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An integrated strategy to explore the potential role of melatonin against copper-induced adrenaline toxicity in rat cardiomyocytes: Insights into oxidative stress, inflammation, and apoptosis

https://doi.org/10.1016/j.intimp.2023.110301
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Outgoing claims: the papers this work cites, builds on, or argues with.

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Trypan Blue Exclusion Test of Cell Viability
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Toxicology update: the cardiotoxicity of the oxidative stress metabolites of catecholamines (aminochromes)
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Microplate Superoxide Dismutase Assay Employing a Nonenzymatic Superoxide Generator
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Emerging roles of thioredoxin cycle enzymes in the central nervous system
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Cardiac remodeling, apoptosis-related process (Bax, Bcl-2), and their ratio (Bax/Bcl-2) in cardiomyocytes of diabetic rats after combined exercise training and taurine supplementation
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Melatonin protected cardiac microvascular endothelial cells against oxidative stress injury via suppression of IP3R-[Ca2+]c/VDAC-[Ca2+]m axis by activation of MAPK/ERK signaling pathway
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Acidic pH enables caeruloplasmin to catalyse the modification of low‐density lipoprotein
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Stimulatory effect of amp on the copper ion dependent oxidation of adrenaline to adrenochrome
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Tissue acidosis in myocardial hypoxia
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Cupric ion/ascorbate/hydrogen peroxide-induced DNA damage: DNA-bound copper ion primarily induces base modifications
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Cellular and Molecular Pathobiology of Cardiovascular Disease
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Adrenergic receptors and cardiovascular effects of catecholamines
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Melatonin fine-tunes intracellular calcium signals and eliminates myocardial damage through the IP3R/MCU pathways in cardiorenal syndrome type 3
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Possible pathophysiology of heart failure in obesity: Cardiac apoptosis
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Arsenic-induced immunomodulatory effects disorient the survival-death interface by stabilizing the Hsp90/Beclin1 interaction
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Molecular mechanism activating nrf2–keap1 pathway in regulation of adaptive response to electrophiles
inferredcites →https://doi.org/10.1016/j.heliyon.2021.e06474openalex-snapshot
Melatonin protects the heart and pancreas by improving glucose homeostasis, oxidative stress, inflammation and apoptosis in T2DM-induced rats
inferredcites →https://doi.org/10.1016/j.ijcard.2017.11.007openalex-snapshot
Estradiol protection against toxic effects of catecholamine on electrical properties in human-induced pluripotent stem cell derived cardiomyocytes
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Oleic acid protects against cadmium induced cardiac and hepatic tissue injury in male Wistar rats: A mechanistic study
inferredcites →https://doi.org/10.1016/j.lfs.2022.121290openalex-snapshot
Arsenic-induced differential inflammatory responses in mouse thymus involves NF-κB/STAT-3 disruption, Treg bias and autophagy activation
inferredcites →https://doi.org/10.1016/j.neuro.2016.09.002openalex-snapshot
Melatonin protects against oxygen and glucose deprivation by decreasing extracellular glutamate and Nox-derived ROS in rat hippocampal slices
inferredcites →https://doi.org/10.1016/j.rec.2011.10.011openalex-snapshot
Melatonin and Cardiovascular Disease: Myth or Reality?
inferredcites →https://doi.org/10.1016/j.redox.2020.101777openalex-snapshot
Phosphoglycerate mutase 5 exacerbates cardiac ischemia-reperfusion injury through disrupting mitochondrial quality control
inferredcites →https://doi.org/10.1016/s0006-291x(03)00667-3openalex-snapshot
Copper-induced oxidation of epinephrine: protective effect of d-DAHK, a synthetic analogue of the high affinity copper binding site of human albumin
inferredcites →https://doi.org/10.1016/s0009-2797(00)00156-3openalex-snapshot
DNA damage induced by catechol derivatives
inferredcites →https://doi.org/10.1016/s0021-9258(18)97361-8openalex-snapshot
Studies on Avian Xanthine Dehydrogenases
