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Retinoic acid induced-1 (Rai1) regulates craniofacial and brain development in Xenopus

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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1001/archneur.1990.00530050049011openalex-snapshot
Anomalous Brain Morphology on Magnetic Resonance Images in Williams Syndrome and Down Syndrome
inferredcites →https://doi.org/10.1002/9780470479216.corpsy0709openalex-snapshot
Principal Component Analysis
inferredcites →https://doi.org/10.1002/ajmg.a.31510openalex-snapshot
RAI1 point mutations, CAG repeat variation, and SNP analysis in non‐deletion Smith–Magenis syndrome
inferredcites →https://doi.org/10.1002/ajmg.c.30275openalex-snapshot
Autism spectrum features in Smith–Magenis syndrome
inferredcites →https://doi.org/10.1002/ar.22864openalex-snapshot
Quantitative Analysis of Orofacial Development and Median Clefts in Xenopus Laevis
inferredcites →https://doi.org/10.1002/bdra.20793openalex-snapshot
Xenopus: An emerging model for studying congenital heart disease
inferredcites →https://doi.org/10.1002/bies.200800207openalex-snapshot
Totally tubular: the mystery behind function and origin of the brain ventricular system
inferredcites →https://doi.org/10.1002/cphy.c120021openalex-snapshot
Zebrafish Models of Human Liver Development and Disease
inferredcites →https://doi.org/10.1002/dvdy.20231openalex-snapshot
Global analysis of RAR‐responsive genes in the Xenopus neurula using cDNA microarrays
inferredcites →https://doi.org/10.1002/dvg.20286openalex-snapshot
Decoding development in Xenopus tropicalis
inferredcites →https://doi.org/10.1002/dvg.22015openalex-snapshot
Xenopus white papers and resources: Folding functional genomics and genetics into the frog
inferredcites →https://doi.org/10.1002/neu.20272openalex-snapshot
Retinoic acid and hindbrain patterning
inferredcites →https://doi.org/10.1002/path.1289openalex-snapshot
Comparison of immunohistochemistry for activated caspase‐3 and cleaved cytokeratin 18 with the TUNEL method for quantification of apoptosis in histological sections of PC‐3 subcutaneous xenografts
inferredcites →https://doi.org/10.1002/wics.101openalex-snapshot
Principal component analysis
inferredcites →https://doi.org/10.1006/dbio.2002.0819openalex-snapshot
The Role of Neural Crest during Cardiac Development in a Mouse Model of DiGeorge Syndrome
inferredcites →https://doi.org/10.1007/978-1-4615-4685-6_22openalex-snapshot
Neurotrophins in Cell Survival/Death Decisions
inferredcites →https://doi.org/10.1007/978-1-61779-523-7_4openalex-snapshot
Morpholino Injection in Xenopus
inferredcites →https://doi.org/10.1007/s00335-009-9180-yopenalex-snapshot
Abnormal maternal behavior, altered sociability, and impaired serotonin metabolism in Rai1-transgenic mice
inferredcites →https://doi.org/10.1016/0002-9394(82)90358-0openalex-snapshot
Oculocutaneous Albinoidism as a Manifestation of Reduced Neural Crest Derivatives in the Prader-Willi Syndrome
inferredcites →https://doi.org/10.1016/0169-328x(95)00020-sopenalex-snapshot
Cloning of a retinoic acid-induced gene, GT1, in the embryonal carcinoma cell line P19: neuron-specific expression in the mouse brain
inferredcites →https://doi.org/10.1016/j.alcohol.2009.10.016openalex-snapshot
Prenatal alcohol exposure alters the patterns of facial asymmetry
inferredcites →https://doi.org/10.1016/j.cbpc.2011.06.010openalex-snapshot
Aquatic animal models of human disease: Selected papers from the 5th Conference
inferredcites →https://doi.org/10.1016/j.gde.2004.07.012openalex-snapshot
Retinoic acid signalling in the development of branchial arches
inferredcites →https://doi.org/10.1016/j.mod.2008.11.002openalex-snapshot
A neural crest deficit in Down syndrome mice is associated with deficient mitotic response to Sonic hedgehog
inferredcites →https://doi.org/10.1016/j.mod.2012.06.001openalex-snapshot
Williams Syndrome Transcription Factor is critical for neural crest cell function in Xenopus laevis
inferredcites →https://doi.org/10.1016/j.ydbio.2006.03.054openalex-snapshot
Development of the primary mouth in Xenopus laevis
