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Mitochondria, metabolic disturbances, oxidative stress and the kynurenine system, with focus on neurodegenerative disorders
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inferredcites →https://doi.org/10.1002/(sici)1096-9861(19970728)384:2<312::aid-cne10>3.0.co;2-kopenalex-snapshot
Neocortical neuron number in humans: Effect of sex and age
inferredcites →https://doi.org/10.1002/ajmg.1425openalex-snapshot
Mitochondria and degenerative disorders
inferredcites →https://doi.org/10.1002/ana.10483openalex-snapshot
Oxidative stress in Parkinson's disease
inferredcites →https://doi.org/10.1002/ana.410240417openalex-snapshot
Cerebrospinal fluid levels of quinolinic acid in Huntington's disease and schizophrenia
inferredcites →https://doi.org/10.1002/ana.410340416openalex-snapshot
Oxidative damage to mitochondrial DNA shows marked age‐dependent increases in human brain
inferredcites →https://doi.org/10.1002/ana.410380304openalex-snapshot
Aging, energy, and oxidative stress in neurodegenerative diseases
inferredcites →https://doi.org/10.1002/ana.410390317openalex-snapshot
Mitochondrial defect in Huntington's disease caudate nucleus
inferredcites →https://doi.org/10.1002/ana.410410514openalex-snapshot
Oxidative damage and metabolic dysfunction in Huntington's disease: Selective vulnerability of the basal ganglia
inferredcites →https://doi.org/10.1002/cne.903210313openalex-snapshot
Localization of kynurenine aminotransferase immunoreactivity in the rat hippocampus
inferredcites →https://doi.org/10.1002/jnr.490360508openalex-snapshot
Glutamate neurotoxicity in mesencephalic dopaminergic neurons in culture
inferredcites →https://doi.org/10.1006/abbi.1996.0146openalex-snapshot
Nitric Oxide Inhibits Electron Transfer and Increases Superoxide Radical Production in Rat Heart Mitochondria and Submitochondrial Particles
inferredcites →https://doi.org/10.1006/exnr.1998.6767openalex-snapshot
Chronic Administration of Quinolinic Acid in the Rat Striatum Causes Spatial Learning Deficits in a Radial Arm Water Maze Task
inferredcites →https://doi.org/10.1007/978-1-4615-4709-9_17openalex-snapshot
Modulation and Function of Kynurenic Acid in the Immature Rat Brain
inferredcites →https://doi.org/10.1007/978-1-4615-4709-9_19openalex-snapshot
Degradation of Tryptophan in Neurodegenerative Disorders
inferredcites →https://doi.org/10.1007/bf00966592openalex-snapshot
Quinolinic acid is a potent lipid peroxidant in rat brain homogenates
inferredcites →https://doi.org/10.1007/bf01799110openalex-snapshot
Mitochondrial encephalomyopathies: what next?
inferredcites →https://doi.org/10.1007/s002100000325openalex-snapshot
Pharmacologically elevated levels of endogenous kynurenic acid prevent nicotine-induced activation of nigral dopamine neurons
inferredcites →https://doi.org/10.1007/s00702-002-0770-zopenalex-snapshot
Kynurenate production by cultured human astrocytes
inferredcites →https://doi.org/10.1007/s007020050149openalex-snapshot
Kynurenine metabolism in Alzheimer's disease
inferredcites →https://doi.org/10.1007/s007020200020openalex-snapshot
Effect of systemic L-DOPA administration on extracellular kynurenate levels in the rat striatum
inferredcites →https://doi.org/10.1016/0005-2728(96)00077-1openalex-snapshot
Mitochondrial oxidative phosphorylation changes in the life span. Molecular aspects and physiopathological implications
inferredcites →https://doi.org/10.1016/0006-8993(82)91048-4openalex-snapshot
An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid
inferredcites →https://doi.org/10.1016/0006-8993(88)90815-3openalex-snapshot
Identification and quantification of kynurenic acid in human brain tissue
inferredcites →https://doi.org/10.1016/0006-8993(91)91583-mopenalex-snapshot
Two kynurenine aminotransferases in human brain
inferredcites →https://doi.org/10.1016/0014-2999(81)90587-2openalex-snapshot
Quinolinic acid: A potent endogenous excitant at amino acid receptors in CNS
inferredcites →https://doi.org/10.1016/0014-2999(88)90367-6openalex-snapshot
Kynurenic acid antagonises responses to NMDA via an action at the strychnine-insensitive glycine receptor
inferredcites →https://doi.org/10.1016/0014-2999(91)90436-topenalex-snapshot
Comparative behavioral and pharmacological studies with centrally administered kynurenine and kynurenic acid in rats
inferredcites →https://doi.org/10.1016/0014-4886(84)90239-5openalex-snapshot
Studies on the disposition of quinolinic acid after intracerebral or systemic administration in the rat
inferredcites →https://doi.org/10.1016/0014-4886(85)90072-xopenalex-snapshot
Actions of kynurenic acid and quinolinic acid in the rat hippocampus in vivo
inferredcites →https://doi.org/10.1016/0022-510x(92)90191-mopenalex-snapshot
Kynurenic acid concentrations are reduced in Huntington's disease cerebral cortex
inferredcites →https://doi.org/10.1016/0022-510x(94)00280-2openalex-snapshot
Dysfunction of brain kynurenic acid metabolism in Huntington's disease: focus on kynurenine aminotransferases
inferredcites →https://doi.org/10.1016/0024-3205(84)90148-6openalex-snapshot
II. Excitotoxic models for neurodegenerative disorders
inferredcites →https://doi.org/10.1016/0024-3205(96)00173-7openalex-snapshot
Increased kynurenic acid levels and decreased brain kynurenine aminotransferasei in patients with down syndrome
inferredcites →https://doi.org/10.1016/0028-3908(93)90171-xopenalex-snapshot
