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New 1,3-thiazole derivatives and their biological and ultrastructural effects on Trypanosoma cruzi

https://doi.org/10.1016/j.ejmech.2016.05.050
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/clc.4960231205openalex-snapshot
Chagas' Heart Disease
inferredcites →https://doi.org/10.1002/cmdc.200700022openalex-snapshot
Synthesis, Cruzain Docking, and in vitro Studies of Aryl‐4‐Oxothiazolylhydrazones Against Trypanosoma cruzi
inferredcites →https://doi.org/10.1002/cmdc.201300354openalex-snapshot
Structural Design, Synthesis and Structure–Activity Relationships of Thiazolidinones with Enhanced Anti‐Trypanosoma cruzi Activity
inferredcites →https://doi.org/10.1002/jcc.20425openalex-snapshot
RM1: A reparameterization of AM1 for H, C, N, O, P, S, F, Cl, Br, and I
inferredcites →https://doi.org/10.1002/jcc.21256openalex-snapshot
AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility
inferredcites →https://doi.org/10.1007/978-3-319-13884-8_17openalex-snapshot
Chagas Disease (American Trypanosomiasis)
inferredcites →https://doi.org/10.1007/s00436-006-0326-5openalex-snapshot
Effect of oregano (Origanum vulgare L.) and thyme (Thymus vulgaris L.) essential oils on Trypanosoma cruzi (Protozoa: Kinetoplastida) growth and ultrastructure
inferredcites →https://doi.org/10.1016/j.bcp.2004.04.019openalex-snapshot
Phenyl substitution of furamidine markedly potentiates its anti-parasitic activity against Trypanosoma cruzi and Leishmania amazonensis
inferredcites →https://doi.org/10.1016/j.bmc.2006.01.034openalex-snapshot
Synthesis, docking, and in vitro activity of thiosemicarbazones, aminoacyl-thiosemicarbazides and acyl-thiazolidones against Trypanosoma cruzi
inferredcites →https://doi.org/10.1016/j.bmc.2008.11.065openalex-snapshot
Synthesis, trypanocidal activity and docking studies of novel quinoxaline-N-acylhydrazones, designed as cruzain inhibitors candidates
inferredcites →https://doi.org/10.1016/j.bmc.2009.07.004openalex-snapshot
Novel 1,2,3-thiadiazole derivatives as HIV-1 NNRTIs with improved potency: Synthesis and preliminary SAR studies
inferredcites →https://doi.org/10.1016/j.bmc.2009.07.068openalex-snapshot
Design, synthesis and cruzain docking of 3-(4-substituted-aryl)-1,2,4-oxadiazole-N-acylhydrazones as anti-Trypanosoma cruzi agents
inferredcites →https://doi.org/10.1016/j.bmc.2010.09.056openalex-snapshot
Studies toward the structural optimization of novel thiazolylhydrazone-based potent antitrypanosomal agents
inferredcites →https://doi.org/10.1016/j.bmc.2012.08.047openalex-snapshot
Optimization of anti-Trypanosoma cruzi oxadiazoles leads to identification of compounds with efficacy in infected mice
inferredcites →https://doi.org/10.1016/j.bmcl.2004.10.023openalex-snapshot
Discovery of potent thiosemicarbazone inhibitors of rhodesain and cruzain
inferredcites →https://doi.org/10.1016/j.bmcl.2006.05.041openalex-snapshot
Design, synthesis, and biochemical evaluation of novel cruzain inhibitors with potential application in the treatment of Chagas’ disease
inferredcites →https://doi.org/10.1016/j.ejmech.2014.08.012openalex-snapshot
2-Pyridyl thiazoles as novel anti-Trypanosoma cruzi agents: Structural design, synthesis and pharmacological evaluation
inferredcites →https://doi.org/10.1016/j.ejmech.2015.04.015openalex-snapshot
Recent applications of 1,3-thiazole core structure in the identification of new lead compounds and drug discovery
inferredcites →https://doi.org/10.1016/j.ejmech.2015.06.048openalex-snapshot
Synthesis and structure–activity relationship study of a new series of antiparasitic aryloxyl thiosemicarbazones inhibiting Trypanosoma cruzi cruzain
