Tetrachloride Induced Rat Hepatic Injury
inferredcites →https://doi.org/10.1211/jpp.60.1.0012openalex-snapshotGlycyrrhizin prevents of lipopolysaccharide/D-galactosamine-induced liver injury through down-regulation of matrix metalloproteinase-9 in mice
inferredcites →https://doi.org/10.1211/jpp.61.10.0016openalex-snapshotPotential beneficial effect of naringenin on lipid peroxidation and antioxidant status in rats with ethanol-induced hepatotoxicity
inferredcites →https://doi.org/10.1211/jpp/61.10.0016openalex-snapshotPotential beneficial effect of naringenin on lipid peroxidation and antioxidant status in rats with ethanol-induced hepatotoxicity
inferredcites →https://doi.org/10.1248/bpb.34.1613openalex-snapshotPreventive Effect of Geniposide on Metabolic Disease Status in Spontaneously Obese Type 2 Diabetic Mice and Free Fatty Acid-Treated HepG2 Cells
inferredcites →https://doi.org/10.3892/mmr.2011.555openalex-snapshotResveratrol interferes with N-nitrosodiethylamine-induced hepatocellular carcinoma at early and advanced stages in male Wistar rats
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.3897/pharmacia.72.e152827zenodo-depositor-declaredIn vitro activity of two cycloartane-type triterpenoid saponins from Astragalus glycyphyllos on liver microsomes, hepatocytes, and isoforms of cytochrome P450
inferred← citeshttps://doi.org/10.1002/bmc.3060openalex-snapshotSerum pharmacochemistry combined with multiple data processing approach to screen the bioactive components and their metabolites in Mutan Cortex by ultra‐performance liquid chromatography tandem mass spectrometry
inferred← citeshttps://doi.org/10.1002/cbdv.202500691openalex-snapshotHepatoprotective Potential of Phyllanthus niruri Extracts Against CCl 4 ‐Induced Liver Injury in Rats: Insight From Phytochemical Profiling, Molecular Docking, and Oxidative Stress Studies
inferred← citeshttps://doi.org/10.1002/jssc.201300742openalex-snapshotImproved ultra‐performance liquid chromatography with electrospray ionization quadrupole‐time‐of‐flight high‐definition mass spectrometry method for the rapid analysis of the chemical constituents of a typical medical formula: Liuwei Dihuang Wan
inferred← citeshttps://doi.org/10.1002/jssc.201600812openalex-snapshotRapid discovery of absorbed constituents and metabolites in rat plasma after the oral administration of Zi Shen Wan using high‐throughput UHPLC–MS with a multivariate analysis approach
inferred← citeshttps://doi.org/10.1002/ptr.6251openalex-snapshotHepatoprotective and antioxidant potential of Pycnogenol® in acetaminophen‐induced hepatotoxicity in rats
inferred← citeshttps://doi.org/10.1002/ptr.6396openalex-snapshotA chemically characterized ethanolic extract of Thai Perilla frutescens (L.) Britton fruits (nutlets) reduces oxidative stress and lipid peroxidation in human hepatoma (HuH7) cells
inferred← citeshttps://doi.org/10.1002/ptr.7584openalex-snapshotHypolipogenic effects of Icariside E4 via phosphorylation of AMPK and inhibition of MID1IP1 in HepG2 cells
inferred← citeshttps://doi.org/10.1007/s00284-026-04802-8openalex-snapshotSynergistic Interaction Between Alkanna tinctoria (L.) Tausch and Cefixime Enhances Antibacterial Activity Against Resistant Bacterial Strains
inferred← citeshttps://doi.org/10.1007/s11240-017-1292-6openalex-snapshotA viable alternative in vitro system and comparative metabolite profiling of different tissues for the conservation of Ceropegia karulensis
inferred← citeshttps://doi.org/10.1007/s11356-018-2820-6openalex-snapshotRETRACTED ARTICLE: Carbon tetrachloride induced hepato/renal toxicity in experimental mice: antioxidant potential of Egyptian Salvia officinalis L essential oil
