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Controlled drug delivery with nanoassemblies of redox-responsive prodrug and polyprodrug amphiphiles
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DNA Nanostructures at the Interface with Biology
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Well-defined polymer-drug conjugate engineered with redox and pH-sensitive release mechanism for efficient delivery of paclitaxel
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One-component nanomedicine
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αvβ3 Integrin-targeted reduction-sensitive micellar mertansine prodrug: Superb drug loading, enhanced stability, and effective inhibition of melanoma growth in vivo
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Synergistic antitumor activity of a self-assembling camptothecin and capecitabine hybrid prodrug for improved efficacy
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Doxorubicin delivered by a redox-responsive dasatinib-containing polymeric prodrug carrier for combination therapy
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Self-assembling mertansine prodrug improves tolerability and efficacy of chemotherapy against metastatic triple-negative breast cancer
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Modulating intracellular oxidative stress via engineered nanotherapeutics
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Self-assembling and self-formulating prodrug hydrogelator extends survival in a glioblastoma resection and recurrence model
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Self-assembly of oxidation-responsive polyethylene glycol-paclitaxel prodrug for cancer chemotherapy
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Building nanostructures with drugs
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Block copolymer micelles for drug delivery: design, characterization and biological significance
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Supramolecular Assembly of Peptide Amphiphiles
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Aptamer–Drug Conjugates
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Facile Fabrication of 10-Hydroxycamptothecin-Backboned Amphiphilic Polyprodrug with Precisely Tailored Drug Loading Content for Controlled Release
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Amphiphilic Drug Conjugates as Nanomedicines for Combined Cancer Therapy
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Polymeric Engineering of Aptamer–Drug Conjugates for Targeted Cancer Therapy
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Fabrication of Reductive-Responsive Prodrug Nanoparticles with Superior Structural Stability by Polymerization-Induced Self-Assembly and Functional Nanoscopic Platform for Drug Delivery
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Glutathione-Sensitive Hyaluronic Acid-SS-Mertansine Prodrug with a High Drug Content: Facile Synthesis and Targeted Breast Tumor Therapy
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Near-Infrared Light-Activated Photochemical Internalization of Reduction-Responsive Polyprodrug Vesicles for Synergistic Photodynamic Therapy and Chemotherapy
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Cascade-Promoted Photo-Chemotherapy against Resistant Cancers by Enzyme-Responsive Polyprodrug Nanoplatforms
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Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials
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Efficient Click Synthesis of a Protonized and Reduction-Sensitive Amphiphilic Small-Molecule Prodrug Containing Camptothecin and Gemcitabine for a Drug Self-Delivery System
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Angiopep2-Conjugated Star-Shaped Polyprodrug Amphiphiles for Simultaneous Glioma-Targeting Therapy and MR Imaging
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ROS-Responsive Nanoparticles Formed from RGD–Epothilone B Conjugate for Targeted Cancer Therapy
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Responsive Prodrug Self-Assembled Vesicles for Targeted Chemotherapy in Combination with Intracellular Imaging
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“Bottom-Up” Construction of Hyperbranched Poly(prodrug-co-photosensitizer) Amphiphiles Unimolecular Micelles for Chemo-Photodynamic Dual Therapy
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Hyaluronic Acid-Shelled Disulfide-Cross-Linked Nanopolymersomes for Ultrahigh-Efficiency Reactive Encapsulation and CD44-Targeted Delivery of Mertansine Toxin
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Mitochondria-Specific Anticancer Drug Delivery Based on Reduction-Activated Polyprodrug for Enhancing the Therapeutic Effect of Breast Cancer Chemotherapy
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Smart Unimolecular Micelle-Based Polyprodrug with Dual-Redox Stimuli Response for Tumor Microenvironment: Enhanced in Vivo Delivery Efficiency and Tumor Penetration
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Enzyme-Triggered Transcytosis of Dendrimer–Drug Conjugate for Deep Penetration into Pancreatic Tumors
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Supramolecular Aggregation-Induced Emission Nanodots with Programmed Tumor Microenvironment Responsiveness for Image-Guided Orthotopic Pancreatic Cancer Therapy
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Transformative Nanomedicine of an Amphiphilic Camptothecin Prodrug for Long Circulation and High Tumor Uptake in Cancer Therapy
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Fine-Tuning the Linear Release Rate of Paclitaxel-Bearing Supramolecular Filament Hydrogels through Molecular Engineering
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Amphiphilic Building Blocks for Self-Assembly: From Amphiphiles to Supra-amphiphiles
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Preparation and Biological Characterization of Polymeric Micelle Drug Carriers with Intracellular pH-Triggered Drug Release Property: Tumor Permeability, Controlled Subcellular Drug Distribution, and Enhanced in Vivo Antitumor Efficacy
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Supramolecular Nanostructures Formed by Anticancer Drug Assembly
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Polyprodrug Amphiphiles: Hierarchical Assemblies for Shape-Regulated Cellular Internalization, Trafficking, and Drug Delivery
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Combination of Small Molecule Prodrug and Nanodrug Delivery: Amphiphilic Drug–Drug Conjugate for Cancer Therapy
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Cell-Penetrating Hyperbranched Polyprodrug Amphiphiles for Synergistic Reductive Milieu-Triggered Drug Release and Enhanced Magnetic Resonance Signals
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Dimeric Drug Polymeric Nanoparticles with Exceptionally High Drug Loading and Quantitative Loading Efficiency
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Enzyme-Instructed Molecular Self-assembly Confers Nanofibers and a Supramolecular Hydrogel of Taxol Derivative
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Prodrugs Forming High Drug Loading Multifunctional Nanocapsules for Intracellular Cancer Drug Delivery
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Engineering Intracellular Delivery Nanocarriers and Nanoreactors from Oxidation-Responsive Polymersomes via Synchronized Bilayer Cross-Linking and Permeabilizing Inside Live Cells
