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Transcriptomic correlates of organ failure extent in sepsis
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1007/bf01709751openalex-snapshot
The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure
inferredcites →https://doi.org/10.1007/s001340050931openalex-snapshot
The use of maximum SOFA score to quantify organ dysfunction/failure in intensive care. Results of a prospective, multicentre study
inferredcites →https://doi.org/10.1007/s00281-013-0364-xopenalex-snapshot
Mechanisms regulating neutrophil survival and cell death
inferredcites →https://doi.org/10.1016/s0140-6736(06)69005-3openalex-snapshot
Neutrophils in development of multiple organ failure in sepsis
inferredcites →https://doi.org/10.1016/s1473-3099(13)70001-xopenalex-snapshot
Immunosuppression in sepsis: a novel understanding of the disorder and a new therapeutic approach
inferredcites →https://doi.org/10.1038/pr.2013.11openalex-snapshot
Genome-wide expression profiling in pediatric septic shock
inferredcites →https://doi.org/10.1074/jbc.m109.042903openalex-snapshot
Structural Characterization of Mouse Neutrophil Serine Proteases and Identification of Their Substrate Specificities
inferredcites →https://doi.org/10.1084/jem.20111354openalex-snapshot
A genomic storm in critically injured humans
inferredcites →https://doi.org/10.1089/sur.2006.7.s-69openalex-snapshot
Organ Dysfunction in Patients with Severe Sepsis
inferredcites →https://doi.org/10.1093/infdis/jis651openalex-snapshot
Interleukin-1 Promotes Coagulation, Which Is Necessary for Protective Immunity in the Lung Against Streptococcus pneumoniae Infection
inferredcites →https://doi.org/10.1097/01.ccm.0000194725.48928.3aopenalex-snapshot
Sepsis in European intensive care units: Results of the SOAP study*
inferredcites →https://doi.org/10.1097/01.sla.0000251619.10648.32openalex-snapshot
Gene Expression Profiles Differentiate Between Sterile SIRS and Early Sepsis
inferredcites →https://doi.org/10.1097/moh.0b013e32834115d1openalex-snapshot
Neutrophil serine proteases: mediators of innate immune responses
inferredcites →https://doi.org/10.1097/shk.0b013e31829ee604openalex-snapshot
Identifying Key Regulatory Genes in the Whole Blood of Septic Patients to Monitor Underlying Immune Dysfunctions
inferredcites →https://doi.org/10.1128/iai.01213-09openalex-snapshot
Characterization and Modulation of the Immunosuppressive Phase of Sepsis
inferredcites →https://doi.org/10.1128/jvi.00527-07openalex-snapshot
Interferon-Mediated Immunopathological Events Are Associated with Atypical Innate and Adaptive Immune Responses in Patients with Severe Acute Respiratory Syndrome
inferredcites →https://doi.org/10.1164/rccm.201308-1535ocopenalex-snapshot
Simultaneous Targeting of IL-1 and IL-18 Is Required for Protection against Inflammatory and Septic Shock
inferredcites →https://doi.org/10.1186/1471-2105-7-225openalex-snapshot
JColorGrid: software for the visualization of biological measurements
inferredcites →https://doi.org/10.1186/cc13046openalex-snapshot
Preliminary results in quantitation of HLA-DRA by real-time PCR: a promising approach to identify immunosuppression in sepsis
inferredcites →https://doi.org/10.1186/cc13049openalex-snapshot
Neutrophils from critically ill septic patients mediate profound loss of endothelial barrier integrity
inferredcites →https://doi.org/10.1186/cc13910openalex-snapshot
Quantification of IgM molecular response by droplet digital PCR as a potential tool for the early diagnosis of sepsis
inferredcites →https://doi.org/10.1186/cc9259openalex-snapshot
Host adaptive immunity deficiency in severe pandemic influenza
inferredcites →https://doi.org/10.1186/cc9392openalex-snapshot
Genome-wide transcription profiling of human sepsis: a systematic review
inferredcites →https://doi.org/10.1371/journal.pone.0017186openalex-snapshot
Aberrant Cell Cycle and Apoptotic Changes Characterise Severe Influenza A Infection – A Meta-Analysis of Genomic Signatures in Circulating Leukocytes
inferredcites →https://doi.org/10.1378/chest.101.6.1644openalex-snapshot
Definitions for Sepsis and Organ Failure and Guidelines for the Use of Innovative Therapies in Sepsis
inferredcites →https://doi.org/10.1586/eri.12.50openalex-snapshot
Sepsis, severe sepsis and septic shock: changes in incidence, pathogens and outcomes
inferredcites →https://doi.org/10.4049/jimmunol.158.11.5400openalex-snapshot
Adenosine inhibits neutrophil degranulation in activated human whole blood: involvement of adenosine A2 and A3 receptors
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Endothelial dysfunction is an early indicator of sepsis and neutrophil degranulation of septic shock in surgical patients
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Identification of diagnostic candidate genes in COVID‐19 patients with sepsis
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GATA3 mediates the cardioprotective effect of hydroxysafflor yellow a against septic cardiomyopathy: insights from integrated machine learning, WGCNA, and experimental validation
