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α-Linolenic acid attenuates high glucose-induced apoptosis in cultured human umbilical vein endothelial cells via PI3K/Akt/eNOS pathway

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/(sici)1097-4644(19991101)75:2<258::aid-jcb8>3.0.co;2-3openalex-snapshot
Nitric oxide prevents apoptosis of human endothelial cells from high glucose exposure during early stage
inferredcites →https://doi.org/10.1007/s00125-002-1003-6openalex-snapshot
Interaction of glucose and long chain fatty acids (C18) on antioxidant defences and free radical damage in porcine vascular smooth muscle cells in vitro
inferredcites →https://doi.org/10.1007/s00125-004-1600-7openalex-snapshot
Acute effects of monounsaturated fatty acids with and without omega-3 fatty acids on vascular reactivity in individuals with type 2 diabetes
inferredcites →https://doi.org/10.1016/j.bbalip.2004.12.003openalex-snapshot
Substituting dietary linoleic acid with α-linolenic acid improves insulin sensitivity in sucrose fed rats
inferredcites →https://doi.org/10.1016/j.cellsig.2005.05.009openalex-snapshot
High glucose-induced apoptosis in human vascular endothelial cells is mediated through NF-κB and c-Jun NH2-terminal kinase pathway and prevented by PI3K/Akt/eNOS pathway
inferredcites →https://doi.org/10.1016/j.cyto.2004.02.010openalex-snapshot
Acute changes in dietary omega-3 fatty acid intake lowers soluble interleukin-6 receptor in healthy adult normal weight and overweight males
inferredcites →https://doi.org/10.1016/j.nut.2005.05.012openalex-snapshot
Saturated, unsaturated, and trans-fatty acids modulate oxidative burst induced by high dextrose in human umbilical vein endothelial cells
inferredcites →https://doi.org/10.1016/s0021-9150(02)00427-6openalex-snapshot
Dietary α-linolenic acid decreases C-reactive protein, serum amyloid A and interleukin-6 in dyslipidaemic patients
inferredcites →https://doi.org/10.1016/s0140-6736(94)92580-1openalex-snapshot
Mediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart disease
inferredcites →https://doi.org/10.1016/s0899-9007(02)00855-9openalex-snapshot
Long-chain polyunsaturated fatty acids and chemically induced diabetes mellitus
inferredcites →https://doi.org/10.1016/s0952-3278(97)90572-xopenalex-snapshot
Cytotoxic action of alpha-linolenic and eicosapentaenoic acids on myeloma cells in vitro
inferredcites →https://doi.org/10.1038/21218openalex-snapshot
Regulation of endothelium-derived nitric oxide production by the protein kinase Akt
inferredcites →https://doi.org/10.1055/s-0038-1642387openalex-snapshot
Comparison of the Effects of Two Diets Rich in Monounsaturated Fatty Acids Differing in their Linoleic/α-Linolenic Acid Ratio on Platelet Aggregation
inferredcites →https://doi.org/10.1073/pnas.0502903102openalex-snapshot
Docosahexaenoic acid: A positive modulator of Akt signaling in neuronal survival
inferredcites →https://doi.org/10.1074/jbc.m412385200openalex-snapshot
Free Fatty Acids Inhibit Serum Deprivation-induced Apoptosis through GPR120 in a Murine Enteroendocrine Cell Line STC-1
inferredcites →https://doi.org/10.1093/ajcn/69.5.890openalex-snapshot
Dietary intake of α-linolenic acid and risk of fatal ischemic heart disease among women
inferredcites →https://doi.org/10.1093/ajcn/74.5.612openalex-snapshot
Relation between dietary linolenic acid and coronary artery disease in the National Heart, Lung, and Blood Institute Family Heart Study
