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Interleukin-17 Promotes Autoimmunity by Triggering a Positive-Feedback Loop via Interleukin-6 Induction
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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Delayed onset and reduced severity of collagen-induced arthritis in interleukin-6-deficient mice
inferredcites →https://doi.org/10.1002/1529-0131(200007)43:7<1431::aid-anr3>3.0.co;2-eopenalex-snapshot
Current evidence for the induction of autoimmune rheumatic manifestations by cytokine therapy
inferredcites →https://doi.org/10.1002/eji.1830230515openalex-snapshot
Serum soluble interleukin‐6 receptor in MRL/lpr mice is elevated with age and mediates the interleukin‐6 signal
inferredcites →https://doi.org/10.1006/cyto.1999.0502openalex-snapshot
INTERLEUKIN 6 KNOCK-OUT MICE ARE RESISTANT TO ANTIGEN-INDUCED EXPERIMENTAL ARTHRITIS
inferredcites →https://doi.org/10.1016/1074-7613(95)90070-5openalex-snapshot
Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor
inferredcites →https://doi.org/10.1016/b978-0-12-595961-2.x5000-8openalex-snapshot
The Autoimmune Diseases
inferredcites →https://doi.org/10.1016/j.cell.2006.07.035openalex-snapshot
The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells
inferredcites →https://doi.org/10.1016/j.coph.2004.03.005openalex-snapshot
Inhibition of IL-6 for the treatment of inflammatory diseases
inferredcites →https://doi.org/10.1016/j.immuni.2006.01.001openalex-snapshot
TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells
inferredcites →https://doi.org/10.1016/j.immuni.2007.03.014openalex-snapshot
T Cell-Produced Transforming Growth Factor-β1 Controls T Cell Tolerance and Regulates Th1- and Th17-Cell Differentiation
inferredcites →https://doi.org/10.1016/j.neures.2007.04.009openalex-snapshot
Expression and role of type I collagen in a rat spinal cord contusion injury model
inferredcites →https://doi.org/10.1016/j.smim.2004.08.015openalex-snapshot
Regulation of the immune system by SOCS family adaptor proteins
inferredcites →https://doi.org/10.1016/s0952-7915(99)00035-7openalex-snapshot
Cytokines that regulate autoimmune responses
inferredcites →https://doi.org/10.1016/s1074-7613(00)80162-4openalex-snapshot
Dissection of Signaling Cascades through gp130 In Vivo
inferredcites →https://doi.org/10.1016/s1074-7613(01)00127-3openalex-snapshot
Age-Dependent T Cell Tolerance and Autoimmunity to Myelin Basic Protein
inferredcites →https://doi.org/10.1016/s1074-7613(04)00111-6openalex-snapshot
Back to Central Tolerance
inferredcites →https://doi.org/10.1016/s1359-6101(02)00017-5openalex-snapshot
Cytokines in autoimmune disease and chronic inflammatory proliferative disease
inferredcites →https://doi.org/10.1016/s1359-6101(02)00018-7openalex-snapshot
Cytokines and anti-cytokine biologicals in autoimmunity: present and future
inferredcites →https://doi.org/10.1016/s1359-6101(02)00027-8openalex-snapshot
IL-6 in autoimmune disease and chronic inflammatory proliferative disease
inferredcites →https://doi.org/10.1038/41131openalex-snapshot
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
inferredcites →https://doi.org/10.1038/90609openalex-snapshot
Toll-like receptors: critical proteins linking innate and acquired immunity
inferredcites →https://doi.org/10.1038/90935openalex-snapshot
Autoimmune disease: why and where it occurs
inferredcites →https://doi.org/10.1038/nature01355openalex-snapshot
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
inferredcites →https://doi.org/10.1038/nature02119openalex-snapshot
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
inferredcites →https://doi.org/10.1038/nature02738openalex-snapshot
Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein IκBζ
inferredcites →https://doi.org/10.1038/ni0407-345openalex-snapshot
TH-17 cells in the circle of immunity and autoimmunity
inferredcites →https://doi.org/10.1038/ni0901-802openalex-snapshot
The genetics of complex autoimmune diseases: non-MHC susceptibility genes
inferredcites →https://doi.org/10.1038/ni1254openalex-snapshot
Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
inferredcites →https://doi.org/10.1038/ni1261openalex-snapshot
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
inferredcites →https://doi.org/10.1038/ni1539openalex-snapshot
TGF-β and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain TH-17 cell–mediated pathology
inferredcites →https://doi.org/10.1038/nm1590openalex-snapshot
TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity
inferredcites →https://doi.org/10.1038/nri2093openalex-snapshot
SOCS proteins, cytokine signalling and immune regulation
inferredcites →https://doi.org/10.1038/sj.cr.7310002openalex-snapshot
GATA-3 promotes Th2 responses through three different mechanisms: induction of Th2 cytokine production, selective growth of Th2 cells and inhibition of Th1 cell-specific factors
inferredcites →https://doi.org/10.1038/sj.onc.1209281openalex-snapshot
Loss of SOCS3 in the liver promotes fibrosis by enhancing STAT3-mediated TGF-β1 production
