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Nanoformulations for dimethyl fumarate: Physicochemical characterization and in vitro / in vivo behavior

https://doi.org/10.1016/j.ejpb.2017.04.011
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/s00415-013-6968-1openalex-snapshot
Clinical efficacy of BG-12 (dimethyl fumarate) in patients with relapsing–remitting multiple sclerosis: subgroup analyses of the CONFIRM study
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Management of dysphagia in patients affected by multiple sclerosis: state of the art
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Effect of Surface Charge of Immortalized Mouse Cerebral Endothelial Cell Monolayer on Transport of Charged Solutes
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Integrin β4 Signaling Promotes Mammary Tumor Cell Adhesion to Brain Microvascular Endothelium by Inducing ErbB2-Mediated Secretion of VEGF
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Quantification of Malignant Breast Cancer Cell MDA-MB-231 Transmigration Across Brain and Lung Microvascular Endothelium
inferredcites →https://doi.org/10.1007/s11095-013-1122-4openalex-snapshot
Targeted Delivery of Nano-Therapeutics for Major Disorders of the Central Nervous System
inferredcites →https://doi.org/10.1007/s11910-013-0394-8openalex-snapshot
Dimethyl Fumarate for Treatment of Multiple Sclerosis: Mechanism of Action, Effectiveness, and Side Effects
inferredcites →https://doi.org/10.1016/b978-0-444-52001-2.00008-xopenalex-snapshot
The experimental autoimmune encephalomyelitis (EAE) model of MS
inferredcites →https://doi.org/10.1016/j.addr.2003.12.002openalex-snapshot
Solid lipid nanoparticles for parenteral drug delivery
inferredcites →https://doi.org/10.1016/j.addr.2012.09.015openalex-snapshot
Nanoparticulate systems for brain delivery of drugs
inferredcites →https://doi.org/10.1016/j.clim.2011.02.017openalex-snapshot
Fumaric acid and its esters: An emerging treatment for multiple sclerosis with antioxidative mechanism of action
inferredcites →https://doi.org/10.1016/j.ejpb.2008.09.003openalex-snapshot
Lipid nanoparticles for parenteral delivery of actives
inferredcites →https://doi.org/10.1016/j.ejpb.2011.10.015openalex-snapshot
Nanoparticulate lipid dispersions for bromocriptine delivery: Characterization and in vivo study
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Effect of nanostructured lipid vehicles on percutaneous absorption of curcumin
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Biodistribution of nanostructured lipid carriers: A tomographic study
inferredcites →https://doi.org/10.1016/j.ejpb.2016.03.005openalex-snapshot
Encapsulation of cannabinoid drugs in nanostructured lipid carriers
inferredcites →https://doi.org/10.1016/j.ijpharm.2007.06.023openalex-snapshot
Influence of surface charge and inner composition of porous nanoparticles to cross blood–brain barrier in vitro
inferredcites →https://doi.org/10.1016/j.ijpharm.2008.09.004openalex-snapshot
Mathematical modeling of drug delivery
inferredcites →https://doi.org/10.1016/j.jneuroim.2013.02.013openalex-snapshot
Nasal administration of drugs as a new non-invasive strategy for efficient treatment of multiple sclerosis
inferredcites →https://doi.org/10.1016/j.msec.2013.08.017openalex-snapshot
Curcumin containing monoolein aqueous dispersions: A preformulative study
inferredcites →https://doi.org/10.1016/j.msec.2014.12.012openalex-snapshot
Cannabinoid antagonist in nanostructured lipid carriers (NLCs): design, characterization and in vivo study
inferredcites →https://doi.org/10.1016/s0009-2509(00)00458-9openalex-snapshot
Crystallization behaviour of fats and lipids — a review
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Evaluation of Effect of Charge and Lipid Coating on Ability of 60-nm Nanoparticles to Cross an In Vitro Model of the Blood-Brain Barrier
inferredcites →https://doi.org/10.1016/s0140-6736(08)61620-7openalex-snapshot
Multiple sclerosis
inferredcites →https://doi.org/10.1016/s0169-409x(00)00122-8openalex-snapshot
Nanoparticulate systems for brain delivery of drugs
inferredcites →https://doi.org/10.1023/a:1010067107182openalex-snapshot
Dynamic Light Scattering Measurement of Nanometer Particles in Liquids
inferredcites →https://doi.org/10.1080/10611860400015936openalex-snapshot
Nanoparticle Surface Charges Alter Blood–Brain Barrier Integrity and Permeability
inferredcites →https://doi.org/10.1080/10611860500071292openalex-snapshot
Polysorbate-stabilized solid lipid nanoparticles as colloidal carriers for intravenous targeting of drugs to the brain: Comparison of plasma protein adsorption patterns
inferredcites →https://doi.org/10.1080/10611860500411043openalex-snapshot
Body distribution of polysorbate‐80 and doxorubicin-loaded [14C]poly(butyl cyanoacrylate) nanoparticles after i.v. administration in rats
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Differential Opening of the Brain Endothelial Following Neutralization of the Endothelial Luminal Anionic Charge In Vitro
inferredcites →https://doi.org/10.1111/j.1748-1716.1985.tb07746.xopenalex-snapshot
Endothelial negative surface charge areas and blood‐brain barrier function
inferredcites →https://doi.org/10.1115/1.4003309openalex-snapshot
An Electrodiffusion Model for the Blood-Brain Barrier Permeability to Charged Molecules
inferredcites →https://doi.org/10.1177/1756285614564152openalex-snapshot
Dimethyl fumarate in the treatment of relapsing–remitting multiple sclerosis: an overview
inferredcites →https://doi.org/10.1177/35.11.3655325openalex-snapshot
Demonstration of anionic sites on the luminal and abluminal fronts of endothelial cells with poly-L-lysine-gold complex.