inferredcites →https://doi.org/10.1016/s0022-2828(85)80134-6openalex-snapshot
Catecholamine-induced myocardial cell damage: Catecholamines or adrenochrome
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Autoxidation versus Covalent Binding of Quinones as the Mechanism of Toxicity of Dopamine, 6-Hydroxydopamine, and Related Compounds toward C1300 Neuroblastoma Cells in Vitro
inferredcites →https://doi.org/10.1016/s0076-6879(78)52032-6openalex-snapshot
[30] Microsomal lipid peroxidation
inferredcites →https://doi.org/10.1016/s0076-6879(84)05016-3openalex-snapshot
[13] Catalase in vitro
inferredcites →https://doi.org/10.1016/s0891-5849(96)00547-3openalex-snapshot
Hydroxyl Radical is the Major Causative Factor in Stress-Induced Gastric Ulceration
inferredcites →https://doi.org/10.1016/s0891-5849(97)00281-5openalex-snapshot
Oxidative Inactivation of Gastric Peroxidase by Site-Specific Generation of Hydroxyl Radical and Its Role in Stress-Induced Gastric Ulceration
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Simple and Novel Screening Assay of Natural Antioxidants for Cu(II) Ion/Adrenaline-Mediated Oxidation of N-Terminal Amyloid β by Liquid Chromatography/Mass Spectrometry
inferredcites →https://doi.org/10.1021/tx7000916openalex-snapshot
Oxidation Process of Adrenaline in Freshly Isolated Rat Cardiomyocytes: Formation of Adrenochrome, Quinoproteins, and GSH Adduct
inferredcites →https://doi.org/10.1034/j.1600-079x.2003.00051.xopenalex-snapshot
The melatonin receptor subtype MT2 is present in the human cardiovascular system
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Coordinate and redox interactions of epinephrine with ferric and ferrous iron at physiological pH
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The effect of age and sex on glutathione reductase and glutathione peroxidase activities and on aerobic glutathione oxidation in rat liver homogenates
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Inactivation of catecholamines by superoxide gives new insights on the pathogenesis of septic shock
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Positive and Negative Regulation of NF-κB by COX-2
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Trypanosoma cruzi Induces the Reactive Oxygen Species-PARP-1-RelA Pathway for Up-regulation of Cytokine Expression in Cardiomyocytes
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Adrenaline stimulates H2O2generation in liver via NADPH oxidase
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Perioperative bradycardia and asystole: relationship to vasovagal syncope and the Bezold–Jarisch reflex
inferredcites →https://doi.org/10.1097/00024382-199510000-00007openalex-snapshot
SUSTAINED ELEVATION IN CIRCULATING CATECHOLAMINE LEVELS DURING POLYMICROBIAL SEPSIS
inferredcites →https://doi.org/10.1097/mol.0000000000000314openalex-snapshot
Effects of melatonin on cardiovascular diseases: progress in the past year
inferredcites →https://doi.org/10.1097/pcc.0000000000001448openalex-snapshot
Low-Dose Epinephrine Boluses for Acute Hypotension in the PICU*
inferredcites →https://doi.org/10.1111/imcb.12227openalex-snapshot
Fluoxetine triggers selective apoptosis in inflammation‐induced proliferating (Ki‐67high) thymocytes
inferredcites →https://doi.org/10.1111/j.1600-079x.2004.00118.xopenalex-snapshot
Melatonin protects against piroxicam‐induced gastric ulceration
inferredcites →https://doi.org/10.1111/j.1600-079x.2006.00407.xopenalex-snapshot
One molecule, many derivatives: A never‐ending interaction of melatonin with reactive oxygen and nitrogen species?
inferredcites →https://doi.org/10.1111/j.1600-079x.2012.00984.xopenalex-snapshot
EXPRESSION OF CONCERN: Melatonin protects against isoproterenol‐induced alterations in cardiac mitochondrial energy‐metabolizing enzymes, apoptotic proteins, and assists in complete recovery from myocardial injury in rats
inferredcites →https://doi.org/10.1111/j.1600-079x.2012.01014.xopenalex-snapshot
A review of the molecular aspects of melatonin’s anti‐inflammatory actions: recent insights and new perspectives
inferredcites →https://doi.org/10.1111/j.1742-1241.2006.01191.xopenalex-snapshot
Melatonin: therapeutic and clinical utilization
inferredcites →https://doi.org/10.1111/joim.13189openalex-snapshot
Abnormal thyroid function is common in takotsubo syndrome and depends on two distinct mechanisms: results of a multicentre observational study
inferredcites →https://doi.org/10.1111/jpi.12413openalex-snapshot
Melatonin protects cardiac microvasculature against ischemia/reperfusion injury via suppression of mitochondrial fission‐ VDAC 1‐ HK 2‐ mPTP ‐mitophagy axis
inferredcites →https://doi.org/10.1111/jpi.12450openalex-snapshot