inferredcites →https://doi.org/10.1074/jbc.m210429200openalex-snapshot
Stimulation of Airway Mucin Gene Expression by Interleukin (IL)-17 through IL-6 Paracrine/Autocrine Loop
inferredcites →https://doi.org/10.1074/jbc.m308809200openalex-snapshot
Functional Cooperation between Interleukin-17 and Tumor Necrosis Factor-α Is Mediated by CCAAT/Enhancer-binding Protein Family Members
inferredcites →https://doi.org/10.1080/08916930500050269openalex-snapshot
A genetic basis for shared autoimmunity in mouse models
inferredcites →https://doi.org/10.1084/jem.20020619openalex-snapshot
A Point Mutation of Tyr-759 in Interleukin 6 Family Cytokine Receptor Subunit gp130 Causes Autoimmune Arthritis
inferredcites →https://doi.org/10.1084/jem.20052187openalex-snapshot
Autoimmune arthritis associated with mutated interleukin (IL)-6 receptor gp130 is driven by STAT3/IL-7–dependent homeostatic proliferation of CD4+ T cells
inferredcites →https://doi.org/10.1084/jem.20062259openalex-snapshot
T cell self-reactivity forms a cytokine milieu for spontaneous development of IL-17+ Th cells that cause autoimmune arthritis
inferredcites →https://doi.org/10.1089/10430349950017734openalex-snapshot
High Levels of Foreign Gene Expression in Hepatocytes after Tail Vein Injections of Naked Plasmid DNA
inferredcites →https://doi.org/10.1093/intimm/10.5.703openalex-snapshot
IL-6-deficient mice are resistant to the induction of experimental autoimmune encephalomyelitis provoked by myelin oligodendrocyte glycoprotein
inferredcites →https://doi.org/10.1093/intimm/dxh045openalex-snapshot
The point mutation of tyrosine 759 of the IL-6 family cytokine receptor gp130 synergizes with HTLV-1 pX in promoting rheumatoid arthritis-like arthritis
inferredcites →https://doi.org/10.1093/intimm/dxm045openalex-snapshot
IL-6–gp130–STAT3 in T cells directs the development of IL-17+ Th with a minimum effect on that of Treg in the steady state
inferredcites →https://doi.org/10.1101/gad.14.14.1693openalex-snapshot
Lineage commitment in the immune system: the T helper lymphocyte grows up
inferredcites →https://doi.org/10.1101/gad.1553707openalex-snapshot
Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFκB
inferredcites →https://doi.org/10.1111/j.1365-2249.2007.03356.xopenalex-snapshot
The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease
inferredcites →https://doi.org/10.1111/j.1365-2443.2005.00900.xopenalex-snapshot
Essential role of STAT3 in cytokine‐driven NF‐κB‐mediated serum amyloid A gene expression
inferredcites →https://doi.org/10.1146/annurev.immunol.19.1.163openalex-snapshot
Anti-TNFα Therapy of Rheumatoid Arthritis: What Have We Learned?
inferredcites →https://doi.org/10.1146/annurev.immunol.7.1.145openalex-snapshot
TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties
inferredcites →https://doi.org/10.1172/jci115055openalex-snapshot
Essential role for interferon-gamma and interleukin-6 in autoimmune insulin-dependent diabetes in NOD/Wehi mice.
inferredcites →https://doi.org/10.1172/jci200421795openalex-snapshot
Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell–mediated spontaneous autoimmune arthritis in mice
inferredcites →https://doi.org/10.1172/jci28508openalex-snapshot
The IL-23/IL-17 axis in inflammation
inferredcites →https://doi.org/10.2174/1566524023362456openalex-snapshot
The Role of STATs in Apoptosis
inferredcites →https://doi.org/10.3109/08830189809042997openalex-snapshot
Interleukin 6 and its Receptor: Ten Years Later
inferredcites →https://doi.org/10.4049/jimmunol.1500168openalex-snapshot
Correction: Stat3 Activation Is Responsible for IL-6–Dependent T Cell Proliferation through Preventing Apoptosis: Generation and Characterization of T Cell–Specific Stat3-Deficient Mice
inferredcites →https://doi.org/10.4049/jimmunol.161.9.4652openalex-snapshot
Stat3 Activation Is Responsible for IL-6-Dependent T Cell Proliferation Through Preventing Apoptosis: Generation and Characterization of T Cell-Specific Stat3-Deficient Mice
inferredcites →https://doi.org/10.4049/jimmunol.162.9.5337openalex-snapshot
NF-κB-Inducing Kinase Is a Common Mediator of IL-17-, TNF-α-, and IL-1β-Induced Chemokine Promoter Activation in Intestinal Epithelial Cells
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4776231openalex-extracted
De Novo Mutations Promote Inflammation in Children with Stat3 Gain-of-Functionsyndrome by Affecting Il-1β Expression
inferred← citeshttps://doi.org/10.1002/1873-3468.14201openalex-snapshot
Making sense of IL‐6 signalling cues in pathophysiology
inferred← citeshttps://doi.org/10.1002/1873-3468.14460openalex-snapshot
Umbilical cord mesenchymal stem cell‐derived exosomes alleviate collagen‐induced arthritis by balancing the population of Th17 and regulatory T cells
inferred← citeshttps://doi.org/10.1002/2211-5463.12430openalex-snapshot
Intermittent hypoxia‐induced epiregulin expression by IL ‐6 production in human coronary artery smooth muscle cells
inferred← citeshttps://doi.org/10.1002/art.24999openalex-snapshot
