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Granzyme B and Perforin Are Important for Regulatory T Cell-Mediated Suppression of Tumor Clearance
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/stem.5530070204openalex-snapshot
Removal of peripheral blood monocytes by phenylalanine methyl ester has no effect on the colony growth of hematopoietic progenitor cells
inferredcites →https://doi.org/10.1007/s00262-006-0264-1openalex-snapshot
NK cells rapidly remove B16F10 tumor cells in a perforin and interferon-gamma independent manner in vivo
inferredcites →https://doi.org/10.1016/0008-8749(90)90051-ropenalex-snapshot
Depletion of macrophages expressing I-J antigen results in efficient generation of alloreactive cytotoxic T lymphocytes
inferredcites →https://doi.org/10.1016/0092-8674(94)90376-xopenalex-snapshot
Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells
inferredcites →https://doi.org/10.1016/j.ccr.2005.10.012openalex-snapshot
TGF-β directly targets cytotoxic T cell functions during tumor evasion of immune surveillance
inferredcites →https://doi.org/10.1016/j.immuni.2004.07.017openalex-snapshot
The Immunobiology of Cancer Immunosurveillance and Immunoediting
inferredcites →https://doi.org/10.1016/j.immuni.2004.09.002openalex-snapshot
Human T Regulatory Cells Can Use the Perforin Pathway to Cause Autologous Target Cell Death
inferredcites →https://doi.org/10.1016/j.immuni.2005.08.001openalex-snapshot
Perforin Triggers a Plasma Membrane-Repair Response that Facilitates CTL Induction of Apoptosis
inferredcites →https://doi.org/10.1016/j.immuni.2007.04.010openalex-snapshot
Acquisition of Murine NK Cell Cytotoxicity Requires the Translation of a Pre-existing Pool of Granzyme B and Perforin mRNAs
inferredcites →https://doi.org/10.1016/j.semcancer.2005.11.005openalex-snapshot
Regulatory T cells in immune surveillance and treatment of cancer
inferredcites →https://doi.org/10.1016/s1074-7613(03)00032-3openalex-snapshot
Granzyme B-Induced Apoptosis Requires Both Direct Caspase Activation and Relief of Caspase Inhibition
inferredcites →https://doi.org/10.1016/s1074-7613(03)00050-5openalex-snapshot
Caspase Activation by Granzyme B Is Indirect, and Caspase Autoprocessing Requires the Release of Proapoptotic Mitochondrial Factors
inferredcites →https://doi.org/10.1038/319675a0openalex-snapshot
Selective rejection of H–2-deficient lymphoma variants suggests alternative immune defence strategy
inferredcites →https://doi.org/10.1038/ni.1840openalex-snapshot
Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells
inferredcites →https://doi.org/10.1038/ni1180openalex-snapshot
Mechanisms of suppression by suppressor T cells
inferredcites →https://doi.org/10.1038/ni904openalex-snapshot
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
inferredcites →https://doi.org/10.1038/ni909openalex-snapshot
An essential role for Scurfin in CD4+CD25+ T regulatory cells
inferredcites →https://doi.org/10.1038/nm1001-1118openalex-snapshot
Immune-mediated eradication of tumors through the blockade of transforming growth factor-β signaling in T cells
inferredcites →https://doi.org/10.1038/nmeth779openalex-snapshot
Real-time imaging of ligand-induced IKK activation in intact cells and in living mice
inferredcites →https://doi.org/10.1038/nri1083openalex-snapshot
The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal
inferredcites →https://doi.org/10.1038/nri1806openalex-snapshot
Regulatory T cells, tumour immunity and immunotherapy
inferredcites →https://doi.org/10.1073/pnas.050588297openalex-snapshot
In vivo natural killer cell activities revealed by natural killer cell-deficient mice
inferredcites →https://doi.org/10.1073/pnas.0509249103openalex-snapshot
Suppression of natural killer cell-mediated bone marrow cell rejection by CD4 + CD25 + regulatory T cells
inferredcites →https://doi.org/10.1074/jbc.272.32.20236openalex-snapshot
Residual Cytotoxicity and Granzyme K Expression in Granzyme A-deficient Cytotoxic Lymphocytes