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MiR-608 Exerts Anti-inflammatory Effects by Targeting ELANE in Monocytes
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Low expression of the CCL5 gene and low serum concentrations of CCL5 in severe invasive group a streptococcal disease
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Genetic Factors of the Disease Course after Sepsis: A Genome-Wide Study for 28Day Mortality
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Predictive gene expression signature diagnoses neonatal sepsis before clinical presentation
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Transcriptomic analysis of key genes and signaling pathways in sepsis-associated intestinal mucosal barrier damage
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Whole transcriptome sequencing identifies key characteristics and potential therapeutic efficacy biomarkers CD1B, CD247, and CCNB1 in cured tuberculosis patients
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The novel role of LCK and other PcDEGs in the diagnosis and prognosis of sepsis: Insights from bioinformatic identification and experimental validation
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Impact of the pre-illness lipid profile on sepsis mortality
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Distinguishing septic shock from non-septic shock in postsurgical patients using gene expression
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CEACAM7 polymorphisms predict genetic predisposition to mortality in post-surgical septic shock patients
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Janus face of complement-driven neutrophil activation during sepsis
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Risk assessment with gene expression markers in sepsis development
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A community approach to mortality prediction in sepsis via gene expression analysis
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Immune resilience despite inflammatory stress promotes longevity and favorable health outcomes including resistance to infection
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A 6-mRNA host response classifier in whole blood predicts outcomes in COVID-19 and other acute viral infections
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Prospective validation of an 11-gene mRNA host response score for mortality risk stratification in the intensive care unit
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Exosomal hsa_circRNA_104484 and hsa_circRNA_104670 may serve as potential novel biomarkers and therapeutic targets for sepsis
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Identification of hub genes for adult patients with sepsis via RNA sequencing
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A gene network database for the identification of key genes for diagnosis, prognosis, and treatment in sepsis
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Use of Immune Profiling Panel to assess the immune response of septic patients for prediction of worsening as a composite endpoint
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Effect of acute exercise on gene expression in peripheral blood mononuclear cells of puberty children
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Systemic viral spreading and defective host responses are associated with fatal Lassa fever in macaques
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Factors Influencing Glucocorticoid Treatment Response: Mechanism-Based Strategies to Overcome Glucocorticoid Resistance and Restore GRα Function
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IL-1R1rs6755229 polymorphism is related to death in patients undergoing major surgery who develop septic shock: a retrospective study
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bvnGPS: a generalizable diagnostic model for acute bacterial and viral infection using integrative host transcriptomics and pretrained neural networks
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Neurogenomic Signatures of Successes and Failures in Life-History Transitions in a Key Insect Pollinator
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Multicohort Analysis of Whole-Blood Gene Expression Data Does Not Form a Robust Diagnostic for Acute Respiratory Distress Syndrome
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Unsupervised Analysis of Transcriptomics in Bacterial Sepsis Across Multiple Datasets Reveals Three Robust Clusters
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Gene Expression Scoring of Immune Activity Levels for Precision Use of Hydrocortisone in Vasodilatory Shock
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EXPLORING THE PROGNOSTIC NECROPTOSIS-RELATED GENES AND UNDERLYING MECHANISM IN SEPSIS USING BIOINFORMATICS
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Quantification of Immune Dysregulation by Next-generation Polymerase Chain Reaction to Improve Sepsis Diagnosis in Surgical Patients