A critical role of Cyr61 in interleukin‐17–dependent proliferation of fibroblast‐like synoviocytes in rheumatoid arthritis
inferred← citeshttps://doi.org/10.1002/art.30093openalex-snapshot
Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin‐17A production
inferred← citeshttps://doi.org/10.1002/art.30336openalex-snapshot
Critical proinflammatory role of thymic stromal lymphopoietin and its receptor in experimental autoimmune arthritis
inferred← citeshttps://doi.org/10.1002/art.38901openalex-snapshot
Amelioration of Tissue Fibrosis by Toll‐like Receptor 4 Knockout in Murine Models of Systemic Sclerosis
inferred← citeshttps://doi.org/10.1002/art.39086openalex-snapshot
Semaphorin 4D Contributes to Rheumatoid Arthritis by Inducing Inflammatory Cytokine Production: Pathogenic and Therapeutic Implications
inferred← citeshttps://doi.org/10.1002/art.41182openalex-snapshot
Role of Chondrocytes in the Development of Rheumatoid Arthritis Via Transmembrane Protein 147–Mediated NF ‐κB Activation
inferred← citeshttps://doi.org/10.1002/der2.113openalex-snapshot
The pathogenesis of hidradenitis suppurativa: Evolving paradigms in a complex disease
inferred← citeshttps://doi.org/10.1002/eji.200839066openalex-snapshot
Cytokine mediators of Th17 function
inferred← citeshttps://doi.org/10.1002/eji.200939333openalex-snapshot
C5a receptor‐deficient dendritic cells promote induction of Treg and Th17 cells
inferred← citeshttps://doi.org/10.1002/eji.200939566openalex-snapshot
Treatment of collagen‐induced arthritis by Natura‐α via regulation of Th‐1/Th‐17 responses
inferred← citeshttps://doi.org/10.1002/eji.201142250openalex-snapshot
Overexpression of ROR γt under control of the CD 2 promoter induces polyclonal plasmacytosis and autoantibody production in transgenic mice
inferred← citeshttps://doi.org/10.1002/eji.201344184openalex-snapshot
Interleukin 17 contributes to the chronicity of inflammatory diseases such as rheumatoid arthritis
inferred← citeshttps://doi.org/10.1002/eji.201344328openalex-snapshot
A pro‐inflammatory signalome is constitutively activated by C33Y mutant TNF receptor 1 in TNF receptor‐associated periodic syndrome (TRAPS)
inferred← citeshttps://doi.org/10.1002/eji.201545924openalex-snapshot
Pathogenic IL‐23 signaling is required to initiate GM‐CSF‐driven autoimmune myocarditis in mice
inferred← citeshttps://doi.org/10.1002/eji.201646565openalex-snapshot
CD11b regulates the Treg/Th17 balance in murine arthritis via IL‐6
inferred← citeshttps://doi.org/10.1002/glia.22307openalex-snapshot
Regulation of CCL20 expression in astrocytes by IL‐6 and IL‐17
inferred← citeshttps://doi.org/10.1002/glia.23530openalex-snapshot
MiR‐409‐3p and MiR‐1896 co‐operatively participate in IL‐17‐induced inflammatory cytokine production in astrocytes and pathogenesis of EAE mice via targeting SOCS3/STAT3 signaling
inferred← citeshttps://doi.org/10.1002/hep.25829openalex-snapshot
Deletion of Interleukin (IL)-12p35 Induces Liver Fibrosis in Dominant-Negative TGFβ Receptor Type II Mice
inferred← citeshttps://doi.org/10.1002/ibd.20894openalex-snapshot
Interleukin-23/Th17 pathways and inflammatory bowel disease
inferred← citeshttps://doi.org/10.1002/ibd.21476openalex-snapshot
IRF4 regulates IL-17A promoter activity and controls RORγt-dependent Th17 colitis in vivo
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Application prospects of cerebrospinal fluid DIA techniques in identifying key regulatory molecules for mental disorders in encephalitis
inferred← citeshttps://doi.org/10.1002/mc.22999openalex-snapshot
Interplay between bile acids and the gut microbiota promotes intestinal carcinogenesis
inferred← citeshttps://doi.org/10.1007/978-1-4419-9371-7_22openalex-snapshot
IL-17 and TH17 Cells in Human Rheumatoid Arthritis
inferred← citeshttps://doi.org/10.1007/978-1-4419-9371-7_23openalex-snapshot
The Role of the IL-23/TH17 Immune Pathway in the Pathogenesis of Arthritis
inferred← citeshttps://doi.org/10.1007/978-3-030-85161-3_9openalex-snapshot
Regulatory T Cells in SLE
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Endothelial Control of the Inflammatory Process
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inferred← citeshttps://doi.org/10.1007/978-4-431-54442-5_3openalex-snapshot
The Roles of IL-17A and IL-17F in Infection and Inflammatory Disorders
inferred← citeshttps://doi.org/10.1007/978-94-024-0921-5_7openalex-snapshot
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IRF4 selectively controls cytokine gene expression in chronic intestinal inflammation
inferred← citeshttps://doi.org/10.1007/s00005-013-0255-9openalex-snapshot
The Reverse-Direction Method Links Mass Experimental Data to Human Diseases
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IL-6 Contributes to the TGF-β1-Mediated Epithelial to Mesenchymal Transition in Human Salivary Gland Epithelial Cells
inferred← citeshttps://doi.org/10.1007/s00011-025-02081-wopenalex-snapshot
Bridging worlds: a narrative review of IL-17 at the crossroads of inflammation and thrombosis
inferred← citeshttps://doi.org/10.1007/s00210-017-1459-zopenalex-snapshot