inferredcites →https://doi.org/10.1074/jbc.274.7.3953openalex-snapshot
BCL-2 Blocks Perforin-induced Nuclear Translocation of Granzymes Concomitant with Protection against the Nuclear Events of Apoptosis
inferredcites →https://doi.org/10.1084/jem.185.5.855openalex-snapshot
Granzyme B (GraB) Autonomously Crosses the Cell Membrane and Perforin Initiates Apoptosis and GraB Nuclear Localization
inferredcites →https://doi.org/10.1084/jem.191.4.661openalex-snapshot
Differential Tumor Surveillance by Natural Killer (Nk) and Nkt Cells
inferredcites →https://doi.org/10.1084/jem.192.5.755openalex-snapshot
Perforin-Mediated Cytotoxicity Is Critical for Surveillance of Spontaneous Lymphoma
inferredcites →https://doi.org/10.1084/jem.20041130openalex-snapshot
Concomitant Tumor Immunity to a Poorly Immunogenic Melanoma Is Prevented by Regulatory T Cells
inferredcites →https://doi.org/10.1084/jem.20051511openalex-snapshot
CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor–β–dependent manner
inferredcites →https://doi.org/10.1093/intimm/13.4.459openalex-snapshot
NK cells and NKT cells collaborate in host protection from methylcholanthrene-induced fibrosarcoma
inferredcites →https://doi.org/10.1093/intimm/dxn028openalex-snapshot
NK cells and NKT cells collaborate in host protection from methylcholanthrene-induced fibrosarcoma
inferredcites →https://doi.org/10.1126/science.1079490openalex-snapshot
Control of Regulatory T Cell Development by the Transcription Factor Foxp3
inferredcites →https://doi.org/10.1146/annurev.immunol.20.100201.131730openalex-snapshot
Lymphocyte-Mediated Cytotoxicity
inferredcites →https://doi.org/10.1146/annurev.immunol.21.120601.141122openalex-snapshot
N aturally A rising CD4+R egulatory T C ells for I mmunologic S elf -T olerance and N egative C ontrol of I mmune R esponses
inferredcites →https://doi.org/10.1146/annurev.immunol.21.120601.141135openalex-snapshot
Does the Immune System See Tumors as Foreign or Self?
inferredcites →https://doi.org/10.1146/annurev.immunol.22.012703.104803openalex-snapshot
The Three Es of Cancer Immunoediting
inferredcites →https://doi.org/10.1182/blood-2004-03-0859openalex-snapshot
Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells
inferredcites →https://doi.org/10.1182/blood-2005-02-0734openalex-snapshot
c-Myc rapidly induces acute myeloid leukemia in mice without evidence of lymphoma-associated antiapoptotic mutations
inferredcites →https://doi.org/10.1182/blood-2005-11-4502openalex-snapshot
Activated CD4+CD25+ T cells selectively kill B lymphocytes
inferredcites →https://doi.org/10.4049/jimmunol.155.3.1151openalex-snapshot
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
inferredcites →https://doi.org/10.4049/jimmunol.159.11.5516openalex-snapshot
TCR vaccines for active immunotherapy of T cell malignancies
inferredcites →https://doi.org/10.4049/jimmunol.164.6.3229openalex-snapshot
Tumor Immunity in Perforin-Deficient Mice: A Role for CD95 (Fas/APO-1)
inferredcites →https://doi.org/10.4049/jimmunol.167.4.2068openalex-snapshot
A Central Role for Death Receptor-Mediated Apoptosis in the Rejection of Tumors by NK Cells
inferredcites →https://doi.org/10.4049/jimmunol.174.4.1783openalex-snapshot
Cutting Edge: Contact-Mediated Suppression by CD4+CD25+ Regulatory Cells Involves a Granzyme B-Dependent, Perforin-Independent Mechanism
inferredcites →https://doi.org/10.4049/jimmunol.174.4.2124openalex-snapshot
Granzyme B and the Downstream Granzymes C and/or F Are Important for Cytotoxic Lymphocyte Functions
inferredcites →https://doi.org/10.4049/jimmunol.174.5.2591openalex-snapshot
CD8+ T Cell Immunity Against a Tumor/Self-Antigen Is Augmented by CD4+ T Helper Cells and Hindered by Naturally Occurring T Regulatory Cells
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Human FOXP 3+ T regulatory cell heterogeneity
inferred← citeshttps://doi.org/10.1002/eji.200738114openalex-snapshot
How many mechanisms do regulatory T cells need?