inferredcites →https://doi.org/10.1016/j.ydbio.2008.12.029openalex-snapshot
Why the embryo still matters: CSF and the neuroepithelium as interdependent regulators of embryonic brain growth, morphogenesis and histiogenesis
inferredcites →https://doi.org/10.1016/j.ydbio.2012.02.033openalex-snapshot
Median facial clefts in Xenopus laevis: Roles of retinoic acid signaling and homeobox genes
inferredcites →https://doi.org/10.1016/j.yexcr.2012.03.006openalex-snapshot
Neurotrophins and cell death
inferredcites →https://doi.org/10.1016/j.ymeth.2010.08.001openalex-snapshot
Analysis of messenger RNA expression by in situ hybridization using RNA probes synthesized via in vitro transcription
inferredcites →https://doi.org/10.1016/s0168-9525(00)89129-5openalex-snapshot
Normal table of Xenopus laevis (Daudin)
inferredcites →https://doi.org/10.1016/s0925-4773(00)00558-xopenalex-snapshot
Increased XRALDH2 activity has a posteriorizing effect on the central nervous system of Xenopus embryos
inferredcites →https://doi.org/10.1034/j.1601-183x.2003.00038.xopenalex-snapshot
Can zebrafish be used as a model to study the neurodevelopmental causes of autism?
inferredcites →https://doi.org/10.1038/ng1126openalex-snapshot
Mutations in RAI1 associated with Smith–Magenis syndrome
inferredcites →https://doi.org/10.1038/sj.ejhg.5202009openalex-snapshot
Smith–Magenis syndrome
inferredcites →https://doi.org/10.1073/pnas.1010740107openalex-snapshot
Reiterative AP2a activity controls sequential steps in the neural crest gene regulatory network
inferredcites →https://doi.org/10.1074/jbc.m413863200openalex-snapshot
Neuritic Beading Induced by Activated Microglia Is an Early Feature of Neuronal Dysfunction Toward Neuronal Death by Inhibition of Mitochondrial Respiration and Axonal Transport
inferredcites →https://doi.org/10.1083/jcb.201011077openalex-snapshot
FGF and retinoic acid activity gradients control the timing of neural crest cell emigration in the trunk
inferredcites →https://doi.org/10.1083/jcb.201108111openalex-snapshot
Axon degeneration: Molecular mechanisms of a self-destruction pathway
inferredcites →https://doi.org/10.1086/512043openalex-snapshot
Penetrance of Craniofacial Anomalies in Mouse Models of Smith-Magenis Syndrome Is Modified by Genomic Sequence Surrounding Rai1: Not All Null Alleles Are Alike
inferredcites →https://doi.org/10.1091/mbc.e06-05-0419openalex-snapshot
The N-Terminal Transactivation Domain Confers Target Gene Specificity of Hypoxia-inducible Factors HIF-1α and HIF-2α
inferredcites →https://doi.org/10.1093/hmg/ddi085openalex-snapshot
Inactivation of Rai1 in mice recapitulates phenotypes observed in chromosome engineered mouse models for Smith–Magenis syndrome
inferredcites →https://doi.org/10.1093/hmg/ddm128openalex-snapshot
Rai1 deficiency in mice causes learning impairment and motor dysfunction, whereas Rai1 heterozygous mice display minimal behavioral phenotypes
inferredcites →https://doi.org/10.1093/hmg/ddq317openalex-snapshot
Rai1 haploinsufficiency causes reduced Bdnf expression resulting in hyperphagia, obesity and altered fat distribution in mice and humans with no evidence of metabolic syndrome
inferredcites →https://doi.org/10.1093/hmg/ddt568openalex-snapshot
Correct developmental expression level of Rai1 in forebrain neurons is required for control of body weight, activity levels and learning and memory
inferredcites →https://doi.org/10.1093/nar/19.13.3709openalex-snapshot
Developmental regulation of transcription factor AP-2 duringXenopus laevisembryogenesis
inferredcites →https://doi.org/10.1097/01.gim.0000228215.32110.89openalex-snapshot
Genotype–phenotype correlation in Smith-Magenis syndrome: Evidence that multiple genes in 17p11.2 contribute to the clinical spectrum
inferredcites →https://doi.org/10.1098/rstb.1996.0030openalex-snapshot
Role of neurotrophins and trk receptors in the development and maintenance of sensory neurons: an overview
inferredcites →https://doi.org/10.1101/gad.317405openalex-snapshot
Inactivation of TGFβ signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome
inferredcites →https://doi.org/10.1101/gr.9.2.99openalex-snapshot
Zebrafish: A New Model for Human Disease: Figure 1.