inferredcites →https://doi.org/10.14227/dt190212p6openalex-snapshot
In Vitro Release Testing of PLGA Microspheres with Franz Diffusion Cells
inferredcites →https://doi.org/10.1517/13543776.2015.1043267openalex-snapshot
Novel diagnostic tools and solutions for multiple sclerosis treatment: a patent review (2009 – 2014)
inferredcites →https://doi.org/10.1517/13543776.8.1.1openalex-snapshot
Therapeutic approaches to respiratory diseases other than asthma: trends from the patent literature 1993 - 1997
inferredcites →https://doi.org/10.1517/17425247.2012.673278openalex-snapshot
Lipid nanoparticles: state of the art, new preparation methods and challenges in drug delivery
inferredcites →https://doi.org/10.1602/neurorx.2.1.108openalex-snapshot
Drug transport to brain with targeted nanoparticles
inferredcites →https://doi.org/10.18433/j3nc79openalex-snapshot
Intranasal Drug Delivery: How, Why and What for?
inferredcites →https://doi.org/10.2147/ijn.s16570openalex-snapshot
Enhanced brain targeting of temozolomide in polysorbate-80 coated polybutylcyanoacrylate nanoparticles
inferredcites →https://doi.org/10.2174/0929867321666140716095644openalex-snapshot
Nanomedicine Based Nanoparticles for Neurological Disorders
inferredcites →https://doi.org/10.2174/1573411011309010037openalex-snapshot
Analysis of the Drug Release Profiles from Formulations Based on Micro and Nano Systems
inferredcites →https://doi.org/10.2174/157341113804486400openalex-snapshot
Analysis of the Drug Release Profiles from Formulations Based on Micro and Nano Systems
inferredcites →https://doi.org/10.2217/nnm.11.79openalex-snapshot
In VivoBiodistribution of Nanoparticles
inferredcites →https://doi.org/10.4137/dti.s12519openalex-snapshot
P-glycoprotein Inhibition for Optimal Drug Delivery
inferredcites →https://doi.org/10.4172/2157-7439.1000256openalex-snapshot
Production, Physico-Chemical Characterization and Biodistribution Studies of Lipid Nanoparticles

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Taking Advantages of Blood–Brain Barrier to Optimize Delivery of Drugs in Central Neurological Conditions
inferred← citeshttps://doi.org/10.1007/s11033-023-08968-3openalex-snapshot
Current non-invasive strategies for brain drug delivery: overcoming blood–brain barrier transport
inferred← citeshttps://doi.org/10.1007/s13346-025-01912-xopenalex-snapshot
Carvacrol-based nanoemulsions loaded with dimethyl fumarate intended for nose to brain delivery for treatment of multiple sclerosis
inferred← citeshttps://doi.org/10.1007/s40263-022-00930-4openalex-snapshot
Using the Intranasal Route to Administer Drugs to Treat Neurological and Psychiatric Illnesses: Rationale, Successes, and Future Needs
inferred← citeshttps://doi.org/10.1016/b978-0-443-19143-5.00003-7openalex-snapshot
Phytoconstituents-based nanoformulations for neurodegenerative disorders
inferred← citeshttps://doi.org/10.1016/bs.irn.2023.05.014openalex-snapshot
Nose-to-brain drug delivery for the treatment of CNS disease: New development and strategies
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Armamentarium of nanoscaled lipid drug delivery systems customized for oral administration: In silico docking patronage, absorption phenomenon, preclinical status, clinical status and future prospects
inferred← citeshttps://doi.org/10.1016/j.colsurfb.2021.112091openalex-snapshot
Switch off inflammation in spleen cells with CD40-targeted PLGA nanoparticles containing dimethyl fumarate
inferred← citeshttps://doi.org/10.1016/j.dib.2017.08.033openalex-snapshot
Data on scaling up and in vivo human study of progesterone lipid nanoparticles
inferred← citeshttps://doi.org/10.1016/j.ejpb.2017.07.015openalex-snapshot
Progesterone lipid nanoparticles: Scaling up and in vivo human study
inferred← citeshttps://doi.org/10.1016/j.ejpb.2020.01.005openalex-snapshot
Current insights on lipid nanocarrier-assisted drug delivery in the treatment of neurodegenerative diseases
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2024.134908openalex-snapshot
