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JAK2V617F-Mediated Clonal Hematopoiesis Accelerates Pathological Remodeling in Murine Heart Failure
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1001/jamacardio.2018.3965openalex-snapshot
Association of Mutations Contributing to Clonal Hematopoiesis With Prognosis in Chronic Ischemic Heart Failure
inferredcites →https://doi.org/10.1001/jamaoncol.2015.89openalex-snapshot
Myeloproliferative Neoplasms
inferredcites →https://doi.org/10.1002/gene.10161openalex-snapshot
vavCre Transgenic mice: A tool for mutagenesis in hematopoietic and endothelial lineages
inferredcites →https://doi.org/10.1016/j.ccr.2010.05.015openalex-snapshot
Physiological Jak2V617F Expression Causes a Lethal Myeloproliferative Neoplasm with Differential Effects on Hematopoietic Stem and Progenitor Cells
inferredcites →https://doi.org/10.1016/j.cell.2013.08.007openalex-snapshot
Clonal Analysis Unveils Self-Renewing Lineage-Restricted Progenitors Generated Directly from Hematopoietic Stem Cells
inferredcites →https://doi.org/10.1016/j.jacbts.2017.12.006openalex-snapshot
CCR2+ Monocyte-Derived Infiltrating Macrophages Are Required for Adverse Cardiac Remodeling During Pressure Overload
inferredcites →https://doi.org/10.1016/j.jacc.2017.09.028openalex-snapshot
Interleukin-1 Beta as a Target for Atherosclerosis Therapy
inferredcites →https://doi.org/10.1016/j.jacc.2017.12.037openalex-snapshot
Tet2-Mediated Clonal Hematopoiesis Accelerates Heart Failure Through a Mechanism Involving the IL-1β/NLRP3 Inflammasome
inferredcites →https://doi.org/10.1016/j.stem.2017.07.010openalex-snapshot
Therapy-Related Clonal Hematopoiesis in Patients with Non-hematologic Cancers Is Common and Associated with Adverse Clinical Outcomes
inferredcites →https://doi.org/10.1016/j.stem.2018.04.003openalex-snapshot
Causes and Consequences of Hematopoietic Stem Cell Heterogeneity
inferredcites →https://doi.org/10.1038/gt.2011.65openalex-snapshot
Lineage- and stage-restricted lentiviral vectors for the gene therapy of chronic granulomatous disease
inferredcites →https://doi.org/10.1038/nature12495openalex-snapshot
Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy
inferredcites →https://doi.org/10.1038/nature13383openalex-snapshot
Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms
inferredcites →https://doi.org/10.1038/nature13824openalex-snapshot
Clonal dynamics of native haematopoiesis
inferredcites →https://doi.org/10.1038/nature25022openalex-snapshot
From haematopoietic stem cells to complex differentiation landscapes
inferredcites →https://doi.org/10.1038/ng.2413openalex-snapshot
Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis
inferredcites →https://doi.org/10.1038/nm.3733openalex-snapshot
Age-related mutations associated with clonal hematopoietic expansion and malignancies
inferredcites →https://doi.org/10.1038/s41375-018-0047-7openalex-snapshot
Hematopoietic lineage distribution and evolutionary dynamics of clonal hematopoiesis
inferredcites →https://doi.org/10.1038/s41577-018-0065-8openalex-snapshot
Cardioimmunology: the immune system in cardiac homeostasis and disease
inferredcites →https://doi.org/10.1038/s41586-018-0317-6openalex-snapshot
Prediction of acute myeloid leukaemia risk in healthy individuals
inferredcites →https://doi.org/10.1038/s41586-018-0321-xopenalex-snapshot
Insights into clonal haematopoiesis from 8,342 mosaic chromosomal alterations
inferredcites →https://doi.org/10.1038/s41591-018-0064-0openalex-snapshot
Myeloid cell contributions to cardiovascular health and disease
inferredcites →https://doi.org/10.1038/sj.leu.2404292openalex-snapshot
The JAK2V617F mutation is detectable at very low level in peripheral blood of healthy donors
inferredcites →https://doi.org/10.1053/j.seminhematol.2016.10.002openalex-snapshot
Clonal hematopoiesis
inferredcites →https://doi.org/10.1056/nejmoa1408617openalex-snapshot
Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes
inferredcites →https://doi.org/10.1056/nejmoa1409405openalex-snapshot
Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence
inferredcites →https://doi.org/10.1056/nejmoa1701719openalex-snapshot
Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease
inferredcites →https://doi.org/10.1073/pnas.0509714102openalex-snapshot
Expression of a homodimeric type I cytokine receptor is required for JAK2V617F-mediated transformation
inferredcites →https://doi.org/10.1073/pnas.1720065115openalex-snapshot
Distinct roles of resident and nonresident macrophages in nonischemic cardiomyopathy
inferredcites →https://doi.org/10.1084/jem.20131371openalex-snapshot
Myeloproliferative neoplasms can be initiated from a single hematopoietic stem cell expressing JAK2 -V617F
inferredcites →https://doi.org/10.1084/jem.20160530openalex-snapshot
Peptidylarginine deiminase 4 promotes age-related organ fibrosis
inferredcites →https://doi.org/10.1089/hum.2006.17.949openalex-snapshot
Development of a Synthetic Promoter for Macrophage Gene Therapy
inferredcites →https://doi.org/10.1093/eurheartj/ehw024openalex-snapshot
Residual inflammatory risk: addressing the obverse side of the atherosclerosis prevention coin
inferredcites →https://doi.org/10.1093/eurheartj/ehy085openalex-snapshot
CXCL1–CXCR2 axis mediates angiotensin II-induced cardiac hypertrophy and remodelling through regulation of monocyte infiltration
inferredcites →https://doi.org/10.1111/bjh.12099openalex-snapshot
Diagnostic value of JAK 2 V 617 F somatic mutation for myeloproliferative cancer in 49 488 individuals from the general population
inferredcites →https://doi.org/10.1126/science.aag1381openalex-snapshot
Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice
inferredcites →https://doi.org/10.1126/scitranslmed.aan8292openalex-snapshot
Increased neutrophil extracellular trap formation promotes thrombosis in myeloproliferative neoplasms
inferredcites →https://doi.org/10.1161/circresaha.117.312115openalex-snapshot
Somatic Mutations and Clonal Hematopoiesis
inferredcites →https://doi.org/10.1161/circresaha.118.313225openalex-snapshot
CRISPR-Mediated Gene Editing to Assess the Roles of Tet2 and Dnmt3a in Clonal Hematopoiesis and Cardiovascular Disease
inferredcites →https://doi.org/10.1161/circresaha.118.313283openalex-snapshot
Macrophage Inflammation, Erythrophagocytosis, and Accelerated Atherosclerosis in Jak2 V617F Mice
inferredcites →https://doi.org/10.1161/circulationaha.118.038820openalex-snapshot
Wnt5a-Mediated Neutrophil Recruitment Has an Obligatory Role in Pressure Overload–Induced Cardiac Dysfunction
inferredcites →https://doi.org/10.1177/1947601910397187openalex-snapshot
JAK/STAT Pathways in Cytokine Signaling and Myeloproliferative Disorders: Approaches for Targeted Therapies
inferredcites →https://doi.org/10.1182/blood-2006-03-009472openalex-snapshot
JAK2V617F: prevalence in a large Chinese hospital population
inferredcites →https://doi.org/10.1182/blood-2006-08-042515openalex-snapshot
Leukocytosis as a major thrombotic risk factor in patients with polycythemia vera
inferredcites →https://doi.org/10.1182/blood-2006-09-046342openalex-snapshot
Leukocytosis is a risk factor for thrombosis in essential thrombocythemia: interaction with treatment, standard risk factors, and Jak2 mutation status
inferredcites →https://doi.org/10.1182/blood-2007-05-091579openalex-snapshot
Transgenic expression of JAK2V617F causes myeloproliferative disorders in mice
inferredcites →https://doi.org/10.1182/blood-2009-04-215848openalex-snapshot
Conditional expression of heterozygous or homozygous Jak2V617F from its endogenous promoter induces a polycythemia vera–like disease
inferredcites →https://doi.org/10.1182/blood-2011-04-348144openalex-snapshot
TNFα facilitates clonal expansion of JAK2V617F positive cells in myeloproliferative neoplasms
inferredcites →https://doi.org/10.1182/blood-2012-04-424911openalex-snapshot
Correlation of blood counts with vascular complications in essential thrombocythemia: analysis of the prospective PT1 cohort
inferredcites →https://doi.org/10.1182/blood-2012-09-457929openalex-snapshot
CD41 expression marks myeloid-biased adult hematopoietic stem cells and increases with age
inferredcites →https://doi.org/10.1182/blood-2013-03-460154openalex-snapshot
Myeloproliferative neoplasms and thrombosis
inferredcites →https://doi.org/10.1182/blood-2013-07-514992openalex-snapshot
VWF-mediated leukocyte recruitment with chromatin decondensation by PAD4 increases myocardial ischemia/reperfusion injury in mice
inferredcites →https://doi.org/10.1182/blood-2013-12-546218openalex-snapshot
Rapamycin relieves lentiviral vector transduction resistance in human and mouse hematopoietic stem cells
inferredcites →https://doi.org/10.1182/blood-2014-04-567024openalex-snapshot
Distinct effects of concomitant Jak2V617F expression and Tet2 loss in mice promote disease progression in myeloproliferative neoplasms
inferredcites →https://doi.org/10.1182/blood-2014-12-570200openalex-snapshot
Hematopoietic stem cells: concepts, definitions, and the new reality
inferredcites →https://doi.org/10.1182/blood-2015-06-652941openalex-snapshot
Germ line variants predispose to both JAK2 V617F clonal hematopoiesis and myeloproliferative neoplasms
inferredcites →https://doi.org/10.1182/blood-2015-11-679431openalex-snapshot
Loss of Ezh2 cooperates with Jak2V617F in the development of myelofibrosis in a mouse model of myeloproliferative neoplasm
inferredcites →https://doi.org/10.1182/blood-2016-10-696005openalex-snapshot
Myeloproliferative neoplasm stem cells
inferredcites →https://doi.org/10.1182/blood-2017-02-769869openalex-snapshot
Clonal hematopoiesis, with and without candidate driver mutations, is common in the elderly
inferredcites →https://doi.org/10.1182/blood-2018-01-829937openalex-snapshot
Lineage restriction analyses in CHIP indicate myeloid bias for TET2 and multipotent stem cell origin for DNMT3A
inferredcites →https://doi.org/10.1182/blood.v88.1.59.59openalex-snapshot
Nonrandom X-inactivation patterns in normal females: lyonization ratios vary with age
inferredcites →https://doi.org/10.1182/bloodadvances.2017007047openalex-snapshot
JAK2 V617F hematopoietic clones are present several years prior to MPN diagnosis and follow different expansion kinetics
inferredcites →https://doi.org/10.1186/1756-8722-7-25openalex-snapshot
Cardiac hypertrophy associated with myeloproliferative neoplasms in JAK2V617F transgenic mice
inferredcites →https://doi.org/10.1200/jco.2016.71.6712openalex-snapshot
Clonal Hematopoiesis Associated With Adverse Outcomes After Autologous Stem-Cell Transplantation for Lymphoma
inferredcites →https://doi.org/10.1253/circj.cj-18-0871openalex-snapshot
Clonal Hematopoiesis and Its Impact on Cardiovascular Disease
inferredcites →https://doi.org/10.3324/haematol.2010.033191openalex-snapshot
The JAK2 V617F somatic mutation, mortality and cancer risk in the general population
inferredcites →https://doi.org/10.3324/haematol.2017.172775openalex-snapshot
Expansion of EPOR-negative macrophages besides erythroblasts by elevated EPOR signaling in erythrocytosis mouse models
inferredcites →https://doi.org/10.3791/59977openalex-snapshot
Lentiviral CRISPR/Cas9-Mediated Genome Editing for the Study of Hematopoietic Cells in Disease Models
