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A Phase I/II Trial of Intensity Modulated Radiation (IMRT) Dose Escalation With Concurrent Fixed-dose Rate Gemcitabine (FDR-G) in Patients With Unresectable Pancreatic Cancer
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Outgoing claims: the papers this work cites, builds on, or argues with.
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External beam versus intraoperative and external beam irradiation for locally advanced pancreatic cancer
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Feasibility and efficacy of high dose conformal radiotherapy for patients with locally advanced pancreatic carcinoma
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Radiosensitization of pancreatic cancer cells by 2′,2′-difluoro-2′-deoxycytidine
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Adjuvant therapy in pancreatic cancer: Phase I trial of radiation dose escalation with concurrent full-dose gemcitabine
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Full-Dose Gemcitabine and Concurrent Radiotherapy for Unresectable Pancreatic Cancer
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Intraoperative Radiotherapy for Resected Pancreatic Cancer: A Multi-Institutional Retrospective Analysis of 210 Patients
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Intraoperative Radiotherapy for Unresectable Pancreatic Cancer: A Multi-Institutional Retrospective Analysis of 144 Patients
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Phase III trial comparing intensive induction chemoradiotherapy (60 Gy, infusional 5-FU and intermittent cisplatin) followed by maintenance gemcitabine with gemcitabine alone for locally advanced unresectable pancreatic cancer. Definitive results of the 2000–01 FFCD/SFRO study
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Sequential Designs for Phase I Clinical Trials with Late‐Onset Toxicities
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Potential for dose‐escalation and reduction of risk in pancreatic cancer using IMRT optimization with lexicographic ordering and gEUD‐based cost functions
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A phase I clinical, plasma, and cellular pharmacology study of gemcitabine.
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Phase I Trial of Twice-Weekly Gemcitabine and Concurrent Radiation in Patients With Advanced Pancreatic Cancer
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Phase I Trial of Radiation Dose Escalation With Concurrent Weekly Full-Dose Gemcitabine in Patients With Advanced Pancreatic Cancer
inferredcites →https://doi.org/10.1200/jco.2003.09.140openalex-snapshot
Randomized Phase II Comparison of Dose-Intense Gemcitabine: Thirty-Minute Infusion and Fixed Dose Rate Infusion in Patients With Pancreatic Adenocarcinoma
inferredcites →https://doi.org/10.1200/jco.2004.03.129openalex-snapshot
Phase I Trial Using a Time-to-Event Continual Reassessment Strategy for Dose Escalation of Cisplatin Combined With Gemcitabine and Radiation Therapy in Pancreatic Cancer
inferredcites →https://doi.org/10.1200/jco.2007.13.9014openalex-snapshot
Full-Dose Gemcitabine With Concurrent Radiation Therapy in Patients With Nonmetastatic Pancreatic Cancer: A Multicenter Phase II Trial
inferredcites →https://doi.org/10.1200/jco.2008.17.7188openalex-snapshot
DPC4 Gene Status of the Primary Carcinoma Correlates With Patterns of Failure in Patients With Pancreatic Cancer
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A randomized phase III study of gemcitabine in combination with radiation therapy versus gemcitabine alone in patients with localized, unresectable pancreatic cancer: E4201
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Phase II Study of Bevacizumab With Concurrent Capecitabine and Radiation Followed by Maintenance Gemcitabine and Bevacizumab for Locally Advanced Pancreatic Cancer: Radiation Therapy Oncology Group RTOG 0411
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Radiosensitization By Gemcitabine Fixed-Dose-Rate Infusion Versus Bolus Injection in a Pancreatic Cancer Model
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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inferred← citeshttps://doi.org/10.1158/1078-0432.ccr-12-3748openalex-snapshot
Sensitization of Pancreatic Cancer to Chemoradiation by the Chk1 Inhibitor MK8776
inferred← citeshttps://doi.org/10.1158/1078-0432.ccr-13-0788openalex-snapshot
Inhibition of Protein Phosphatase 2A Radiosensitizes Pancreatic Cancers by Modulating CDC25C/CDK1 and Homologous Recombination Repair
inferred← citeshttps://doi.org/10.1158/1078-0432.ccr-14-1038openalex-snapshot