inferredcites →https://doi.org/10.1111/j.1755-0998.2010.02924.xopenalex-snapshot
Morpho J: an integrated software package for geometric morphometrics
inferredcites →https://doi.org/10.1124/mi.9.6.7openalex-snapshot
PHD Fingers: Epigenetic Effectors and Potential Drug Targets
inferredcites →https://doi.org/10.1126/science.1183670openalex-snapshot
The Genome of the Western Clawed Frog Xenopus tropicalis
inferredcites →https://doi.org/10.1159/000134742openalex-snapshot
Definition of the critical interval for Smith-Magenis syndrome
inferredcites →https://doi.org/10.1172/jci60434openalex-snapshot
Hooked! Modeling human disease in zebrafish
inferredcites →https://doi.org/10.1177/088307380101600610openalex-snapshot
Evidence for Apoptosis in the Fetal Down Syndrome Brain
inferredcites →https://doi.org/10.1186/1471-213x-7-59openalex-snapshot
BDNF promotes target innervation of Xenopus mandibular trigeminal axons in vivo
inferredcites →https://doi.org/10.1186/1471-2199-11-63openalex-snapshot
Functional and cellular characterization of human Retinoic Acid Induced 1 (RAI1) mutations associated with Smith-Magenis Syndrome
inferredcites →https://doi.org/10.1242/dev.001115openalex-snapshot
Controlling morpholino experiments: don't stop making antisense
inferredcites →https://doi.org/10.1242/dev.032912openalex-snapshot
The Wnt antagonists Frzb-1 and Crescent locally regulate basement membrane dissolution in the developing primary mouth
inferredcites →https://doi.org/10.1242/dmm.007666openalex-snapshot
‘Model’ or ‘tool’? New definitions for translational research
inferredcites →https://doi.org/10.1242/dmm.012138openalex-snapshot
Modeling human neurodevelopmental disorders in theXenopustadpole: from mechanisms to therapeutic targets
inferredcites →https://doi.org/10.1371/journal.pbio.0030059openalex-snapshot
Discovery-Based Science Education: Functional Genomic Dissection in Drosophila by Undergraduate Researchers
inferredcites →https://doi.org/10.1371/journal.pone.0078907openalex-snapshot
A Phylogenetic Study of SPBP and RAI1: Evolutionary Conservation of Chromatin Binding Modules
inferredcites →https://doi.org/10.1387/ijdb.052070jlopenalex-snapshot
Developmental expression of Xenopus Fragile X mental retardation-1 gene
inferredcites →https://doi.org/10.1515/revneuro.1997.8.1.13openalex-snapshot
Neurotrophin Regulation of the Developing Nervous System: Analyses of Knockout Mice
inferredcites →https://doi.org/10.1542/peds.2006-0637openalex-snapshot
Brain Developmental Abnormalities in Prader-Willi Syndrome Detected by Diffusion Tensor Imaging
inferredcites →https://doi.org/10.2174/138920210793360952openalex-snapshot
Retinoic Acid Induced 1, RAI1: A Dosage Sensitive Gene Related to Neurobehavioral Alterations Including Autistic Behavior
inferredcites →https://doi.org/10.2174/156802607780487740openalex-snapshot
Morpholino, siRNA, and S-DNA Compared: Impact of Structure and Mechanism of Action on Off-Target Effects and Sequence Specificity
inferredcites →https://doi.org/10.2307/1439568openalex-snapshot
Normal Table of Xenopus Laevis (Daudin)
inferredcites →https://doi.org/10.26028/cybium/1985-92-001openalex-snapshot
Revised procedures for staining and clearing small fishes and other vertebrates for bone and cartilage study