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Agent Orange Exposure Enhances the Increased Risk of Cardiovascular Disease in Veterans with Myeloproliferative Neoplasms
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Clonal Hematopoiesis and Incident Heart Failure
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Association of clonal hematopoiesis mutations with clinical outcomes: A systematic review and meta‐analysis
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New advances in the role of JAK2 V617F mutation in myeloproliferative neoplasms
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Clonal Haematopoiesis of Indeterminate Potential: Associations with Heart Failure Incidence, Clinical Parameters and Biomarkers
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Clonal Haematopoiesis is Associated with Major Adverse Cardiovascular Events in Patients with Hypertrophic Cardiomyopathy
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Exploring the Associations Between Clonal Hematopoiesis of Indeterminate Potential, Myeloid Malignancy, and Atherosclerosis
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The Origin of Clonal Hematopoiesis and Its Implication in Human Diseases
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Einfluss der klonalen Hämatopoese auf nicht-hämatologische Erkrankungen und Alterungsprozesse
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A feedback loop: Interactions between Inflammatory Signals and Clonal Hematopoiesis in Cardiovascular Disease
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A new risk factor associated with cardiovascular disease: clonal hematopoiesis of indeterminate potential
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In-Hospital and readmission outcomes of patients with myeloproliferative neoplasms and atrial fibrillation: insights from the National Readmissions Database
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Clonal hematopoiesis of indeterminate potential (CHIP) in cerebromicrovascular aging: implications for vascular contributions to cognitive impairment and dementia (VCID)
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Myeloproliferative Neoplasms and Cardiovascular Disease: A Review
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Clonal Hematopoiesis: Connecting Aging and Inflammation in Atherosclerosis
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Evidence of Clonal Hematopoiesis and Risk of Heart Failure
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Novel Pathophysiological Mechanisms of Thrombosis in Myeloproliferative Neoplasms
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Pulmonary hypertension is associated with poor cardiovascular and hematologic outcomes in patients with myeloproliferative neoplasms and cardiovascular disease
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Novel Murine Models of Hematopoietic–Endothelial Crosstalk in JAK2V617F-Associated Cardiovascular Disease
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Oridonin as a novel KDM5C inhibitor alleviates clonal hematopoiesis-induced cardiac aging via H3K4me3-dependent SASP suppression
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Readmission outcomes after acute coronary syndrome among patients with myeloproliferative neoplasms
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Early detection and intervention of clonal hematopoiesis for preventing hematological malignancies
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Clonal hematopoiesis driven by mutated DNMT3A promotes inflammatory bone loss
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Clonal hematopoiesis of indeterminate potential (CHIP): A potential contributor to lymphoma
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Clonal Hematopoiesis of Indeterminate Potential and Diabetic Kidney Disease: A Nested Case-Control Study
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Therapy-Related Clonal Hematopoiesis
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Is There a Causal Link Between Periodontitis and Cardiovascular Disease? A Concise Review of Recent Findings
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In-Hospital and readmission outcomes of patients with myeloproliferative neoplasms and heart failure: Insights from the National Readmissions Database
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Clonal Hematopoiesis: A New Step Linking Inflammation to Heart Failure
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A New Murine Model of Clonal Hematopoiesis Investigates JAK2V617F in Heart Failure
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Association of Clonal Hematopoiesis With Incident Heart Failure
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Common Pathophysiology in Cancer, Atrial Fibrillation, Atherosclerosis, and Thrombosis: JACC: CardioOncology State-of-the-Art Review
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Cardiovascular Disease in Myeloproliferative Neoplasms
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Beyond Thrombosis: Pulmonary Hypertension and Heart Failure in Patients With Myeloproliferative Neoplasms
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Clonal Hematopoiesis in Cancer and Cardiovascular Disease
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Cardiovascular Considerations of JAK Inhibitors in Patients With Hematologic Malignancies
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Clonal hematopoiesis and cardiovascular diseases: role of JAK2V617F