inferred← citeshttps://doi.org/10.1007/s13105-014-0323-6openalex-snapshotAqueous date fruit extract protects against lipid peroxidation and improves antioxidant status in the liver of rats subchronically exposed to trichloroacetic acid
inferred← citeshttps://doi.org/10.1007/s13213-014-0968-yopenalex-snapshotBiotransformation of geniposide by Synechocystis sp. PCC 6803 into genipin and its inhibitory effects on BEL-7402, Escherichia coli, and cyanobacteria
inferred← citeshttps://doi.org/10.1007/s13346-023-01315-wopenalex-snapshotResponse surface optimization of a cardioprotective compound through pharmacosomal drug delivery system: in vivo bioavailability and cardioprotective activity potential
inferred← citeshttps://doi.org/10.1007/s13410-024-01350-4openalex-snapshotThe effect of oral consumption of sesame oil on anthropometric, metabolic and oxidative stress markers of patients with type 2 diabetes: a double-blind, randomized controlled trial
inferred← citeshttps://doi.org/10.1007/s40495-026-00467-wopenalex-snapshotInvestigating Albizia procera as a Natural Source of Bioactive Compounds: Phytochemistry, Pharmacological Activities, and Therapeutic Prospects in Disease Management
inferred← citeshttps://doi.org/10.1016/j.biopha.2020.110348openalex-snapshot1,2,3,4,6 penta-O-galloyl-β-D-glucose ameliorates high-fat diet-induced nonalcoholic fatty liver disease and maintains the expression of genes involved in lipid homeostasis in mice
inferred← citeshttps://doi.org/10.1016/j.chmed.2019.12.004openalex-snapshotRole of semi-purified andrographolide from Andrographis paniculata extract as nano-phytovesicular carrier for enhancing oral absorption and hypoglycemic activity
inferred← citeshttps://doi.org/10.1016/j.eng.2018.11.008openalex-snapshotChinmedomics: A Powerful Approach Integrating Metabolomics with Serum Pharmacochemistry to Evaluate the Efficacy of Traditional Chinese Medicine
inferred← citeshttps://doi.org/10.1016/j.etap.2014.01.026openalex-snapshotTherapeutic potential of morin against liver fibrosis in rats: Modulation of oxidative stress, cytokine production and nuclear factor kappa B
inferred← citeshttps://doi.org/10.1016/j.fbio.2024.103746openalex-snapshotA Pueraria lobata root extract alleviates high-fat diet-induced non-alcoholic fatty liver disease by modulating the gut microbiota and associated metabolites
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2019.11.088openalex-snapshotHippophae rhamnoides polysaccharides protect IPEC-J2 cells from LPS-induced inflammation, apoptosis and barrier dysfunction in vitro via inhibiting TLR4/NF-κB signaling pathway
inferred← citeshttps://doi.org/10.1016/j.ijms.2015.04.004openalex-snapshotCharacterization of in vitro primary metabolic profile of SKLB-M8, a novel antitumor compound, using liquid chromatography coupled with triple quadrupole tandem mass spectrometry and quadrupole time-of-flight tandem mass spectrometry
inferred← citeshttps://doi.org/10.1016/j.indcrop.2015.03.030openalex-snapshotComposition, antioxidant, antimicrobial and enzyme inhibition activities of two Origanum vulgare subspecies (subsp. vulgare and subsp. hirtum) essential oils
inferred← citeshttps://doi.org/10.1016/j.jep.2017.07.027openalex-snapshotProtective effects of flavonoids isolated from Korean milk thistle Cirsium japonicum var. maackii (Maxim.) Matsum on tert -butyl hydroperoxide-induced hepatotoxicity in HepG2 cells
inferred← citeshttps://doi.org/10.1016/j.jep.2023.117349openalex-snapshotIntegrating serum pharmacochemistry and network pharmacology to explore the molecular mechanisms of Acanthopanax senticosus (Rupr. & Maxim.) Harms on attenuating doxorubicin-induced myocardial injury
inferred← citeshttps://doi.org/10.1016/j.jep.2025.120886openalex-snapshotIntegrated transcriptomics and network pharmacology approaches to elucidate the anti-fibrotic mechanism of Eucommia ulmoides leaves against liver fibrosis
