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Emodin ameliorates lipopolysaccharide-induced mastitis in mice by inhibiting activation of NF-κB and MAPKs signal pathways
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/jnr.10548openalex-snapshot
Increased nuclear factor‐κB p65 immunoreactivity following retinal ischemia and reperfusion injury in mice
inferredcites →https://doi.org/10.1007/978-3-642-80186-0_7openalex-snapshot
Cytokines as Mediators in the Pathogenesis of Septic Shock
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Protective effects of emodin combined with danshensu on experimental severe acute pancreatitis
inferredcites →https://doi.org/10.1007/s00011-012-0545-4openalex-snapshot
Salidroside attenuates inflammatory responses by suppressing nuclear factor-κB and mitogen activated protein kinases activation in lipopolysaccharide-induced mastitis in mice
inferredcites →https://doi.org/10.1007/s10911-011-9235-zopenalex-snapshot
Mastitis Therapy and Antimicrobial Susceptibility: a Multispecies Review with a Focus on Antibiotic Treatment of Mastitis in Dairy Cattle
inferredcites →https://doi.org/10.1016/0016-5085(84)90202-6openalex-snapshot
Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity
inferredcites →https://doi.org/10.1016/j.cdp.2008.12.003openalex-snapshot
Effects of emodin on the gene expression profiling of human breast carcinoma cells
inferredcites →https://doi.org/10.1016/j.cellsig.2004.08.005openalex-snapshot
Involvement of PKCα/β in TLR4 and TLR2 dependent activation of NF-κB
inferredcites →https://doi.org/10.1016/j.ijporl.2007.09.005openalex-snapshot
Proinflammatory and immunoregulatory cytokines in the middle ear effusions
inferredcites →https://doi.org/10.1016/j.intimp.2011.10.018openalex-snapshot
Ruscogenin inhibits lipopolysaccharide-induced acute lung injury in mice: Involvement of tissue factor, inducible NO synthase and nuclear factor (NF)-κB
inferredcites →https://doi.org/10.1016/j.jinf.2006.06.010openalex-snapshot
Innate immune response of bovine mammary gland to pathogenic bacteria responsible for mastitis
inferredcites →https://doi.org/10.1016/j.micinf.2004.11.008openalex-snapshot
The pathogenesis and control of Staphylococcus aureus-induced mastitis: study models in the mouse
inferredcites →https://doi.org/10.1016/j.rvsc.2006.05.006openalex-snapshot
Effect of intramammary infusion of bacterial lipopolysaccharide on experimentally induced Staphylococcus aureus intramammary infection
inferredcites →https://doi.org/10.1016/s0065-2776(08)60742-7openalex-snapshot
NF-κB as a Frequent Target for Immunosuppressive and Anti-Inflammatory Molecules**This article was accepted for publication on 27 September 1996.
inferredcites →https://doi.org/10.1016/s0898-6568(97)00042-9openalex-snapshot
Stress-activated Protein Kinases: Activation, Regulation and Function
inferredcites →https://doi.org/10.1016/s0925-4439(96)00048-8openalex-snapshot
Initiation of acute phase response and synthesis of cytokines
inferredcites →https://doi.org/10.1016/s1357-4310(99)01544-0openalex-snapshot
p38 MAPK signalling cascades in inflammatory disease
inferredcites →https://doi.org/10.1023/a:1020563913045openalex-snapshot
New Insights into the Biology of the Acute Phase Response
inferredcites →https://doi.org/10.1038/sj.onc.1201998openalex-snapshot
Emodin (3-methyl-1,6,8-trihydroxyanthraquinone) inhibits TNF-induced NF-κB activation, IκB degradation, and expression of cell surface adhesion proteins in human vascular endothelial cells
inferredcites →https://doi.org/10.1051/vetres:2005051openalex-snapshot
Characterization of cytokine expression in milk somatic cells during intramammary infections withEscherichia coliorStaphylococcus aureusby real-time PCR
inferredcites →https://doi.org/10.1053/tvjl.2002.0724openalex-snapshot
Bovine Mastitis: An Evolving Disease
inferredcites →https://doi.org/10.1056/nejm199704103361506openalex-snapshot
Nuclear Factor-κB — A Pivotal Transcription Factor in Chronic Inflammatory Diseases
inferredcites →https://doi.org/10.1080/00480169.2011.547165openalex-snapshot
Economic aspects of mastitis: New developments
inferredcites →https://doi.org/10.1096/fasebj.4.11.2199284openalex-snapshot
Biology of multifunctional cytokines: IL 6 and related molecules (IL 1 and TNF)
inferredcites →https://doi.org/10.1111/j.1476-5381.2010.00993.xopenalex-snapshot
Emodin suppresses lipopolysaccharide‐induced pro‐inflammatory responses and NF‐κB activation by disrupting lipid rafts in CD14‐negative endothelial cells
inferredcites →https://doi.org/10.1128/iai.64.3.1011-1015.1996openalex-snapshot
Low-dose lipopolysaccharide (LPS) pretreatment of mouse macrophages modulates LPS-dependent interleukin-6 production in vitro
inferredcites →https://doi.org/10.1146/annurev.immunol.21.120601.141126openalex-snapshot
Toll-Like Receptors
inferredcites →https://doi.org/10.1155/2007/29638openalex-snapshot
The Effect of Emodin-Assisted Early Enteral Nutrition on Severe Acute Pancreatitis and Secondary Hepatic Injury