Intravenous administration of L-kynurenine to rhesus monkeys: Effect on quinolinate and kynurenate levels in serum and cerebrospinal fluid
inferredcites →https://doi.org/10.1016/0163-1047(93)90145-8openalex-snapshot
7-Chlorokynurenate, an antagonist of the glycine binding site on the NMDA receptor, inhibits memory formation in day-old chicks (Gallus domesticus)
inferredcites →https://doi.org/10.1016/0166-2236(94)90102-3openalex-snapshot
Free radicals and neurodegeneration
inferredcites →https://doi.org/10.1016/0197-0186(95)00091-7openalex-snapshot
THE ENDOGENEOUS AGONIST QUINOLINIC ACID AND THE NON ENDOGENOUS HOMOQUINOLINIC ACID DISCRIMINATE BETWEEN NMDAR2 RECEPTOR SUBUNITS
inferredcites →https://doi.org/10.1016/0304-3940(88)90285-6openalex-snapshot
Kynurenic acid is present in the rat brain and its content increases during development and aging processes
inferredcites →https://doi.org/10.1016/0304-3940(89)90831-8openalex-snapshot
Effect of glycine and glycine receptor antagonists on NMDA-induced brain injury
inferredcites →https://doi.org/10.1016/0304-4157(84)90012-1openalex-snapshot
Organic ion transport during seven decades the amino acids
inferredcites →https://doi.org/10.1016/0306-4522(85)90063-6openalex-snapshot
Quinolinic acid and other kynurenines in the central nervous system
inferredcites →https://doi.org/10.1016/0306-4522(88)90156-xopenalex-snapshot
Sparing of cholinergic neurons following quinolinic acid lesions of the rat striatum
inferredcites →https://doi.org/10.1016/0361-9230(90)90123-hopenalex-snapshot
Intracerebroventricular injection of kynurenic acid, but not kynurenine, induces ataxia and stereotyped behavior in rats
inferredcites →https://doi.org/10.1016/0361-9230(92)90184-yopenalex-snapshot
Kynurenine and probenecid inhibit pentylenetetrazol- and NMDLA-induced seizures and increase kynurenic acid concentrations in the brain
inferredcites →https://doi.org/10.1016/0925-4439(95)00024-xopenalex-snapshot
Mitochondrial decay in aging
inferredcites →https://doi.org/10.1016/j.biopha.2003.11.004openalex-snapshot
Neurodegenerative diseases and oxidative stress
inferredcites →https://doi.org/10.1016/j.cccn.2005.04.013openalex-snapshot
The effect of age on the enzyme activities of tryptophan metabolism along the kynurenine pathway in rats
inferredcites →https://doi.org/10.1016/j.ceca.2005.06.019openalex-snapshot
Endoplasmic reticulum stress response and neurodegeneration
inferredcites →https://doi.org/10.1016/j.coph.2003.10.006openalex-snapshot
The kynurenine pathway of tryptophan degradation as a drug target
inferredcites →https://doi.org/10.1016/j.dnarep.2005.03.002openalex-snapshot
Role of mitochondrial DNA in toxic responses to oxidative stress
inferredcites →https://doi.org/10.1016/j.ejphar.2005.02.043openalex-snapshot
Systemically administered glucosamine-kynurenic acid, but not pure kynurenic acid, is effective in decreasing the evoked activity in area CA1 of the rat hippocampus
inferredcites →https://doi.org/10.1016/j.expneurol.2004.08.021openalex-snapshot
Ubiquitin–proteasome system and Parkinson's diseases
inferredcites →https://doi.org/10.1016/j.expneurol.2005.07.004openalex-snapshot
Endogenous kynurenate controls the vulnerability of striatal neurons to quinolinate: Implications for Huntington's disease
inferredcites →https://doi.org/10.1016/j.febslet.2004.12.058openalex-snapshot
The aggravating role of the ubiquitin–proteasome system in neurodegeneration
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2005.07.010openalex-snapshot
Mitochondrial respiratory chain and free radical generation in stroke
inferredcites →https://doi.org/10.1016/j.jchromb.2005.04.023openalex-snapshot
Oxidative stress in brain aging, neurodegenerative and vascular diseases: An overview
inferredcites →https://doi.org/10.1016/j.mam.2004.02.014openalex-snapshot
Nitric oxide, complex I, and the modulation of mitochondrial reactive species in biology and disease
inferredcites →https://doi.org/10.1016/j.neulet.2006.03.051openalex-snapshot
Kynurenic acid has a dual action on AMPA receptor responses
inferredcites →https://doi.org/10.1016/j.neuropharm.2004.06.007openalex-snapshot
Kynurenine administered together with probenecid markedly inhibits pentylenetetrazol-induced seizures. An electrophysiological and behavioural study
inferredcites →https://doi.org/10.1016/j.neuroscience.2004.04.043openalex-snapshot
Decreased expression of kynurenine aminotransferase-I (KAT-I) in the substantia nigra of mice after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) treatment
inferredcites →https://doi.org/10.1016/j.pharmthera.2005.05.007openalex-snapshot
Role of nitric oxide in Parkinson's disease
inferredcites →https://doi.org/10.1016/j.pneurobio.2004.10.001openalex-snapshot
Protein quality control in Alzheimer's disease by the ubiquitin proteasome system
inferredcites →https://doi.org/10.1016/j.pneurobio.2005.06.004openalex-snapshot
Microglia and inflammation-mediated neurodegeneration: Multiple triggers with a common mechanism
inferredcites →https://doi.org/10.1016/j.tips.2004.03.005openalex-snapshot
Nuclear and mitochondrial conversations in cell death: PARP-1 and AIF signaling
inferredcites →https://doi.org/10.1016/j.tips.2005.02.005openalex-snapshot
Mitochondrial nitric oxide synthase
inferredcites →https://doi.org/10.1016/j.tips.2005.08.007openalex-snapshot
To be or not to be (inflamed) – is that the question in anti-inflammatory drug therapy of neurodegenerative disorders?