Combined Inhibition of Wee1 and PARP1/2 for Radiosensitization in Pancreatic Cancer
inferred← citeshttps://doi.org/10.1177/1533033818783879openalex-snapshot
Effectiveness and Safety of Simultaneous Integrated Boost-Proton Beam Therapy for Localized Pancreatic Cancer
inferred← citeshttps://doi.org/10.1177/1533034616650778openalex-snapshot
Can Stereotactic Body Radiation Therapy Be a Viable and Efficient Therapeutic Option for Unresectable Locally Advanced Pancreatic Adenocarcinoma? Results of a Phase 2 Study
inferred← citeshttps://doi.org/10.1177/17562848261465516openalex-snapshot
Survival benefit of particle chemoradiotherapy in locally advanced unresectable pancreatic cancer: a systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1186/1748-717x-7-156openalex-snapshot
Radiation dose ≥54 Gy and CA 19–9 response are associated with improved survival for unresectable, non-metastatic pancreatic cancer treated with chemoradiation
inferred← citeshttps://doi.org/10.1186/1748-717x-9-11openalex-snapshot
Adequacy of inhale/exhale breathhold CT based ITV margins and image-guided registration for free-breathing pancreas and liver SBRT
inferred← citeshttps://doi.org/10.1186/1748-717x-9-146openalex-snapshot
Challenges in using 18 F-fluorodeoxyglucose-PET-CT to define a biological radiotherapy boost volume in locally advanced pancreatic cancer
inferred← citeshttps://doi.org/10.1186/s12874-020-01012-zopenalex-snapshot
Practicalities in running early-phase trials using the time-to-event continual reassessment method (TiTE-CRM) for interventions with long toxicity periods using two radiotherapy oncology trials as examples
inferred← citeshttps://doi.org/10.1186/s12885-019-5307-zopenalex-snapshot
Study protocol: a multi-centre randomised study of induction chemotherapy followed by capecitabine ± nelfinavir with high- or standard-dose radiotherapy for locally advanced pancreatic cancer (SCALOP-2)
inferred← citeshttps://doi.org/10.1186/s12885-021-08440-0openalex-snapshot
Is more better? An analysis of toxicity and response outcomes from dose-finding clinical trials in cancer
inferred← citeshttps://doi.org/10.1186/s13014-018-1063-5openalex-snapshot
Clinical evaluation of intensity-modulated radiotherapy for locally advanced pancreatic cancer
inferred← citeshttps://doi.org/10.1186/s13014-018-1138-3openalex-snapshot
Stereotactic ablative radiotherapy (SABR) as primary, adjuvant, consolidation and re-treatment option in pancreatic cancer: scope for dose escalation and lessons for toxicity
inferred← citeshttps://doi.org/10.1186/s13014-018-1158-zopenalex-snapshot
Dose escalation of radiation therapy with or without induction chemotherapy for unresectable locally advanced pancreatic cancer
inferred← citeshttps://doi.org/10.1186/s13014-018-1165-0openalex-snapshot
Comparison of different treatment planning approaches for intensity-modulated proton therapy with simultaneous integrated boost for pancreatic cancer
inferred← citeshttps://doi.org/10.1186/s13014-019-1275-3openalex-snapshot
Online adaptive magnetic resonance guided radiotherapy for pancreatic cancer: state of the art, pearls and pitfalls
inferred← citeshttps://doi.org/10.1186/s13014-019-1308-yopenalex-snapshot
MR-guidance in clinical reality: current treatment challenges and future perspectives
inferred← citeshttps://doi.org/10.1186/s13014-020-01592-6openalex-snapshot
Radiobiological model-based approach to determine the potential of dose-escalated robust intensity-modulated proton radiotherapy in reducing gastrointestinal toxicity in the treatment of locally advanced unresectable pancreatic cancer of the head
inferred← citeshttps://doi.org/10.1200/jco.19.00730openalex-snapshot
Dose Escalation Trial of the Wee1 Inhibitor Adavosertib (AZD1775) in Combination With Gemcitabine and Radiation for Patients With Locally Advanced Pancreatic Cancer
inferred← citeshttps://doi.org/10.1200/jco.2013.54.6051openalex-snapshot
Adaptive Dose-Finding Studies: A Review of Model-Guided Phase I Clinical Trials
inferred← citeshttps://doi.org/10.1200/jco.2014.55.2281openalex-snapshot
Milestones in the Use of Combined-Modality Radiation Therapy and Chemotherapy
inferred← citeshttps://doi.org/10.1200/po.19.00057openalex-snapshot
Early-Phase Platform Trials: A New Paradigm for Dose Finding and Treatment Screening in the Era of Precision Oncology
inferred← citeshttps://doi.org/10.1200/po.22.00133openalex-snapshot
Implementation of the Time-to-Event Continuous Reassessment Method Design in a Phase I Platform Trial Testing Novel Radiotherapy-Drug Combinations—CONCORDE
inferred← citeshttps://doi.org/10.1245/s10434-013-3344-4openalex-snapshot
The Promise of Modern Radiotherapy in Resected Pancreatic Adenocarcinoma: A Response to Bekaii-Saab et al.