inferred← citeshttps://doi.org/10.1016/j.jep.2026.122201openalex-snapshotBabaodan ameliorates metabolic dysfunction-associated steatotic liver disease with co-modulation of FXR, NF-κB, and SLC22A7 in bile acid metabolism
inferred← citeshttps://doi.org/10.1016/j.jff.2018.06.028openalex-snapshotPotential health advantages of Periploca laevigata: Preliminary phytochemical analysis and evaluation of in vitro antioxidant capacity and assessment of hepatoprotective, anti-inflammatory and analgesic effects
inferred← citeshttps://doi.org/10.1016/j.jff.2023.105455openalex-snapshotHydroxytyrosol ameliorates LPS-induced acute liver injury (ALI) in mice by modulating the balance between M1/M2 phenotype macrophage and inhibiting TLR4/NF-κB activation
inferred← citeshttps://doi.org/10.1016/j.jpba.2018.02.033openalex-snapshotIdentification, characterization and HPLC quantification of formulation-related impurities of honokiol, an antitumor natural drug candidate in clinical trials
inferred← citeshttps://doi.org/10.1016/j.jtcme.2015.07.005openalex-snapshotSynergistic hepatoprotective potential of ethanolic extract of Solanum xanthocarpum and Juniperus communis against paracetamol and azithromycin induced liver injury in rats
inferred← citeshttps://doi.org/10.1016/j.phymed.2025.157077openalex-snapshotHerbal mixture of Platycodon grandiflorum, Cinnamomum cassia, and Asiasarum sieboldii extracts protects against NASH progression via regulation of hepatic steatosis, inflammation, and apoptosis
inferred← citeshttps://doi.org/10.1016/j.prenap.2024.100048openalex-snapshotExploration of the pharmacological mechanism of herbal medicines against hepatic disorder: A systematic review and network pharmacological analysis
inferred← citeshttps://doi.org/10.1016/j.prp.2024.155663openalex-snapshottrans-chalcone ameliorates CCl4-induced acute liver injury by suppressing endoplasmic reticulum stress, oxidative stress and inflammation
inferred← citeshttps://doi.org/10.1016/j.sajb.2022.01.007openalex-snapshotAnalysis of phytochemical composition of a leaf extract of sacred fig (Ficus religiosa L.) by UPLC-QqQ-MS and assessment of its hepatocurative potential in mouse model
inferred← citeshttps://doi.org/10.1016/j.sjbs.2015.02.008openalex-snapshotAntioxidant, α-glucosidase inhibitory and anti-inflammatory effects of aerial parts extract from Korean crowberry (Empetrum nigrum var. japonicum)
inferred← citeshttps://doi.org/10.1021/acs.jafc.6b04805openalex-snapshotCapsaicin Inhibits Dimethylnitrosamine-Induced Hepatic Fibrosis by Inhibiting the TGF-β1/Smad Pathway via Peroxisome Proliferator-Activated Receptor Gamma Activation
inferred← citeshttps://doi.org/10.1038/s41598-018-37475-wopenalex-snapshotGenome-guided and mass spectrometry investigation of natural products produced by a potential new actinobacterial strain isolated from a mangrove ecosystem in Futian, Shenzhen, China
inferred← citeshttps://doi.org/10.1039/c3ob42010hopenalex-snapshotDesign, synthesis and evaluation of novel tacrine–rhein hybrids as multifunctional agents for the treatment of Alzheimer's disease
inferred← citeshttps://doi.org/10.1039/c4ay02506gopenalex-snapshotScreening and analyzing the potential bioactive components from rhubarb, using a multivariate data processing approach and ultra-high performance liquid chromatography coupled with time-of-flight mass spectrometry
inferred← citeshttps://doi.org/10.1039/c4ra08992hopenalex-snapshotUltra-high performance liquid chromatography coupled with time-of-flight mass spectrometry screening and analysis of potential bioactive compounds from traditional chinese medicine Kai-Xin-San, using a multivariate data processing approach and the MetaboLynx tool