A thermosensitive chitosan hydrogel: An attempt for the nasal delivery of dimethyl fumarate
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2023.122936openalex-snapshot
Nose to brain delivery of ibudilast micelles for treatment of multiple sclerosis in an experimental autoimmune encephalomyelitis animal model
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2024.124216openalex-snapshot
Design and development of a chitosan-based nasal powder of dimethyl fumarate-cyclodextrin binary systems aimed at nose-to-brain administration. A stability study
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2024.124686openalex-snapshot
The piper at the gates of brain: A systematic review of surface modification strategies on lipid nanoparticles to overcome the Blood-Brain-Barrier
inferred← citeshttps://doi.org/10.1016/j.jconrel.2022.02.009openalex-snapshot
Recent advancements in nanoparticle-mediated approaches for restoration of multiple sclerosis
inferred← citeshttps://doi.org/10.1016/j.jddst.2021.102645openalex-snapshot
Chitosan-alginate core-shell-corona shaped nanoparticles of dimethyl fumarate in orodispersible film to improve bioavailability in treatment of multiple sclerosis: Preparation, characterization and biodistribution in rats
inferred← citeshttps://doi.org/10.1016/j.jddst.2024.105530openalex-snapshot
Polydopamine coated surfactin micelles for brain delivery of ibudilast in multiple sclerosis: Design, optimization, in vitro and in vivo evaluation
inferred← citeshttps://doi.org/10.1021/acs.molpharmaceut.1c00892openalex-snapshot
Targeted Delivery Platforms for the Treatment of Multiple Sclerosis
inferred← citeshttps://doi.org/10.1038/s41573-021-00139-yopenalex-snapshot
Strategies for delivering therapeutics across the blood–brain barrier
inferred← citeshttps://doi.org/10.1080/10837450.2021.1950186openalex-snapshot
Nanotechnologies for intranasal drug delivery: an update of literature
inferred← citeshttps://doi.org/10.1080/17425247.2018.1429401openalex-snapshot
Lipid nanoparticles for intranasal administration: application to nose-to-brain delivery
inferred← citeshttps://doi.org/10.1080/17435889.2024.2374700openalex-snapshot
Decitabine enclosed biotin-zein conjugated nanoparticles: synthesis, characterization, in vitro and in vivo evaluation
inferred← citeshttps://doi.org/10.17352/2455-3492.000070openalex-snapshot
Dimethyl Fumarate Sterically Stabilized Solid Lipid Nanoparticles. Physicochemical properties and in vitro drug release
inferred← citeshttps://doi.org/10.2147/ijn.s236968openalex-snapshot
A Correlative Imaging Study of in vivo and ex vivo Biodistribution of Solid Lipid Nanoparticles
inferred← citeshttps://doi.org/10.2147/ijn.s347187openalex-snapshot
Nanoparticles in Combating Neuronal Dysregulated Signaling Pathways: Recent Approaches to the Nanoformulations of Phytochemicals and Synthetic Drugs Against Neurodegenerative Diseases
inferred← citeshttps://doi.org/10.2147/ijn.s481917openalex-snapshot
Hyaluronic Acid-Based Hybrid Nanoparticles as Promising Carriers for the Intranasal Administration of Dimethyl Fumarate
inferred← citeshttps://doi.org/10.2174/0115672018330624241125060045openalex-snapshot
Brain Targeting Using Nanocolloids for the Management of Multiple Sclerosis
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Nanomodulation of Macrophages in Multiple Sclerosis
inferred← citeshttps://doi.org/10.3390/ijms24044133openalex-snapshot
Ethosomal Gel for Topical Administration of Dimethyl Fumarate in the Treatment of HSV-1 Infections
inferred← citeshttps://doi.org/10.3390/ijms262411827openalex-snapshot
Diroximel Fumarate-Loaded Solid Lipid Nanoparticles (DRF-SLNs) as Potential Carriers for the Treatment of Multiple Sclerosis: Preformulation Study
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New and Old Horizons for an Ancient Drug: Pharmacokinetics, Pharmacodynamics, and Clinical Perspectives of Dimethyl Fumarate
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