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JAK-STAT inhibition reduces endothelial prothrombotic activation and leukocyte–endothelial proadhesive interactions
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Oral squamous cell carcinoma with essential thrombocythemia and positive JAK2 (V617F) mutation
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Anthracycline induced left ventricular dysfunction in AML: A focus on the molecularly defined future of cardio-oncology
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Clonality in haematopoietic stem cell ageing
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Advances in understanding the molecular basis of clonal hematopoiesis
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Clonal haematopoiesis of emerging significance
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Assessment of medullary and extramedullary myelopoiesis in cardiovascular diseases
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The AIM2 inflammasome: A novel biomarker and target in cardiovascular disease
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Clonal hematopoiesis, cardiovascular disease and cancer treatment-induced cardiotoxicity
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Clonal hematopoiesis: Mutation-specific adaptation to environmental change
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Putative Mechanisms Underlying Cardiovascular Disease Associated with Clonal Hematopoiesis of Indeterminate Potential
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Clonal hematopoiesis and inflammation – the perpetual cycle
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Importance of clonal hematopoiesis in heart failure
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Clonal hematopoiesis and cardiovascular disease in cancer patients and survivors
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Clonal hematopoiesis of indeterminate potential and cardiovascular disease
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Clonal hematopoiesis of indeterminate potential (CHIP): Linking somatic mutations, hematopoiesis, chronic inflammation and cardiovascular disease
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Infection risk associated with clonal hematopoiesis of indeterminate potential is partly mediated by hematologic cancer transformation in the UK Biobank
inferred← citeshttps://doi.org/10.1038/s41375-024-02464-8openalex-snapshot
A CADASIL NOTCH3 mutation leads to clonal hematopoiesis and expansion of Dnmt3a-R878H hematopoietic clones
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JAK2V617F mutation drives vascular resident macrophages toward a pathogenic phenotype and promotes dissecting aortic aneurysm
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A cardioimmunologist’s toolkit: genetic tools to dissect immune cells in cardiac disease
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Clonal haematopoiesis in cardiovascular disease: prognostic role and novel therapeutic target
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Immunometabolism in heart failure
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Germline risk of clonal haematopoiesis
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Inflammageing and clonal haematopoiesis interplay and their impact on human disease
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Targeting innate immunity-driven inflammation in CKD and cardiovascular disease
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Clonal haematopoiesis, ageing and kidney disease
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Clonal hematopoiesis of indeterminate potential is associated with acute kidney injury
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Prospective characterization of clonal hematopoiesis and its clinical associations in elderly patients
inferred← citeshttps://doi.org/10.1038/s44161-021-00015-3openalex-snapshot
Clonal hematopoiesis in cardiovascular disease and therapeutic implications
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Clonal haematopoiesis of indeterminate potential: intersections between inflammation, vascular disease and heart failure
inferred← citeshttps://doi.org/10.1051/medsci/2023069openalex-snapshot
Une mutation « gain de fonction » de JAK2 favorise la formation d’anévrismes aortiques disséquants en induisant un phénotype pro-inflammatoire des macrophages vasculaires résidents
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Clonal Hematopoiesis of Indeterminate Potential and Kidney Function Decline in the General Population
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Cardiovascular complications in patients with myeloproliferative neoplasms: What hematologists need to know
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Ruxolitinib and heart failure outcomes among patients with myelofibrosis
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Promoting effect of long non-coding RNA SNHG1 on osteogenic differentiation of fibroblastic cells from the posterior longitudinal ligament by the microRNA-320b/IFNGR1 network
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Murine models of clonal haematopoiesis to assess mechanisms of cardiovascular disease
inferred← citeshttps://doi.org/10.1093/cvr/cvac132openalex-snapshot
Mechanisms shared between cancer, heart failure, and targeted anti-cancer therapies
inferred← citeshttps://doi.org/10.1093/eurheartj/ehaa848openalex-snapshot
Clonal haematopoiesis and cardiovascular disease: how low can you go?