inferredcites →https://doi.org/10.1016/j.ijantimicag.2003.07.020openalex-snapshot
Selective in vitro effects of the farnesyl pyrophosphate synthase inhibitor risedronate on Trypanosoma cruzi
inferredcites →https://doi.org/10.1016/j.ijantimicag.2003.12.009openalex-snapshot
Effects of squalene synthase inhibitors on the growth and ultrastructure of Trypanosoma cruzi
inferredcites →https://doi.org/10.1016/j.ijpddr.2011.12.002openalex-snapshot
Recent developments in sterol 14-demethylase inhibitors for Chagas disease
inferredcites →https://doi.org/10.1016/j.jmgm.2011.01.004openalex-snapshot
BINANA: A novel algorithm for ligand-binding characterization
inferredcites →https://doi.org/10.1016/j.molbiopara.2012.04.012openalex-snapshot
Leishmania (L.) amazonensis peptidase activities inside the living cells and in their lysates
inferredcites →https://doi.org/10.1016/s0960-894x(03)00756-xopenalex-snapshot
Synthesis and evaluation of isatins and thiosemicarbazone derivatives against cruzain, falcipain-2 and rhodesain
inferredcites →https://doi.org/10.1016/s1074-5521(00)00018-1openalex-snapshot
Aryl ureas represent a new class of anti-trypanosomal agents
inferredcites →https://doi.org/10.1016/s1369-5274(98)80065-9openalex-snapshot
Roles of cysteine proteinases of trypanosomes and Leishmania in host-parasite interactions
inferredcites →https://doi.org/10.1021/ja710254mopenalex-snapshot
Identification of a New Class of Nonpeptidic Inhibitors of Cruzain
inferredcites →https://doi.org/10.1021/jm010459jopenalex-snapshot
Synthesis and Structure−Activity Relationship Study of Potent Trypanocidal Thio Semicarbazone Inhibitors of the Trypanosomal Cysteine Protease Cruzain
inferredcites →https://doi.org/10.1021/jm030549jopenalex-snapshot
Synthesis and Structure−Activity Relationships of Parasiticidal Thiosemicarbazone Cysteine Protease Inhibitors against Plasmodium falciparum , Trypanosoma brucei , and Trypanosoma cruzi
inferredcites →https://doi.org/10.1021/jm301518vopenalex-snapshot
Structural Investigation of Anti-Trypanosoma cruzi 2-Iminothiazolidin-4-ones Allows the Identification of Agents with Efficacy in Infected Mice
inferredcites →https://doi.org/10.1021/jm801585uopenalex-snapshot
2-Acetylpyridine Thiosemicarbazones are Potent Iron Chelators and Antiproliferative Agents: Redox Activity, Iron Complexation and Characterization of their Antitumor Activity
inferredcites →https://doi.org/10.1021/jm9009229openalex-snapshot
Divergent Modes of Enzyme Inhibition in a Homologous Structure−Activity Series
inferredcites →https://doi.org/10.1021/jm901633vopenalex-snapshot
Nonpeptidic Tetrafluorophenoxymethyl Ketone Cruzain Inhibitors as Promising New Leads for Chagas Disease Chemotherapy
inferredcites →https://doi.org/10.1097/crd.0b013e31821950f9openalex-snapshot
Myotonic Dystrophies and the Heart
inferredcites →https://doi.org/10.1097/crd.0b013e31823efde2openalex-snapshot
Chagas Heart Disease
inferredcites →https://doi.org/10.1111/j.1550-7408.2001.tb00195.xopenalex-snapshot
The Sterol Composition of Trypanosoma cruzi Changes After Growth in Different Culture Media and Results in Different Sensitivity to Digitonin‐Permeabilization
inferredcites →https://doi.org/10.1128/aac.00537-10openalex-snapshot
Tolerance of Benznidazole in Treatment of Chagas' Disease in Adults
inferredcites →https://doi.org/10.1128/aac.04601-14openalex-snapshot
Synthesis of a Sugar-Based Thiosemicarbazone Series and Structure-Activity Relationship versus the Parasite Cysteine Proteases Rhodesain, Cruzain, and Schistosoma mansoni Cathepsin B1
inferredcites →https://doi.org/10.1371/journal.pntd.0001861openalex-snapshot
Is Chagas Disease Really the “New HIV/AIDS of the Americas”?