Modulation of the IL-23/IL-17 axis by fenofibrate ameliorates the ovalbumin/lipopolysaccharide-induced airway inflammation and bronchial asthma in rats
inferred← citeshttps://doi.org/10.1007/s00262-017-1965-3openalex-snapshot
Murine Th17 cells utilize IL-2 receptor gamma chain cytokines but are resistant to cytokine withdrawal-induced apoptosis
inferred← citeshttps://doi.org/10.1007/s00281-009-0186-zopenalex-snapshot
Th17 cells in autoimmune demyelinating disease
inferred← citeshttps://doi.org/10.1007/s00281-009-0189-9openalex-snapshot
Th17 cytokines and arthritis
inferred← citeshttps://doi.org/10.1007/s00281-014-0442-8openalex-snapshot
Mechanisms of tissue damage in arthritis
inferred← citeshttps://doi.org/10.1007/s00281-020-00827-8openalex-snapshot
Control of immunity by glucocorticoids in health and disease
inferred← citeshttps://doi.org/10.1007/s00383-013-3421-6openalex-snapshot
Elevated Th17 cells accompanied by decreased regulatory T cells and cytokine environment in infants with biliary atresia
inferred← citeshttps://doi.org/10.1007/s00430-017-0527-9openalex-snapshot
Genotype-related variations in proinflammatory and regulatory cytokine levels in treated and treatment-naive HCV-infected patients
inferred← citeshttps://doi.org/10.1007/s00774-014-0565-yopenalex-snapshot
A significant induction of neutrophilic chemoattractants but not RANKL in synoviocytes stimulated with interleukin 17
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inferred← citeshttps://doi.org/10.1007/s10067-025-07433-9openalex-snapshot
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Electroacupuncture Reduces Inflammation but Not Bone Loss on Periodontitis in Arthritic Rats
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MicroRNA let-7a Ameliorates Con A-Induced Hepatitis by Inhibiting IL-6-Dependent Th17 Cell Differentiation
inferred← citeshttps://doi.org/10.1007/s11060-012-0981-6openalex-snapshot
The role of STAT3 activation in modulating the immune microenvironment of GBM
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Cell-Type-Specific Expression of STAT Transcription Factors in Tissue Samples from Patients with Lymphocytic Thyroiditis
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Autoimmune Arthritis
inferred← citeshttps://doi.org/10.1016/b978-0-12-800147-9.00006-6openalex-snapshot
Roles for Helper T Cell Lineage-Specifying Transcription Factors in Cellular Specialization
inferred← citeshttps://doi.org/10.1016/b978-0-12-800763-1.00006-3openalex-snapshot
Role of Cytokine-Mediated Crosstalk between T Cells and Nonimmune Cells in the Pathophysiology of Multiple Sclerosis
inferred← citeshttps://doi.org/10.1016/b978-0-12-801121-8.00002-6openalex-snapshot
Interleukin-1 Superfamily and Cancer
inferred← citeshttps://doi.org/10.1016/b978-0-12-801121-8.00008-7openalex-snapshot
Interleukin-17 Superfamily and Cancer
inferred← citeshttps://doi.org/10.1016/b978-0-12-805298-3.00005-0openalex-snapshot
Gateway Reflexes Are Stimulated by Neural Activations and Promote the Pathogenesis of Multiple Sclerosis Models
inferred← citeshttps://doi.org/10.1016/b978-0-323-77724-7.00010-3openalex-snapshot
Follicular Occlusion and Inflammation
inferred← citeshttps://doi.org/10.1016/j.ajpath.2013.07.019openalex-snapshot
IL-17A Synergistically Enhances Bile Acid–Induced Inflammation during Obstructive Cholestasis
inferred← citeshttps://doi.org/10.1016/j.arr.2025.102822openalex-snapshot
Osteoimmunology and aging: Mechanisms, implications, and therapeutic perspectives
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inferred← citeshttps://doi.org/10.1016/j.bbi.2016.03.003openalex-snapshot
Spinal activity of interleukin 6 mediates myelin basic protein-induced allodynia
inferred← citeshttps://doi.org/10.1016/j.bbrc.2016.06.049openalex-snapshot
IL-17A synergistically enhances TNFα-induced IL-6 and CCL20 production in 3T3-L1 adipocytes
inferred← citeshttps://doi.org/10.1016/j.bbrc.2017.05.166openalex-snapshot
Amelioration of adjuvant-induced arthritis in CCDC134-overexpressing transgenic mice
inferred← citeshttps://doi.org/10.1016/j.bbrc.2018.10.129openalex-snapshot
Correlation of spatio-temporal characteristics of intestinal inflammation with IL-17 in a rat model of hypoganglionosis
inferred← citeshttps://doi.org/10.1016/j.bioadv.2026.214793openalex-snapshot
Inflammation-induced cell-secreted migrasome promotes IL-6 expression in the recipient cells
inferred← citeshttps://doi.org/10.1016/j.biocel.2014.11.008openalex-snapshot
Arthritogenic T cells in autoimmune arthritis
inferred← citeshttps://doi.org/10.1016/j.biopha.2024.116256openalex-snapshot
Celastrol regulates psoriatic inflammation and autophagy by targeting IL-17A
inferred← citeshttps://doi.org/10.1016/j.brainresrev.2011.01.002openalex-snapshot
Interleukin-6, a mental cytokine
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Nitazoxanide protects against experimental ulcerative colitis through improving intestinal barrier and inhibiting inflammation
inferred← citeshttps://doi.org/10.1016/j.ccr.2014.03.014openalex-snapshot