inferred← citeshttps://doi.org/10.1002/eji.200939688openalex-snapshot
Dynamics of peripheral tolerance and immune regulation mediated by Treg
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Killing of myeloid APCs via HLA class I, CD2 and CD226 defines a novel mechanism of suppression by human Tr1 cells
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Lack of IL‐2 in PPAR‐α‐deficient mice triggers allergic contact dermatitis by affecting regulatory T cells
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Human tumor‐induced and naturally occurring Treg cells differentially affect NK cells activated by either IL‐2 or target cells
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Eomesodermin controls a unique differentiation program in human IL‐10 and IFN‐γ coproducing regulatory T cells
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Eomesodermin‐expressing type 1 regulatory (EOMES + Tr1)‐like T cells: Basic biology and role in immune‐mediated diseases
inferred← citeshttps://doi.org/10.1002/eji.202170126openalex-snapshot
Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)
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Regulatory T‐cell‐derived interleukin‐15 shapes cytotoxic T cell memory
inferred← citeshttps://doi.org/10.1002/ibd.21107openalex-snapshot
Perforin deficiency attenuates inflammation and tumor growth in colitis-associated cancer
inferred← citeshttps://doi.org/10.1002/ijc.25429openalex-snapshot
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Local targets for immune therapy to cancer: Tumor draining lymph nodes and tumor microenvironment
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Targeting type I collagen for cancer treatment
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IL-10 producing CD8+ CD122+ PD-1+ regulatory T cells are expanded by dendritic cells silenced for Allograft Inflammatory Factor-1
inferred← citeshttps://doi.org/10.1002/jlb.5ru0222-082ropenalex-snapshot
Direct and indirect regulation of the tumor immune microenvironment by VEGF
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The role of regulatory T cells in nervous system pathologies
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Supramolecular Coassembled Peptide Hydrogels for Efficient Anticancer Therapy by RNS‐Based PDT and Immune Microenvironment Regulation
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Different subpopulations of regulatory T cells in human autoimmune disease, transplantation, and tumor immunity
inferred← citeshttps://doi.org/10.1002/mco2.390openalex-snapshot
The role of CD4+ T cells in tumor and chronic viral immune responses
inferred← citeshttps://doi.org/10.1002/mco2.669openalex-snapshot
Posttransplant complications: molecular mechanisms and therapeutic interventions
inferred← citeshttps://doi.org/10.1002/mco2.71044openalex-snapshot
Liver Metastases from Colorectal Cancer: From Pathogenesis to Current Treatment
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Loss of BAP1 expression is associated with an immunosuppressive microenvironment in uveal melanoma, with implications for immunotherapy development
inferred← citeshttps://doi.org/10.1002/smsc.202500481openalex-snapshot
Regulatory T Cells and Nanomaterials: Dual Perspectives in Therapeutics and Immunomodulation
inferred← citeshttps://doi.org/10.1002/stem.3051openalex-snapshot
Metabolism and Gut Microbiota in Cancer Immunoediting, CD8/Treg Ratios, Immune Cell Homeostasis, and Cancer (Immuno)Therapy: Concise Review
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The role of regulatory T cells in neurodegenerative diseases
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Immunological Landscape of Head and Neck Cancer: Mechanisms of Immune Escape and the Tumor Microenvironment
inferred← citeshttps://doi.org/10.1007/82_2010_50openalex-snapshot
Biology and Clinical Observations of Regulatory T Cells in Cancer Immunology
inferred← citeshttps://doi.org/10.1007/82_2016_500openalex-snapshot
Linked CD4 T Cell Help: Broadening Immune Attack Against Cancer by Vaccination
inferred← citeshttps://doi.org/10.1007/82_2017_64openalex-snapshot
Immune Regulation by Ubiquitin Tagging as Checkpoint Code
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Functionally Defined T Cell Subsets in Transplantation Biology and Therapy: Regulatory T Cells and Th2 Cells
