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Effects of P-glycoprotein on the intestine and blood-brain barrier transport of YZG-331, a promising sedative-hypnotic compound
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/0471141755.ph0713s58openalex-snapshot
Assessment of P‐Glycoprotein Substrate and Inhibition Potential of Test Compounds in MDR1‐Transfected MDCK Cells
inferredcites →https://doi.org/10.1002/ijc.29566openalex-snapshot
ABCB 1 and ABCG 2 restrict the brain penetration of a panel of novel EZH 2‐Inhibitors
inferredcites →https://doi.org/10.1002/ptr.5040openalex-snapshot
Evaluation of First-Pass Cytochrome P4503A (CYP3A) and P-glycoprotein Activities Using Felodipine and Hesperetin in Combination in Wistar Rats and Everted Rat Gut Sacs in Vitro
inferredcites →https://doi.org/10.1007/s002130050961openalex-snapshot
Residual effects of zolpidem 10 mg and zopiclone 7.5 mg versus flunitrazepam 1 mg and placebo on driving performance and ocular saccades
inferredcites →https://doi.org/10.1007/s00894-012-1416-1openalex-snapshot
FDA approved drugs complexed to their targets: evaluating pose prediction accuracy of docking protocols
inferredcites →https://doi.org/10.1016/j.bcp.2015.01.008openalex-snapshot
P-glycoprotein interactions of novel psychoactive substances – Stimulation of ATP consumption and transport across Caco-2 monolayers
inferredcites →https://doi.org/10.1016/j.ejphar.2012.06.032openalex-snapshot
Influence of P-glycoprotein on brucine transport at the in vitro blood–brain barrier
inferredcites →https://doi.org/10.1016/j.ejps.2006.06.004openalex-snapshot
Site of drug absorption after oral administration: Assessment of membrane permeability and luminal concentration of drugs in each segment of gastrointestinal tract
inferredcites →https://doi.org/10.1016/j.ejps.2013.08.010openalex-snapshot
Enhancement effect of P-gp inhibitors on the intestinal absorption and antiproliferative activity of bestatin
inferredcites →https://doi.org/10.1016/j.ijpharm.2004.10.007openalex-snapshot
Evaluation of the MDR-MDCK cell line as a permeability screen for the blood–brain barrier
inferredcites →https://doi.org/10.1016/j.jep.2011.08.064openalex-snapshot
The neuroprotective effects of an extract of Gastrodia elata
inferredcites →https://doi.org/10.1016/j.pbb.2012.06.002openalex-snapshot
NHBA isolated from Gastrodia elata exerts sedative and hypnotic effects in sodium pentobarbital-treated mice
inferredcites →https://doi.org/10.1016/j.taap.2013.12.015openalex-snapshot
Inhibitory effects of herbal constituents on P-glycoprotein in vitro and in vivo: Herb–drug interactions mediated via P-gp
inferredcites →https://doi.org/10.1016/s0169-409x(02)00171-0openalex-snapshot
Drug–drug interaction mediated by inhibition and induction of P-glycoprotein
inferredcites →https://doi.org/10.1021/js980233copenalex-snapshot
Enhancement of paracellular drug transport with highly quaternized N‐trimethyl chitosan chloride in neutral environments: In vitro evaluation in intestinal epithelial cells (Caco‐2)
inferredcites →https://doi.org/10.1021/mp050095hopenalex-snapshot
Scientific Perspectives on Drug Transporters and Their Role in Drug Interactions
inferredcites →https://doi.org/10.1021/mp900132eopenalex-snapshot
Scientific and Regulatory Perspectives on Metabolizing Enzyme−Transporter Interplay and Its Role in Drug Interactions: Challenges in Predicting Drug Interactions
inferredcites →https://doi.org/10.1021/np0605182openalex-snapshot
Neuroprotective Principles from Gastrodia elata
inferredcites →https://doi.org/10.1023/a:1026183200740openalex-snapshot
P-Glycoprotein Increases from Proximal to Distal Regions of Human Small Intestine
inferredcites →https://doi.org/10.1038/nrd3955openalex-snapshot
Adenosine receptors as drug targets — what are the challenges?
inferredcites →https://doi.org/10.1053/smrv.2002.0186openalex-snapshot
Epidemiology of insomnia: what we know and what we still need to learn
inferredcites →https://doi.org/10.1055/s-2007-967137openalex-snapshot
Transport of Decursin and Decursinol Angelate across Caco-2 and MDR-MDCK Cell Monolayers: In vitro Models for Intestinal and Blood-Brain Barrier Permeability
inferredcites →https://doi.org/10.1080/00498250110060969openalex-snapshot
Role of transport proteins in drug absorption, distribution and excretion
inferredcites →https://doi.org/10.1111/bcpt.12084openalex-snapshot
Role of P‐glycoprotein in the Uptake/Efflux Transport of Oral Vitamin K Antagonists and Rivaroxaban through the Caco‐2 Cell Model
inferredcites →https://doi.org/10.1111/j.1365-2125.1986.tb05229.xopenalex-snapshot
Zopiclone produces effects on human performance similar to flurazepam, lormetazepam and triazolam.
