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Chitosan oligosaccharide: Biological activities and potential therapeutic applications
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inferredcites →https://doi.org/10.1007/bf02977405openalex-snapshotChitosan Oligosaccharide inhibits203HgCl2-induced genotoxicity in mice: Micronuclei occurrence and chromosomal aberration
inferredcites →https://doi.org/10.1007/s00253-007-0898-8openalex-snapshotThe antibacterial and immunostimulative effect of chitosan-oligosaccharides against infection by Staphylococcus aureus isolated from bovine mastitis
inferredcites →https://doi.org/10.1007/s10068-014-0131-3openalex-snapshotThe reduction effect of low molecular weight chitosan oligosaccharide (GO2KA1) on postprandial blood glucose levels in healthy individuals
inferredcites →https://doi.org/10.1007/s10856-012-4747-7openalex-snapshotEffects of molecular weights on the absorption, distribution and urinary excretion of intraperitoneally administrated carboxymethyl chitosan in rats
inferredcites →https://doi.org/10.1007/s11010-009-0284-1openalex-snapshotRETRACTED ARTICLE: Chitosan prevents oxidative stress-induced amyloid β formation and cytotoxicity in NT2 neurons: involvement of transcription factors Nrf2 and NF-κB
inferredcites →https://doi.org/10.1007/s13346-016-0295-xopenalex-snapshotImproved mucoadhesion and cell uptake of chitosan and chitosan oligosaccharide surface-modified polymer nanoparticles for mucosal delivery of proteins
inferredcites →https://doi.org/10.1016/j.actbio.2015.10.017openalex-snapshotPreferential tumor accumulation and desirable interstitial penetration of poly(lactic-co-glycolic acid) nanoparticles with dual coating of chitosan oligosaccharide and polyethylene glycol-poly(d,l-lactic acid)
inferredcites →https://doi.org/10.1016/j.bcp.2015.05.016openalex-snapshotActivation of AMPK by chitosan oligosaccharide in intestinal epithelial cells: Mechanism of action and potential applications in intestinal disorders
inferredcites →https://doi.org/10.1016/j.bmcl.2010.03.105openalex-snapshotChitooligosaccharides protect rat cortical neurons against copper induced damage by attenuating intracellular level of reactive oxygen species
inferredcites →https://doi.org/10.1016/j.carbpol.2016.02.077openalex-snapshotChitosan oligosaccharide suppresses tumor progression in a mouse model of colitis-associated colorectal cancer through AMPK activation and suppression of NF-κB and mTOR signaling
inferredcites →https://doi.org/10.1016/j.ejpb.2011.10.011openalex-snapshotPulmonary delivery of elcatonin using surface-modified liposomes to improve systemic absorption: Polyvinyl alcohol with a hydrophobic anchor and chitosan oligosaccharide as effective surface modifiers
inferredcites →https://doi.org/10.1016/j.fct.2006.07.025openalex-snapshotChitooligosaccharides in combination with interferon-γ increase nitric oxide production via nuclear factor-κB activation in murine RAW264.7 macrophages
inferredcites →https://doi.org/10.1016/j.fm.2008.05.003openalex-snapshotAntimicrobial effects of chitosans and chitooligosaccharides, upon Staphylococcus aureus and Escherichia coli, in food model systems
inferredcites →https://doi.org/10.1016/j.ijpharm.2007.11.029openalex-snapshotAntifungal effect of high- and low-molecular-weight chitosan hydrochloride, carboxymethyl chitosan, chitosan oligosaccharide and N-acetyl-d-glucosamine against Candida albicans, Candida krusei and Candida glabrata
inferredcites →https://doi.org/10.1016/j.intimp.2011.12.027openalex-snapshotAnti-inflammatory effects of low-molecular weight chitosan oligosaccharides in IgE–antigen complex-stimulated RBL-2H3 cells and asthma model mice