inferred← citeshttps://doi.org/10.1007/978-1-0716-1162-3_14openalex-snapshot
Determination and Quantitation of Cytotoxic T Cell-Mediated Cell Death
inferred← citeshttps://doi.org/10.1007/978-1-0716-3754-8_3openalex-snapshot
T Cell Subsets and Immune Homeostasis
inferred← citeshttps://doi.org/10.1007/978-1-4419-6615-5_21openalex-snapshot
Natural Killer Cells for Adoptive Immunotherapy
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Inflammatory Mediators in Tumorigenesis and Metastasis
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Matters of Life and Death in the Immune System
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T Regulatory Cells and Cancer Immunotherapy
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Role of Myeloid-Derived Suppressor Cells and Regulatory T-Cells in the Tuberculous Granuloma
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CCL22 Signaling in the Tumor Environment
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Regulatory T Cells in the Tumor Microenvironment
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Targeting Inhibitory Cells Such as Tregs and MDSCs in the Tuberculous Granuloma
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Inflammation in Pulmonary Arterial Hypertension
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Vascular Modulation of Antitumor Immunity: A Crosstalk Between Immune Cells and the Tumor Vasculature
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Cellular Immune Responses in Tumor Microenvironment
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Vascular Modulation of Antitumor Immunity: A Crosstalk Between Immune Cells and the Tumor Vasculature
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T-reg Homeostasis and Functions in Ageing
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Microbiome and Gut Immunity: T Cells
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T-reg Homeostasis and Functions in Aging
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Interactions Between NK Cells and Regulatory T Cells
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Therapeutic Targeting Regulatory T Cells in Tumor
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usEPs as a Possible Immunotherapy
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Regulatory T Cell-Mediated Tissue Repair
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Mechanisms regulating the development and function of natural regulatory T cells
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Regulatory T Cell as a Target for Cancer Therapy
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Immune system: a double-edged sword in cancer
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Bridging the divide: unveiling mutual immunological pathways of cancer and pregnancy
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The development and function of regulatory T cells
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How tumors might withstand γδ T-cell attack
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CD4 and CD8 T lymphocyte interplay in controlling tumor growth
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Regulatorische T-Zellen und NK-Zellen bei Krebspatienten
inferred← citeshttps://doi.org/10.1007/s00109-010-0602-9openalex-snapshot
Reciprocal granzyme/perforin-mediated death of human regulatory and responder T cells is regulated by interleukin-2 (IL-2)
inferred← citeshttps://doi.org/10.1007/s00210-024-03493-xopenalex-snapshot
Immune cell traits and causal relationships with cholecystitis: a mendelian randomization analysis
inferred← citeshttps://doi.org/10.1007/s00262-010-0866-5openalex-snapshot
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Tumor-specific CD4+ T cells develop cytotoxic activity and eliminate virus-induced tumor cells in the absence of regulatory T cells
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IL-10 inducible CD8+ regulatory T-cells are enriched in patients with multiple myeloma and impact the generation of antigen-specific T-cells
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Nicotine exhausts CD8+ T cells against tumor cells through increasing miR-629-5p to repress IL2RB-mediated granzyme B expression
inferred← citeshttps://doi.org/10.1007/s00262-020-02842-yopenalex-snapshot
Metabolic reprogramming of T regulatory cells in the hypoxic tumor microenvironment