inferredcites →https://doi.org/10.3168/jds.s0022-0302(03)73832-6openalex-snapshot
Elevated Milk Soluble CD14 in Bovine Mammary Glands Challenged with Escherichia coli Lipopolysaccharide
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Emodin - A natural anthraquinone derivative with diverse pharmacological activities
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Emodin: A Review of its Pharmacology, Toxicity and Pharmacokinetics
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Aloe‐emodin: A review of its pharmacology, toxicity, and pharmacokinetics
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Emodin and Its Role in Chronic Diseases
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Thymol Inhibits LPS-Stimulated Inflammatory Response via Down-Regulation of NF-κB and MAPK Signaling Pathways in Mouse Mammary Epithelial Cells
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Magnolol Inhibits the Inflammatory Response in Mouse Mammary Epithelial Cells and a Mouse Mastitis Model
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RETRACTED ARTICLE: Inhibition of Lipopolysaccharide (LPS)-Induced Inflammatory Responses by Selenium in Bovine Mammary Epithelial Cells in Primary Culture
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Bergenin Plays an Anti-Inflammatory Role via the Modulation of MAPK and NF-κB Signaling Pathways in a Mouse Model of LPS-Induced Mastitis
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Protective Effects of Kaempferol on Lipopolysaccharide-Induced Mastitis in Mice
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Dietary Selenium Deficiency Exacerbates Lipopolysaccharide-Induced Inflammatory Response in Mouse Mastitis Models
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Oxymatrine Lightened the Inflammatory Response of LPS-Induced Mastitis in Mice Through Affecting NF-κB and MAPKs Signaling Pathways
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Indirubin Inhibits LPS-Induced Inflammation via TLR4 Abrogation Mediated by the NF-kB and MAPK Signaling Pathways
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Inhibitory Effects of Emodin, Thymol, and Astragalin on Leptospira interrogans-Induced Inflammatory Response in the Uterine and Endometrium Epithelial Cells of Mice
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Anti-inflammatory Effects of Rosmarinic Acid in Lipopolysaccharide-Induced Mastitis in Mice
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Phytochemical analysis and enhanced production of alkaloids in non-dormant corm-derived callus of Gloriosa superba (L.) using plant growth regulators and abiotic elicitors
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Rhein protects 5/6 nephrectomized rat against renal injury by reducing inflammation via NF-κB signaling
inferred← citeshttps://doi.org/10.1007/s12011-020-02106-xopenalex-snapshot
Germanium Reduces Inflammatory Damage in Mammary Glands During Lipopolysaccharide-Induced Mastitis in Mice
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The Prevention Effect of Lactobacillus plantarum 17–5 on Escherichia coli-Induced Mastitis in Mice
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Prediction of key regulators and downstream targets of E. coli induced mastitis
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Downregulation of tumor necrosis factor and other proinflammatory biomarkers by polyphenols
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N-acetyl cysteine inhibits lipopolysaccharide-mediated induction of interleukin-6 synthesis in MC3T3-E1 cells through the NF-kB signaling pathway
inferred← citeshttps://doi.org/10.1016/j.bbrc.2018.08.198openalex-snapshot
Shikonin exerts anti-inflammatory effects in LPS-induced mastitis by inhibiting NF-κB signaling pathway
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Anti-inflammatory effects of Shufengjiedu capsule for upper respiratory infection via the ERK pathway
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The activity of Hou-Po-Da-Huang-Tang is improved through intestinal bacterial metabolism and Hou-Po-Da-Huang-Tang selectively stimulate the growth of intestinal bacteria associated with health
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The inhibition effect of caffeic acid on NOX/ROS-dependent macrophages M1-like polarization contributes to relieve the LPS-induced mice mastitis
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Effective degradation of anthraquinones in Folium Sennae with Monascus fermentation for toxicity reduce and efficacy enhancement
inferred← citeshttps://doi.org/10.1016/j.intimp.2013.07.010openalex-snapshot
Astragalin suppresses inflammatory responses via down-regulation of NF-κB signaling pathway in lipopolysaccharide-induced mastitis in a murine model
inferred← citeshttps://doi.org/10.1016/j.intimp.2014.08.018openalex-snapshot