inferred← citeshttps://doi.org/10.1093/eurheartj/ehab197openalex-snapshot
Leveraging clinical epigenetics in heart failure with preserved ejection fraction: a call for individualized therapies
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CXCL1–CXCR2 axis mediates angiotensin II-induced cardiac hypertrophy and remodelling through regulation of monocyte infiltration
inferred← citeshttps://doi.org/10.1093/jjco/hyac210openalex-snapshot
Clonal heamatopoiesis and associated cardiovascular diseases
inferred← citeshttps://doi.org/10.1097/coh.0000000000000953openalex-snapshot
Understanding residual risk of cardiovascular disease in people with HIV
inferred← citeshttps://doi.org/10.1097/hco.0000000000000726openalex-snapshot
Genetics of age-related clonal hematopoiesis and atherosclerotic cardiovascular disease
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Persistent inflammatory residual risk despite aggressive cholesterol-lowering therapy: what is next?
inferred← citeshttps://doi.org/10.1097/hco.0000000000000961openalex-snapshot
Epigenetic remodeling in heart failure with preserved ejection fraction
inferred← citeshttps://doi.org/10.1097/hco.0000000000001032openalex-snapshot
Clonal hematopoiesis: the nonhereditary genetics of age-associated cardiovascular disease
inferred← citeshttps://doi.org/10.1097/mol.0000000000000661openalex-snapshot
Editorial: Clonal hematopoiesis: a link between inflammation, ageing and cardiovascular disease
inferred← citeshttps://doi.org/10.1101/2020.03.22.002774openalex-snapshot
Hematopoietic p53 loss cell-extrinsically defines an immune infiltrated microenvironment in leukemia and pre-leukemia
inferred← citeshttps://doi.org/10.1101/2023.02.22.529500openalex-snapshot
Identification of novel prognostic targets in coronary artery disease and related complications using bioinformatics and next generation sequencing data analysis
inferred← citeshttps://doi.org/10.1101/2023.07.12.548716openalex-snapshot
Unlocking the Role of Endothelial MPL Receptor and JAK2V617F Mutation: Insights into Cardiovascular Dysfunction in MPNs and CHIP
inferred← citeshttps://doi.org/10.1111/ajt.17172openalex-snapshot
Clonal hematopoiesis confers an increased mortality risk in orthotopic heart transplant recipients
inferred← citeshttps://doi.org/10.1111/bph.16355openalex-snapshot
The cytoplasmic sensor, the AIM2 inflammasome: A precise therapeutic target in vascular and metabolic diseases
inferred← citeshttps://doi.org/10.1111/imr.13382openalex-snapshot
DNA sensors in metabolic and cardiovascular diseases: Molecular mechanisms and therapeutic prospects
inferred← citeshttps://doi.org/10.1111/imr.70094openalex-snapshot
The Immunological Consequences of Clonal Hematopoiesis in Heart Failure
inferred← citeshttps://doi.org/10.1111/joim.13130openalex-snapshot
The role of clonal haematopoiesis in cardiovascular diseases: epidemiology and experimental studies
inferred← citeshttps://doi.org/10.1111/jth.15095openalex-snapshot
Endothelial JAK2V617F mutation leads to thrombosis, vasculopathy, and cardiomyopathy in a murine model of myeloproliferative neoplasm
inferred← citeshttps://doi.org/10.1136/ard-2023-224933openalex-snapshot
Clonal haematopoiesis across the age spectrum of vasculitis patients with Takayasu’s arteritis, ANCA-associated vasculitis and giant cell arteritis
inferred← citeshttps://doi.org/10.1146/annurev-genom-120722-100409openalex-snapshot
Clinical and Therapeutic Implications of Clonal Hematopoiesis
inferred← citeshttps://doi.org/10.1146/annurev-pathmechdis-012419-032544openalex-snapshot
Cardiovascular Disease, Aging, and Clonal Hematopoiesis
inferred← citeshttps://doi.org/10.1146/annurev-physiol-061121-040048openalex-snapshot
Somatic Mosaicism in Biology and Disease
inferred← citeshttps://doi.org/10.1152/ajpheart.00577.2025openalex-snapshot
Clonal hematopoiesis of indeterminate potential: a unifying mechanism linking metainflammation and cardiometabolic diseases
inferred← citeshttps://doi.org/10.1152/physiol.00004.2023openalex-snapshot