inferred← citeshttps://doi.org/10.1007/s00262-021-03041-zopenalex-snapshot
Combination therapy for hepatocellular carcinoma with diacylglycerol kinase alpha inhibition and anti-programmed cell death-1 ligand blockade
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Murine myeloid derived suppressor cells possess a range of suppressive mechanisms—Granzyme B is not among them
inferred← citeshttps://doi.org/10.1007/s00262-023-03410-wopenalex-snapshot
Murine regulatory T cells utilize granzyme B to promote tumor metastasis
inferred← citeshttps://doi.org/10.1007/s00262-023-03582-5openalex-snapshot
Enhanced T cell immune activity mediated by Drp1 promotes the efficacy of PD-1 inhibitors in treating lung cancer
inferred← citeshttps://doi.org/10.1007/s00262-024-03762-xopenalex-snapshot
Spatial cell interplay networks of regulatory T cells predict recurrence in patients with operable non-small cell lung cancer
inferred← citeshttps://doi.org/10.1007/s00281-010-0200-5openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/s00281-020-00835-8openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/s00432-020-03398-1openalex-snapshot
Prognostic role of regulatory T cells in lymphoma: a systematic review and meta-analysis
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inferred← citeshttps://doi.org/10.1007/s10067-026-08069-zopenalex-snapshot
Regulatory T cells as a potential treatment for autoimmune inflammatory rheumatic and musculoskeletal diseases
inferred← citeshttps://doi.org/10.1007/s10143-024-02353-9openalex-snapshot
Revolutionizing brain interventions: the multifaceted potential of histotripsy
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Targeting regulatory T cells in gastrointestinal cancers: current status and future perspectives
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Decreased DIO3OS Expression Predicts Poor Prognosis in Hepatocellular Carcinoma and is Associated with Immune Infiltration
inferred← citeshttps://doi.org/10.1007/s10555-010-9223-6openalex-snapshot
Interactions between lymphocytes and myeloid cells regulate pro- versus anti-tumor immunity
inferred← citeshttps://doi.org/10.1007/s10787-026-02397-xopenalex-snapshot
Natural killer cells in ovarian cancer therapy: mechanisms, evasion, and therapeutic innovations
inferred← citeshttps://doi.org/10.1007/s11033-019-04767-xopenalex-snapshot
Synergistic effect of granzyme B-azurin fusion protein on breast cancer cells
inferred← citeshttps://doi.org/10.1007/s11033-026-12310-yopenalex-snapshot
Precision Immunoregulation in transplantation: The rise of engineered Treg therapies
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Targeting regulatory T cells
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Pathological Response and Tumor Immune Microenvironment Remodeling Upon Neoadjuvant ALK-TKI Treatment in ALK-Rearranged Non-Small Cell Lung Cancer
inferred← citeshttps://doi.org/10.1007/s11670-008-0105-1openalex-snapshot
Recombinant GrB and PFP co-expression in Hep-2 cells
inferred← citeshttps://doi.org/10.1007/s11684-025-1134-6openalex-snapshot
Development of therapeutic cancer vaccines based on cancer immunity cycle
inferred← citeshttps://doi.org/10.1007/s12026-009-8124-7openalex-snapshot
Regulatory T cells and immune tolerance to tumors
inferred← citeshttps://doi.org/10.1007/s12026-010-8176-8openalex-snapshot
The role of natural regulatory T cells in infection
inferred← citeshttps://doi.org/10.1007/s12026-011-8242-xopenalex-snapshot
Activation of regulatory T cells instigates functional down-regulation of cytotoxic T lymphocytes in human breast cancer
inferred← citeshttps://doi.org/10.1007/s12026-014-8512-5openalex-snapshot
Regulatory T cells and their roles in immune dysregulation and allergy
inferred← citeshttps://doi.org/10.1007/s12026-019-09090-yopenalex-snapshot
T follicular regulatory cells suppress Tfh-mediated B cell help and synergistically increase IL-10-producing B cells in breast carcinoma
inferred← citeshttps://doi.org/10.1007/s12026-024-09481-wopenalex-snapshot
SIT1 identifies circulating hypoactive T cells with elevated cytotoxic molecule secretion in systemic lupus erythematosus patients
inferred← citeshttps://doi.org/10.1007/s12032-014-0290-3openalex-snapshot
Perforin, CD28 and CD95 expression in circulating CD4 and CD8 cells as predictors of head and neck (H&N) cancer patient survival