Oncogenic Kras Activates a Hematopoietic-to-Epithelial IL-17 Signaling Axis in Preinvasive Pancreatic Neoplasia
inferred← citeshttps://doi.org/10.1016/j.cdnut.2024.104532openalex-snapshot
Berberine Inhibits Breast Cancer Stem Cell Development and Decreases Inflammation: Involvement of miRNAs and IL-6
inferred← citeshttps://doi.org/10.1016/j.cell.2011.01.011openalex-snapshot
IL-7 Engages Multiple Mechanisms to Overcome Chronic Viral Infection and Limit Organ Pathology
inferred← citeshttps://doi.org/10.1016/j.cell.2011.01.038openalex-snapshot
IL-7 Knocks the Socs Off Chronic Viral Infection
inferred← citeshttps://doi.org/10.1016/j.cell.2012.01.022openalex-snapshot
Regional Neural Activation Defines a Gateway for Autoreactive T Cells to Cross the Blood-Brain Barrier
inferred← citeshttps://doi.org/10.1016/j.celrep.2013.01.028openalex-snapshot
Disease-Association Analysis of an Inflammation-Related Feedback Loop
inferred← citeshttps://doi.org/10.1016/j.celrep.2015.06.050openalex-snapshot
An IκB Kinase-Regulated Feedforward Circuit Prolongs Inflammation
inferred← citeshttps://doi.org/10.1016/j.celrep.2018.11.083openalex-snapshot
Rab4b Deficiency in T Cells Promotes Adipose Treg/Th17 Imbalance, Adipose Tissue Dysfunction, and Insulin Resistance
inferred← citeshttps://doi.org/10.1016/j.cjca.2019.06.021openalex-snapshot
Effects of Interleukin 17A Inhibition on Myocardial Deformation and Vascular Function in Psoriasis
inferred← citeshttps://doi.org/10.1016/j.clim.2012.08.009openalex-snapshot
Transglutaminase 2 exacerbates experimental autoimmune encephalomyelitis through positive regulation of encephalitogenic T cell differentiation and inflammation
inferred← citeshttps://doi.org/10.1016/j.clim.2018.08.006openalex-snapshot
IL-11 antagonist suppresses Th17 cell-mediated neuroinflammation and demyelination in a mouse model of relapsing-remitting multiple sclerosis
inferred← citeshttps://doi.org/10.1016/j.clim.2020.108342openalex-snapshot
Longitudinal relationships between rheumatoid factor and cytokine expression by immunostimulated peripheral blood lymphocytes from patients with rheumatoid arthritis: New insights into B-cell activation
inferred← citeshttps://doi.org/10.1016/j.coi.2026.102785openalex-snapshot
New learnings from the molecular pathology of the synovial tissue in rheumatoid arthritis: from pathogenesis to therapeutic targeting toward precision medicine
inferred← citeshttps://doi.org/10.1016/j.csbj.2023.10.058openalex-snapshot
A glance through the effects of CD4 + T cells, CD8 + T cells, and cytokines on Alzheimer's disease
inferred← citeshttps://doi.org/10.1016/j.cyto.2012.05.027openalex-snapshot
Transcriptional regulation of IL-17A and other inflammatory markers during the development of soybean meal-induced enteropathy in the distal intestine of Atlantic salmon (Salmo salar L.)
inferred← citeshttps://doi.org/10.1016/j.cyto.2015.02.002openalex-snapshot
The role and modulation of CCR6+ Th17 cell populations in rheumatoid arthritis
inferred← citeshttps://doi.org/10.1016/j.cyto.2015.05.007openalex-snapshot
The role of serum IL-17 and IL-6 as biomarkers of disease activity and predictors of remission in patients with lupus nephritis
inferred← citeshttps://doi.org/10.1016/j.cyto.2017.12.014openalex-snapshot
Interleukin-7 augments CD8+ T cells function and promotes viral clearance in chronic hepatitis C virus infection
inferred← citeshttps://doi.org/10.1016/j.cyto.2018.01.025openalex-snapshot
MERS-CoV infection in humans is associated with a pro-inflammatory Th1 and Th17 cytokine profile
inferred← citeshttps://doi.org/10.1016/j.cyto.2021.155650openalex-snapshot
Emerging roles for IL-6 family cytokines as positive and negative regulators of ectopic lymphoid structures
inferred← citeshttps://doi.org/10.1016/j.cytogfr.2020.12.004openalex-snapshot
The determinant role of IL-6 in the establishment of inflammation leading to spontaneous preterm birth
inferred← citeshttps://doi.org/10.1016/j.cytogfr.2024.07.007openalex-snapshot
Inflammatory mechanisms of preterm labor and emerging anti-inflammatory interventions
inferred← citeshttps://doi.org/10.1016/j.drudis.2016.03.009openalex-snapshot
Molecular basis for cytokine biomarkers of complex 3D microtissue physiology in vitro
inferred← citeshttps://doi.org/10.1016/j.drudis.2021.06.017openalex-snapshot
Blocking the inflammasome: A novel approach to treat uveitis
inferred← citeshttps://doi.org/10.1016/j.ejim.2010.05.010openalex-snapshot
A 3-factor epistatic model predicts digital ulcers in Italian scleroderma patients
inferred← citeshttps://doi.org/10.1016/j.ejphar.2020.173294openalex-snapshot
6-Gingerol attenuates microglia-mediated neuroinflammation and ischemic brain injuries through Akt-mTOR-STAT3 signaling pathway
inferred← citeshttps://doi.org/10.1016/j.febslet.2011.03.064openalex-snapshot
Cytokines and effector T cell subsets causing autoimmune CNS disease
inferred← citeshttps://doi.org/10.1016/j.febslet.2011.04.069openalex-snapshot
Arthritis in space and time – To boldly go!
