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Toll-like receptor 4-mediated ROS signaling pathway involved in Ganoderma atrum polysaccharide-induced tumor necrosis factor-α secretion during macrophage activation
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/j.1460-2075.1993.tb05850.xopenalex-snapshot
H2O2 and antioxidants have opposite effects on activation of NF‐kappa B and AP‐1 in intact cells: AP‐1 as secondary antioxidant‐responsive factor.
inferredcites →https://doi.org/10.1002/jcb.22526openalex-snapshot
Ganoderma atrum polysaccharide protects cardiomyocytes against anoxia/reoxygenation‐induced oxidative stress by mitochondrial pathway
inferredcites →https://doi.org/10.1002/jcb.22993openalex-snapshot
Ganoderma atrum polysaccharide induces anti‐tumor activity via the mitochondrial apoptotic pathway related to activation of host immune response
inferredcites →https://doi.org/10.1002/ptr.4698openalex-snapshot
Macrophage Immunomodulatory Activity of a Purified Polysaccharide Isolated from Ganoderma atrum
inferredcites →https://doi.org/10.1006/abbi.1997.0487openalex-snapshot
Role of Protein Kinase C in Basal and Hydrogen Peroxide-Stimulated NF-κB Activation in the Murine Macrophage J774A.1 Cell Line
inferredcites →https://doi.org/10.1007/s00018-008-8552-xopenalex-snapshot
Rac1 GTPase: A “Rac” of All Trades
inferredcites →https://doi.org/10.1016/0003-2697(83)90590-0openalex-snapshot
Preparation and properties of fluorescent polysaccharides
inferredcites →https://doi.org/10.1016/j.bbrc.2004.08.069openalex-snapshot
Immune receptors for polysaccharides from Ganoderma lucidum
inferredcites →https://doi.org/10.1016/j.carbpol.2012.01.061openalex-snapshot
Structural characterisation of a novel bioactive polysaccharide from Ganoderma atrum
inferredcites →https://doi.org/10.1016/j.cellimm.2010.07.002openalex-snapshot
Polysaccharide purified from Polyporus umbellatus (Per) Fr induces the activation and maturation of murine bone-derived dendritic cells via toll-like receptor 4
inferredcites →https://doi.org/10.1016/j.fct.2010.04.036openalex-snapshot
Cordlan polysaccharide isolated from mushroom Cordyceps militaris induces dendritic cell maturation through toll-like receptor 4 signalings
inferredcites →https://doi.org/10.1016/j.fct.2012.05.051openalex-snapshot
Activation of macrophages by polysaccharide isolated from Paecilomyces cicadae through toll-like receptor 4
inferredcites →https://doi.org/10.1016/j.foodchem.2007.08.021openalex-snapshot
Purification, composition analysis and antioxidant activity of a polysaccharide from the fruiting bodies of Ganoderma atrum
inferredcites →https://doi.org/10.1016/j.foodchem.2012.08.090openalex-snapshot
Immunomodulatory effect of Ganoderma atrum polysaccharide on CT26 tumor-bearing mice
inferredcites →https://doi.org/10.1016/j.intimp.2012.09.005openalex-snapshot
Polysaccharide from Ganoderma atrum induces tumor necrosis factor-α secretion via phosphoinositide 3-kinase/Akt, mitogen-activated protein kinase and nuclear factor-κB signaling pathways in RAW264.7 cells
inferredcites →https://doi.org/10.1016/j.jep.2010.06.028openalex-snapshot
TLR4-mediated activation of macrophages by the polysaccharide fraction from Polyporus umbellatus(pers.) Fries
inferredcites →https://doi.org/10.1016/j.jfoodeng.2006.10.018openalex-snapshot
Microwave-assisted extraction used for the isolation of total triterpenoid saponins from Ganoderma atrum
inferredcites →https://doi.org/10.1016/j.lfs.2009.09.001openalex-snapshot