inferred← citeshttps://doi.org/10.1007/s12032-023-02289-yopenalex-snapshot
Evaluation of regulatory T-cells in cancer immunotherapy: therapeutic relevance of immune checkpoint inhibition
inferred← citeshttps://doi.org/10.1007/s12035-024-04281-7openalex-snapshot
Role of Regulatory T Cells in Intracerebral Hemorrhage
inferred← citeshttps://doi.org/10.1007/s12038-022-00312-4openalex-snapshot
Effects of immunosuppressants on T-cell dynamics: Understanding from a generic coarse-grained immune network model
inferred← citeshttps://doi.org/10.1007/s12602-023-10087-1openalex-snapshot
Mechanistic Insights into Immune-Microbiota Interactions and Preventive Role of Probiotics Against Autoimmune Diabetes Mellitus
inferred← citeshttps://doi.org/10.1007/s12672-025-02673-2openalex-snapshot
Unraveling the immunomodulatory role of TIM-3 in head and neck squamous cell carcinoma: implications for targeted therapy
inferred← citeshttps://doi.org/10.1007/s12672-026-05195-7openalex-snapshot
Spatially resolved FoxP3 positive lymphocyte infiltration within the tumor microenvironment predicts survival in resected pancreatic ductal adenocarcinoma
inferred← citeshttps://doi.org/10.1007/s13205-026-04922-9openalex-snapshot
Acute exercise shifts inferred immune cell composition and cytotoxic gene programs in pediatric sickle cell anemia
inferred← citeshttps://doi.org/10.1007/s13577-021-00659-0openalex-snapshot
Deciphering the influence of urinary microbiota on FoxP3+ regulatory T cell infiltration and prognosis in Chinese patients with non-muscle-invasive bladder cancer
inferred← citeshttps://doi.org/10.1007/s13770-020-00258-4openalex-snapshot
In Vitro Modeling of the Tumor Microenvironment in Tumor Organoids
inferred← citeshttps://doi.org/10.1007/s40610-023-00157-2openalex-snapshot
Immune Escape Mechanism of Cancer
inferred← citeshttps://doi.org/10.1007/s40618-016-0575-9openalex-snapshot
Low regulatory T cell and high IL-17 mRNA expression in a mouse Graves’ disease model
inferred← citeshttps://doi.org/10.1007/s40778-015-0025-1openalex-snapshot
Regulatory T Cell Immunotherapy in Immune-Mediated Diseases
inferred← citeshttps://doi.org/10.1007/s43657-025-00237-6openalex-snapshot
Immunophenotyping of Mouse Colonic Unconventional T Cells by Mapping Cell Phenomics With 22-Color Flow Cytometry Assays
inferred← citeshttps://doi.org/10.1016/b978-0-12-801577-3.00009-5openalex-snapshot
Regulatory T Cells
inferred← citeshttps://doi.org/10.1016/b978-0-12-802420-1.00003-xopenalex-snapshot
The Role of Regulatory T Cells and Indoleamine-2,3-dioxygenase in Brain Tumor Immunosuppression
inferred← citeshttps://doi.org/10.1016/b978-0-12-812102-3.00005-1openalex-snapshot
Immunological Tolerance—T Cells
inferred← citeshttps://doi.org/10.1016/b978-0-12-817868-3.00006-8openalex-snapshot
Improving responses to immunotherapy in head and neck squamous cell carcinoma
inferred← citeshttps://doi.org/10.1016/b978-0-12-818731-9.00165-8openalex-snapshot
Immunological Tolerance
inferred← citeshttps://doi.org/10.1016/b978-0-12-822620-9.00011-2openalex-snapshot
Reversing the NK inhibitory tumor microenvironment by targeting suppressive immune effectors
inferred← citeshttps://doi.org/10.1016/b978-0-12-823318-4.00024-xopenalex-snapshot
T cells in kidney injury and regeneration
inferred← citeshttps://doi.org/10.1016/b978-0-12-824465-4.00201-5openalex-snapshot
Regulatory T Cells in Tumor Immunity
inferred← citeshttps://doi.org/10.1016/b978-0-323-54427-6.00009-2openalex-snapshot
10.1016/b978-0-323-54427-6.00009-2
inferred← citeshttps://doi.org/10.1016/b978-0-443-13947-5.00007-5openalex-snapshot
Regulatory T cells and autoimmunity
inferred← citeshttps://doi.org/10.1016/b978-0-443-13947-5.00009-9openalex-snapshot
Role of regulatory T cells in the pathogenesis and therapeutics of autoimmune hepatitis
inferred← citeshttps://doi.org/10.1016/b978-0-443-13947-5.00017-8openalex-snapshot
Regulatory T cells: mechanisms of action
inferred← citeshttps://doi.org/10.1016/b978-0-443-14064-8.00045-xopenalex-snapshot
B cell-mediated immune tolerance and cancer immune evasion
inferred← citeshttps://doi.org/10.1016/b978-0-443-14064-8.00048-5openalex-snapshot
Chronic inflammation induced immunosuppression
inferred← citeshttps://doi.org/10.1016/b978-0-443-18578-6.00007-6openalex-snapshot
Cytotoxic T lymphocytes in multiple sclerosis: New targets for treatment?