inferredcites →https://doi.org/10.1016/s0005-2728(00)00177-8openalex-snapshot
Mitochondrial bioenergetics in aging
inferredcites →https://doi.org/10.1016/s0005-2728(98)00168-6openalex-snapshot
Nitric oxide, mitochondria and neurological disease
inferredcites →https://doi.org/10.1016/s0006-291x(03)00809-xopenalex-snapshot
Selective degradation of oxidatively modified protein substrates by the proteasome
inferredcites →https://doi.org/10.1016/s0006-8993(99)02474-9openalex-snapshot
Effect of quinolinic acid on endogenous antioxidants in rat corpus striatum
inferredcites →https://doi.org/10.1016/s0014-2999(02)01842-3openalex-snapshot
Mitochondria, Ca2+ and neurodegenerative disease
inferredcites →https://doi.org/10.1016/s0014-2999(99)00196-xopenalex-snapshot
Tryptophan metabolism and brain function: focus on kynurenine and other indole metabolites
inferredcites →https://doi.org/10.1016/s0014-5793(99)01028-5openalex-snapshot
β‐Amyloid fragment 25–35 selectively decreases complex IV activity in isolated mitochondria
inferredcites →https://doi.org/10.1016/s0021-9258(19)45852-3openalex-snapshot
Possible Participation of Superoxide Anion in the Intestinal Tryptophan 2,3-Dioxygenase Reaction
inferredcites →https://doi.org/10.1016/s0022-3565(24)37160-5openalex-snapshot
Novel Systemically Active Antagonists of the Glycine Site of the N-Methyl-d-aspartate Receptor: Electrophysiological, Biochemical and Behavioral Characterization
inferredcites →https://doi.org/10.1016/s0022-3565(25)38782-3openalex-snapshot
Kynurenic acid and quinolinic acid act at N-methyl-D-aspartate receptors in the rat hippocampus.
inferredcites →https://doi.org/10.1016/s0022-510x(00)00343-9openalex-snapshot
Oxidative damage to mitochondrial DNA and activity of mitochondrial enzymes in chronic active lesions of multiple sclerosis
inferredcites →https://doi.org/10.1016/s0028-3908(01)00019-3openalex-snapshot
Oxidative stress induced-neurodegenerative diseases: the need for antioxidants that penetrate the blood brain barrier
inferredcites →https://doi.org/10.1016/s0041-0101(00)00156-2openalex-snapshot
Endogenous neurotoxins from tryptophan
inferredcites →https://doi.org/10.1016/s0092-8674(02)01012-7openalex-snapshot
The UCH-L1 Gene Encodes Two Opposing Enzymatic Activities that Affect α-Synuclein Degradation and Parkinson's Disease Susceptibility
inferredcites →https://doi.org/10.1016/s0140-6736(78)92517-5openalex-snapshot
CENTRAL CERVICAL CORD SYNDROME AFTER HEADING A FOOTBALL
inferredcites →https://doi.org/10.1016/s0140-6736(89)90987-2openalex-snapshot
INCREASED BRAIN 3-HYDROXYKYNURENINE IN HUNTINGTON'S DISEASE
inferredcites →https://doi.org/10.1016/s0140-6736(89)92145-4openalex-snapshot
MITOCHONDRIAL DNA MUTATIONS AS AN IMPORTANT CONTRIBUTOR TO AGEING AND DEGENERATIVE DISEASES
inferredcites →https://doi.org/10.1016/s0140-6736(89)92366-0openalex-snapshot
MITOCHONDRIAL COMPLEX I DEFICIENCY IN PARKINSON'S DISEASE
inferredcites →https://doi.org/10.1016/s0163-7258(98)00042-4openalex-snapshot
The Role of Excitotoxicity in Neurodegenerative Disease
inferredcites →https://doi.org/10.1016/s0165-0173(99)00007-7openalex-snapshot
Neuroglial activation repertoire in the injured brain: graded response, molecular mechanisms and cues to physiological function
inferredcites →https://doi.org/10.1016/s0165-5728(01)00418-0openalex-snapshot
Synthesis and release of neurotoxic kynurenine metabolites by human monocyte-derived macrophages
inferredcites →https://doi.org/10.1016/s0166-2236(00)01584-8openalex-snapshot
Energetics in the pathogenesis of neurodegenerative diseases
inferredcites →https://doi.org/10.1016/s0169-328x(98)00310-6openalex-snapshot
Free radical scavenger OPC-14117 attenuates quinolinic acid-induced NF-κB activation and apoptosis in rat striatum
inferredcites →https://doi.org/10.1016/s0169-409x(99)00069-1openalex-snapshot
Drug delivery to mitochondria: the key to mitochondrial medicine
inferredcites →https://doi.org/10.1016/s0188-4409(01)00316-2openalex-snapshot
The Molecular Bases of Alzheimer's Disease and Other Neurodegenerative Disorders
inferredcites →https://doi.org/10.1016/s0197-0186(01)00133-4openalex-snapshot
Quinolinic acid stimulates synaptosomal glutamate release and inhibits glutamate uptake into astrocytes
inferredcites →https://doi.org/10.1016/s0197-0186(02)00196-1openalex-snapshot
Neurodegenerative disorders of protein aggregation
inferredcites →https://doi.org/10.1016/s0272-6386(97)90306-1openalex-snapshot
Low whole blood and erythrocyte levels of glutathione in hemodialysis and peritoneal dialysis patients
inferredcites →https://doi.org/10.1016/s0278-5846(98)00070-0openalex-snapshot
Comparison of intrastriatal injections of quinolinic acid and 3-nitropropionic acid for use in animal models of Huntington's disease
inferredcites →https://doi.org/10.1016/s0301-0082(00)00032-0openalex-snapshot
Kynurenines in the CNS: from endogenous obscurity to therapeutic importance
inferredcites →https://doi.org/10.1016/s0301-0082(02)00127-2openalex-snapshot
An inflammatory review of Parkinson’s disease
inferredcites →https://doi.org/10.1016/s0301-0082(99)00005-2openalex-snapshot
Replicating Huntington's disease phenotype in experimental animals
inferredcites →https://doi.org/10.1016/s0304-3940(02)00735-8openalex-snapshot
1-Methyl-4-phenylpyridinium and 3-nitropropionic acid diminish cortical synthesis of kynurenic acid via interference with kynurenine aminotransferases in rats