inferredcites →https://doi.org/10.1016/j.pharmthera.2015.11.012openalex-snapshotGut microbiome in health and disease: Linking the microbiome–gut–brain axis and environmental factors in the pathogenesis of systemic and neurodegenerative diseases
inferredcites →https://doi.org/10.1016/s0304-3835(00)00551-6openalex-snapshotSynergistic cooperation between water-soluble chitosan oligomers and interferon-γ for induction of nitric oxide synthesis and tumoricidal activity in murine peritoneal macrophages
inferredcites →https://doi.org/10.1016/s0304-3940(02)00066-6openalex-snapshotWater-soluble chitosan inhibits the production of pro-inflammatory cytokine in human astrocytoma cells activated by amyloid β peptide and interleukin-1β
inferredcites →https://doi.org/10.1021/acs.jafc.5b05195openalex-snapshotChitosan Oligosaccharide Reduces Intestinal Inflammation That Involves Calcium-Sensing Receptor (CaSR) Activation in Lipopolysaccharide (LPS)-Challenged Piglets
inferredcites →https://doi.org/10.1021/bc3001276openalex-snapshotDevelopment of Chitosan Oligosaccharide-Modified Gold Nanorods for in Vivo Targeted Delivery and Noninvasive Imaging by NIR Irradiation
inferredcites →https://doi.org/10.1021/bm0703214openalex-snapshotSpecific Interaction between Chitosan and Matrix Metalloprotease 2 Decreases the Invasive Activity of Human Melanoma Cells
inferredcites →https://doi.org/10.1021/bm100158popenalex-snapshotPharmacokinetics and Biodegradation Mechanisms of a Versatile Carboxymethyl Derivative of Chitosan in Rats: In Vivo and In Vitro Evaluation
inferredcites →https://doi.org/10.1021/jf0340557openalex-snapshotAngiotensin I Converting Enzyme (ACE) Inhibitory Activity of Hetero-Chitooligosaccharides Prepared from Partially Different Deacetylated Chitosans
inferredcites →https://doi.org/10.1021/jf100662ropenalex-snapshotChitosan Reduces Gluconeogenesis and Increases Glucose Uptake in Skeletal Muscle in Streptozotocin-Induced Diabetic Rats
inferredcites →https://doi.org/10.1021/jf404026fopenalex-snapshotSynthesis, Characterization, and Antimicrobial Activity of Kojic Acid Grafted Chitosan Oligosaccharide
inferredcites →https://doi.org/10.1021/jm201570sopenalex-snapshotSynthesis and Assessment of Globotriose–Chitosan Conjugate, a Novel Inhibitor of Shiga Toxins Produced by Escherichia coli
inferredcites →https://doi.org/10.1023/a:1023480701270openalex-snapshotInhibiton of polyamine biosynthesis in Acanthamoeba castellanii and 12-O-tetradecanoylphorbol-13-acetate-induced ornithine decarboxylase activity by chitosanoligosaccharide
inferredcites →https://doi.org/10.1038/aps.2011.10openalex-snapshotChitosan oligosaccharides suppress LPS-induced IL-8 expression in human umbilical vein endothelial cells through blockade of p38 and Akt protein kinases
inferredcites →https://doi.org/10.1038/sj.ijo.0802693openalex-snapshotThe effect of the dietary supplement, Chitosan, on body weight: a randomised controlled trial in 250 overweight and obese adults
inferredcites →https://doi.org/10.1038/srep08716openalex-snapshotEnzymatic production of defined chitosan oligomers with a specific pattern of acetylation using a combination of chitin oligosaccharide deacetylases
inferredcites →https://doi.org/10.1039/c4fo00469hopenalex-snapshotThe effects of chitosan oligosaccharide (GO2KA1) supplementation on glucose control in subjects with prediabetes
inferredcites →https://doi.org/10.1080/10717540701202887openalex-snapshotSynthesis, Characterization, and Evaluation of Phosphated Cross-Linked Konjac Glucomannan Hydrogels for Colon-Targeted Drug Delivery
inferredcites →https://doi.org/10.1089/jmf.2011.1882openalex-snapshotChitosan Reduces Plasma Adipocytokines and Lipid Accumulation in Liver and Adipose Tissues and Ameliorates Insulin Resistance in Diabetic Rats