Inflammatory Mechanisms in Heart Failure with Preserved Ejection Fraction
inferred← citeshttps://doi.org/10.1152/physrev.00004.2022openalex-snapshot
Clonal hematopoiesis, somatic mosaicism, and age-associated disease
inferred← citeshttps://doi.org/10.1155/2021/6687096openalex-snapshot
NETosis as a Pathogenic Factor for Heart Failure
inferred← citeshttps://doi.org/10.1161/atvbaha.122.318181openalex-snapshot
Genomic Aging, Clonal Hematopoiesis, and Cardiovascular Disease
inferred← citeshttps://doi.org/10.1161/atvbaha.124.321008openalex-snapshot
Decoding Endothelial MPL and JAK2V617F Mutation: Insight Into Cardiovascular Dysfunction in Myeloproliferative Neoplasms
inferred← citeshttps://doi.org/10.1161/atvbaha.126.325061openalex-snapshot
Targeting Thrombopoietin/MPL Signaling to Mitigate JAK2V617F-Driven Cardiac Microvascular Disease
inferred← citeshttps://doi.org/10.1161/cir.0000000000001404openalex-snapshot
Clonal Hematopoiesis and Its Cardiovascular Implications: A Scientific Statement From the American Heart Association
inferred← citeshttps://doi.org/10.1161/circheartfailure.125.013941openalex-snapshot
Reframing the Cytokine Hypothesis: Lessons Learned From Clonal Hematopoiesis
inferred← citeshttps://doi.org/10.1161/circresaha.120.318575openalex-snapshot
A Single-Cell Analysis of DNMT3A-Mediated Clonal Hematopoiesis in Heart Failure
inferred← citeshttps://doi.org/10.1161/circresaha.121.319314openalex-snapshot
The Cancer Therapy-Related Clonal Hematopoiesis Driver Gene Ppm1d Promotes Inflammation and Non-Ischemic Heart Failure in Mice
inferred← citeshttps://doi.org/10.1161/circresaha.121.319809openalex-snapshot
Somatic Mutations in Cardiovascular Disease
inferred← citeshttps://doi.org/10.1161/circresaha.125.325489openalex-snapshot
Contributions of Noncardiac Organ–Heart Immune Crosstalk and Somatic Mosaicism to Heart Failure: Current Knowledge and Perspectives
inferred← citeshttps://doi.org/10.1161/circulationaha.123.064170openalex-snapshot
Clonal Hematopoiesis in Clinical and Experimental Heart Failure With Preserved Ejection Fraction
inferred← citeshttps://doi.org/10.1161/jaha.123.030603openalex-snapshot
Clonal Hematopoiesis of Indeterminate Potential From a Heart Failure Specialist's Point of View
inferred← citeshttps://doi.org/10.1161/jaha.124.035498openalex-snapshot
Clonal Hematopoiesis in Chronic Thromboembolic Pulmonary Hypertension
inferred← citeshttps://doi.org/10.1165/rcmb.2020-0384edopenalex-snapshot
Inhibiting Jak2 Ameliorates Pulmonary Hypertension: Fulfilling the Promise of Precision Medicine
inferred← citeshttps://doi.org/10.1172/jci.insight.135204openalex-snapshot
Tet2-mediated clonal hematopoiesis in nonconditioned mice accelerates age-associated cardiac dysfunction
inferred← citeshttps://doi.org/10.1172/jci.insight.146076openalex-snapshot
TP53-mediated therapy-related clonal hematopoiesis contributes to doxorubicin-induced cardiomyopathy by augmenting a neutrophil-mediated cytotoxic response
inferred← citeshttps://doi.org/10.1172/jci155724openalex-snapshot
Erythroid lineage Jak2V617F expression promotes atherosclerosis through erythrophagocytosis and macrophage ferroptosis
inferred← citeshttps://doi.org/10.1177/1358863x261437058openalex-snapshot
Clonal hematopoiesis of indeterminate potential (CHIP), vascular somatic mutation, and cardiovascular disease: A narrative review
inferred← citeshttps://doi.org/10.1182/blood.2019000989openalex-snapshot
Clonal hematopoiesis and non-hematologic disorders
inferred← citeshttps://doi.org/10.1182/blood.2022018825openalex-snapshot
A practical approach to curate clonal hematopoiesis of indeterminate potential in human genetic datasets
inferred← citeshttps://doi.org/10.1182/blood.2023022222openalex-snapshot
Causes and consequences of clonal hematopoiesis
inferred← citeshttps://doi.org/10.1182/blood.2023022260openalex-snapshot
Jak2 V617F clonal hematopoiesis promotes arterial thrombosis via platelet activation and cross talk
inferred← citeshttps://doi.org/10.1182/bloodadvances.2023011692openalex-snapshot