Emodin ameliorated lipopolysaccharide-induced fulminant hepatic failure by blockade of TLR4/MD2 complex expression in D-galactosamine-sensitized mice
inferred← citeshttps://doi.org/10.1016/j.intimp.2015.03.025openalex-snapshot
Epigallocatechin-3-gallate attenuates lipopolysaccharide-induced mastitis in rats via suppressing MAPK mediated inflammatory responses and oxidative stress
inferred← citeshttps://doi.org/10.1016/j.intimp.2015.11.011openalex-snapshot
Protective effects of melatonin on lipopolysaccharide-induced mastitis in mice
inferred← citeshttps://doi.org/10.1016/j.intimp.2016.02.023openalex-snapshot
Emodin attenuates TNF-α-induced apoptosis and autophagy in mouse C2C12 myoblasts though the phosphorylation of Akt
inferred← citeshttps://doi.org/10.1016/j.intimp.2016.03.026openalex-snapshot
Sophocarpine displays anti-inflammatory effect via inhibiting TLR4 and TLR4 downstream pathways on LPS-induced mastitis in the mammary gland of mice
inferred← citeshttps://doi.org/10.1016/j.intimp.2020.106804openalex-snapshot
Piperine protects LPS-induced mastitis by inhibiting inflammatory response
inferred← citeshttps://doi.org/10.1016/j.intimp.2020.107020openalex-snapshot
Emodin improves alveolar hypercoagulation and inhibits pulmonary inflammation in LPS-provoked ARDS in mice via NF-κB inactivation
inferred← citeshttps://doi.org/10.1016/j.intimp.2022.108940openalex-snapshot
Hydrogen helps to ameliorate Staphylococcus aureus-induced mastitis in mice
inferred← citeshttps://doi.org/10.1016/j.jep.2014.11.009openalex-snapshot
Traditional usages, botany, phytochemistry, pharmacology and toxicology of Polygonum multiflorum Thunb.: A review
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Taohe Chengqi Decoction ameliorates APID-related local uterine inflammatory injury through modulation of inflammation, oxidative stress, and JNK/p38 MAPK–NF-κB-related signaling
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Emodin alleviates lung injury via the miR-217-5p/Sirt1 axis in rats with severe acute pancreatitis
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Systemic TNF-α blockade attenuates anxiety and depressive-like behaviors in db/db mice through downregulation of inflammatory signaling in peripheral immune cells
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Exploring characteristics of value-added production of anthraquinones in rhubarb via fermentation: Compartmental modelling and molecular docking analysis
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Machine learning-assisted optimized production of quorum quenching anthraquinones in rhubarb
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Dietary phytochemicals for possible preventive and therapeutic option of uterine fibroids: Signaling pathways as target
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Emodin mitigates diesel exhaust particles-induced increase in airway resistance, inflammation and oxidative stress in mice
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Alpha-linolenic acid based nano-suspension protect against lipopolysaccharides induced mastitis by inhibiting NFκBp65, HIF-1α, and mitochondria-mediated apoptotic pathway in albino Wistar rats
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Synthesis and antibacterial activity of emodin and its derivatives against methicillin-resistant Staphylococcus aureus
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Emodin: A metabolite that exhibits anti-neoplastic activities by modulating multiple oncogenic targets
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Oleuropein ameliorated lung ischemia-reperfusion injury by inhibiting TLR4 signaling cascade in alveolar macrophages
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Emodin attenuates high glucose-induced TGF-β1 and fibronectin expression in mesangial cells through inhibition of NF-κB pathway
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Emodin ameliorates matrix degradation and apoptosis in nucleus pulposus cells and attenuates intervertebral disc degeneration through LRP1 in vitro and in vivo
inferred← citeshttps://doi.org/10.1016/s0254-6272(15)30159-xopenalex-snapshot
Effect of emodin on Aquaporin 5 expression in rats with sepsis-induced acute lung injury
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Identification of active compound combination contributing to anti-inflammatory activity of Xiao-Cheng-Qi Decoction via human intestinal bacterial metabolism
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(-)-Epigallocatechin-3-gallate and hydroxytyrosol improved antioxidative and anti-inflammatory responses in bovine mammary epithelial cells
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Antidepressant-like Effect of Merazin Hydrate Depends on NO/ERK by Suppressing Its Downstream NF-κB or Nonactivating CREB/BDNF in Mouse Hippocampus
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UPLC/MS/MS-Based Metabolomics Study of the Hepatotoxicity and Nephrotoxicity in Rats Induced by Polygonum multiflorum Thunb.