inferredcites →https://doi.org/10.1093/jn/119.8.1100openalex-snapshotInteraction of Bile Acids, Phospholipids, Cholesterol and Triglyceride with Dietary Fibers in the Small Intestine of Rats
inferredcites →https://doi.org/10.1093/jn/134.4.945openalex-snapshotAntitumor Effects of Various Low-Molecular-Weight Chitosans Are Due to Increased Natural Killer Activity of Intestinal Intraepithelial Lymphocytes in Sarcoma 180–Bearing Mice
inferredcites →https://doi.org/10.1111/j.1742-7843.2009.00493.xopenalex-snapshotChitosan Oligosaccharides Inhibit the Expression of Interleukin‐6 in Lipopolysaccharide‐induced Human Umbilical Vein Endothelial Cells Through p38 and ERK1/2 Protein Kinases
inferredcites →https://doi.org/10.1124/mol.51.6.1070openalex-snapshotSubstrate Dependence of Angiotensin I-Converting Enzyme Inhibition: Captopril Displays a Partial Selectivity for Inhibition ofN-Acetyl-Seryl-Aspartyl-Lysyl-Proline Hydrolysis Compared with That of Angiotensin I·
inferredcites →https://doi.org/10.1155/2014/827847openalex-snapshotChitosan Oligosaccharides Attenuate Ocular Inflammation in Rats with Experimental Autoimmune Anterior Uveitis
inferredcites →https://doi.org/10.1186/1472-6882-14-272openalex-snapshotEffect of long-term supplementation of low molecular weight chitosan oligosaccharide (GO2KA1) on fasting blood glucose and HbA1c in db/db mice model and elucidation of mechanism of action
inferredcites →https://doi.org/10.1186/s40659-015-0049-0openalex-snapshotCytotoxicity, nitric oxide and acetylcholinesterase inhibitory activity of three limonoids isolated from Trichilia welwitschii (Meliaceae)
inferredcites →https://doi.org/10.1248/bpb.18.1623openalex-snapshotHypoglycemic and Hypolipidemic Effect of Chitosan in Normal and Neonatal Streptozotocin-Induced Diabetic Mice.
inferredcites →https://doi.org/10.1248/bpb.23.1458openalex-snapshotLow Molecular Weight Chitosan Prevents the Progression of Low Dose Streptozotocin-Induced Slowly Progressive Diabetes Mellitus in Mice.
inferredcites →https://doi.org/10.1248/bpb.26.1100openalex-snapshotAntidiabetic Effects of Chitosan Oligosaccharides in Neonatal Streptozotocin-Induced Noninsulin-Dependent Diabetes Mellitus in Rats
inferredcites →https://doi.org/10.1371/journal.pone.0034969openalex-snapshotAssessment of Chitosan-Affected Metabolic Response by Peroxisome Proliferator-Activated Receptor Bioluminescent Imaging-Guided Transcriptomic Analysis
inferredcites →https://doi.org/10.1371/journal.pone.0149820openalex-snapshotPrawn Shell Chitosan Exhibits Anti-Obesogenic Potential through Alterations to Appetite, Affecting Feeding Behaviour and Satiety Signals In Vivo
inferredcites →https://doi.org/10.2133/dmpk.19.76openalex-snapshotProapoptotic Effect of a Dietary Supplement: Water Soluble Chitosan Activates Caspase-8 and Modulating Death Receptor Expression
inferredcites →https://doi.org/10.2147/ijn.s51679openalex-snapshotSilver nanoparticle/chitosan oligosaccharide/poly(vinyl alcohol) nanofibers as wound dressings: a preclinical study
inferredcites →https://doi.org/10.2478/folmed-2013-0002openalex-snapshotAdipose Tissue Hormones and Appetite and Body Weight Regulators an Insulin Resistance / Гормоны Жировой Ткани И Регуляторы Аппетита И Массы Тела При Инсулиновой Резистентности
inferredcites →https://doi.org/10.3109/03639045.2014.935390openalex-snapshotCo-delivery of paclitaxel andα-tocopherol succinate by novel chitosan-based polymeric micelles for improving micellar stability and efficacious combination therapy
inferredcites →https://doi.org/10.3390/ijms12010266openalex-snapshotEffects of the Molecular Weight and the Degree of Deacetylation of Chitosan Oligosaccharides on Antitumor Activity
inferredcites →https://doi.org/10.3390/ijms140815755openalex-snapshotGalactosylated Chitosan Oligosaccharide Nanoparticles for Hepatocellular Carcinoma Cell-Targeted Delivery of Adenosine Triphosphate