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A 6-mRNA host response whole-blood classifier trained on pre-pandemic data accurately predicts severity in COVID-19 and other acute viral infections
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PathGPS: An Integrated Deep Learning and Machine Learning Framework for Multi-Pathogen Diagnosis Via Gene Pair Signatures
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Gene Co-Expression Networks Offer New Perspectives on Sepsis Pathophysiology
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Identification of Natural Killer Cell‐Related Genes as Potential Diagnostic Biomarkers for Pediatric Sepsis
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The long pentraxin PTX 3: A prototypical sensor of tissue injury and a regulator of homeostasis
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Data‐independent acquisition‐based quantitative proteomic analysis reveals differences in host immune response of peripheral blood mononuclear cells to sepsis
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Virus-induced genetics revealed by multidimensional precision medicine transcriptional workflow applicable to COVID-19
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Downregulation of miR‐497‐5p Improves Sepsis‐Induced Acute Lung Injury by Targeting IL2RB
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Identification of Immune-Related Genes in Sepsis due to Community-Acquired Pneumonia
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Screening of Sepsis Biomarkers Based on Bioinformatics Data Analysis
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Analysis of Sepsis Markers and Pathogenesis Based on Gene Differential Expression and Protein Interaction Network
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Metabolomics in Sepsis and Its Impact on Public Health
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Molecular Biomarker to Assist in Diagnosing Abdominal Sepsis upon ICU Admission
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Anti–miR-93-5p therapy prolongs sepsis survival by restoring the peripheral immune response
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Exploring the biomarkers and potential therapeutic drugs for sepsis via integrated bioinformatic analysis
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Bioinformatics prediction and experimental verification identify MAD2L1 and CCNB2 as diagnostic biomarkers of rhabdomyosarcoma
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Transcriptional pathways of terminal differentiation in high- and low-density blood granulocytes in sepsis
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Deciphering the molecular and cellular atlas of immune cells in septic patients with different bacterial infections
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Identification of a transcriptome profile associated with improvement of organ function in septic shock patients after early supportive therapy
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Host-pathogen interaction during mechanical ventilation: systemic or compartmentalized response?
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Composed endotypes to guide antibiotic discontinuation in sepsis
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A longitudinal study highlights shared aspects of the transcriptomic response to cardiogenic and septic shock
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Gene expression profile analysis of severe influenza-based modulation of idiopathic pulmonary fibrosis
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A meta-analysis of whole blood transcriptome reveals genes associated with increased neutrophil activity and T cell suppression in sepsis
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Transcriptomic Analysis of Key Genes and Signaling Pathways in Sepsis-Associated Intestinal Mucosal Barrier Damage
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Evidence of Active Pro-Fibrotic Response in Blood of Patients with Cirrhosis
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Evaluation of mRNA Biomarkers to Identify Risk of Hospital Acquired Infections in Children Admitted to Paediatric Intensive Care Unit
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Transcriptomic depression of immunological synapse as a signature of ventilator-associated pneumonia
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PRTN3/FCER1A Transcriptomic Ratio Predicts Hospitalization in Primary Care Attenders With Respiratory Infection
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Identification of hub genes for adult patients with sepsis via construction of a microRNA-mRNA-PPI network
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Six-gene Signature Based on Metabolism Is Closely Related to the Prognosis and Immune Infiltration of Patients With Sepsis
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Evaluation and validation of the increased annexin A3 (ANXA3) as a novel biomarker to predict sepsis in critically ill patients