Exacerbation of thromboinflammation by JAK2 V617F mutation worsens the prognosis of cerebral venous sinus thrombosis
inferred← citeshttps://doi.org/10.1186/s12872-024-03729-xopenalex-snapshot
Coenzyme Q10 mitigates macrophage mediated inflammation in heart following myocardial infarction via the NLRP3/IL1β pathway
inferred← citeshttps://doi.org/10.1253/circj.cj-21-0258openalex-snapshot
NLRP3 Inflammasome as a Common Denominator of Atherosclerosis and Abdominal Aortic Aneurysm
inferred← citeshttps://doi.org/10.1253/circj.cj-23-0838openalex-snapshot
Shared and Reciprocal Mechanisms Between Heart Failure and Cancer ― An Emerging Concept of Heart-Cancer Axis ―
inferred← citeshttps://doi.org/10.1515/labmed-2022-0050openalex-snapshot
Clonal hematopoiesis of indeterminate potential: clinical relevance of an incidental finding in liquid profiling
inferred← citeshttps://doi.org/10.1556/650.2024.33055openalex-snapshot
A JAK2 szomatikus génmutáció lehetséges betegségmódosító hatása a cardiovascularis kórképek kialakulásában
inferred← citeshttps://doi.org/10.15829/1560-4071-2024-6016openalex-snapshot
Clonal hematopoiesis of indeterminate potential and heart failure
inferred← citeshttps://doi.org/10.1681/asn.0000000671openalex-snapshot
Association of Clonal Hematopoiesis of Indeterminate Potential with Cardiovascular Events in Patients with CKD
inferred← citeshttps://doi.org/10.1681/asn.2021060774openalex-snapshot
Association of Clonal Hematopoiesis of Indeterminate Potential with Worse Kidney Function and Anemia in Two Cohorts of Patients with Advanced Chronic Kidney Disease
inferred← citeshttps://doi.org/10.20517/jca.2021.06openalex-snapshot
Hematopoietic JAK2V617F-mediated clonal hematopoiesis: AIM2 understand mechanisms of atherogenesis
inferred← citeshttps://doi.org/10.20517/jca.2024.15openalex-snapshot
Geroscience in heart failure: the search for therapeutic targets in the shared pathobiology of human aging and heart failure
inferred← citeshttps://doi.org/10.2459/jcm.0000000000001520openalex-snapshot
Clonal hematopoiesis of indeterminate potential: implications for the cardiologists
inferred← citeshttps://doi.org/10.26599/oshm.2025.9610016openalex-snapshot
Clonal hematopoiesis: linking hematopoietic stem cell aging with age-related diseases
inferred← citeshttps://doi.org/10.30629/0023-2149-2023-101-7-8-353-360openalex-snapshot
Epigenetic signals in heart failure: new opportunities for early diagnosis and eff ective therapy
inferred← citeshttps://doi.org/10.3389/fimmu.2020.589048openalex-snapshot
JAK2V617F Mutation Promoted IL-6 Production and Glycolysis via Mediating PKM1 Stabilization in Macrophages
inferred← citeshttps://doi.org/10.3389/fimmu.2023.1161832openalex-snapshot
High cell-free DNA is associated with disease progression, inflammasome activation and elevated levels of inflammasome-related cytokine IL-18 in patients with myelofibrosis
inferred← citeshttps://doi.org/10.3389/fncel.2024.1487867openalex-snapshot
Tet2-mediated clonal hematopoiesis modestly improves neurological deficits and is associated with inflammation resolution in the subacute phase of experimental stroke
inferred← citeshttps://doi.org/10.3389/fonc.2023.1303785openalex-snapshot
Molecular and clinical aspects relevant for counseling individuals with clonal hematopoiesis of indeterminate potential
inferred← citeshttps://doi.org/10.3389/fragi.2022.841796openalex-snapshot
Clonal Hematopoiesis Analyses in Clinical, Epidemiologic, and Genetic Aging Studies to Unravel Underlying Mechanisms of Age-Related Dysfunction in Humans
inferred← citeshttps://doi.org/10.3389/frhem.2024.1459154openalex-snapshot
The CHIP-clinic as the catalyst of preventive medicine
inferred← citeshttps://doi.org/10.3390/antiox12111944openalex-snapshot
Inflammation in Myocardial Ischemia/Reperfusion Injury: Underlying Mechanisms and Therapeutic Potential
inferred← citeshttps://doi.org/10.3390/biomedicines10040782openalex-snapshot
Somatic Mutations of Hematopoietic Cells Are an Additional Mechanism of Body Aging, Conducive to Comorbidity and Increasing Chronification of Inflammation