inferredcites →https://doi.org/10.3791/1218openalex-snapshot
Zebrafish Brain Ventricle Injection

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4669820openalex-extracted
Dyrk1a is Required for Craniofacial Development in Xenopus Laevis
inferred← citeshttps://doi.org/10.1002/dvg.23394openalex-snapshot
Using an aquatic model, Xenopus laevis , to uncover the role of chromodomain 1 in craniofacial disorders
inferred← citeshttps://doi.org/10.1007/s40139-017-0128-8openalex-snapshot
Modeling Human Craniofacial Disorders in Xenopus
inferred← citeshttps://doi.org/10.1016/b978-0-323-62520-3.00024-5openalex-snapshot
Obesity, Metabolic Syndrome and Disorders of Energy Balance
inferred← citeshttps://doi.org/10.1016/bs.pmbts.2015.12.002openalex-snapshot
Rare Syndromes and Common Variants of the Brain-Derived Neurotrophic Factor Gene in Human Obesity
inferred← citeshttps://doi.org/10.1016/j.ajhg.2022.11.012openalex-snapshot
Genome-wide analysis of copy-number variation in humans with cleft lip and/or cleft palate identifies COBLL1, RIC1, and ARHGEF38 as clefting genes
inferred← citeshttps://doi.org/10.1016/j.semcdb.2016.01.016openalex-snapshot
Using frogs faces to dissect the mechanisms underlying human orofacial defects
inferred← citeshttps://doi.org/10.1016/j.tig.2023.10.009openalex-snapshot
Strategies for dissecting the complexity of neurodevelopmental disorders
inferred← citeshttps://doi.org/10.1016/j.ydbio.2021.09.004openalex-snapshot
E-liquids and vanillin flavoring disrupts retinoic acid signaling and causes craniofacial defects in Xenopus embryos
inferred← citeshttps://doi.org/10.1016/j.ydbio.2024.04.004openalex-snapshot
Dyrk1a is required for craniofacial development in Xenopus laevis.
inferred← citeshttps://doi.org/10.1038/s41598-023-34452-wopenalex-snapshot
Possible involvement of silent mutations in cancer pathogenesis and evolution
inferred← citeshttps://doi.org/10.1101/118794openalex-snapshot
Comparison of village dog and wolf genomes highlights the pivotal role of the neural crest in dog domestication
inferred← citeshttps://doi.org/10.1155/2016/1243659openalex-snapshot
Secretome of Olfactory Mucosa Mesenchymal Stem Cell, a Multiple Potential Stem Cell
inferred← citeshttps://doi.org/10.1186/s12915-018-0535-2openalex-snapshot
Comparison of village dog and wolf genomes highlights the role of the neural crest in dog domestication
inferred← citeshttps://doi.org/10.1186/s13039-015-0179-7openalex-snapshot
Copy number loss upstream of RAI1 uncovers gene expression regulatory region that may impact Potocki–Lupski syndrome diagnosis
inferred← citeshttps://doi.org/10.1201/9781003050230-20openalex-snapshot
Craniofacial Development and Disorders—Contributions of Xenopus
inferred← citeshttps://doi.org/10.1201/9781003050230-9openalex-snapshot
The Development and Evolution of the Vertebrate Neural Crest
inferred← citeshttps://doi.org/10.1210/jc.2014-4215openalex-snapshot
Whole Exome Sequencing IdentifiesRAI1Mutation in a Morbidly Obese Child Diagnosed With ROHHAD Syndrome
inferred← citeshttps://doi.org/10.1242/jeb.151043openalex-snapshot
Reversible developmental stasis in response to nutrient availability in theXenopus laevisCNS