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2014.04.028openalex-snapshot
The glutaredoxin/S-glutathionylation axis regulates interleukin-17A-induced proinflammatory responses in lung epithelial cells in association with S-glutathionylation of nuclear factor κB family proteins
inferred← citeshttps://doi.org/10.1016/j.fsi.2016.01.042openalex-snapshot
Cloning and characterization of two duplicated interleukin-17A/F2 genes in common carp ( Cyprinus carpio L.): Transcripts expression and bioactivity of recombinant IL-17A/F2
inferred← citeshttps://doi.org/10.1016/j.humimm.2009.01.010openalex-snapshot
The IL6 -174G/C polymorphism is associated with celiac disease susceptibility in girls
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2025.148270openalex-snapshot
Role of lncRNAs H19, KCNQ1OT1 and SRA in relation to peroxisome proliferator-activated receptor gamma in the occurrence and progression of non-alcoholic fatty pancreas disease in obese and non-obese Egyptian patients
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2018.05.058openalex-snapshot
A novel fusion protein attenuates collagen–induced arthritis by targeting interleukin 17A and tumor necrosis factor α
inferred← citeshttps://doi.org/10.1016/j.imbio.2012.05.023openalex-snapshot
Thymic peptides restrain the inflammatory response in mice with experimental autoimmune encephalomyelitis
inferred← citeshttps://doi.org/10.1016/j.imlet.2012.10.011openalex-snapshot
IL-17 promoted metastasis of non-small-cell lung cancer cells
inferred← citeshttps://doi.org/10.1016/j.imlet.2017.09.007openalex-snapshot
Is there a role for IL-17 in the pathogenesis of systemic sclerosis?
inferred← citeshttps://doi.org/10.1016/j.immuni.2009.01.007openalex-snapshot
Hepatic Interleukin-7 Expression Regulates T Cell Responses
inferred← citeshttps://doi.org/10.1016/j.immuni.2010.09.004openalex-snapshot
Even Neurons Are Excited by Th17 Cells
inferred← citeshttps://doi.org/10.1016/j.immuni.2011.02.012openalex-snapshot
Functional Specialization of Interleukin-17 Family Members
inferred← citeshttps://doi.org/10.1016/j.immuni.2012.01.005openalex-snapshot
Notch Activation by the Metalloproteinase ADAM17 Regulates Myeloproliferation and Atopic Barrier Immunity by Suppressing Epithelial Cytokine Synthesis
inferred← citeshttps://doi.org/10.1016/j.immuni.2017.01.004openalex-snapshot
Autocrine Loop Involving IL-6 Family Member LIF, LIF Receptor, and STAT4 Drives Sustained Fibroblast Production of Inflammatory Mediators
inferred← citeshttps://doi.org/10.1016/j.immuni.2019.03.027openalex-snapshot
Pleiotropy and Specificity: Insights from the Interleukin 6 Family of Cytokines
inferred← citeshttps://doi.org/10.1016/j.intimp.2013.07.021openalex-snapshot
Proton pump inhibitor selectively suppresses proliferation and restores the chemosensitivity of gastric cancer cells by inhibiting STAT3 signaling pathway
inferred← citeshttps://doi.org/10.1016/j.intimp.2013.10.009openalex-snapshot
Administration of mycobacterial Ag85A and IL-17A fusion protein attenuates airway inflammation in a murine model of asthma
inferred← citeshttps://doi.org/10.1016/j.intimp.2015.01.021openalex-snapshot
Modulation of inflammatory response in mice with severe autoimmune disease by thymic peptide thymulin and an inhibitor of NF-kappaB signalling
inferred← citeshttps://doi.org/10.1016/j.intimp.2015.03.037openalex-snapshot
The role of chemokines in adjusting the balance between CD4+ effector T cell subsets and FOXp3-negative regulatory T cells
inferred← citeshttps://doi.org/10.1016/j.intimp.2016.12.013openalex-snapshot
Periplocoside A ameliorated type II collagen-induced arthritis in mice via regulation of the balance of Th17/Treg cells
inferred← citeshttps://doi.org/10.1016/j.intimp.2019.03.040openalex-snapshot
α-Difluoromethylornithine suppresses inflammatory arthritis by impairing myeloid-derived suppressor cells
inferred← citeshttps://doi.org/10.1016/j.intimp.2020.107331openalex-snapshot
The role of Th17 cells in viral infections
inferred← citeshttps://doi.org/10.1016/j.intimp.2022.109095openalex-snapshot
Advance in bone destruction participated by JAK/STAT in rheumatoid arthritis and therapeutic effect of JAK/STAT inhibitors
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.112755openalex-snapshot
De novo mutations promote inflammation in children with STAT3 gain-of-function syndrome by affecting IL-1β expression
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.113709openalex-snapshot
Ankylosing spondylitis: From pathogenesis to therapy
inferred← citeshttps://doi.org/10.1016/j.it.2009.09.009openalex-snapshot
Suppressors of cytokine signaling (SOCS) in T cell differentiation, maturation, and function
inferred← citeshttps://doi.org/10.1016/j.jacc.2014.11.054openalex-snapshot
ApoB-100–Related Peptide Vaccine Protects Against Angiotensin II–Induced Aortic Aneurysm Formation and Rupture
inferred← citeshttps://doi.org/10.1016/j.jaci.2021.12.769openalex-snapshot
TH17 cells and corticosteroid insensitivity in severe asthma
inferred← citeshttps://doi.org/10.1016/j.jbiosc.2026.08.001openalex-snapshot
Proteomic analysis of migrasomes derived from IL-6 amplifier-induced human breast cancer cells
inferred← citeshttps://doi.org/10.1016/j.jcyt.2017.04.001openalex-snapshot
Monocyte lineage–derived IL-6 does not affect chimeric antigen receptor T-cell function