The protective effect of Ganoderma atrum polysaccharide against anoxia/reoxygenation injury in neonatal rat cardiomyocytes
inferredcites →https://doi.org/10.1016/j.phytochem.2006.07.004openalex-snapshot
Ganoderma – A therapeutic fungal biofactory
inferredcites →https://doi.org/10.1016/s0952-7915(99)00045-xopenalex-snapshot
Toll signaling pathways in the innate immune response
inferredcites →https://doi.org/10.1016/s0952-7915(99)00046-1openalex-snapshot
Tlr4: central component of the sole mammalian LPS sensor
inferredcites →https://doi.org/10.1016/s0955-0674(96)80060-3openalex-snapshot
Phosphoinositide kinases
inferredcites →https://doi.org/10.1016/s0955-0674(98)80147-6openalex-snapshot
Oxygen radicals and signaling
inferredcites →https://doi.org/10.1016/s0962-8924(00)88960-6openalex-snapshot
Regulation of the phagocyte respiratory burst by small GTP-binding proteins
inferredcites →https://doi.org/10.1016/s0966-842x(00)01845-xopenalex-snapshot
The Toll receptor family and microbial recognition
inferredcites →https://doi.org/10.1016/s1286-4579(00)00299-9openalex-snapshot
CR3: a general purpose adhesion-recognition receptor essential for innate immunity
inferredcites →https://doi.org/10.1021/jf1049497openalex-snapshot
Enhancement of Cyclophosphamide-Induced Antitumor Effect by a Novel Polysaccharide fromGanoderma atrumin Sarcoma 180-Bearing Mice
inferredcites →https://doi.org/10.1021/jf4004225openalex-snapshot
Polysaccharide from Ganoderma atrum Evokes Antitumor Activity via Toll-like Receptor 4-Mediated NF-κB and Mitogen-Activated Protein Kinase Signaling Pathways
inferredcites →https://doi.org/10.1038/35100529openalex-snapshot
Toll-like receptors and innate immunity
inferredcites →https://doi.org/10.1038/90609openalex-snapshot
Toll-like receptors: critical proteins linking innate and acquired immunity
inferredcites →https://doi.org/10.1038/emm.1999.9openalex-snapshot
Redox signaling: hydrogen peroxide as intracellular messenger
inferredcites →https://doi.org/10.1038/nm1388openalex-snapshot
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
inferredcites →https://doi.org/10.1038/nri2038openalex-snapshot
Cooperation of Toll-like receptor signals in innate immune defence
inferredcites →https://doi.org/10.1074/jbc.274.32.22699openalex-snapshot
Reactive Oxygen Species Mediate the Activation of Akt/Protein Kinase B by Angiotensin II in Vascular Smooth Muscle Cells
inferredcites →https://doi.org/10.1074/jbc.m111.222091openalex-snapshot
Structure and Immunological Characterization of the Capsular Polysaccharide of a Pyrogenic Liver Abscess Caused by Klebsiella pneumoniae
inferredcites →https://doi.org/10.1089/ars.2006.8.1775openalex-snapshot
Reactive Oxygen Species-Induced Activation of the MAP Kinase Signaling Pathways
inferredcites →https://doi.org/10.1126/science.1085536openalex-snapshot
Toll-Like Receptor Signaling Pathways
inferredcites →https://doi.org/10.1146/annurev.immunol.18.1.621openalex-snapshot
Phosphorylation Meets Ubiquitination: The Control of NF-κB Activity
inferredcites →https://doi.org/10.1146/annurev.iy.12.040194.001041openalex-snapshot
Function and Activation of NF-Kappa B in the Immune System
inferredcites →https://doi.org/10.1152/ajplung.2000.279.6.l1005openalex-snapshot
Reactive oxygen species in cell signaling
inferredcites →https://doi.org/10.1172/jci949openalex-snapshot
Neutrophils exposed to bacterial lipopolysaccharide upregulate NADPH oxidase assembly.