inferredcites →https://doi.org/10.1016/s0304-3940(99)00036-1openalex-snapshot
Quinolinic acid lesion of the nigrostriatal pathway: effect on turning behaviour and protection by elevation of endogenous kynurenic acid in rattus norvegicus
inferredcites →https://doi.org/10.1016/s0306-4522(00)00030-0openalex-snapshot
Kynurenergic manipulations influence excitatory synaptic function and excitotoxic vulnerability in the rat hippocampus in vivo
inferredcites →https://doi.org/10.1016/s0306-4522(96)00223-0openalex-snapshot
Effects of α-phenyl-tert-butyl nitrone on neuronal survival and motor function following intrastriatal injections of quinolinate or 3-nitropropionate
inferredcites →https://doi.org/10.1016/s0306-4522(96)00655-0openalex-snapshot
Protection against quinolinic acid-mediated excitotoxicity in nigrostriatal dopaminergic neurons by endogenous kynurenic acid
inferredcites →https://doi.org/10.1016/s0306-4522(99)00239-0openalex-snapshot
Early effects of intrastriatal injections of quinolinic acid on microtubule-associated protein-2 and neuropeptides in rat basal ganglia
inferredcites →https://doi.org/10.1016/s0306-4522(99)00306-1openalex-snapshot
Effects of in vivo sodium azide administration on the immunohistochemical localization of kynurenine aminotransferase in the rat brain
inferredcites →https://doi.org/10.1016/s0531-5565(03)00185-2openalex-snapshot
Aging and molecular chaperones
inferredcites →https://doi.org/10.1016/s0891-5849(02)01327-8openalex-snapshot
Nitric oxide-induced mitochondrial dysfunction: implications for neurodegeneration
inferredcites →https://doi.org/10.1016/s0896-6273(03)00606-8openalex-snapshot
The Ubiquitin Proteasome System in Neurodegenerative Diseases
inferredcites →https://doi.org/10.1016/s0959-4388(96)80100-0openalex-snapshot
Mitochondria, free radicals, and neurodegeneration
inferredcites →https://doi.org/10.1016/s1353-8020(02)00021-4openalex-snapshot
Degeneration of neuronal cells due to oxidative stress—microglial contribution
inferredcites →https://doi.org/10.1017/s003358350000425xopenalex-snapshot
The NADH:ubiquinone oxidoreductase (complex I) of respiratory chains
inferredcites →https://doi.org/10.1023/a:1020949812581openalex-snapshot
Nω-Nitro-L-Arginine, a Nitric Oxide Synthase Inhibitor, Antagonizes Quinolinic Acid-Induced Neurotoxicity and Oxidative Stress in Rat Striatal Slices
inferredcites →https://doi.org/10.1038/12647openalex-snapshot
Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice
inferredcites →https://doi.org/10.1038/321168a0openalex-snapshot
Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid
inferredcites →https://doi.org/10.1038/35085008openalex-snapshot
Four deaths and a funeral: from caspases to alternative mechanisms
inferredcites →https://doi.org/10.1038/nrd1330openalex-snapshot
Neurodegenerative diseases and oxidative stress
inferredcites →https://doi.org/10.1042/bst0060123openalex-snapshot
Positive Identification of Kynurenine in Rat and Human Brain
inferredcites →https://doi.org/10.1046/j.0953-816x.2001.01592.xopenalex-snapshot
Presynaptic kynurenate‐sensitive receptors inhibit glutamate release
inferredcites →https://doi.org/10.1046/j.1471-4159.1994.63062179.xopenalex-snapshot
Cortical Cytochrome Oxidase Activity Is Reduced in Alzheimer's Disease
inferredcites →https://doi.org/10.1046/j.1471-4159.1995.64051965.xopenalex-snapshot
Effect of Peroxynitrite on the Mitochondrial Respiratory Chain: Differential Susceptibility of Neurones and Astrocytes in Primary Culture
inferredcites →https://doi.org/10.1046/j.1471-4159.1995.65062621.xopenalex-snapshot
Metabolism of [5‐3H]Kynurenine in the Rat Brain In Vivo: Evidence for the Existence of a Functional Kynurenine Pathway
inferredcites →https://doi.org/10.1046/j.1471-4159.1997.69062564.xopenalex-snapshot
Threshold Effects in Synaptosomal and Nonsynaptic Mitochondria from Hippocampal CA1 and Paramedian Neocortex Brain Regions
inferredcites →https://doi.org/10.1046/j.1471-4159.1998.71041464.xopenalex-snapshot
[3H]Homoquinolinate Binds to a Subpopulation of NMDA Receptors and to a Novel Binding Site
inferredcites →https://doi.org/10.1046/j.1471-4159.2001.00498.xopenalex-snapshot
Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection
inferredcites →https://doi.org/10.1046/j.1471-4159.2002.00955.xopenalex-snapshot
Effects of systemic and central nervous system localized inflammation on the contributions of metabolic precursors to the l ‐kynurenine and quinolinic acid pools in brain
inferredcites →https://doi.org/10.1054/ceca.2000.0167openalex-snapshot
Age-related structural and functional changes of brain mitochondria
inferredcites →https://doi.org/10.1055/s-0038-1657047openalex-snapshot
Effects of Antimycin A and 2-Deoxyglucose on Energy Metabolism in Washed Human Platelets
inferredcites →https://doi.org/10.1073/pnas.240347797openalex-snapshot
Parkin functions as an E2-dependent ubiquitin– protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1
inferredcites →https://doi.org/10.1073/pnas.261560998openalex-snapshot
Different responses of astrocytes and neurons to nitric oxide: The role of glycolytically generated ATP in astrocyte protection
inferredcites →https://doi.org/10.1073/pnas.87.4.1620openalex-snapshot
Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.