inferredcites →https://doi.org/10.1371/journal.pntd.0002370openalex-snapshot
Non-peptidic Cruzain Inhibitors with Trypanocidal Activity Discovered by Virtual Screening and In Vitro Assay
inferredcites →https://doi.org/10.1590/s0074-02762006000200013openalex-snapshot
The effect of Bulgarian propolis against Trypanosoma cruzi and during its interaction with host cells
inferredcites →https://doi.org/10.1590/s0074-02762009000900006openalex-snapshot
Epidemiology, control and surveillance of Chagas disease: 100 years after its discovery
inferredcites →https://doi.org/10.2174/138945009787581140openalex-snapshot
Approaches for the Development of New Anti-Trypanosoma cruzi Agents
inferredcites →https://doi.org/10.3390/molecules18066366openalex-snapshot
Design, Synthesis and Trypanocidal Evaluation of Novel 1,2,4-Triazoles-3-thiones Derived from Natural Piperine

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4746016openalex-extracted
Chagas Disease: History, Pathophysiology and Therapeutic Treatment
inferred← citeshttps://doi.org/10.1002/cmdc.202000331openalex-snapshot
Dual Parasiticidal Activities of Phthalimides: Synthesis and Biological Profile against Trypanosoma cruzi and Plasmodium falciparum
inferred← citeshttps://doi.org/10.1002/jhet.3496openalex-snapshot
Design, Synthesis, and Anticancer Activity of New Oxadiazolyl‐Linked and Thiazolyl‐Linked Benzimidazole Arylidines, Thioglycoside, and Acyclic Analogs
inferred← citeshttps://doi.org/10.1007/s00436-020-06931-wopenalex-snapshot
Antitrichomonal activity and docking analysis of thiazole derivatives as TvMP50 protease inhibitors
inferred← citeshttps://doi.org/10.1016/j.bmc.2021.116577openalex-snapshot
Examination of multiple Trypanosoma cruzi targets in a new drug discovery approach for Chagas disease
inferred← citeshttps://doi.org/10.1016/j.cbi.2021.109514openalex-snapshot
Structural design, synthesis and anti-Trypanosoma cruzi profile of the second generation of 4-thiazolidinones chlorine derivatives
inferred← citeshttps://doi.org/10.1016/j.cbi.2021.109561openalex-snapshot
Structural improvement of new thiazolyl-isatin derivatives produces potent and selective trypanocidal and leishmanicidal compounds
inferred← citeshttps://doi.org/10.1016/j.cbi.2021.109597openalex-snapshot
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Synthesis, acetylcholinesterase and butyrylcholinesterase inhibitory potential and molecular docking study of thiazole bearing thiourea analogues
inferred← citeshttps://doi.org/10.1016/j.ejmech.2017.01.040openalex-snapshot
Synthesis and trypanocidal activity of a library of 4-substituted 2-(1H-pyrrolo[3,2-c]pyridin-2-yl)propan-2-ols
inferred← citeshttps://doi.org/10.1016/j.ejmech.2017.02.026openalex-snapshot
Desing and synthesis of potent anti-Trypanosoma cruzi agents new thiazoles derivatives which induce apoptotic parasite death
inferred← citeshttps://doi.org/10.1016/j.ejmech.2017.05.011openalex-snapshot
Rhodium-catalyzed C-H bond activation for the synthesis of quinonoid compounds: Significant Anti-Trypanosoma cruzi activities and electrochemical studies of functionalized quinones
inferred← citeshttps://doi.org/10.1016/j.ejmech.2017.09.047openalex-snapshot
Structural design, synthesis and pharmacological evaluation of thiazoles against Trypanosoma cruzi
inferred← citeshttps://doi.org/10.1016/j.ejmech.2017.12.040openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.ejmech.2018.03.083openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.ejmech.2018.08.079openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.ejmech.2018.11.013openalex-snapshot
Thiazole, thio and semicarbazone derivatives against tropical infective diseases: Chagas disease, human African trypanosomiasis (HAT), leishmaniasis, and malaria
inferred← citeshttps://doi.org/10.1016/j.ejmech.2019.03.024openalex-snapshot
Multi-target compounds acting in cancer progression: Focus on thiosemicarbazone, thiazole and thiazolidinone analogues
inferred← citeshttps://doi.org/10.1016/j.ejmech.2019.04.052openalex-snapshot
Thiazolidinone/thiazole based hybrids – New class of antitrypanosomal agents
inferred← citeshttps://doi.org/10.1016/j.ejmech.2022.115002openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.ejmech.2023.115310openalex-snapshot
Structural design, synthesis, and anti-Trypanosomatidae profile of new Pyridyl-thiazolidinones
inferred← citeshttps://doi.org/10.1016/j.ejmech.2023.115508openalex-snapshot
1,3-Thiazole derivatives as privileged structures for anti-Trypanosoma cruzi activity: Rational design, synthesis, in silico and in vitro studies
inferred← citeshttps://doi.org/10.1016/j.ejmech.2024.117191openalex-snapshot
New series of 3-pyridyl-1,3-thiazoles: In vitro and in vivo anti-Trypanosomatidae profile, in vitro and in silico mechanism of action approach
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Schiff bases of 4-Phenyl-2-Aminothiazoles as hits to new antischistosomals: Synthesis, in vitro, in vivo and in silico studies
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inferred← citeshttps://doi.org/10.1016/j.jfluchem.2022.110024openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.jmgm.2020.107821openalex-snapshot
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