inferred← citeshttps://doi.org/10.1259/bjr.20210044openalex-snapshot
The role of radiotherapy in locally advanced pancreatic cancer
inferred← citeshttps://doi.org/10.1371/journal.pone.0166606openalex-snapshot
Neoadjuvant Gemcitabine Chemotherapy followed by Concurrent IMRT Simultaneous Boost Achieves High R0 Resection in Borderline Resectable Pancreatic Cancer Patients
inferred← citeshttps://doi.org/10.1371/journal.pone.0186341openalex-snapshot
Dose-escalated radiotherapy for unresectable or locally recurrent pancreatic cancer: Dose volume analysis, toxicity and outcome of 28 consecutive patients
inferred← citeshttps://doi.org/10.1371/journal.pone.0210758openalex-snapshot
Computed tomography based radiomic signature as predictive of survival and local control after stereotactic body radiation therapy in pancreatic carcinoma
inferred← citeshttps://doi.org/10.14694/edbook_am.2014.34.e157openalex-snapshot
Current Controversies in the Stage-Specific Multidisciplinary Management of Pancreatic Cancer
inferred← citeshttps://doi.org/10.1586/14737140.2014.952286openalex-snapshot
Stereotactic body radiation therapy in pancreatic cancer: the new frontier
inferred← citeshttps://doi.org/10.1593/tlo.13724openalex-snapshot
Phase II Trial of Cetuximab and Conformal Radiotherapy Only in Locally Advanced Pancreatic Cancer with Concurrent Tissue Sampling Feasibility Study
inferred← citeshttps://doi.org/10.21037/apm-23-560openalex-snapshot
Palliative radiotherapy for pancreatic cancer
inferred← citeshttps://doi.org/10.21037/jgo-22-961openalex-snapshot
MR-linac based radiation therapy in gastrointestinal cancers: a narrative review
inferred← citeshttps://doi.org/10.21037/jgo.2017.03.04openalex-snapshot
Proton beam reirradiation for locally recurrent pancreatic adenocarcinoma
inferred← citeshttps://doi.org/10.21037/jgo.2018.03.07openalex-snapshot
Review and current state of radiation therapy for locally advanced pancreatic adenocarcinoma
inferred← citeshttps://doi.org/10.21037/jgo.2018.03.14openalex-snapshot
Pencil beam scanning versus passively scattered proton therapy for unresectable pancreatic cancer
inferred← citeshttps://doi.org/10.21037/jgo.2019.03.02openalex-snapshot
Proton beam radiotherapy for pancreas cancer
inferred← citeshttps://doi.org/10.21037/jgo.2019.03.14openalex-snapshot
Heavy charged particles for gastrointestinal cancers
inferred← citeshttps://doi.org/10.2147/ott.s311567openalex-snapshot
Carbon-Ion Beam Irradiation and the miR-200c Mimic Effectively Eradicate Pancreatic Cancer Stem Cells Under in vitro and in vivo Conditions
inferred← citeshttps://doi.org/10.2196/84607openalex-snapshot
Stereotactic Adaptive Radiation Therapy for Borderline Resectable or Locally Advanced Pancreatic Cancer to Minimize Gastrointestinal Toxicity (ARTIA-Pancreas): Protocol for a Single-Arm Prospective Trial
inferred← citeshttps://doi.org/10.23889/suthesis.64844openalex-snapshot
Monte Carlo Modelling for Photon and Proton Therapy in Heterogenous Tissue and Prosthesis Material
inferred← citeshttps://doi.org/10.3109/0284186x.2012.762997openalex-snapshot
Proton therapy with concomitant capecitabine for pancreatic and ampullary cancers is associated with a low incidence of gastrointestinal toxicity
inferred← citeshttps://doi.org/10.3109/0284186x.2013.813072openalex-snapshot
Comparing dose-volume histogram and radiobiological endpoints for ranking intensity-modulated arc therapy and 3D-radiotherapy treatment plans for locally-advanced pancreatic cancer
inferred← citeshttps://doi.org/10.3322/caac.21190openalex-snapshot
Recent progress in pancreatic cancer
inferred← citeshttps://doi.org/10.3389/fonc.2020.517061openalex-snapshot
Dose–Volume and Radiobiological Model-Based Comparative Evaluation of the Gastrointestinal Toxicity Risk of Photon and Proton Irradiation Plans in Localized Pancreatic Cancer Without Distant Metastasis
inferred← citeshttps://doi.org/10.3390/cancers12010163openalex-snapshot
Clinical Limitations of Photon, Proton and Carbon Ion Therapy for Pancreatic Cancer
inferred← citeshttps://doi.org/10.3390/cancers17061036openalex-snapshot
Temporal Validation of an FDG-PET-Radiomic Model for Distant-Relapse-Free-Survival After Radio-Chemotherapy for Pancreatic Adenocarcinoma
inferred← citeshttps://doi.org/10.3390/cancers17182959openalex-snapshot
Radiotherapy for Locally Advanced Pancreatic Cancer in the Modern Era: A Systematic Review and Meta-Analysis
inferred← citeshttps://doi.org/10.3390/ijms22136825openalex-snapshot
Gemcitabine-Based Chemoradiotherapy Enhanced by a PARP Inhibitor in Pancreatic Cancer Cell Lines
inferred← citeshttps://doi.org/10.3410/f.725291201.793554052openalex-snapshot
Faculty Opinions recommendation of Phase 2 multi-institutional trial evaluating gemcitabine and stereotactic body radiotherapy for patients with locally advanced unresectable pancreatic adenocarcinoma.