inferredcites →https://doi.org/10.1073/pnas.88.9.3633openalex-snapshot
Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity, and loss in temporal and spatial memory by chronic administration of the spin-trapping compound N-tert-butyl-alpha-phenylnitrone.
inferredcites →https://doi.org/10.1073/pnas.94.2.514openalex-snapshot
Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress
inferredcites →https://doi.org/10.1073/pnas.95.15.8892openalex-snapshot
Coenzyme Q 10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects
inferredcites →https://doi.org/10.1074/jbc.m204580200openalex-snapshot
The Modulation of Mitochondrial Nitric-oxide Synthase Activity in Rat Brain Development
inferredcites →https://doi.org/10.1074/jbc.m313579200openalex-snapshot
Proteasome Inhibition Alters Neural Mitochondrial Homeostasis and Mitochondria Turnover
inferredcites →https://doi.org/10.1080/15216549700202021openalex-snapshot
Membrane permeability transition as induced by dysfunction of the electron transport chain
inferredcites →https://doi.org/10.1093/brain/115.5.1249openalex-snapshot
QUINOLINIC ACID AND KYNURENINE PATHWAY METABOLISM IN INFLAMMATORY AND NON-INFLAMMATORY NEUROLOGICAL DISEASE
inferredcites →https://doi.org/10.1093/geronj/11.3.298openalex-snapshot
Aging: A Theory Based on Free Radical and Radiation Chemistry
inferredcites →https://doi.org/10.1097/00001756-199711100-00039openalex-snapshot
Immuno-localization of kynurenine aminotransferase (KAT) in the rat medulla and spinal cord
inferredcites →https://doi.org/10.1097/00001756-200103260-00049openalex-snapshot
Quinolinic acid induces oxidative stress in rat brain synaptosomes
inferredcites →https://doi.org/10.1097/00005344-200309000-00012openalex-snapshot
Effect of Systemic Administration of L-Kynurenine on Corticocerebral Blood Flow under Normal and Ischemic Conditions of the Brain in Conscious Rabbits
inferredcites →https://doi.org/10.1101/gad.13.10.1211openalex-snapshot
Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls
inferredcites →https://doi.org/10.1111/j.1365-2796.2005.01570.xopenalex-snapshot
Apoptosis: a basic biological phenomenon with wide‐ranging implications in human disease
inferredcites →https://doi.org/10.1111/j.1365-2990.2005.00655.xopenalex-snapshot
Indoleamine 2,3 dioxygenase and quinolinic acid Immunoreactivity in Alzheimer's disease hippocampus
inferredcites →https://doi.org/10.1111/j.1432-1033.1993.tb18025.xopenalex-snapshot
Strategies of antioxidant defense
inferredcites →https://doi.org/10.1111/j.1432-1033.1997.00710.xopenalex-snapshot
Modulation of the Mitochondrial Permeability Transition by Nitric Oxide
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Mitochondrial intermembrane junctional complexes and their role in cell death
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Brain Quinolinic Acid in Huntington's Disease
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Presence of Kynurenic Acid in the Mammalian Brain
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A Glycine Site Associated with N‐Methyl‐ d ‐Aspartic Acid Receptors: Characterization and Identification of a New Class of Antagonists
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Blood–Brain Barrier Transport of Kynurenines: Implications for Brain Synthesis and Metabolism
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Dopaminergic Control of Kynurenate Levels and N-Methyl-D-Aspartate Toxicity in the Developing Rat Striatum
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Characterisation of kynurenine pathway metabolism in human astrocytes and implications in neuropathogenesis
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Implications of the kynurenine pathway and quinolinic acid in Alzheimer's disease
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Kynurenine pathway abnormalities in Parkinson's disease
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Tryptophan Metabolites and Brain Disorders
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Kynurenic acid antagonists and kynurenine pathway inhibitors
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Cerebral synthesis and release of kynurenic acid: an endogenous antagonist of excitatory amino acid receptors
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Chronic quinolinic acid lesions in rats closely resemble Huntington's disease
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Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid
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inferred← citeshttps://doi.org/10.1016/j.ejmech.2009.04.007openalex-snapshot
Synthesis of some urea and thiourea derivatives of 3-phenyl/ethyl-2-thioxo-2,3-dihydrothiazolo[4,5-d]pyrimidine and their antagonistic effects on haloperidol-induced catalepsy and oxidative stress in mice
inferred← citeshttps://doi.org/10.1016/j.ejps.2016.02.012openalex-snapshot
Targeting of the kynurenic acid across the blood–brain barrier by core-shell nanoparticles
inferred← citeshttps://doi.org/10.1016/j.ensci.2020.100270openalex-snapshot
Kynurenine pathway in Parkinson's disease—An update
inferred← citeshttps://doi.org/10.1016/j.envpol.2024.123356openalex-snapshot
Bisphenol F exposure induces depression-like changes: Roles of the kynurenine metabolic pathway along the “liver-brain” axis
