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Cucurbitacin B interacts synergistically with antibiotics against Staphylococcus aureus clinical isolates and exhibits antiviral activity against HSV-1

https://doi.org/10.1016/j.sajb.2016.10.001
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/ardp.201500019openalex-snapshot
Plant‐Derived Urease Inhibitors as Alternative Chemotherapeutic Agents
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Plumbagin, a Plant-Derived Compound, Exhibits Antifungal Combinatory Effect with Amphotericin B againstCandida albicansClinical Isolates and Anti-hepatitis C Virus Activity
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Persistent herpes simplex virus infection and mechanisms of virus drug resistance
inferredcites →https://doi.org/10.1007/s00405-008-0625-9openalex-snapshot
Inhibitory effects of cucurbitacin B on laryngeal squamous cell carcinoma
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Cytotoxic Effect of Freeze-Dried Extract of Ecballium elaterium Fruit on Gastric Adenocarcinoma (AGS) and Esophageal Squamous Cell Carcinoma (KYSE30) Cell Lines
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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
inferredcites →https://doi.org/10.1016/0378-1135(93)90141-sopenalex-snapshot
Virology. A laboratory manual
inferredcites →https://doi.org/10.1016/j.fitote.2005.02.007openalex-snapshot
Immunomodulatory activity of cucurbitacin E isolated from Ecballium elaterium
inferredcites →https://doi.org/10.1016/j.fitote.2010.11.016openalex-snapshot
Synergy research: Approaching a new generation of phytopharmaceuticals
inferredcites →https://doi.org/10.1016/j.ijantimicag.2007.07.011openalex-snapshot
Reduced glycopeptide susceptibility in methicillin-resistant Staphylococcus aureus (MRSA)
inferredcites →https://doi.org/10.1016/j.ijantimicag.2013.04.023openalex-snapshot
Management of herpesvirus infections
inferredcites →https://doi.org/10.1016/j.ijantimicag.2013.11.005openalex-snapshot
Activity of ceftobiprole against methicillin-resistant Staphylococcus aureus strains with reduced susceptibility to daptomycin, linezolid or vancomycin, and strains with defined SCCmec types
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Antimicrobial activity of southern African medicinal plants with dermatological relevance: From an ethnopharmacological screening approach, to combination studies and the isolation of a bioactive compound
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Anti-Herpes Simplex Virus Activity of Moronic Acid Purified from Rhus javanica In Vitro and In Vivo
inferredcites →https://doi.org/10.1016/s0166-3542(99)00037-6openalex-snapshot
Antiviral effects of 28-deacetylsendanin on herpes simplex virus-1 replication
inferredcites →https://doi.org/10.1016/s2221-1691(11)60100-7openalex-snapshot
Effect of ethanolic extract of Ecballium elaterium against Staphylococcus aureus and Candida albicans
inferredcites →https://doi.org/10.1038/nri2937openalex-snapshot
Recognition of herpesviruses by the innate immune system
inferredcites →https://doi.org/10.1039/b418841copenalex-snapshot
Cucurbitacins and cucurbitane glycosides: structures and biological activities
inferredcites →https://doi.org/10.1039/p19740002552openalex-snapshot
The constituents of Ecballium elaterium L. Part XXIII. Cucurbitacins and hexanorcucurbitacins
inferredcites →https://doi.org/10.1055/s-0030-1250736openalex-snapshot
Plant-Based Antimicrobial Studies – Methods and Approaches to Study the Interaction between Natural Products
inferredcites →https://doi.org/10.1055/s-2008-1074518openalex-snapshot
Phytochemicals for Bacterial Resistance - Strengths, Weaknesses and Opportunities
inferredcites →https://doi.org/10.1080/09674845.2004.11732646openalex-snapshot
Antibacterial activity of a new, stable, aqueous extract of allicin against methicillin-resistant Staphylococcus aureus
inferredcites →https://doi.org/10.1081/clt-100100936openalex-snapshot
Ecbalium elaterium(Squirting Cucumber)—Remedy or Poison?