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Blurring the Role of Oligonucleotides: Spherical Nucleic Acids as a Drug Delivery Vehicle
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High Drug Loading and Sub-Quantitative Loading Efficiency of Polymeric Micelles Driven by Donor–Receptor Coordination Interactions
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Positively Charged Polyprodrug Amphiphiles with Enhanced Drug Loading and Reactive Oxygen Species-Responsive Release Ability for Traceable Synergistic Therapy
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Supramolecular Polymer-Based Nanomedicine: High Therapeutic Performance and Negligible Long-Term Immunotoxicity
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Macrocyclization of a Class of Camptothecin Analogues into Tubular Supramolecular Polymers
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Molecular Self-Assembly of Bioorthogonal Aptamer-Prodrug Conjugate Micelles for Hydrogen Peroxide and pH-Independent Cancer Chemodynamic Therapy
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Conjugating Aptamer and Mitomycin C with Reductant-Responsive Linker Leading to Synergistically Enhanced Anticancer Effect
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Disulfide Cross-Linked Phosphorylcholine Micelles for Triggered Release of Camptothecin
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Antitumor Activity of Peptide Amphiphile Nanofiber-Encapsulated Camptothecin
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Light-Induced Cytosolic Activation of Reduction-Sensitive Camptothecin-Loaded Polymeric Micelles for Spatiotemporally Controlled in Vivo Chemotherapy
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Multiwalled Nanotubes Formed by Catanionic Mixtures of Drug Amphiphiles
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Syntheses of Poly-DL-Serine Derivatives containing Cytotoxic Groups
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Engineered modular biomaterial logic gates for environmentally triggered therapeutic delivery
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Self-assembling nanoprobes that display off/on 19F nuclear magnetic resonance signals for protein detection and imaging
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Augmenting drug–carrier compatibility improves tumour nanotherapy efficacy
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Self-assembling chimeric polypeptide–doxorubicin conjugate nanoparticles that abolish tumours after a single injection
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Nanocarriers as an emerging platform for cancer therapy
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Cancer nanomedicine: progress, challenges and opportunities
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The expanding role of prodrugs in contemporary drug design and development
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Mitochondria-specific drug release and reactive oxygen species burst induced by polyprodrug nanoreactors can enhance chemotherapy
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A programmable polymer library that enables the construction of stimuli-responsive nanocarriers containing logic gates
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Enzyme-activatable polymer–drug conjugate augments tumour penetration and treatment efficacy
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Polymer–drug conjugate therapeutics: advances, insights and prospects
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Nucleoside, nucleotide and oligonucleotide based amphiphiles: a successful marriage of nucleic acids with lipids
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Drug release from hydrazone-containing peptide amphiphiles
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Switching of self-assembly in a peptide nanostructure with a specific enzyme
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Supramolecular filaments containing a fixed 41% paclitaxel loading
inferredcites →https://doi.org/10.1039/c3cc49453eopenalex-snapshot
Linker-determined drug release mechanism of free camptothecin from self-assembling drug amphiphiles
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Supramolecular self-assemblies as functional nanomaterials
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Redox-responsive polymers for drug delivery: from molecular design to applications
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Redox-responsive self-assembled chain-shattering polymeric therapeutics
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Camptothecin prodrug block copolymer micelles with high drug loading and target specificity
inferredcites →https://doi.org/10.1039/c4tb01084aopenalex-snapshot
Synthesis and self-assembly of a mikto-arm star dual drug amphiphile containing both paclitaxel and camptothecin
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Reduction-responsive dithiomaleimide-based nanomedicine with high drug loading and FRET-indicated drug release
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Rapidly cell-penetrating and reductive milieu-responsive nanoaggregates assembled from an amphiphilic folate-camptothecin prodrug for enhanced drug delivery and controlled release
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Self-assembling nanowires of an amphiphilic camptothecin prodrug derived from homologous derivative conjugation
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A multi-stimuli responsive nanoparticulate SN38 prodrug for cancer chemotherapy
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Gemcitabine–camptothecin conjugates: a hybrid prodrug for controlled drug release and synergistic therapeutics
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Construction of drug–drug conjugate supramolecular nanocarriers based on water-soluble pillar[6]arene for combination chemotherapy
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Molecularly precise self-assembly of theranostic nanoprobes within a single-molecular framework for in vivo tracking of tumor-specific chemotherapy
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A sequence-activated AND logic dual-channel fluorescent probe for tracking programmable drug release
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Fabrication of biocleavable crosslinked polyprodrug vesicles via reversible donor–acceptor interactions for enhanced anticancer drug delivery
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Sequence-defined non-natural polymers: synthesis and applications
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The role of critical micellization concentration in efficacy and toxicity of supramolecular polymers
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Supramolecular nanoscale drug-delivery system with ordered structure
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Supramolecular prodrug hydrogelator as an immune booster for checkpoint blocker–based immunotherapy
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A Phospholipid Derivative of Cytosine Arabinoside and Its Conversion to Phosphatidylinositol by Animal Tissue
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Molecular Self-Assembly and Nanochemistry: a Chemical Strategy for the Synthesis of Nanostructures
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