inferred← citeshttps://doi.org/10.1016/j.etap.2008.04.003openalex-snapshot
In vitro effect of manganese chloride exposure on energy metabolism and oxidative damage of mitochondria isolated from rat brain
inferred← citeshttps://doi.org/10.1016/j.eujim.2021.101338openalex-snapshot
Cytotoxicity and antioxidant activities of leaf extracts of Varthemia sericea (Batt. et Trab.) Diels
inferred← citeshttps://doi.org/10.1016/j.exger.2010.01.015openalex-snapshot
Different expression of α and β mitochondrial estrogen receptors in the aging rat brain: Interaction with respiratory complex V
inferred← citeshttps://doi.org/10.1016/j.expneurol.2010.01.002openalex-snapshot
Mitochondrial-dependent apoptosis in Huntington's disease human cybrids
inferred← citeshttps://doi.org/10.1016/j.expneurol.2015.08.012openalex-snapshot
Melanocortin receptor agonist ACTH 1–39 protects rat forebrain neurons from apoptotic, excitotoxic and inflammation-related damage
inferred← citeshttps://doi.org/10.1016/j.fct.2019.05.007openalex-snapshot
Phenolic composition, antioxidant and antibacterial properties, and in vitro anti-HepG2 cell activities of wild apricot (Armeniaca Sibirica L. Lam) kernel skins
inferred← citeshttps://doi.org/10.1016/j.foodres.2007.12.012openalex-snapshot
Polyphenols contents and antioxidant capacity of 68 Chinese herbals suitable for medical or food uses
inferred← citeshttps://doi.org/10.1016/j.foodres.2011.02.026openalex-snapshot
Polyphenols content and antioxidant capacity of thirteen faba bean (Vicia faba L.) genotypes cultivated in Tunisia
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2017.10.011openalex-snapshot
Metabolomic analysis of oxidative stress: Superoxide dismutase mutation and paraquat induced stress in Drosophila melanogaster
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2020.07.018openalex-snapshot
Protective effects of diallyl trisulfide (DATS) against doxorubicin-induced inflammation and oxidative stress in the brain of rats
inferred← citeshttps://doi.org/10.1016/j.fsi.2008.09.016openalex-snapshot
The role of electron transport in the defence response of the South African abalone, Haliotis midae
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e32188openalex-snapshot
C–3 alkoxymethylation of 4-oxo-1,4-dihydroquinoline 2-carboxylic acid esters via organic additives
inferred← citeshttps://doi.org/10.1016/j.humgen.2023.201209openalex-snapshot
Monitorization of autophagic flux in a rat model of lung ischemia-reperfusion injury — Insights on organ transplantation surgery
inferred← citeshttps://doi.org/10.1016/j.ijms.2010.06.036openalex-snapshot
Cardiolipin and oxidative stress: Identification of new short chain oxidation products of cardiolipin in in vitro analysis and in nephrotoxic drug-induced disturbances in rat kidney tissue
inferred← citeshttps://doi.org/10.1016/j.jad.2017.03.023openalex-snapshot
Genetic variants of the kynurenine-3-monooxygenase and postpartum depressive symptoms after cesarean section in Chinese women
inferred← citeshttps://doi.org/10.1016/j.jad.2019.05.028openalex-snapshot
Changes in tryptophan metabolism during pregnancy and postpartum periods: Potential involvement in postpartum depressive symptoms
inferred← citeshttps://doi.org/10.1016/j.jad.2019.07.045openalex-snapshot
Inflammatory markers and treatment outcome in treatment resistant depression: A systematic review
inferred← citeshttps://doi.org/10.1016/j.jadr.2023.100580openalex-snapshot
Common mechanisms involved in lung cancer and depression: The dominant role of interleukin-6-IDO pathway in the lung-brain axis
inferred← citeshttps://doi.org/10.1016/j.jbiosc.2013.12.009openalex-snapshot
Improved on-line high performance liquid chromatography method for detection of antioxidants in Eucommia ulmoides Oliver flower
inferred← citeshttps://doi.org/10.1016/j.jchromb.2008.08.010openalex-snapshot
Effect of a traditional Chinese medicine preparation Xindi soft capsule on rat model of acute blood stasis: A urinary metabonomics study based on liquid chromatography–mass spectrometry
inferred← citeshttps://doi.org/10.1016/j.jchromb.2015.07.046openalex-snapshot
Target-guided separation of antioxidants from Semen cassia via off-line two-dimensional high-speed counter-current chromatography combined with complexation and extrusion elution mode
inferred← citeshttps://doi.org/10.1016/j.jcrc.2021.09.025openalex-snapshot
Activation of the kynurenine pathway predicts mortality and neurological outcome in cardiac arrest patients: A validation study
inferred← citeshttps://doi.org/10.1016/j.jep.2013.10.042openalex-snapshot
Xiao-Xu-Ming decoction preserves mitochondrial integrity and reduces apoptosis after focal cerebral ischemia and reperfusion via the mitochondrial p53 pathway
inferred← citeshttps://doi.org/10.1016/j.jep.2015.12.011openalex-snapshot
A systems pharmacology approach to decipher the mechanism of danggui-shaoyao-san decoction for the treatment of neurodegenerative diseases
inferred← citeshttps://doi.org/10.1016/j.jep.2016.10.018openalex-snapshot
Antioxidant and in vivo genoprotective effects of phenolic compounds identified from an endophytic Cladosporium velox and their relationship with its host plant Tinospora cordifolia
inferred← citeshttps://doi.org/10.1016/j.jgeb.2025.100516openalex-snapshot
Phytochemical screening, antioxidant, and antimicrobial analysis of Portulaca oleracea seeds with in-silico molecular docking insights