RETRACTED: Effects of melatonin on fatty liver disease: The role of NR 4A1/ DNA ‐ PK cs/p53 pathway, mitochondrial fission, and mitophagy
inferredcites →https://doi.org/10.1142/4635openalex-snapshot
Clinical Biochemistry: Techniques and Instrumentation
inferredcites →https://doi.org/10.1146/annurev-publhealth-031912-114452openalex-snapshot
Stress and Cardiovascular Disease: An Update on Current Knowledge
inferredcites →https://doi.org/10.1161/circresaha.113.302095openalex-snapshot
Cardiac Metabolism and its Interactions With Contraction, Growth, and Survival of Cardiomyocytes
inferredcites →https://doi.org/10.1161/circresaha.116.309202openalex-snapshot
A Simplified, Langendorff-Free Method for Concomitant Isolation of Viable Cardiac Myocytes and Nonmyocytes From the Adult Mouse Heart
inferredcites →https://doi.org/10.1164/ajrccm.164.1.2008090openalex-snapshot
The Effect of Nebulized Epinephrine on Respiratory Mechanics and Gas Exchange in Bronchiolitis
inferredcites →https://doi.org/10.1186/1939-4551-1-s2-s18openalex-snapshot
Epinephrine: The Drug of Choice for Anaphylaxis--A Statement of the World Allergy Organization
inferredcites →https://doi.org/10.1210/er.2018-00084openalex-snapshot
Melatonin as a Hormone: New Physiological and Clinical Insights
inferredcites →https://doi.org/10.21037/atm.2016.05.19openalex-snapshot
An historical approach to the diagnostic biomarkers of acute coronary syndrome
inferredcites →https://doi.org/10.2174/15701611113119990003openalex-snapshot
Cardiac Oxidative Stress and Inflammatory Cytokines Response after Myocardial Infarction
inferredcites →https://doi.org/10.2298/avb1203151gopenalex-snapshot
Chronic physical stress changes gene expression of catecholamine biosynthetic enzymes in the adrenal medulla of adult rats
inferredcites →https://doi.org/10.3109/07853890903485748openalex-snapshot
Beneficial effects of melatonin in cardiovascular disease
inferredcites →https://doi.org/10.32794/mr11250007openalex-snapshot
Adrenaline induced disruption of endogenous melatoninergic system, antioxidant and inflammatory responses in the gastrointestinal tissues of male Wistar rat: an in vitro study
inferredcites →https://doi.org/10.32794/mr11250074openalex-snapshot
Amelioration of adrenaline induced oxidative gastrointestinal damages in rat by melatonin through SIRT1-NFκB and PGC1α-AMPKα cascades
inferredcites →https://doi.org/10.32794/mr11250080openalex-snapshot
Multiple strategies of melatonin protecting against cardiovascular injury related to inflammation: A comprehensive overview
inferredcites →https://doi.org/10.32794/mr11250097openalex-snapshot
Melatonin as a prospective metabolic regulator in pathologically altered cardiac energy homeostasis
inferredcites →https://doi.org/10.3390/diseases9020030openalex-snapshot
Potential Effects of Melatonin and Micronutrients on Mitochondrial Dysfunction during a Cytokine Storm Typical of Oxidative/Inflammatory Diseases
inferredcites →https://doi.org/10.3390/ijms17122124openalex-snapshot
Melatonin: A Mitochondrial Targeting Molecule Involving Mitochondrial Protection and Dynamics
inferredcites →https://doi.org/10.3390/ijms23158507openalex-snapshot
Functional Characterization of Human Induced Pluripotent Stem Cell-Derived Endothelial Cells
inferredcites →https://doi.org/10.4038/slja.v21i2.4744openalex-snapshot
Epinephrine toxicity : An avoidable fatal complication due to iatrogenic overdose
inferredcites →https://doi.org/10.4103/2230-8210.77573openalex-snapshot
Stress and hormones
inferredcites →https://doi.org/10.5935/abc.20180008openalex-snapshot
Melatonin-Induced Protective Effects on Cardiomyocytes Against Reperfusion Injury Partly Through Modulation of IP3R and SERCA2a Via Activation of ERK1

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inferred← citeshttps://doi.org/10.2139/ssrn.4536435openalex-extracted
Bacillus Smithii Xy1 Alleviates Copper-Induced Oxidative Stress and Accelerated Senescence Through Foxo Signaling Pathway
inferred← citeshttps://doi.org/10.1002/jbt.70194openalex-snapshot
Mitochondrial Quality Control and Melatonin: A Strategy Against Myocardial Injury
inferred← citeshttps://doi.org/10.1007/s10495-024-02054-0openalex-snapshot
Arsenic unsettles the cerebellar balance between neurodegeneration and neurogenesis: reversal by folic acid
inferred← citeshttps://doi.org/10.1016/j.bbadis.2024.167313openalex-snapshot
Metformin instigates cellular autophagy to ameliorate high-fat diet-induced pancreatic inflammation and fibrosis/EMT in mice
inferred← citeshttps://doi.org/10.4330/wjc.v18.i2.113358openalex-snapshot
Melatonin regulates Sirt1/Nrf2/GPX4 pathway to inhibit ferroptosis and alleviate myocardial injury caused by sepsis
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