inferred← citeshttps://doi.org/10.1016/j.jdin.2020.05.005openalex-snapshot
Hidradenitis suppurativa is an autoinflammatory keratinization disease: A review of the clinical, histologic, and molecular evidence
inferred← citeshttps://doi.org/10.1016/j.jep.2023.117290openalex-snapshot
Interpretation of the anti-influenza active ingredients and potential mechanisms of Ge Gen Decoction based on spectrum-effect relationships and network analysis
inferred← citeshttps://doi.org/10.1016/j.jid.2018.07.044openalex-snapshot
NEDD4 Is Involved in Inflammation Development during Keloid Formation
inferred← citeshttps://doi.org/10.1016/j.jneuroim.2009.02.013openalex-snapshot
Demyelination caused by the copper chelator cuprizone halts T cell mediated autoimmune neuroinflammation
inferred← citeshttps://doi.org/10.1016/j.jneuroim.2016.01.014openalex-snapshot
Metformin ameliorates the development of experimental autoimmune encephalomyelitis by regulating T helper 17 and regulatory T cells in mice
inferred← citeshttps://doi.org/10.1016/j.jneuroim.2016.05.023openalex-snapshot
Distinct intrathecal interleukin-17/interleukin-6 activation in anti-N-methyl-d-aspartate receptor encephalitis
inferred← citeshttps://doi.org/10.1016/j.jri.2009.12.003openalex-snapshot
Increased prevalence of T helper 17 (Th17) cells in peripheral blood and decidua in unexplained recurrent spontaneous abortion patients
inferred← citeshttps://doi.org/10.1016/j.jri.2012.05.004openalex-snapshot
Interleukin-6 in pregnancy and gestational disorders
inferred← citeshttps://doi.org/10.1016/j.jtbi.2012.09.017openalex-snapshot
The role of positive feedback loops involving anti-dsDNA and anti–anti-dsDNA antibodies in autoimmune glomerulonephritis
inferred← citeshttps://doi.org/10.1016/j.lfs.2022.121119openalex-snapshot
Vismodegib, a sonic hedgehog signalling blockade, ameliorates ovalbumin and ovalbumin/lipopolysaccharide-induced airway inflammation and asthma phenotypical models
inferred← citeshttps://doi.org/10.1016/j.lfs.2023.121755openalex-snapshot
IL-17A-targeting fenofibrate attenuates inflammation in psoriasis by inducing autophagy
inferred← citeshttps://doi.org/10.1016/j.matbio.2023.08.004openalex-snapshot
Autocrine IL-6 drives cell and extracellular matrix anisotropy in scar fibroblasts
inferred← citeshttps://doi.org/10.1016/j.mehy.2013.08.033openalex-snapshot
Pathological niche environment transforms dermal stem cells to keloid stem cells: A hypothesis of keloid formation and development
inferred← citeshttps://doi.org/10.1016/j.micpath.2019.103903openalex-snapshot
Impact of simultaneous neutralization of IL-17A and treatment with recombinant IL-2 on Th17-Treg cell population in S.aureus induced septic arthritis
inferred← citeshttps://doi.org/10.1016/j.molimm.2010.06.007openalex-snapshot
Triptolide ameliorates IL-10-deficient mice colitis by mechanisms involving suppression of IL-6/STAT3 signaling pathway and down-regulation of IL-17
inferred← citeshttps://doi.org/10.1016/j.nbd.2023.106005openalex-snapshot
Neuro-immune crosstalk in depressive symptoms of multiple sclerosis
inferred← citeshttps://doi.org/10.1016/j.nbscr.2022.100079openalex-snapshot
Sex differences in the diathetic effects of shift work schedules on circulating cytokine levels and pathological outcomes of ischemic stroke during middle age
inferred← citeshttps://doi.org/10.1016/j.neuint.2018.06.007openalex-snapshot
Cell- and stage-specific localization of galectin-3, a β-galactoside-binding lectin, in a mouse model of experimental autoimmune encephalomyelitis
inferred← citeshttps://doi.org/10.1016/j.neuint.2018.09.011openalex-snapshot
Gateway reflex: Local neuroimmune interactions that regulate blood vessels
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2024.06.009openalex-snapshot
JAK2/STAT3 Pathway Inhibition by AG490 Ameliorates Experimental Autoimmune Encephalomyelitis via Regulation of Th17 Cells and Autophagy
inferred← citeshttps://doi.org/10.1016/j.oraloncology.2022.106270openalex-snapshot
Tumor-derived exosomes elicit cancer-associated fibroblasts shaping inflammatory tumor microenvironment in head and neck squamous cell carcinoma
inferred← citeshttps://doi.org/10.1016/j.pathol.2017.01.003openalex-snapshot
The role of interleukin-17A in the pathogenesis of kidney diseases
inferred← citeshttps://doi.org/10.1016/j.phrs.2020.104946openalex-snapshot
Biochemical indicators of coronavirus disease 2019 exacerbation and the clinical implications
inferred← citeshttps://doi.org/10.1016/j.phrs.2020.105323openalex-snapshot
Dysregulation of leukocyte trafficking in ageing: Causal factors and possible corrective therapies
inferred← citeshttps://doi.org/10.1016/j.preteyeres.2020.100866openalex-snapshot
Activation of the interleukin-23/interleukin-17 signalling pathway in autoinflammatory and autoimmune uveitis
inferred← citeshttps://doi.org/10.1016/j.redox.2021.101987openalex-snapshot
Electrophilic nitro-fatty acids suppress psoriasiform dermatitis: STAT3 inhibition as a contributory mechanism
inferred← citeshttps://doi.org/10.1016/j.reuma.2024.10.006openalex-snapshot
Investigating potential biomarkers and therapeutic targets for patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) through the utilization of cytokine profiling
inferred← citeshttps://doi.org/10.1016/j.reumae.2025.101805openalex-snapshot