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Imidazoanthraquinone Derivatives for the Chromofluorogenic Sensing of Basic Anions and Trivalent Metal Cations
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The hydroxy-analogue of selenomethionine alleviated lipopolysaccharide-induced inflammatory responses is associated with recover expression of several selenoprotein encoding genes in the spleens of Kunming mice
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Fumaric acid protects rats from ciprofloxacin-provoked depression through modulating TLR4, Nrf-2, and p190-rho GTP
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Emodin up‐regulates glucose metabolism, decreases lipolysis, and attenuates inflammation in vitro大黄素在体内上调糖代谢、减少脂解和抑制炎症反应
inferred← citeshttps://doi.org/10.1111/bph.13976openalex-snapshot
Butyrate protects against disruption of the blood‐milk barrier and moderates inflammatory responses in a model of mastitis induced by lipopolysaccharide
inferred← citeshttps://doi.org/10.1111/jfpp.13160openalex-snapshot
Main anthraquinone components in Aloe vera and their inhibitory effects on the formation of advanced glycation end-products
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Research Progress in Ulcerative Colitis: The Role of Traditional Chinese Medicine on Gut Microbiota and Signaling Pathways
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Anti-Inflammatory and Antinociceptive Activities of Anthraquinone-2-Carboxylic Acid
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Indirubin Treatment of Lipopolysaccharide-Induced Mastitis in a Mouse Model and Activity in Mouse Mammary Epithelial Cells
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TLR4-NF-κB Signal Involved in Depressive-Like Behaviors and Cytokine Expression of Frontal Cortex and Hippocampus in Stressed C57BL/6 and ob/ob Mice
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Effective Treatment of Bovine Mastitis with Intramammary Infusion of Angelica dahurica and Rheum officinale Extracts
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Diesel Exhaust Particles Induce Impairment of Vascular and Cardiac Homeostasis in Mice: Ameliorative Effect of Emodin
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Effects of aqueous extracts of Taraxacum Officinale on expression of tumor necrosis factor-alpha and intracellular adhesion molecule 1 in LPS-stimulated RMMVECs
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Cyanidin-3-O-β-glucoside inhibits lipopolysaccharide-induced inflammatory response in mouse mastitis model
inferred← citeshttps://doi.org/10.12677/acm.2024.1482213openalex-snapshot
Research Progress on the Treatment of Primary Hypertension with Tianma Gouteng Decoction
inferred← citeshttps://doi.org/10.1517/17460441.2013.795539openalex-snapshot
Anti-allergic drug discovery in China for eczema: current methods and future strategies
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Ginseng polysaccharides promote gut microbiota mediated deoxycholic acid to alleviate LPS-induced mastitis by regulating TGR5-cAMP-PKA-NF-κB/NLRP3 pathway
inferred← citeshttps://doi.org/10.2147/ijn.s589401openalex-snapshot
Emodin-Based Drug Delivery Systems: Therapeutic Applications in Inflammatory Diseases
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Xuanbi Yuyang Decoction Ameliorates DSS-Induced Colitis by Inhibiting Pyroptosis via Blocking of IL-17 Pathway Activation
inferred← citeshttps://doi.org/10.2174/1389450124666230818092506openalex-snapshot
A Comprehensive Review on Therapeutic Potential of a Natural Anthraquinone Derivative Emodin in Brain-related Disorders