inferred← citeshttps://doi.org/10.1016/b978-0-443-29005-3.00019-8openalex-snapshot
Hepatitis A virus: Exploring the role of genetics and immune players
inferred← citeshttps://doi.org/10.1016/bs.ai.2016.08.002openalex-snapshot
Context- and Tissue-Specific Regulation of Immunity and Tolerance by Regulatory T Cells
inferred← citeshttps://doi.org/10.1016/bs.apcsb.2019.11.010openalex-snapshot
Targeting FOXP3 complex ensemble in drug discovery
inferred← citeshttps://doi.org/10.1016/bs.apcsb.2021.01.003openalex-snapshot
Intrinsic and extrinsic pathways of apoptosis: Role in cancer development and prognosis
inferred← citeshttps://doi.org/10.1016/bs.ircmb.2018.07.002openalex-snapshot
Transcriptional Programs Underlying Cd4 T Cell Differentiation and Functions
inferred← citeshttps://doi.org/10.1016/bs.pmbts.2015.07.012openalex-snapshot
Microenvironment Matters
inferred← citeshttps://doi.org/10.1016/bs.pmbts.2015.08.003openalex-snapshot
Mechanisms of Surveillance of Dendritic Cells by Regulatory T Lymphocytes
inferred← citeshttps://doi.org/10.1016/j.acmx.2013.01.010openalex-snapshot
Las células T reguladoras en la enfermedad pulmonar obstructiva crónica
inferred← citeshttps://doi.org/10.1016/j.addr.2021.05.001openalex-snapshot
Hot or cold: Bioengineering immune contextures into in vitro patient-derived tumor models
inferred← citeshttps://doi.org/10.1016/j.apsb.2020.08.010openalex-snapshot
Nanomedicines modulating tumor immunosuppressive cells to enhance cancer immunotherapy
inferred← citeshttps://doi.org/10.1016/j.autrev.2014.10.012openalex-snapshot
Regulatory T-cells in autoimmune diseases: Challenges, controversies and—yet—unanswered questions
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2017.08.008openalex-snapshot
The role of human phospholipid scramblases in apoptosis: An overview
inferred← citeshttps://doi.org/10.1016/j.bbcan.2025.189259openalex-snapshot
Targeting lipid metabolism in regulatory T cells for enhancing cancer immunotherapy
inferred← citeshttps://doi.org/10.1016/j.bbcan.2025.189312openalex-snapshot
Tertiary lymphoid structures achieve ‘cold’ to ‘hot’ transition by remodeling the cold tumor microenvironment
inferred← citeshttps://doi.org/10.1016/j.bbmt.2018.07.003openalex-snapshot
Host-Derived Serine Protease Inhibitor 6 Provides Granzyme B–Independent Protection of Intestinal Epithelial Cells in Murine Graft-versus-Host Disease
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2022.121723openalex-snapshot
Inhibition of SerpinB9 to enhance granzyme B-based tumor therapy by using a modified biomimetic nanoplatform with a cascade strategy
inferred← citeshttps://doi.org/10.1016/j.biopha.2024.116359openalex-snapshot
Dysfunctional regulatory T cell: May be an obstacle to immunotherapy in cardiovascular diseases
inferred← citeshttps://doi.org/10.1016/j.canlet.2019.05.003openalex-snapshot
Treg-mediated acquired resistance to immune checkpoint inhibitors
inferred← citeshttps://doi.org/10.1016/j.canlet.2020.07.022openalex-snapshot
FoxP3+ T regulatory cells in cancer: Prognostic biomarkers and therapeutic targets
inferred← citeshttps://doi.org/10.1016/j.canlet.2024.217098openalex-snapshot
Neutrophil extracellular traps promote immune escape in hepatocellular carcinoma by up-regulating CD73 through Notch2
inferred← citeshttps://doi.org/10.1016/j.canlet.2025.217662openalex-snapshot
Pancreatic cancer precursor lesions – Can immunotherapy prevent progression into pancreatic ductal adenocarcinoma?
inferred← citeshttps://doi.org/10.1016/j.ccr.2025.216709openalex-snapshot
Ratiometric MRI probes for tumor microenvironment profiling: Design principles, multimodal validation, and future perspectives in precision oncology
inferred← citeshttps://doi.org/10.1016/j.cej.2025.168488openalex-snapshot
Monocyte/macrophage-mediated transport and intratumoral bacteria-responsive ZIF nanoplatform for enhanced immunotherapy against microsatellite-stable colorectal cancer
inferred← citeshttps://doi.org/10.1016/j.cell.2010.02.021openalex-snapshot
Th17 and Regulatory T Cells in Mediating and Restraining Inflammation
inferred← citeshttps://doi.org/10.1016/j.cell.2020.06.032openalex-snapshot
Coupled scRNA-Seq and Intracellular Protein Activity Reveal an Immunosuppressive Role of TREM2 in Cancer
inferred← citeshttps://doi.org/10.1016/j.cellimm.2008.02.001openalex-snapshot
Multi-faceted control of autoaggression: Foxp3+ regulatory T cells in murine models of organ-specific autoimmune disease