inferred← citeshttps://doi.org/10.1039/c6ra19422bopenalex-snapshotUHPLC-FT-ICR-MS combined with serum pharmacochemistry for bioactive compounds discovery of Zhi-Zi-Da-Huang-decoction against alcohol-induced hepatotoxicity in rats
inferred← citeshttps://doi.org/10.1039/c8ra00522bopenalex-snapshotCelastrol delays hepatic steatosis and carcinogenesis in a rapid AKT/c-Met-transfected hepatocellular carcinoma model via suppressing fatty acid synthase expression and AKT/ERK phosphorylation
inferred← citeshttps://doi.org/10.1039/c9cc07573aopenalex-snapshotChemical modification of ovatodiolide revealed a promising amino-prodrug with improved pharmacokinetic profile
inferred← citeshttps://doi.org/10.1039/d1ra00962aopenalex-snapshotNew pentacyclic triterpenoids isolated from Leptopus chinensis and their hepatoprotective activities on tert -butyl hydroperoxide-induced oxidative injury
inferred← citeshttps://doi.org/10.1039/d2fo00507gopenalex-snapshot6′- O -Caffeoylarbutin from Que Zui tea ameliorates acetaminophen-induced liver injury via enhancing antioxidant ability and regulating the PI3K signaling pathway
inferred← citeshttps://doi.org/10.1039/d5ra01835hopenalex-snapshotDe novo drug design and biological evaluation of coumarin–pyrimidine co-drug derivatives as diabetic inhibitors: expanding a multi-algorithm approach with the integration of machine learning in pharmaceutical research
inferred← citeshttps://doi.org/10.1080/07391102.2022.2085804openalex-snapshotIdentification of phytochemicals from Eclipta alba and assess their potentiality against Hepatitis C virus envelope glycoprotein: virtual screening, docking, and molecular dynamics simulation study
inferred← citeshttps://doi.org/10.1080/2314808x.2022.2098461openalex-snapshotHepatoprotective potentials of methanolic extracts of Roselle and beetroots against carbon tetrachloride andEscherichia coliinduced stress in Wistar rats
inferred← citeshttps://doi.org/10.1093/bbb/zbad114openalex-snapshotIdentification and mechanistic investigation of ellagitannins from Osbeckia octandra that attenuate liver fibrosis via the TGF-β/SMAD signaling pathway
inferred← citeshttps://doi.org/10.1093/bbb/zbaf064openalex-snapshotEffects of combination of krill oil with curcumin and/or silymarin on mouse non-alcoholic fatty liver disease
inferred← citeshttps://doi.org/10.1111/jfbc.13259openalex-snapshotSimultaneous characterization and quantification of flavonoids in Morus australis root as potential hepatoprotective nutraceutical
inferred← citeshttps://doi.org/10.1155/2013/257909openalex-snapshotAdvancing Drug Discovery and Development from Active Constituents of Yinchenhao Tang, a Famous Traditional Chinese Medicine Formula
inferred← citeshttps://doi.org/10.1155/2019/5729263openalex-snapshotIdentification of Mitochondrial Ligands with Hepatoprotective Activity from Notopterygii Rhizoma et Radix Using Affinity Ultrafiltration/Liquid Chromatography/Mass Spectrometry
inferred← citeshttps://doi.org/10.1155/2020/1208726openalex-snapshotAmelioration by Idesia polycarpa Maxim. var. vestita Diels. of Oleic Acid-Induced Nonalcoholic Fatty Liver in HepG2 Cells through Antioxidant and Modulation of Lipid Metabolism
inferred← citeshttps://doi.org/10.1155/2020/7171498openalex-snapshotA Comprehensive Review of Natural Products against Liver Fibrosis: Flavonoids, Quinones, Lignans, Phenols, and Acids
inferred← citeshttps://doi.org/10.1155/2022/4929824openalex-snapshotPhytochemical Analysis and Antioxidant and Antidiabetic Activities of Extracts from Bergenia ciliata, Mimosa pudica, and Phyllanthus emblica
inferred← citeshttps://doi.org/10.1155/2023/4839124openalex-snapshotA Comprehensive Review on Extraction, Structure, Detection, Bioactivity, and Metabolism of Flavonoids from Sea Buckthorn (Hippophae rhamnoides L.)