inferredcites →https://doi.org/10.1124/dmd.107.015321openalex-snapshot
Permeability, Transport, and Metabolism of Solutes in Caco-2 Cell Monolayers: A Theoretical Study
inferredcites →https://doi.org/10.1124/dmd.107.017434openalex-snapshot
In Vitro P-glycoprotein Assays to Predict the in Vivo Interactions of P-glycoprotein with Drugs in the Central Nervous System
inferredcites →https://doi.org/10.1124/jpet.109.156943openalex-snapshot
Functional Characterization of Multidrug Resistance-Associated Protein 3 (Mrp3/Abcc3) in the Basolateral Efflux of Glucuronide Conjugates in the Mouse Small Intestine
inferredcites →https://doi.org/10.1124/jpet.113.208959openalex-snapshot
Pharmacokinetic Assessment of Efflux Transport in Sunitinib Distribution to the Brain
inferredcites →https://doi.org/10.1124/pr.113.007518openalex-snapshot
Transporters and Drug-Drug Interactions: Important Determinants of Drug Disposition and Effects
inferredcites →https://doi.org/10.1126/science.1168750openalex-snapshot
Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
inferredcites →https://doi.org/10.1146/annurev.pharmtox.44.101802.121444openalex-snapshot
EVALUATION OF DRUG-DRUG INTERACTION IN THE HEPATOBILIARY AND RENAL TRANSPORT OF DRUGS
inferredcites →https://doi.org/10.1152/ajpheart.1984.247.3.h484openalex-snapshot
An in situ brain perfusion technique to study cerebrovascular transport in the rat
inferredcites →https://doi.org/10.1371/journal.pone.0025815openalex-snapshot
Predicting P-Glycoprotein-Mediated Drug Transport Based On Support Vector Machine and Three-Dimensional Crystal Structure of P-glycoprotein
inferredcites →https://doi.org/10.1371/journal.pone.0067060openalex-snapshot
Anticonvulsant Activity of B2, an Adenosine Analog, on Chemical Convulsant-Induced Seizures
inferredcites →https://doi.org/10.2133/dmpk.dmpk-11-rg-142openalex-snapshot
Role of P-Glycoprotein in Intestinal Absorption of FB2, a Promising Abl/Src Dual Tyrosine Kinase Inhibitor
inferredcites →https://doi.org/10.2165/00003088-200342010-00003openalex-snapshot
Role of P-Glycoprotein in Pharmacokinetics
inferredcites →https://doi.org/10.2174/1389200217666160111124139openalex-snapshot
Application of Model-Based Approaches to Evaluate Hepatic Transporter-Mediated Drug Clearance: In vitro, In vivo, and In vitro-In vivo Extrapolation
inferredcites →https://doi.org/10.2174/156802611795347654openalex-snapshot
The Role of Adenosine in the Regulation of Sleep
inferredcites →https://doi.org/10.5665/sleep.3410openalex-snapshot
National Use of Prescription Medications for Insomnia: NHANES 1999-2010
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4020822openalex-extracted
The Mechanism Study of YZG-331 on Sedative and Hypnotic Effect
inferred← citeshttps://doi.org/10.1007/s10439-018-02124-wopenalex-snapshot
In Vitro Models for Studying Transport Across Epithelial Tissue Barriers
inferred← citeshttps://doi.org/10.1016/j.apsb.2026.07.025openalex-snapshot
Neuroprotection by YZG-331 in postoperative cognitive dysfunction via Mg2+-dependent blockade of NMDA receptors
inferred← citeshttps://doi.org/10.1016/j.bbr.2022.113885openalex-snapshot
The mechanism study of YZG-331 on sedative and hypnotic effects
inferred← citeshttps://doi.org/10.1016/j.drudis.2019.02.007openalex-snapshot
Neuropharmacokinetics: a bridging tool between CNS drug development and therapeutic outcome
inferred← citeshttps://doi.org/10.1016/j.foodchem.2025.144914openalex-snapshot
Enhancement in the intestinal absorption of ginsenoside Re by ginseng polysaccharides and its mechanisms
inferred← citeshttps://doi.org/10.1039/c7ra02968copenalex-snapshot
Organic anion transporters 1 (OAT1) and OAT3 meditated the protective effect of rhein on methotrexate-induced nephrotoxicity
inferred← citeshttps://doi.org/10.2139/ssrn.5163049openalex-snapshot
Intestinal Absorption Enhancement of Ginseng Polysaccharides on Ginsenoside Re and its Mechanisms
inferred← citeshttps://doi.org/10.3389/fphar.2017.00527openalex-snapshot
Interspecies Variation of In Vitro Stability and Metabolic Diversity of YZG-331, a Promising Sedative-Hypnotic Compound
inferred← citeshttps://doi.org/10.3389/fphar.2021.796745openalex-snapshot
Involvement of P-gp on Reversing Multidrug Resistance Effects of 23-Hydroxybetulinic Acid on Chemotherapeutic Agents
inferred← citeshttps://doi.org/10.3390/molecules22081246openalex-snapshot
Effects of P-Glycoprotein on the Transport of DL0410, a Potential Multifunctional Anti-Alzheimer Agent
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