inferred← citeshttps://doi.org/10.1016/j.jinorgbio.2018.12.010openalex-snapshot
Copper complexes for biomedical applications: Structural insights, antioxidant activity and neuron compatibility
inferred← citeshttps://doi.org/10.1016/j.jns.2010.08.001openalex-snapshot
Dementia, stroke and migraine — Some common pathological mechanisms
inferred← citeshttps://doi.org/10.1016/j.jns.2011.07.021openalex-snapshot
Altered tryptophan metabolism in Parkinson's disease: A possible novel therapeutic approach
inferred← citeshttps://doi.org/10.1016/j.jns.2012.08.005openalex-snapshot
The kynurenine pathway in neurodegenerative diseases: Mechanistic and therapeutic considerations
inferred← citeshttps://doi.org/10.1016/j.jns.2012.09.010openalex-snapshot
Vascular factors and epigenetic modifications in the pathogenesis of Alzheimer's disease
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2011.12.010openalex-snapshot
RETRACTED: Curcumin restores Nrf2 levels and prevents quinolinic acid-induced neurotoxicity
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2018.02.001openalex-snapshot
Beneficial effects of white wine polyphenols-enriched diet on Alzheimer’s disease-like pathology
inferred← citeshttps://doi.org/10.1016/j.jocn.2016.10.038openalex-snapshot
Protective effect of nicotinamide adenine dinucleotide (NAD+) against spinal cord ischemia–reperfusion injury via reducing oxidative stress-induced neuronal apoptosis
inferred← citeshttps://doi.org/10.1016/j.jsps.2012.05.002openalex-snapshot
Review on in vivo and in vitro methods evaluation of antioxidant activity
inferred← citeshttps://doi.org/10.1016/j.mad.2024.111901openalex-snapshot
Novel 18-norspirostane steroidal saponins: Extending lifespan and mitigating neurodegeneration through promotion of mitophagy and mitochondrial biogenesis in Caenorhabditis elegans
inferred← citeshttps://doi.org/10.1016/j.matpr.2020.03.719openalex-snapshot
Studies on synthesis and antioxidant property of anthraquinone analogues
inferred← citeshttps://doi.org/10.1016/j.matpr.2023.05.485openalex-snapshot
In vitro antioxidant activity and electro analytic approach on Indigofera tirunelvelica Sanjappa
inferred← citeshttps://doi.org/10.1016/j.mehy.2011.06.021openalex-snapshot
Stressor-induced NMDAR dysfunction as a unifying hypothesis for the aetiology, pathogenesis and comorbidity of clinical depression
inferred← citeshttps://doi.org/10.1016/j.micron.2009.08.010openalex-snapshot
A ketogenic diet increases succinic dehydrogenase (SDH) activity and recovers age-related decrease in numeric density of SDH-positive mitochondria in cerebellar Purkinje cells of late-adult rats
inferred← citeshttps://doi.org/10.1016/j.mito.2010.04.004openalex-snapshot
Coexistence of mitochondrial and nuclear DNA mutations in a woman with mitochondrial encephalomyopathy and double cortex
inferred← citeshttps://doi.org/10.1016/j.mito.2015.02.001openalex-snapshot
Mitochondrial iron homeostasis and its dysfunctions in neurodegenerative disorders
inferred← citeshttps://doi.org/10.1016/j.mito.2023.01.002openalex-snapshot
Mitochondrial dysfunction in cognitive neurodevelopmental disorders: Cause or effect?
inferred← citeshttps://doi.org/10.1016/j.molliq.2017.06.091openalex-snapshot
DNA interaction, molecular docking and biological profile of tetradentate histidine based metallointercalators
inferred← citeshttps://doi.org/10.1016/j.molstruc.2021.130952openalex-snapshot
Synthesis, characterization, biological evaluation, BSA binding properties, density functional theory and molecular docking study of Schiff bases
inferred← citeshttps://doi.org/10.1016/j.msard.2017.03.012openalex-snapshot
Terminalia chebula attenuates quinolinate-induced oxidative PC12 and OLN-93 cell death
inferred← citeshttps://doi.org/10.1016/j.neuint.2011.03.013openalex-snapshot
Different effects of intranigral and intrastriatal administration of the proteasome inhibitor lactacystin on typical neurochemical and histological markers of Parkinson's disease in rats
inferred← citeshttps://doi.org/10.1016/j.neures.2017.04.020openalex-snapshot
Increase of reactive oxygen species generation in cerebral cortex slices after the transiently enhanced metabolic activity
inferred← citeshttps://doi.org/10.1016/j.neuro.2009.12.008openalex-snapshot
Protective effect of rofecoxib and nimesulide against intra-striatal quinolinic acid-induced behavioral, oxidative stress and mitochondrial dysfunctions in rats
inferred← citeshttps://doi.org/10.1016/j.neuro.2012.11.007openalex-snapshot
3-Hydroxykynurenine: An intriguing molecule exerting dual actions in the Central Nervous System
inferred← citeshttps://doi.org/10.1016/j.neuro.2013.04.004openalex-snapshot
A comparative study of protein carbonylation and mitochondrial dysfunction using the neurotoxicants 1,3-dinitrobenzene, 3-nitropropionic acid, and 3-chloropropanediol
inferred← citeshttps://doi.org/10.1016/j.neuro.2013.05.002openalex-snapshot
Okadaic acid induced neurotoxicity: An emerging tool to study Alzheimer's disease pathology
inferred← citeshttps://doi.org/10.1016/j.neuro.2014.03.012openalex-snapshot
Short-term effects of a perinatal exposure to a 16 polycyclic aromatic hydrocarbon mixture in rats: Assessment of early motor and sensorial development and cerebral cytochrome oxidase activity in pups