inferred← citeshttps://doi.org/10.1186/s12906-016-1537-7openalex-snapshotHepatoprotective effect of the solvent extracts of Viola canescens Wall. ex. Roxb. against CCl4 induced toxicity through antioxidant and membrane stabilizing activity
inferred← citeshttps://doi.org/10.12816/0038260openalex-snapshotEFFECTS OF ROSEMARY EXTRACT SUPPLEMENTATION ON ETHANOL INDUCED LIVER INJURY IN ADULT MALE ALBINO RAT
inferred← citeshttps://doi.org/10.14719/pst.1691openalex-snapshotHepatoprotective potency of Lagenandra toxicaria and Ariopsis peltata against CCl4 induced liver fibrosis in Wistar rats
inferred← citeshttps://doi.org/10.14719/pst.2018.5.2.384openalex-snapshotGC-MS analysis of root methanolic extract of Gynochthodes ridsdalei Razafim. and B. Bremer, an endemic, endangered species of southern Western Ghats of India
inferred← citeshttps://doi.org/10.1515/jcim-2018-0159openalex-snapshotAssessment of compliance level of ICH guidelines for organic volatile impurities in common ayurvedic hepatic formulations
inferred← citeshttps://doi.org/10.15376/biores.14.3.6465-6484openalex-snapshotPreparation of porous composite bio-carriers from lignin-carbohydrate complexes and cellulose nanocrystals, and their application in the culture of human hepatocytes
inferred← citeshttps://doi.org/10.17169/refubium-10836openalex-snapshotBedeutung und mögliche therapeutische Nutzung von Komponenten der extrazellulären Matrix, KCa3.1-Ionenkanälen und Lindera obtusiloba bei Leberfibrose und dem hepatozellulären Karzinom
inferred← citeshttps://doi.org/10.18632/aging.205161openalex-snapshotHepatoprotective effect of syringin combined with costunolide against LPS-induced acute liver injury in L-02 cells via Rac1/AKT/NF-κB signaling pathway
inferred← citeshttps://doi.org/10.21203/rs.3.rs-5219178/v1openalex-snapshotAntioxidant, Antidiabetic, Analgesic, and Antibacterial Properties of Chrysopogon zizanioides Leaf Extract: An In Vivo, In Vitro, and In Silico Evaluation
inferred← citeshttps://doi.org/10.2139/ssrn.5002783openalex-snapshotHistopathological and Biochemical Effects of Methanol and Aqueous Extracts of the Leaf of Irvingia gabonensis (African Wild Mango) on the Liver of Albino Wistar Rat
inferred← citeshttps://doi.org/10.2147/dddt.s601517openalex-snapshotThe Natural Compound Cornuside Protects Against Acute Liver Failure Induced by Lipopolysaccharide and D-Galactosamine
inferred← citeshttps://doi.org/10.2147/jep.s258566openalex-snapshotIn vivo Hepatoprotective and in vitro Radical Scavenging Activities of Extracts of Rumex abyssinicus Jacq. Rhizome
inferred← citeshttps://doi.org/10.21608/esctj.2021.106959.1005openalex-snapshotAntioxidant Approach of Nigella Sativa, Vit C and Silymarin for amelioration of Azithromycin induced Hepatotoxicity: Histological, Immunohistochemical and Biochemical study
inferred← citeshttps://doi.org/10.21608/rpbs.2022.177461.1189openalex-snapshotProtective effect of curcumin on diclofenac sodium-induced hepatotoxicity in male albino rats: Evidence of its antioxidant and anti-inflammatory properties
inferred← citeshttps://doi.org/10.22159/ijcpr.2017.v9i3.19665openalex-snapshotGC-MS ANALYSIS OF METHANOLIC STEM EXTRACT OF GYNOCHTHODES RIDSDALEI, RAZAFIM AND B. BREMER, AN ENDEMIC, ENDANGERED MEDICINAL PLANT OF SOUTHERN WESTERN GHATS
inferred← citeshttps://doi.org/10.30867/action.v2i1.33openalex-snapshotAktifitas Hepatoprotektif Ekstrak Etanol Daun Sirsak (Annona Muricata L.) Terhadap Kerusakan Hati Tikus yang Diinduksi dengan Parasetamol
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