inferred← citeshttps://doi.org/10.1016/j.cellimm.2008.03.001openalex-snapshot
Interleukin-10 containing normal human serum inhibits granzyme B release but not perforin release from alloreactive and EBV-specific T cell clones
inferred← citeshttps://doi.org/10.1016/j.cellimm.2010.03.019openalex-snapshot
Tumor vaccines in 2010: Need for integration
inferred← citeshttps://doi.org/10.1016/j.cellimm.2010.04.002openalex-snapshot
Autologous stromal vascular fraction cells: A tool for facilitating tolerance in rheumatic disease
inferred← citeshttps://doi.org/10.1016/j.cellimm.2012.07.001openalex-snapshot
Tumor-infiltrating regulatory T cells delineated by upregulation of PD-1 and inhibitory receptors
inferred← citeshttps://doi.org/10.1016/j.cellimm.2014.05.004openalex-snapshot
Inhibition of CDK2 promotes inducible regulatory T-cell differentiation through TGFβ-Smad3 signaling pathway
inferred← citeshttps://doi.org/10.1016/j.cellimm.2017.05.007openalex-snapshot
Direct control of B cells by Tregs: An opportunity for long-term modulation of the humoral response
inferred← citeshttps://doi.org/10.1016/j.cellimm.2018.09.008openalex-snapshot
Restoring self-tolerance in autoimmune diseases by enhancing regulatory T-cells
inferred← citeshttps://doi.org/10.1016/j.cellimm.2020.104193openalex-snapshot
Regulatory T cell therapy: Current and future design perspectives
inferred← citeshttps://doi.org/10.1016/j.celrep.2018.10.002openalex-snapshot
Differential Roles of IL-2 Signaling in Developing versus Mature Tregs
inferred← citeshttps://doi.org/10.1016/j.celrep.2022.110447openalex-snapshot
Tumor-educated Tregs drive organ-specific metastasis in breast cancer by impairing NK cells in the lymph node niche
inferred← citeshttps://doi.org/10.1016/j.celrep.2022.110773openalex-snapshot
Aryl hydrocarbon receptor signals in epithelial cells govern the recruitment and location of Helios+ Tregs in the gut
inferred← citeshttps://doi.org/10.1016/j.celrep.2023.112275openalex-snapshot
Pharmacological boosting of cGAS activation sensitizes chemotherapy by enhancing antitumor immunity
inferred← citeshttps://doi.org/10.1016/j.celrep.2023.112813openalex-snapshot
A genetic method specifically delineates Th1-type Treg cells and their roles in tumor immunity
inferred← citeshttps://doi.org/10.1016/j.celrep.2024.114907openalex-snapshot
PD-1 endocytosis unleashes the cytolytic potential of checkpoint blockade in tumor immunity
inferred← citeshttps://doi.org/10.1016/j.clim.2023.109716openalex-snapshot
Umbilical cord blood and peripheral blood-derived regulatory T cells therapy: Progress in type 1 diabetes
inferred← citeshttps://doi.org/10.1016/j.clim.2025.110533openalex-snapshot
Increased levels of Foxp3+CD4+NKT-like cells are associated with HIV disease progression
inferred← citeshttps://doi.org/10.1016/j.coi.2015.02.003openalex-snapshot
The interplay of effector and regulatory T cells in cancer
inferred← citeshttps://doi.org/10.1016/j.critrevonc.2024.104359openalex-snapshot
The new era of lung cancer therapy: Combining immunotherapy with ferroptosis
inferred← citeshttps://doi.org/10.1016/j.critrevonc.2026.105237openalex-snapshot
Regulatory T cells in ovarian cancer: Insights into cancer immunotherapy
inferred← citeshttps://doi.org/10.1016/j.cyto.2009.01.010openalex-snapshot
Peripheral tolerance in CD8+ T cells
inferred← citeshttps://doi.org/10.1016/j.cyto.2024.156834openalex-snapshot
The possible anti-tumor effects of regulatory T cells plasticity / IL-35 in the tumor microenvironment of the major three cancer types
inferred← citeshttps://doi.org/10.1016/j.cytogfr.2009.11.002openalex-snapshot
Lymphocytes in cancer development: Polarization towards pro-tumor immunity
inferred← citeshttps://doi.org/10.1016/j.drup.2025.101328openalex-snapshot
The implied dysregulated RKIP-hypoxia axis in cancer and immune evasion: Clinical implications
inferred← citeshttps://doi.org/10.1016/j.ejcb.2025.151482openalex-snapshot
The role of prostanoids in regulatory T cells and their implications in inflammatory diseases and cancers
inferred← citeshttps://doi.org/10.1016/j.ejmech.2024.116683openalex-snapshot
Design, synthesis, and evaluation of antitumor activity of 2-arylmethoxy-4-(2-fluoromethyl-biphenyl-3-ylmethoxy) benzylamine derivatives as PD-1/PD-l1 inhibitors
inferred← citeshttps://doi.org/10.1016/j.ejphar.2017.05.009openalex-snapshot
Killer cells in atherosclerosis
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