inferredcites →https://doi.org/10.1189/jlb.0405181openalex-snapshot
Cationic liposomes induce apoptosis through p38 MAP kinase–caspase-8–Bid pathway in macrophage-like RAW264.7 cells
inferredcites →https://doi.org/10.1189/jlb.69.1.3openalex-snapshot
MAP kinase activation in macrophages
inferredcites →https://doi.org/10.2174/138161206778743538openalex-snapshot
Recognition of Fungal Pathogens by Toll-Like Receptors
inferredcites →https://doi.org/10.3109/10715769209079515openalex-snapshot
Nuclear Factor Kb: An Oxidative Stress-Responsive Transcription Factor of Eukaryotic Cells (A Review)
inferredcites →https://doi.org/10.4049/jimmunol.159.5.2418openalex-snapshot
Hydrogen peroxide-mediated transcriptional induction of macrophage colony-stimulating factor by TGF-beta1
inferredcites →https://doi.org/10.4049/jimmunol.172.4.2522openalex-snapshot
Involvement of Reactive Oxygen Species in Toll-Like Receptor 4-Dependent Activation of NF-κB
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Structure Analysis and Anti‐Inflammatory Effect of a Polysaccharide from Hippocampus mohnikei
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The Influence of Polysaccharides‐Based Material on Macrophage Phenotypes
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Chemical Components and Cancer Immunotherapy of Ganoderma
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Yam glycoprotein mediated the immunomodulation of macrophages by targeting TLR4
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Structure–function insights of natural Ganoderma polysaccharides: advances in biosynthesis and functional food applications
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Mitochondrial dysfunction and underlying molecular mechanisms in acrylamide-induced toxicity
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Structural analysis and immunomodulatory activity of a homopolysaccharide isolated from Parabacteroides distasonis
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Identification of pivotal components on the antioxidant activity of polysaccharide extract from Ganoderma atrum
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Bioactive effect of sulphated polysaccharides derived from orange-footed sea cucumber ( Cucumaria frondosa) toward THP-1 macrophages
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Polysaccharides as antioxidants and prooxidants in managing the double-edged sword of reactive oxygen species
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Traditional Chinese medicine polysaccharide in nano-drug delivery systems: Current progress and future perspectives
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Immune-enhancing activities of chondroitin sulfate in murine macrophage RAW 264.7 cells
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Innate immune receptors co-recognition of polysaccharides initiates multi-pathway synergistic immune response
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Structure–function insights into galactans of Endocladia muricata: Physicochemical properties and immunomodulatory activity
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Pulsed electric field (PEF) activates immune activity in RAW 264.7 macrophages by altering pine nut peptide-TLR4 binding sites
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Protective effect of Ganoderma atrum polysaccharide on acrolein-induced macrophage injury via autophagy-dependent apoptosis pathway
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Investigation on activation in RAW264.7 macrophage cells and protection in cyclophosphamide-treated mice of Pseudostellaria heterophylla protein hydrolysate
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Immunomodulatory activities of polysaccharides from Ganoderma on immune effector cells
inferred← citeshttps://doi.org/10.1016/j.foodchem.2021.131586openalex-snapshot
Interaction between polysaccharides and toll-like receptor 4: Primary structural role, immune balance perspective, and 3D interaction model hypothesis
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Mechanisms of RAW264.7 macrophages immunomodulation mediated by polysaccharide from mung bean skin based on RNA-seq analysis
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Effect of ultrasonic modification on the protective activity of Flammulina velutipes polysaccharide to prevent ethanol-induced injury on GES-1 cells
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The effects of dietary oxidized konjac glucomannan and its acidolysis products on the immune response, expression of immune related genes and disease resistance of Schizothorax prenanti
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Immune responses to Aeromonas hydrophila infection in Schizothorax prenanti fed with oxidized konjac glucomannan and its acidolysis products
inferred← citeshttps://doi.org/10.1016/j.fsi.2019.03.008openalex-snapshot
Polysaccharide fraction from the Indian mistletoe, Dendrophthoe falcata (L.f.) Ettingsh enhances innate immunity and disease resistance in Oreochromis niloticus (Linn.)
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e25607openalex-snapshot
Ganoderma lucidum: Insight into antimicrobial and antioxidant properties with development of secondary metabolites
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2015.04.077openalex-snapshot
Structural elucidation and biological studies of a novel exopolysaccaride from Klebsiella pneumoniae PB12
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2016.06.024openalex-snapshot
Mechanism of the immunostimulatory activity by a polysaccharide from Dictyophora indusiata
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2018.08.147openalex-snapshot
Polysaccharide isolated from Sarcodon aspratus induces RAW264.7 activity via TLR4-mediated NF-κB and MAPK signaling pathways
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2019.01.022openalex-snapshot