inferred← citeshttps://doi.org/10.3390/cancers13081968openalex-snapshot
Myelodysplasia Syndrome, Clonal Hematopoiesis and Cardiovascular Disease
inferred← citeshttps://doi.org/10.3390/cancers18172775openalex-snapshot
The Current Landscape of Pulmonary Hypertension in Myeloproliferative Neoplasms
inferred← citeshttps://doi.org/10.3390/cells10123266openalex-snapshot
Personalized Cell Therapy for Patients with Peripheral Arterial Diseases in the Context of Genetic Alterations: Artificial Intelligence-Based Responder and Non-Responder Prediction
inferred← citeshttps://doi.org/10.3390/cells12020294openalex-snapshot
Dexamethasone and OLT1177 Cooperate in the Reduction of Melanoma Growth by Inhibiting STAT3 Functions
inferred← citeshttps://doi.org/10.3390/cells9092136openalex-snapshot
Cytokine Profiling in Myeloproliferative Neoplasms: Overview on Phenotype Correlation, Outcome Prediction, and Role of Genetic Variants
inferred← citeshttps://doi.org/10.3390/diagnostics12071613openalex-snapshot
Clinical Significance of Clonal Hematopoiesis of Indeterminate Potential in Hematology and Cardiovascular Disease
inferred← citeshttps://doi.org/10.3390/hematolrep15020040openalex-snapshot
Risk Factors for Death or Cardiovascular Events after Acute Coronary Syndrome in Patients with Myeloproliferative Neoplasms
inferred← citeshttps://doi.org/10.3390/ijms22189867openalex-snapshot
Telomere Attrition and Clonal Hematopoiesis of Indeterminate Potential in Cardiovascular Disease
inferred← citeshttps://doi.org/10.3390/ijms26052052openalex-snapshot
Revolutionising Cardio-Oncology Care with Precision Genomics
inferred← citeshttps://doi.org/10.3390/ijms27135663openalex-snapshot
Impact of CaV1.3 L-Type Calcium Channels on Arrhythmogenesis in Cancer
inferred← citeshttps://doi.org/10.3390/ijtm6020013openalex-snapshot
Clinical and Molecular Challenges in Diagnosing Myeloproliferative Neoplasms with Low JAK2V617F Allelic Burden: A Single-Center Perspective and Literature Overview
inferred← citeshttps://doi.org/10.3390/jcm9082480openalex-snapshot
Translating Evidence from Clonal Hematopoiesis to Cardiovascular Disease: A Systematic Review
inferred← citeshttps://doi.org/10.3390/life12081135openalex-snapshot
Molecular Pathways in Clonal Hematopoiesis: From the Acquisition of Somatic Mutations to Transformation into Hematologic Neoplasm
inferred← citeshttps://doi.org/10.3390/neurolint17020019openalex-snapshot
The Role of Somatic Mutations in Ischemic Stroke: CHIP’s Impact on Vascular Health
inferred← citeshttps://doi.org/10.37155/2972-4759-2023-01-01-4openalex-snapshot
Protocol for a pilot trial to implement diagnostics for clonal hematopoiesis of indeterminate potential into routine clinical care of older patients with breast cancer
inferred← citeshttps://doi.org/10.3791/61875openalex-snapshot
Bone Marrow Transplantation Procedures in Mice to Study Clonal Hematopoiesis
inferred← citeshttps://doi.org/10.4330/wjc.v16.i11.651openalex-snapshot
Cardiac hypertrophy in polycythemia vera: A case report and review of literature
inferred← citeshttps://doi.org/10.5167/uzh-229357openalex-snapshot
Epigenetic remodeling in heart failure with preserved ejection fraction
inferred← citeshttps://doi.org/10.6084/m9.figshare.25101100openalex-snapshot
Additional file 1 of Coenzyme Q10 mitigates macrophage mediated inflammation in heart following myocardial infarction via the NLRP3/IL1β pathway
inferred← citeshttps://doi.org/10.64898/2026.04.01.715884openalex-snapshot
Targeting TPO/MPL Signaling to Mitigate JAK2V617F-driven Cardiac Microvascular Disease
inferred← citeshttps://doi.org/10.70675/6d79033ez0b64z40a5z885cza985c4f78f60openalex-snapshot
Aménagement des éco–quartiers et de la biodiversité
inferred← citeshttps://doi.org/10.70675/d0594ae8z342ez443az8ec7z19db6dbc94e6openalex-snapshot
Thrombose veineuse cérébrale et néoplasies myéloprolifératives : impact physiopathologique de la mutation JAK2V617F
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