inferred← citeshttps://doi.org/10.3109/09553002.2014.884292openalex-snapshot
Emodin, an anthraquinone derivative, protects against gamma radiation-induced toxicity by inhibiting DNA damage and oxidative stress
inferred← citeshttps://doi.org/10.32718/ujvas4-1.05openalex-snapshot
Use of plant-derived drugs in the prevention and treatment of dairy cow mastitis
inferred← citeshttps://doi.org/10.3389/fcimb.2021.603309openalex-snapshot
Targeting Host Cellular Factors as a Strategy of Therapeutic Intervention for Herpesvirus Infections
inferred← citeshttps://doi.org/10.3389/fphar.2016.00448openalex-snapshot
San-Huang-Xie-Xin-Tang Constituents Exert Drug-Drug Interaction of Mutual Reinforcement at Both Pharmacodynamics and Pharmacokinetic Level: A Review
inferred← citeshttps://doi.org/10.3389/fphar.2019.00522openalex-snapshot
Emodin Rescues Intrahepatic Cholestasis via Stimulating FXR/BSEP Pathway in Promoting the Canalicular Export of Accumulated Bile
inferred← citeshttps://doi.org/10.3389/fphar.2021.638993openalex-snapshot
Pharmacokinetics of Anthraquinones from Medicinal Plants
inferred← citeshttps://doi.org/10.3389/fphar.2025.1520281openalex-snapshot
Emodin mitigates rheumatoid arthritis through direct binding to TNF-α
inferred← citeshttps://doi.org/10.3389/fvets.2022.978453openalex-snapshot
Emodin from Aloe inhibits Swine acute diarrhea syndrome coronavirus in cell culture
inferred← citeshttps://doi.org/10.3390/ani10091625openalex-snapshot
Overview of Research Development on the Role of NF-κB Signaling in Mastitis
inferred← citeshttps://doi.org/10.3390/antibiotics14101000openalex-snapshot
Decoding Mastitis in Small Rodent Pets: Pathophysiology, Antimicrobial Resistance Profiles, and Future Directions in Treatment Strategies
inferred← citeshttps://doi.org/10.3390/ijms151119355openalex-snapshot
Emodin Ameliorates LPS-Induced Acute Lung Injury, Involving the Inactivation of NF-κB in Mice
inferred← citeshttps://doi.org/10.3390/ijms19061770openalex-snapshot
Farrerol Relieve Lipopolysaccharide (LPS)-Induced Mastitis by Inhibiting AKT/NF-κB p65, ERK1/2 and P38 Signaling Pathway
inferred← citeshttps://doi.org/10.3390/molecules19011258openalex-snapshot
Inhibition of Epstein-Barr Virus Lytic Cycle by an Ethyl Acetate Subfraction Separated from Polygonum cuspidatum Root and Its Major Component, Emodin
inferred← citeshttps://doi.org/10.3390/molecules22101754openalex-snapshot
Emodin Inhibition of Influenza A Virus Replication and Influenza Viral Pneumonia via the Nrf2, TLR4, p38/JNK and NF-kappaB Pathways
inferred← citeshttps://doi.org/10.3390/molecules24050997openalex-snapshot
Novel Therapeutics for Epstein–Barr Virus
inferred← citeshttps://doi.org/10.3390/v13071243openalex-snapshot
Emodin from Aloe Inhibits Porcine Reproductive and Respiratory Syndrome Virus via Toll-Like Receptor 3 Activation
inferred← citeshttps://doi.org/10.3892/mmr.2019.9846openalex-snapshot
Sodium houttuyfonate inhibits LPS‑induced mastitis in mice via the NF‑κB signalling pathway
inferred← citeshttps://doi.org/10.3923/ijp.2017.175.182openalex-snapshot
Liver Protective and Reactive Oxygen Species Scavenging Effects of Emodin in Lipopolysaccharide/Bacillus Calmette Guerin-injured Mice by Optical Molecular Imaging
inferred← citeshttps://doi.org/10.4103/pm.pm_207_21openalex-snapshot
Rhei rhizoma and citri pericarpium mixture regulates oxidative stress and tight junction proteins on acute reflux esophagitis
inferred← citeshttps://doi.org/10.5114/ceji.2016.63807openalex-snapshot
EGb761 attenuates depressive-like behaviours induced by long-term light deprivation in C57BL/6J mice through inhibition of NF-κB-IL-6 signalling pathway
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