inferredcites →https://doi.org/10.3390/md13127067openalex-snapshotLong-Term Feeding of Chitosan Ameliorates Glucose and Lipid Metabolism in a High-Fructose-Diet-Impaired Rat Model of Glucose Tolerance
inferredcites →https://doi.org/10.3892/ol.2014.2115openalex-snapshotDownregulation of CD147 by chitooligosaccharide inhibits MMP-2 expression and suppresses the metastatic potential of human gastric cancer
inferredcites →https://doi.org/10.3892/or.2014.3463openalex-snapshotChitooligosaccharides inhibit ethanol-induced oxidative stress via activation of Nrf2 and reduction of MAPK phosphorylation
inferredcites →https://doi.org/10.5625/lar.2012.28.1.31openalex-snapshotModulation of lipid metabolism by mixtures of protamine and chitooligosaccharide through pancreatic lipase inhibitory activity in a rat model
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4479739openalex-extractedTranscriptome Analysis of the Some Genes of Staphylococcus Aureus Exposed to Alkylated, Nano- and Ordinary Chitosans
inferred← citeshttps://doi.org/10.1002/adbi.202101301openalex-snapshotRecent Advances in the Discovery of Therapeutics to Curtail Islet Amyloid Polypeptide Aggregation for Type 2 Diabetes Treatment
inferred← citeshttps://doi.org/10.1002/cbdv.202502777openalex-snapshotMarine‐Derived Chitosan Oligosaccharides and Their Derivatives: A New Hope for Alzheimer's Prevention and Treatment – A Critical Review
inferred← citeshttps://doi.org/10.1002/chem.201803905openalex-snapshotOxazoline or Oxazolinium Ion? The Protonation State and Conformation of the Reaction Intermediate of Chitinase Enzymes Revisited
inferred← citeshttps://doi.org/10.1002/fsn3.3112openalex-snapshotLow‐molecular weight oligosaccharides from gum tragacanth (Astragalus gossypinus) ameliorate nonalcoholic fatty liver disease ( NAFLD ) in Wistar male rats
inferred← citeshttps://doi.org/10.1002/jper.19-0273openalex-snapshotSulfonated chitosan oligosaccharide alleviates the inhibitory effect of basic fibroblast growth factor on osteogenic differentiation of human periodontal ligament stem cells
inferred← citeshttps://doi.org/10.1002/jsfa.11492openalex-snapshotPreparation, investigation and storage application of thymol–chitooligosaccharide complex with enhanced antioxidant and antibacterial properties
inferred← citeshttps://doi.org/10.1002/jsfa.12125openalex-snapshotEffects of ε‐polylysine and chitooligosaccharide Maillard reaction products on quality of refrigerated sea bass fillets
inferred← citeshttps://doi.org/10.1007/s00289-022-04650-zopenalex-snapshotPreparation of cationic chitooligosaccharide derivatives bearing N-halogenated benzyl pyridinium and assessment of their antimicrobial activities
inferred← citeshttps://doi.org/10.1007/s10499-022-01010-6openalex-snapshotOptimization of the enzymatic hydrolysis process of shrimp viscera (Macrobrachium rosenbergii) with two commercial enzymes, aiming to produce an alternative protein source for aquaculture feed formulation
inferred← citeshttps://doi.org/10.1007/s10499-024-01555-8openalex-snapshotBiodistribution of chitosan oligosaccharide labeled with fluorescein isothiocyanate in the sea cucumber, Apostichopus japonicus (Selenka, 1867)
inferred← citeshttps://doi.org/10.1007/s11095-017-2225-0openalex-snapshotChitooligosaccharides Modified Reduction-Sensitive Liposomes: Enhanced Cytoplasmic Drug Delivery and Osteosarcomas-Tumor Inhibition in Animal Models
inferred← citeshttps://doi.org/10.1007/s11802-022-5088-xopenalex-snapshotEvaluation of Chito-Oligosaccharide (COS) in Vitro and in Vivo: Permeability Characterization in Caco-2 Cells Monolayer and Pharmacokinetics Properties in Rats