inferredcites →https://doi.org/10.1161/01.cir.0000014682.14181.f2openalex-snapshot
Early Protection Against Sudden Death by n-3 Polyunsaturated Fatty Acids After Myocardial Infarction
inferredcites →https://doi.org/10.1161/01.cir.0000038493.65177.94openalex-snapshot
Fish Consumption, Fish Oil, Omega-3 Fatty Acids, and Cardiovascular Disease
inferredcites →https://doi.org/10.1161/01.cir.0000124477.91474.ffopenalex-snapshot
A Walnut Diet Improves Endothelial Function in Hypercholesterolemic Subjects
inferredcites →https://doi.org/10.1161/01.cir.0000132503.19410.6bopenalex-snapshot
Accumulated Evidence on Fish Consumption and Coronary Heart Disease Mortality
inferredcites →https://doi.org/10.1161/01.cir.101.22.2618openalex-snapshot
High Glucose–Induced Apoptosis in Human Endothelial Cells Is Mediated by Sequential Activations of c-Jun NH 2 -Terminal Kinase and Caspase-3
inferredcites →https://doi.org/10.1161/01.cir.99.18.2452openalex-snapshot
Prevention of Sudden Cardiac Death by Dietary Pure ω-3 Polyunsaturated Fatty Acids in Dogs
inferredcites →https://doi.org/10.1161/01.res.86.1.24openalex-snapshot
Angiopoietin-1 Regulates Endothelial Cell Survival Through the Phosphatidylinositol 3′-Kinase/Akt Signal Transduction Pathway
inferredcites →https://doi.org/10.1161/01.res.87.6.434openalex-snapshot
Endothelial Cell Apoptosis in Angiogenesis and Vessel Regression
inferredcites →https://doi.org/10.1161/01.res.88.2.e14openalex-snapshot
Mechanisms Underlying Endothelial Dysfunction in Diabetes Mellitus
inferredcites →https://doi.org/10.1161/circulationaha.104.489534openalex-snapshot
Dietary Linolenic Acid Is Inversely Associated With Calcified Atherosclerotic Plaque in the Coronary Arteries
inferredcites →https://doi.org/10.1161/circulationaha.105.572008openalex-snapshot
Dietary α-Linolenic Acid Intake and Risk of Sudden Cardiac Death and Coronary Heart Disease
inferredcites →https://doi.org/10.1194/jlr.m300396-jlr200openalex-snapshot
Dietary α-linolenic acid reduces COX-2 expression and induces apoptosis of hepatoma cells
inferredcites →https://doi.org/10.1194/jlr.m400514-jlr200openalex-snapshot
Compartmental modeling to quantify α-linolenic acid conversion after longer term intake of multiple tracer boluses
inferredcites →https://doi.org/10.2337/diabetes.51.1.159openalex-snapshot
Hyperglycemia-Induced Apoptosis in Human Umbilical Vein Endothelial Cells
inferredcites →https://doi.org/10.2337/diacare.14.12.1160openalex-snapshot
Biological Effects of ω-3 Fatty Acids in Diabetes Mellitus
inferredcites →https://doi.org/10.2337/diacare.27.10.2563openalex-snapshot
Effect of α-Linolenic Acid–Containing Linseed Oil on Coagulation in Type 2 Diabetes

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4633896openalex-extracted
Novel Sulfonyl-Substituted Tetrandrine Derivatives for Colon Cancer Treatment by Inducing Mitochondrial Apoptosis and Inhibiting PI3K/AKT/mTOR Pathway
inferred← citeshttps://doi.org/10.1002/ejlt.201700468openalex-snapshot
Effects of Linoleic and Alpha‐Linolenic Ratios and Concentrations on In Vitro Endothelial Cell Responses
inferred← citeshttps://doi.org/10.1002/mnfr.201400569openalex-snapshot
Dairy nutrients and their effect on inflammatory profile in molecular studies
inferred← citeshttps://doi.org/10.1007/s00726-010-0797-7openalex-snapshot
A role for PPARα in the regulation of arginine metabolism and nitric oxide synthesis
inferred← citeshttps://doi.org/10.1007/s00726-016-2243-yopenalex-snapshot
NO synthesis from arginine is favored by α-linolenic acid in mice fed a high-fat diet