Investigating potential biomarkers and therapeutic targets for patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) through the utilization of cytokine profiling
inferred← citeshttps://doi.org/10.1016/j.tins.2026.07.002openalex-snapshot
Interleukin-6 trans-signalling as a selectively targetable driver of neurodegeneration
inferred← citeshttps://doi.org/10.1016/j.transproceed.2011.12.032openalex-snapshot
Immunology Mini-review: The Basics of TH17 and Interleukin-6 in Transplantation
inferred← citeshttps://doi.org/10.1016/j.trsl.2016.12.003openalex-snapshot
Tocilizumab improves the proatherothrombotic profile of rheumatoid arthritis patients modulating endothelial dysfunction, NETosis, and inflammation
inferred← citeshttps://doi.org/10.1016/j.trsl.2026.05.004openalex-snapshot
Targeted protein degradation in inflammatory bone diseases: Mechanistic basis and therapeutic opportunities
inferred← citeshttps://doi.org/10.1016/j.vetimm.2013.09.017openalex-snapshot
Markedly increased expression of interleukin-8 in the colorectal mucosa of inflammatory colorectal polyps in miniature dachshunds
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2025.06.002openalex-snapshot
Mechanisms underlying atrial fibrillation in chronic kidney disease
inferred← citeshttps://doi.org/10.1016/s0140-6736(24)01750-1openalex-snapshot
IL-23 inhibition for chronic inflammatory disease
inferred← citeshttps://doi.org/10.1016/s0213-9626(09)70025-3openalex-snapshot
The Th17 lineage: Answers to some immunological questions
inferred← citeshttps://doi.org/10.1021/acs.accounts.6c00139openalex-snapshot
Targeting Fibroblast Activation Protein for Precision Medicine
inferred← citeshttps://doi.org/10.1021/acs.est.7b05015openalex-snapshot
Differential Health Effects of Constant versus Intermittent Exposure to Formaldehyde in Mice: Implications for Building Ventilation Strategies
inferred← citeshttps://doi.org/10.1038/cmi.2017.82openalex-snapshot
MicroRNA in vivo precipitation identifies miR-151-3p as a computational unpredictable miRNA to target Stat3 and inhibits innate IL-6 production
inferred← citeshttps://doi.org/10.1038/icb.2010.168openalex-snapshot
Homeostatic defects in interleukin 18‐deficient mice contribute to protection against the lethal effects of endotoxin
inferred← citeshttps://doi.org/10.1038/icb.2011.59openalex-snapshot
Critical role of interleukin‐17/interleukin‐17 receptor axis in mediating Con A‐induced hepatitis
inferred← citeshttps://doi.org/10.1038/icb.2014.104openalex-snapshot
Leukotrienes induce the migration of Th17 cells
inferred← citeshttps://doi.org/10.1038/jid.2013.404openalex-snapshot
IL-6 Regulates Neutrophil Microabscess Formation in IL-17A-Driven Psoriasiform Lesions
inferred← citeshttps://doi.org/10.1038/jid.2013.500openalex-snapshot
Periostin Controls Keratinocyte Proliferation and Differentiation by Interacting with the Paracrine IL-1α/IL-6 Loop
inferred← citeshttps://doi.org/10.1038/jid.2014.426openalex-snapshot
Psoriatic Inflammation Facilitates the Onset of Arthritis in a Mouse Model
inferred← citeshttps://doi.org/10.1038/ni.2633openalex-snapshot
The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation
inferred← citeshttps://doi.org/10.1038/ni.3742openalex-snapshot
Interleukin 17 is a chief orchestrator of immunity
inferred← citeshttps://doi.org/10.1038/nm.1953openalex-snapshot
Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies
inferred← citeshttps://doi.org/10.1038/nrc2734openalex-snapshot
STATs in cancer inflammation and immunity: a leading role for STAT3
inferred← citeshttps://doi.org/10.1038/nrrheum.2009.179openalex-snapshot
IL-17 as a future therapeutic target for rheumatoid arthritis
inferred← citeshttps://doi.org/10.1038/nrrheum.2015.53openalex-snapshot
The IL-23–IL-17 axis in inflammatory arthritis
inferred← citeshttps://doi.org/10.1038/s41419-020-02891-2openalex-snapshot
Small molecules targeting RORγt inhibit autoimmune disease by suppressing Th17 cell differentiation
inferred← citeshttps://doi.org/10.1038/s41467-019-11606-xopenalex-snapshot
Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions
inferred← citeshttps://doi.org/10.1038/s41467-025-62919-zopenalex-snapshot
The pathogenicity and multi-organ proteomic profiles of Mpox virus infection in SIVmac239-infected rhesus macaques
inferred← citeshttps://doi.org/10.1038/s41577-019-0178-8openalex-snapshot
Osteoimmunology: evolving concepts in bone–immune interactions in health and disease
inferred← citeshttps://doi.org/10.1038/s41584-022-00793-5openalex-snapshot
Mechanisms of joint destruction in rheumatoid arthritis — immune cell–fibroblast–bone interactions
inferred← citeshttps://doi.org/10.1038/s41584-025-01259-0openalex-snapshot
Fibroblasts in immune responses, inflammatory diseases and therapeutic implications
inferred← citeshttps://doi.org/10.1038/s41598-017-14027-2openalex-snapshot
Cell-penetrating interactomic inhibition of nuclear factor-kappa B in a mouse model of postoperative cognitive dysfunction
inferred← citeshttps://doi.org/10.1038/s41598-018-34173-5openalex-snapshot
IL-6, IL-17 and Stat3 are required for auto-inflammatory syndrome development in mouse
inferred← citeshttps://doi.org/10.1038/s41598-019-38811-4openalex-snapshot
Interleukin 17A promotes diabetic kidney injury
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