inferred← citeshttps://doi.org/10.1007/s11802-024-5842-3openalex-snapshotThe ceRNA Network Indicates Its Immune Function in Peripheral Blood Leukocytes of Half-Smooth Tongue Sole (Cynoglossus semilaevis) After Stimulation with Chitosan Oligosaccharide
inferred← citeshttps://doi.org/10.1007/s12010-024-04876-9openalex-snapshotRecent Progress in Enzymatic Preparation of Chitooligosaccharides with a Single Degree of Polymerization and Their Potential Applications in the Food Sector
inferred← citeshttps://doi.org/10.1007/s13346-020-00824-2openalex-snapshotModulating chitosan-PLGA nanoparticle properties to design a co-delivery platform for glioblastoma therapy intended for nose-to-brain route
inferred← citeshttps://doi.org/10.1007/s40858-026-00801-zopenalex-snapshotEvaluation of chitosan oligosaccharide as an alternative treatment to mitigate Fusarium graminearum and mycotoxin contamination in wheat
inferred← citeshttps://doi.org/10.1007/s43450-026-00766-9openalex-snapshotHarnessing Natural Products as AMPK Activators: A Promising Therapeutic Avenue for Metabolic Dysfunction-Associated Steatotic Liver Disease
inferred← citeshttps://doi.org/10.1016/j.ajps.2022.02.003openalex-snapshotAlantolactone-loaded chitosan/hyaluronic acid nanoparticles suppress psoriasis by deactivating STAT3 pathway and restricting immune cell recruitment
inferred← citeshttps://doi.org/10.1016/j.anifeedsci.2025.116518openalex-snapshotChitosan oligosaccharides reduced abdominal fat deposition by regulating hepatic lipid metabolism, anti-oxidant capacity and inflammatory response in frizzled chicken
inferred← citeshttps://doi.org/10.1016/j.apmt.2022.101581openalex-snapshotAn injectable, self-healing, 3D printable, double network co-enzymatically crosslinked hydrogel using marine poly- and oligo-saccharides for wound healing application
inferred← citeshttps://doi.org/10.1016/j.apmt.2023.101884openalex-snapshotLDH-doped gelatin-chitosan scaffold with aligned microchannels improves anti-inflammation and neuronal regeneration with guided axonal growth for effectively recovering spinal cord injury
inferred← citeshttps://doi.org/10.1016/j.apmt.2024.102340openalex-snapshotEuropium-based complex crosslinked with hyaluronic acid sponge with controllable adaptive capability to promote effective scarless regeneration of burn wound
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2021.121131openalex-snapshotChitosan hydrogel/3D-printed poly(ε‐caprolactone) hybrid scaffold containing synovial mesenchymal stem cells for cartilage regeneration based on tetrahedral framework nucleic acid recruitment
inferred← citeshttps://doi.org/10.1016/j.biopha.2018.03.108openalex-snapshotChitooligosaccharide: An evaluation of physicochemical and biological properties with the proposition for determination of thermal degradation products
inferred← citeshttps://doi.org/10.1016/j.bpc.2024.107236openalex-snapshotInhibition of insulin fibrillation by carboxyphenylboronic acid-modified chitosan oligosaccharide based on electrostatic interactions and hydrophobic interactions
inferred← citeshttps://doi.org/10.1016/j.carbpol.2018.10.067openalex-snapshotInfluence of chitosan oligosaccharide on the gelling and wound healing properties of injectable hydrogels based on carboxymethyl chitosan/alginate polyelectrolyte complexes
inferred← citeshttps://doi.org/10.1016/j.carbpol.2023.121180openalex-snapshotModulation of tryptophan metabolism via AHR-IL22 pathway mediates the alleviation of DSS-induced colitis by chitooligosaccharides with different degrees of polymerization
inferred← citeshttps://doi.org/10.1016/j.carbpol.2023.121772openalex-snapshotStaphylococcus aureus enters viable-but-nonculturable state in response to chitooligosaccharide stress by altering metabolic pattern and transmembrane transport function