inferred← citeshttps://doi.org/10.1007/s10495-014-0977-0openalex-snapshot
Berberine reduces ischemia/reperfusion-induced myocardial apoptosis via activating AMPK and PI3K–Akt signaling in diabetic rats
inferred← citeshttps://doi.org/10.1007/s10557-010-6277-1openalex-snapshot
AMP-Activated Protein Kinase Inhibits Homocysteine-Induced Dysfunction and Apoptosis in Endothelial Progenitor Cells
inferred← citeshttps://doi.org/10.1007/s12272-001-1164-yopenalex-snapshot
Inhibitory effects of crocetin on high glucose-induced apoptosis in cultured human umbilical vein endothelial cells and its mechanism
inferred← citeshttps://doi.org/10.1016/j.arcmed.2011.04.008openalex-snapshot
α-Linolenic Acid Intake Attenuates Myocardial Ischemia/Reperfusion Injury through Anti-inflammatory and Anti-oxidative Stress Effects in Diabetic But Not Normal Rats
inferred← citeshttps://doi.org/10.1016/j.bbrc.2017.02.011openalex-snapshot
Biphasic effect of alpha-linolenic acid on glucose-induced dysmorphogenesis and lipoperoxidation in whole rat embryo in culture
inferred← citeshttps://doi.org/10.1016/j.bioorg.2023.107069openalex-snapshot
Novel sulfonyl-substituted tetrandrine derivatives for colon cancer treatment by inducing mitochondrial apoptosis and inhibiting PI3K/AKT/mTOR pathway
inferred← citeshttps://doi.org/10.1016/j.biopha.2009.03.002openalex-snapshot
Advanced glycation endproducts increase EPC apoptosis and decrease nitric oxide release via MAPK pathways
inferred← citeshttps://doi.org/10.1016/j.cnd.2018.06.002openalex-snapshot
Importance du métabolisme des protéines et des acides aminés dans la prévention et la prise en charge du syndrome métabolique. Modulation par les acides gras n-3
inferred← citeshttps://doi.org/10.1016/j.ejphar.2009.09.015openalex-snapshot
α-Linolenic acid protects renal cells against palmitic acid lipotoxicity via inhibition of endoplasmic reticulum stress
inferred← citeshttps://doi.org/10.1016/j.etap.2013.11.009openalex-snapshot
Protective effects of timosaponin B-II on high glucose-induced apoptosis in human umbilical vein endothelial cells
inferred← citeshttps://doi.org/10.1016/j.jff.2022.105041openalex-snapshot
α-Linolenic acid induces apoptosis, inhibits the invasion and metastasis, and arrests cell cycle in human breast cancer cells by inhibiting fatty acid synthase
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2015.02.001openalex-snapshot
Mechanisms of enhanced insulin secretion and sensitivity with n-3 unsaturated fatty acids
inferred← citeshttps://doi.org/10.1016/j.phrs.2023.106925openalex-snapshot
Natural products in non-alcoholic fatty liver disease (NAFLD): Novel lead discovery for drug development
inferred← citeshttps://doi.org/10.1016/j.prostaglandins.2023.106704openalex-snapshot
Fatty acids act on vascular endothelial cells and influence the development of cardiovascular disease
inferred← citeshttps://doi.org/10.1039/c6fo00288aopenalex-snapshot
Fucoidan from Undaria pinnatifida prevents vascular dysfunction through PI3K/Akt/eNOS-dependent mechanisms in the l -NAME-induced hypertensive rat model
inferred← citeshttps://doi.org/10.1039/c9ra03268aopenalex-snapshot
Protective effects of macamides from Lepidium meyenii Walp. against corticosterone-induced neurotoxicity in PC12 cells
inferred← citeshttps://doi.org/10.1111/j.1749-6632.2009.04703.xopenalex-snapshot
Effects of Omega‐3 Fatty Acids on Apoptosis of Human Gastric Epithelial Cells Exposed to Silica‐Immobilized Glucose Oxidase