inferred← citeshttps://doi.org/10.3748/wjg.v21.i31.9420openalex-snapshot
Robotic radiosurgery in pancreatic cancer: A systematic review
inferred← citeshttps://doi.org/10.3857/roj.2018.00073openalex-snapshot
Effectiveness and feasibility of concurrent chemoradiotherapy using simultaneous integrated boost-intensity modulated radiotherapy with and without induction chemotherapy for locally advanced pancreatic cancer
inferred← citeshttps://doi.org/10.3978/j.issn.1000-9604.2015.04.12openalex-snapshot
Advances of stereotactic body radiotherapy in pancreatic cancer.
inferred← citeshttps://doi.org/10.3978/j.issn.2078-6891.2015.014openalex-snapshot
Adjuvant radiation therapy for pancreatic cancer: a review of the old and the new.
inferred← citeshttps://doi.org/10.4161/cc.10.24.18661openalex-snapshot
Selective radiosensitization of p53 mutant pancreatic cancer cells by combined inhibition of Chk1 and PARP1
inferred← citeshttps://doi.org/10.4172/2157-2518.1000147openalex-snapshot
Glycogen Synthase Kinase 3β in Pancreatic Cancer and its Implications in Chemotherapy and Radiation Therapy
inferred← citeshttps://doi.org/10.4251/wjgo.v7.i10.241openalex-snapshot
Management of borderline resectable pancreatic cancer
inferred← citeshttps://doi.org/10.5009/gnl16014openalex-snapshot
Is the Use of Intensity-Modulated Radiotherapy Beneficial for Pancreatic Cancer Patients?
inferred← citeshttps://doi.org/10.5402/2012/572342openalex-snapshot
Dose-Painted Intensity Modulated Radiation Therapy Improves Local Control for Locally Advanced Pancreas Cancer
inferred← citeshttps://doi.org/10.5603/rpor.a2022.0045openalex-snapshot
Recurrence patterns of pancreatic cancer treated with adjuvant intensity modulated radiotherapy
inferred← citeshttps://doi.org/10.6004/jnccn.2025.7013openalex-snapshot
Lessons Learned About Acute and Late Toxicity After Two Decades of Experience With Pancreatic SBRT
inferred← citeshttps://doi.org/10.6084/m9.figshare.12544574openalex-snapshot
Additional file 6 of Radiobiological model-based approach to determine the potential of dose-escalated robust intensity-modulated proton radiotherapy in reducing gastrointestinal toxicity in the treatment of locally advanced unresectable pancreatic cancer of the head
inferred← citeshttps://doi.org/10.6084/m9.figshare.12545087openalex-snapshot
Additional file 1 of Practicalities in running early-phase trials using the time-to-event continual reassessment method (TiTE-CRM) for interventions with long toxicity periods using two radiotherapy oncology trials as examples
inferred← citeshttps://doi.org/10.6084/m9.figshare.14913431openalex-snapshot
Additional file 1 of Is more better? An analysis of toxicity and response outcomes from dose-finding clinical trials in cancer
inferred← citeshttps://doi.org/10.70675/a02380f0zd300z4502z9095zbb8f3c3c76d3openalex-snapshot
Optimisation de la chimio-radiothérapie à base de gemcitabine par un inhibiteur de poly-ADP ribose polymérase dans les cancers du pancréas
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