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Construction of gene network database, and identification of key genes for diagnosis, prognosis, and treatment in sepsis
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Machine learning driven identification of gene-expression signatures correlated with multiple organ dysfunction trajectories and complex sub-endotypes of pediatric septic shock
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WITHDRAWN: Identification of platelets related THBS1 as a critical gene in sepsis related thrombocytopenia via an integrated bioinformatic analysis
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GENOMIC MEDICINE AND PERSONALIZED MANAGEMENT OF SEPSIS
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Recent Developments in Severe Sepsis Research: From Bench to Bedside and Back
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Combined Transcriptome and Proteome Leukocyte’s Profiling Reveals Up-Regulated Module of Genes/Proteins Related to Low Density Neutrophils and Impaired Transcription and Translation Processes in Clinical Sepsis
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Key Signature Genes of Early Terminal Granulocytic Differentiation Distinguish Sepsis From Systemic Inflammatory Response Syndrome on Intensive Care Unit Admission
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Construction and validation of a robust prognostic model based on immune features in sepsis
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IL7R, GZMA and CD8A serve as potential molecular biomarkers for sepsis based on bioinformatics analysis
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Mortality Prediction in Sepsis With an Immune-Related Transcriptomics Signature: A Multi-Cohort Analysis
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Whole blood ratio of CDK1/CX3CR1 mRNA expression combined to lactate refines the prediction of ICU mortality in septic patients in the Sepsis-3 era: a proof-of-concept study
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Identification and validation of novel candidate genes with diagnostic value for sepsis via weighted gene co-expression network analysis
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Endothelial Dysfunction and Neutrophil Degranulation as Central Events in Sepsis Physiopathology
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Immune-Related Molecules CD3G and FERMT3: Novel Biomarkers Associated with Sepsis
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Gene Expression Dysregulation in Whole Blood of Patients with Clostridioides difficile Infection
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Gene Expression Patterns Distinguish Mortality Risk in Patients with Postsurgical Shock
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Marcadores granulocíticos para diagnóstico, estratificación de gravedad y pronóstico en la infección.
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Huella molecular para el diagnóstico diferencial de pacientes sépticos y estimación del riesgo de mortalidad en pacientes con shock posquirúrgico.
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[Master genes and co-expression network analysis in peripheral blood mononuclear cells of patients with gram-positive and gram-negative sepsis].
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Additional file 1 of Exploring the biomarkers and potential therapeutic drugs for sepsis via integrated bioinformatic analysis
inferred← citeshttps://doi.org/10.6084/m9.figshare.24934650openalex-snapshot
Additional file 2 of Exploring the biomarkers and potential therapeutic drugs for sepsis via integrated bioinformatic analysis
inferred← citeshttps://doi.org/10.6084/m9.figshare.26634876openalex-snapshot
Additional file 1 of Deciphering the molecular and cellular atlas of immune cells in septic patients with different bacterial infections
inferred← citeshttps://doi.org/10.6084/m9.figshare.26634879openalex-snapshot
Additional file 2 of Deciphering the molecular and cellular atlas of immune cells in septic patients with different bacterial infections
inferred← citeshttps://doi.org/10.6084/m9.figshare.26658985openalex-snapshot
Additional file 3 of Exploring the biomarkers and potential therapeutic drugs for sepsis via integrated bioinformatic analysis
inferred← citeshttps://doi.org/10.6084/m9.figshare.26658988openalex-snapshot
Additional file 4 of Exploring the biomarkers and potential therapeutic drugs for sepsis via integrated bioinformatic analysis
inferred← citeshttps://doi.org/10.70675/7792f253z61fdz49d8z9ba5z7f5cdc7df666openalex-snapshot
Analyse comparative des mécanismes pathogéniques et protecteurs au cours de la fièvre de Lassa chez le singe cynomolgus
inferred← citeshttps://doi.org/10.7717/peerj.3915openalex-snapshot
Pulmonary transcriptomic responses indicate a dual role of inflammation in pneumonia development and viral clearance during 2009 pandemic influenza infection
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