inferred← citeshttps://doi.org/10.1111/j.1749-6632.2009.04887.xopenalex-snapshot
Inhibitory Mechanism of Omega‐3 Fatty Acids in Pancreatic Inflammation and Apoptosis
inferred← citeshttps://doi.org/10.1139/bcb-2019-0403openalex-snapshot
Inhibition of long noncoding RNA MALAT1 suppresses high glucose-induced apoptosis and inflammation in human umbilical vein endothelial cells by suppressing the NF-κB signaling pathway
inferred← citeshttps://doi.org/10.1139/y09-040openalex-snapshot
Rosiglitazone inhibits high glucose-induced apoptosis in human umbilical vein endothelial cells through the PI3K/Akt/eNOS pathway
inferred← citeshttps://doi.org/10.1155/2013/196283openalex-snapshot
Panax Quinquefolius Saponin of Stem and Leaf Attenuates Intermittent High Glucose-Induced Oxidative Stress Injury in Cultured Human Umbilical Vein Endothelial Cells via PI3K/Akt/GSK-3βPathway
inferred← citeshttps://doi.org/10.1155/sci5/6749863openalex-snapshot
Brown Yar Ko Rice Protects Against Hyperglycemia‐Induced Endothelial Injury via Antioxidant and SIRT1 Activation
inferred← citeshttps://doi.org/10.1186/s12944-017-0611-6openalex-snapshot
ALA/LA ameliorates glucose toxicity on HK-2 cells by attenuating oxidative stress and apoptosis through the ROS/p38/TGF-β1 pathway
inferred← citeshttps://doi.org/10.1186/s43014-022-00090-4openalex-snapshot
The exploration and utilization of functional substances in edible insects: a review
inferred← citeshttps://doi.org/10.12659/aot.913800openalex-snapshot
Metabolomic Characterization of Human Model of Liver Rejection Identifies Aberrancies Linked to Cyclooxygenase (COX) and Nitric Oxide Synthase (NOS)
inferred← citeshttps://doi.org/10.1371/journal.pone.0068489openalex-snapshot
Alpha-Linolenic Acid Exerts an Endothelial Protective Effect against High Glucose Injury via PI3K/Akt Pathway
inferred← citeshttps://doi.org/10.1371/journal.pone.0112243openalex-snapshot
Glimepiride Promotes Osteogenic Differentiation in Rat Osteoblasts via the PI3K/Akt/eNOS Pathway in a High Glucose Microenvironment
inferred← citeshttps://doi.org/10.1590/s1726-46342010000300007openalex-snapshot
Toxicidad oral a 60 días del aceite de sacha inchi (Plukenetia volubilis L.) y linaza (Linum usitatissimum L.) y determinación de la dosis letal 50 en roedores
inferred← citeshttps://doi.org/10.3109/13880209.2012.740052openalex-snapshot
Catalpol decreases peroxynitrite formation and consequently exerts cardioprotective effects against ischemia/reperfusion insult
inferred← citeshttps://doi.org/10.3171/jns/2008/109/10/0691openalex-snapshot
Increase in phosphorylation of Akt and its downstream signaling targets and suppression of apoptosis by simvastatin after traumatic brain injury
inferred← citeshttps://doi.org/10.3390/molecules23123372openalex-snapshot
Ethyl Rosmarinate Protects High Glucose-Induced Injury in Human Endothelial Cells
inferred← citeshttps://doi.org/10.3390/nu12092679openalex-snapshot
Dietary α-Linolenic Acid Counters Cardioprotective Dysfunction in Diabetic Mice: Unconventional PUFA Protection
inferred← citeshttps://doi.org/10.3892/mmr.2016.4881openalex-snapshot
Cilostazol suppresses angiotensin II-induced apoptosis in endothelial cells
inferred← citeshttps://doi.org/10.4306/pi.2009.6.2.102openalex-snapshot
AKT1 Gene Polymorphisms and Obstetric Complications in the Patients with Schizophrenia
inferred← citeshttps://doi.org/10.61845/agrimedical.1356667openalex-snapshot
Alfa-Linolenik Asitin Apoptotik Etkileri
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