inferred← citeshttps://doi.org/10.1016/j.carbpol.2026.125356openalex-snapshotChito-oligosaccharide-reinforced thermally cross-linked fish skin gelatin films with silver nanoparticles: Enhanced properties and accelerated wound healing
inferred← citeshttps://doi.org/10.1016/j.carpta.2025.101076openalex-snapshotChitooligosaccharides promote intestinal adhesion of Clostridium butyricum and enhance gut health, immunity, and antioxidant capacity in largemouth bass
inferred← citeshttps://doi.org/10.1016/j.carres.2020.108046openalex-snapshotIdentification of low molecular weight degradation products from chitin and chitosan by electrospray ionization time-of-flight mass spectrometry
inferred← citeshttps://doi.org/10.1016/j.cbi.2019.03.027openalex-snapshotChitosan oligosaccharides prevent doxorubicin-induced oxidative stress and cardiac apoptosis through activating p38 and JNK MAPK mediated Nrf2/ARE pathway
inferred← citeshttps://doi.org/10.1016/j.cbi.2024.111316openalex-snapshotChitooligosaccharide-epigallocatechin gallate conjugate ameliorates lipid accumulation and promotes browning of white adipose tissue in high fat diet fed rats
inferred← citeshttps://doi.org/10.1016/j.cbi.2025.111680openalex-snapshotChitosan oligosaccharide improves diabetic nephropathy by attenuating renal fibrogenesis and strengthening intestinal barriers in type 2 diabetic rats
inferred← citeshttps://doi.org/10.1016/j.cej.2022.139445openalex-snapshotDual-targeting celecoxib nanoparticles protect intestinal epithelium and regulate macrophage polarization for ulcerative colitis treatment
inferred← citeshttps://doi.org/10.1016/j.cej.2025.164449openalex-snapshotSustainable conversion of liquefied-chitin to anti-bacterial and photothermal polyurethane foams for efficient desalination of seawater
inferred← citeshttps://doi.org/10.1016/j.colsurfa.2022.128423openalex-snapshotDevelopment of cytidine 5′-monophosphate-protected gold-nanoclusters to be a direct luminescent substrate via aggregation-induced emission enhancement for ratiometric determination of alkaline phosphatase and inhibitor evaluation
inferred← citeshttps://doi.org/10.1016/j.dyepig.2018.07.004openalex-snapshotPreparation and antifungal properties of monosubstituted zinc(П) phthalocyanine-chitosan oligosaccharide conjugates and their quaternized derivatives
inferred← citeshttps://doi.org/10.1016/j.ejps.2019.01.031openalex-snapshotSurfactant-free solid dispersion of BCS class IV drug in an amorphous chitosan oligosaccharide matrix for concomitant dissolution in vitro - permeability increase
inferred← citeshttps://doi.org/10.1016/j.eurpolymj.2021.110507openalex-snapshotOptimization enzymatic degradation of chitosan into amphiphilic chitooligosaccharides for application in mitigating liver steatosis and cholesterol regulation
inferred← citeshttps://doi.org/10.1016/j.fbio.2023.102963openalex-snapshotEnhancement of antioxidant activities and stabilities of quercetin and isoquercetin through the combination of nanoencapsulation and hydrogel incorporation
inferred← citeshttps://doi.org/10.1016/j.foodhyd.2026.113179openalex-snapshotSimultaneous coupling of Maillard reaction and heat-induced aggregation: a strategy for regulating the structural evolution of soybean protein isolate - chitosan oligosaccharide conjugated nanogels
inferred← citeshttps://doi.org/10.1016/j.foodres.2019.108974openalex-snapshotDesalted duck egg white peptides-chitosan oligosaccharide copolymers as calcium delivery systems: Preparation, characterization and calcium release evaluation in vitro and vivo
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2020.09.156openalex-snapshotEDTA-functionalized magnetic chitosan oligosaccharide and carboxymethyl cellulose nanocomposite: Synthesis, characterization, and Pb(II) adsorption performance
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