Mechanism of the anti-inflammatory activity by a polysaccharide from Dictyophora indusiata in lipopolysaccharide-stimulated macrophages
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2019.11.064openalex-snapshot
Separation, purification, structural analysis and immune-enhancing activity of sulfated polysaccharide isolated from sea cucumber viscera
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Molecular mechanisms associated with macrophage activation by Rhizoma Atractylodis Macrocephalae polysaccharides
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Molecular mechanisms underlying macrophage immunomodulatory activity of Rubus chingii Hu polysaccharides
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Immunomodulation effect of polysaccharides from liquid fermentation of Monascus purpureus 40269 via membrane TLR-4 to activate the MAPK and NF-κB signaling pathways
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2023.125199openalex-snapshot
A review of Ganoderma lucidum polysaccharides: Health benefit, structure–activity relationship, modification, and nanoparticle encapsulation
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Sulfate glycosaminoglycan from swim bladder exerts immunomodulatory potential on macrophages via toll-like receptor 4 mediated NF-κB signaling pathways
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Purification, structural characterization and immunomodulatory activity of a polysaccharide isolated from Scutellaria baicalensis stem-leaf
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Immunomodulation of exopolysaccharide produced by Lacticaseibacillus rhamnosus ZFM216 in cyclophosphamide-induced immunosuppressed mice by modulating gut microbiota
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Comparative study on extraction procedures for polysaccharides from safflower post-extraction residue: Structural characterization and bioactivity evaluation
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Effects of selenizing angelica polysaccharide and selenizing garlic polysaccharide on immune function of murine peritoneal macrophage
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Barbaloin protects against lipopolysaccharide (LPS)-induced acute lung injury by inhibiting the ROS-mediated PI3K/AKT/NF-κB pathway
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Molecular mechanism underlying chemoprotective effects of Ganoderma atrum polysaccharide in cyclophosphamide-induced immunosuppressed mice
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Structural characterization and macrophage immunomodulatory activity of a polysaccharide isolated from Gracilaria lemaneiformis
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Immunomodulatory effect of Ganoderma atrum polysaccharides on Th17/Treg balance
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Biodistribution and immunomodulatory activities of a proteoglycan isolated from Ganoderma lucidum
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Identification of bioactive polysaccharide from Pseudostellaria heterophylla with its anti-inflammatory effects
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Macrophage immunomodulatory effects of low molecular weight peptides from Mytilus coruscus via NF-κB/MAPK signaling pathways
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Ganoderma atrum polysaccharide interferes with TLR4 against PD-1 inhibitors-induced carditis via NF-κB-NLRP3 pathway driven by IRF1/VEGFA/14–3-3γ axis in Lewis lung carcinoma mice
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Signaling Pathway Involved in the Immunomodulatory Effect of Ganoderma atrum Polysaccharide in Spleen Lymphocytes
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Characterization and Immunomodulatory Activity of a Novel Peptide, ECFSTA, from Wheat Germ Globulin
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Toll-like Receptor 4 Mediates the Antitumor Host Response Induced by Ganoderma atrum Polysaccharide
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High leukocyte mitochondrial DNA content contributes to poor prognosis in glioma patients through its immunosuppressive effect
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Kallistatin protects against sepsis-related acute lung injury via inhibiting inflammation and apoptosis
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The structure of mushroom polysaccharides and their beneficial role in health
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Review on cell models to evaluate the potential antioxidant activity of polysaccharides
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Structure characterization of a novel polysaccharide from Hericium erinaceus fruiting bodies and its immunomodulatory activities
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The protective effects of the Ganoderma atrum polysaccharide against acrylamide-induced inflammation and oxidative damage in rats
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Role of genistein on the yield, structure and immunomodulatory activity of Monascus exopolysaccharides
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An immune-stimulating proteoglycan from the medicinal mushroom Huaier up-regulates NF-κB and MAPK signaling via Toll-like receptor 4
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Exploring the health benefits of Ganoderma : bioactive compounds and mechanisms of action; immunomodulatory, and anti-tumour activities
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Structural characterization, immune activity, and action mechanisms of fractionated polysaccharides from Athyrium multidentatum (Doll.) Ching
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Transcriptomic analysis reveals the key regulators and molecular mechanisms underlying myometrial activation during equine placentitis†