inferred← citeshttps://doi.org/10.1016/j.neuropharm.2013.02.006openalex-snapshot
The neuroprotector kynurenic acid increases neuronal cell survival through neprilysin induction
inferred← citeshttps://doi.org/10.1016/j.neuropharm.2014.07.002openalex-snapshot
Mitochondria autophagy is induced after hypoxic/ischemic stress in a Drp1 dependent manner: The role of inhibition of Drp1 in ischemic brain damage
inferred← citeshttps://doi.org/10.1016/j.neuropharm.2016.03.013openalex-snapshot
Kynurenine pathway metabolites and enzymes involved in redox reactions
inferred← citeshttps://doi.org/10.1016/j.neuropharm.2016.03.024openalex-snapshot
Recent evidence for an expanded role of the kynurenine pathway of tryptophan metabolism in neurological diseases
inferred← citeshttps://doi.org/10.1016/j.neuropharm.2016.05.011openalex-snapshot
Involvement of quinolinic acid in the neuropathogenesis of amyotrophic lateral sclerosis
inferred← citeshttps://doi.org/10.1016/j.neuropharm.2026.110923openalex-snapshot
Ajugol ameliorates mitochondrial dysfunction and cognitive decline in Alzheimer's Disease via BNIP3-dependent mitophagy
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2010.08.039openalex-snapshot
Protective effect of montelukast against quinolinic acid/malonic acid induced neurotoxicity: possible behavioral, biochemical, mitochondrial and tumor necrosis factor-α level alterations in rats
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2012.11.062openalex-snapshot
Mitochondrial bioenergetic deficits in the hippocampi of rats with chronic ischemia-induced vascular dementia
inferred← citeshttps://doi.org/10.1016/j.pbb.2009.08.001openalex-snapshot
Valproate ameliorates the survival and the motor performance in a transgenic mouse model of Huntington's disease
inferred← citeshttps://doi.org/10.1016/j.pbb.2012.04.009openalex-snapshot
Melamine induced cognitive impairment associated with oxidative damage in rat's hippocampus
inferred← citeshttps://doi.org/10.1016/j.phymed.2009.01.007openalex-snapshot
Protections of SMND-309, a novel derivate of salvianolic acid B, on brain mitochondria contribute to injury amelioration in cerebral ischemia rats
inferred← citeshttps://doi.org/10.1016/j.pneurobio.2010.04.004openalex-snapshot
Eating ourselves to death (and despair): The contribution of adiposity and inflammation to depression
inferred← citeshttps://doi.org/10.1016/j.pnpbp.2015.09.003openalex-snapshot
Maternal separation induces neuroinflammation and long-lasting emotional alterations in mice
inferred← citeshttps://doi.org/10.1016/j.psyneuen.2019.04.006openalex-snapshot
Activation of the kynurenine pathway and mitochondrial respiration to face allostatic load in a double-hit model of stress
inferred← citeshttps://doi.org/10.1016/j.redox.2015.11.010openalex-snapshot
Interplay between oxidant species and energy metabolism
inferred← citeshttps://doi.org/10.1016/j.resuscitation.2013.06.002openalex-snapshot
Early kynurenine pathway activation following cardiac arrest in rats, pigs, and humans
inferred← citeshttps://doi.org/10.1016/j.sajb.2021.06.001openalex-snapshot
Phytochemical content and antioxidant potential of leaf extracts of Citrus limon (L.) Osbeck collected in the Eastern Cape Province, South Africa
inferred← citeshttps://doi.org/10.1016/j.sjbs.2018.08.010openalex-snapshot
The potential of antioxidant activity of methanolic extract of Coscinium fenestratum (Goetgh.) Colebr (Menispermaceae)
inferred← citeshttps://doi.org/10.1016/j.tet.2015.09.014openalex-snapshot
Synthesis of triphenylphosphonium vitamin E derivatives as mitochondria-targeted antioxidants
inferred← citeshttps://doi.org/10.1016/j.toxlet.2012.03.005openalex-snapshot
Late effects of a perinatal exposure to a 16 PAH mixture: Increase of anxiety-related behaviours and decrease of regional brain metabolism in adult male rats
inferred← citeshttps://doi.org/10.1016/j.toxlet.2016.02.018openalex-snapshot
Characterization of urinary metabolites as biomarkers of colistin-induced nephrotoxicity in rats by a liquid chromatography/mass spectrometry-based metabolomics approach
inferred← citeshttps://doi.org/10.1016/j.ultrasmedbio.2016.04.019openalex-snapshot
Non-Invasive, Focal Disconnection of Brain Circuitry Using Magnetic Resonance-Guided Low-Intensity Focused Ultrasound to Deliver a Neurotoxin
inferred← citeshttps://doi.org/10.1016/j.ultrasmedbio.2017.04.020openalex-snapshot
Neuroprotective Effect of Low-Intensity Pulsed Ultrasound Against MPP + -Induced Neurotoxicity in PC12 Cells: Involvement of K2P Channels and Stretch-Activated Ion Channels
inferred← citeshttps://doi.org/10.1016/s2305-0500(13)60072-xopenalex-snapshot
Beneficial effect of food supplementation with the nutriceutical Improve® for the treatment of infertile couple
inferred← citeshttps://doi.org/10.1017/neu.2016.69openalex-snapshot
Inflammation and depression: a causal or coincidental link to the pathophysiology?
inferred← citeshttps://doi.org/10.1017/neu.2019.17openalex-snapshot
Inflammation, insulin resistance and neuroprogression in depression
inferred← citeshttps://doi.org/10.1021/acsanm.2c05400openalex-snapshot
Palladium/Rhodium/Iridium Trimetallic Octahedral Nanozymes Exhibiting Enhanced Peroxidase-like Activity for Detecting Total Antioxidant Capacity in Food
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