inferred← citeshttps://doi.org/10.1371/journal.pone.0185729openalex-snapshot
E-cigarette aerosol exposure can cause craniofacial defects in Xenopus laevis embryos and mammalian neural crest cells
inferred← citeshttps://doi.org/10.15252/embj.201696257openalex-snapshot
Reorganization of inter‐chromosomal interactions in the 2q37‐deletion syndrome
inferred← citeshttps://doi.org/10.20944/preprints202407.2052.v1openalex-snapshot
Novel De Novo RAI1:c.2736delC Variant Identified in A Child with Features of Smith-Magenis: Insight from Whole Genomes Joint Analysis
inferred← citeshttps://doi.org/10.2147/tacg.s128455openalex-snapshot
RAI1 gene mutations: mechanisms of Smith–Magenis Syndrome
inferred← citeshttps://doi.org/10.2217/epi-2016-0090openalex-snapshot
Yin–Yang Actions of Histone Methylation Regulatory Complexes in the Brain
inferred← citeshttps://doi.org/10.3389/fcell.2023.1168643openalex-snapshot
Recognition of H2AK119ub plays an important role in RSF1-regulated early Xenopus development
inferred← citeshttps://doi.org/10.3389/fgene.2022.833083openalex-snapshot
16p12.1 Deletion Orthologs are Expressed in Motile Neural Crest Cells and are Important for Regulating Craniofacial Development in Xenopus laevis
inferred← citeshttps://doi.org/10.3389/fmed.2025.1671687openalex-snapshot
The Xenopus model as a tool for investigating craniofacial developmental disorders
inferred← citeshttps://doi.org/10.3389/fphys.2019.00817openalex-snapshot
The Many Faces of Xenopus: Xenopus laevis as a Model System to Study Wolf–Hirschhorn Syndrome
inferred← citeshttps://doi.org/10.3390/biology7020031openalex-snapshot
A Rare De Novo RAI1 Gene Mutation Affecting BDNF-Enhancer-Driven Transcription Activity Associated with Autism and Atypical Smith-Magenis Syndrome Presentation
inferred← citeshttps://doi.org/10.3390/ijms16047627openalex-snapshot
Phenotypic and Molecular Convergence of 2q23.1 Deletion Syndrome with Other Neurodevelopmental Syndromes Associated with Autism Spectrum Disorder
inferred← citeshttps://doi.org/10.3390/ijms26146667openalex-snapshot
Retinoic Acid Induced 1 and Smith–Magenis Syndrome: From Genetics to Biology and Possible Therapeutic Strategies
inferred← citeshttps://doi.org/10.3390/jpm14090901openalex-snapshot
Novel RAI1:c.2736delC Variant in Smith–Magenis Syndrome: Identification by Whole Genome Sequencing and Joint Analysis
inferred← citeshttps://doi.org/10.4236/cc.2025.134004openalex-snapshot
Geometry Optimization, Quantum Chemical Analysis, Visual Study of Weak Interactions, and the Antifungal Activity Studies of Some Metal (II) Complexes of 1,4-Benzodioxane-6-Carbaldehyde Thiosemicarbazone by Molecular Docking
inferred← citeshttps://doi.org/10.5772/intechopen.68174openalex-snapshot
Olfactory Mucosa Mesenchymal Stem Cells and Biomaterials: A New Combination to Regenerative Therapies after Peripheral Nerve Injury
inferred← citeshttps://doi.org/10.64898/2026.06.11.731717openalex-snapshot
RAI1 safeguards fidelity and tempo of human neurodevelopmental gene expression
inferred← citeshttps://doi.org/10.7302/1431openalex-snapshot
Promoter Selection and Smith-Magenis Syndrome Protein Retinoic Acid Induced-1 in Neuronal Activity-Dependent Transcription
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