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Crude polysaccharide from the milky mushroom, Calocybe indica, modulates innate immunity of macrophage cells by triggering MyD88-dependent TLR4/NF-κB pathway
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Immunomodulatory effects of extract of Ganoderma lucidum basidiocarps cultivated on alternative substrate
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Functional crosstalk between non‐canonical caspase‐11 and canonical NLRP3 inflammasomes during infection‐mediated inflammation
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Non-specific immunity and disease resistance are enhanced by the polysaccharide fraction of a marine chlorophycean macroalga inOreochromis niloticus(Linnaeus, 1758)
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Natamycin treatment reduces the quality changes of postharvest mulberry fruit during storage
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Alkaline extractive crude polysaccharide from Russula senecis possesses antioxidant potential and stimulates innate immunity response
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Triterpenoids and Polysaccharide Fractions ofGanoderma tsugaeExert Different Effects on Antiallergic Activities
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Modification of Soluble Dietary Fiber from Millet by Selenylation and Its Immune-Enhancing Activity
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Herbal melanin inhibits colorectal cancer cell proliferation by altering redox balance, inducing apoptosis, and modulating MAPK signaling
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Sirtuin 1 inhibits lipopolysaccharide-induced inflammation in chronic myelogenous leukemia k562 cells through interacting with the Toll-like receptor 4-nuclear factor κ B-reactive oxygen species signaling axis
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Diverse roles of SARS-CoV-2 Spike and Nucleocapsid proteins in EndMT stimulation through the TGF-β-MRTF axis inhibited by aspirin
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Emerging Roles of Ganoderma Lucidum in Anti-Aging
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New Perspective in Dietary Supplementation: Bovine Colostrum and Noni Juice Synergic Protective Effects on Intestinal Epithelium and Microbiota
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TLR2 Activation as a Marker of Severe COVID-19 and a Potential Therapeutic Target
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Sulfated Cyclocarya paliurus polysaccharides exert immunomodulatory potential on macrophages via Toll-like receptor 4 mediated MAPK/NF-κB signaling pathways
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Lanostane triterpenoids and nor-abietane aromatic diterpenoid from Ganoderma applanatum and their neuroprotective activity
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The influence of chemically modified Gellan Gum on macrophage polarization, fibroblast differentiation, and collagen orientation
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Dictyophora indusiata polysaccharide mediates priming of the NLRP3 inflammasome activation via TLR4/ NF-κB signaling pathway to exert immunostimulatory effects
inferred← citeshttps://doi.org/10.3389/fimmu.2023.1147641openalex-snapshot
Immunomodulatory function and anti-tumor mechanism of natural polysaccharides: A review
inferred← citeshttps://doi.org/10.3389/fimmu.2023.1361355openalex-snapshot
Corrigendum: Immunomodulatory function and anti-tumor mechanism of natural polysaccharides: a review
inferred← citeshttps://doi.org/10.3389/fphar.2018.00475openalex-snapshot
Arctigenin Induces an Activation Response in Porcine Alveolar Macrophage Through TLR6-NOX2-MAPKs Signaling Pathway
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Ganoderma: A Cancer Immunotherapy Review
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A Poly-D-Mannose Synthesized by a One-Pot Method Exhibits Anti-Biofilm, Antioxidant, and Anti-Inflammatory Properties In Vitro
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Ziziphus jujuba “Huizao” Polysaccharides Exert Immunomodulatory Activity In Vitro and In Vivo by Modulating the TLR4/MAPK/NF-κB Signalling Pathway
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Roles of PRR-Mediated Signaling Pathways in the Regulation of Oxidative Stress and Inflammatory Diseases
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Novel Pectic Polysaccharides Isolated from Immature Honey Pomelo Fruit with High Immunomodulatory Activity
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A New Galactoglucomannan from the Mycelium of the Medicinal Parasitic Fungus Cordyceps cicadae and Its Immunomodulatory Activity In Vitro and In Vivo
inferred← citeshttps://doi.org/10.3390/molecules29061370openalex-snapshot
Structural Characterization and Immunoenhancing Properties of Polysaccharide CPTM-P1 from Taxus media
inferred← citeshttps://doi.org/10.3892/etm.2018.6073openalex-snapshot
Immunomodulatory effect of Schisandra polysaccharides in cyclophosphamide‑induced immunocompromised mice
inferred← citeshttps://doi.org/10.3892/etm.2022.11316openalex-snapshot
Immunostimulatory activity of soybean hull polysaccharide on macrophages
inferred← citeshttps://doi.org/10.5943/mycosphere/8/10/5openalex-snapshot
Mycosphere Essays 20: Therapeutic potential of Ganoderma species: Insights into its use as traditional medicine
inferred← citeshttps://doi.org/10.6084/m9.figshare.25918917openalex-snapshot
Additional file 1 of Diverse roles of SARS-CoV-2 Spike and Nucleocapsid proteins in EndMT stimulation through the TGF-β-MRTF axis inhibited by aspirin
inferred← citeshttps://doi.org/10.62382/jcbt.v2i1.28openalex-snapshot
Enhancing Gastrointеstinal (GI) Cancer Therapies with Ganoderma Lucidum: A Review of Mechanisms and Efficacy
inferred← citeshttps://doi.org/10.71336/jabs.1585openalex-snapshot
Effects of Аstragalus dasyanthus Extracts on the level of DNA damages in human lymphocytes
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