inferredcites →https://doi.org/10.1093/jac/dkh136openalex-snapshot
Putranjivain A from Euphorbia jolkini inhibits both virus entry and late stage replication of herpes simplex virus type 2 in vitro
inferredcites →https://doi.org/10.1097/cad.0b013e3283541384openalex-snapshot
Biological activities and potential molecular targets of cucurbitacins
inferredcites →https://doi.org/10.1111/j.1472-765x.2010.02870.xopenalex-snapshot
In vitro antiherpes effects of a C-glycosylflavonoid-enriched fraction of Cecropia glaziovii Sneth*
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Penicillin Binding Proteins: key players in bacterial cell cycle and drug resistance processes
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Bioactive natural products with anti-herpes simplex virus properties
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Resistance of Herpes Simplex Viruses to Nucleoside Analogues: Mechanisms, Prevalence, and Management
inferredcites →https://doi.org/10.1128/cmr.00056-05openalex-snapshot
Peptide Antimicrobial Agents
inferredcites →https://doi.org/10.1128/cmr.12.4.564openalex-snapshot
Plant Products as Antimicrobial Agents
inferredcites →https://doi.org/10.1128/cmr.5.4.387openalex-snapshot
Bacterial resistance to tetracycline: mechanisms, transfer, and clinical significance
inferredcites →https://doi.org/10.1158/1940-6207.capr-14-0286openalex-snapshot
Cucurbitacin B Alters the Expression of Tumor-Related Genes by Epigenetic Modifications in NSCLC and Inhibits NNK-Induced Lung Tumorigenesis
inferredcites →https://doi.org/10.18632/oncotarget.1743openalex-snapshot
Inhibition of HER2-integrin signaling by Cucurbitacin B leads to in vitro and in vivo breast tumor growth suppression
inferredcites →https://doi.org/10.2174/1381612811319310002openalex-snapshot
Commercial Aspects of Pharmaceutical Protein Production in Plants
inferredcites →https://doi.org/10.2174/1871520614666140601220915openalex-snapshot
Cucurbitacin B Induces DNA Damage, G2/M Phase Arrest, and Apoptosis Mediated by Reactive Oxygen Species (ROS) in Leukemia K562 Cells
inferredcites →https://doi.org/10.22037/ijpr.2010.825openalex-snapshot
Activity of Some Plant Extracts Against Multi-Drug Resistant Human Pathogens
inferredcites →https://doi.org/10.3109/13880209309082930openalex-snapshot
Toxicity and Partial Characterization of Ecballium elaterium Fruit Juice
inferredcites →https://doi.org/10.4103/2141-9248.144883openalex-snapshot
Antimicrobial synergic effect of allicin and silver nanoparticles on skin infection caused by methicillin-resistant staphylococcus aureus spp
inferredcites →https://doi.org/10.5301/ijao.5000334openalex-snapshot
Role and Antimicrobial Resistance of Staphylococci Involved in Prosthetic Joint Infections
inferredcites →https://doi.org/10.5897/jmpr.9001277openalex-snapshot
Use of bioactive plant products in combination with standard antibiotics: Implications in antimicrobial chemotherapy

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Computational insights into the binding interactions of natural compounds with Varroa destructor targets
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Plausible mechanisms explaining the role of cucurbitacins as potential therapeutic drugs against coronavirus 2019
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Quantification of Cucurbitacin C in Bitter Cucumber and its Reduction by Fermentation and Acidification
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Cucurbitacins: Bioactivities and synergistic effect with small-molecule drugs
inferred← citeshttps://doi.org/10.1016/j.phrs.2022.106587openalex-snapshot
Cucurbitacin B: A review of its pharmacology, toxicity, and pharmacokinetics
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Ethnomedicines of Indian origin for combating COVID-19 infection by hampering the viral replication: using structure-based drug discovery approach
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Quantification of cucurbitacins B and E in Coccinia grandis fruit ethanolic extract and their anti-inflammatory effects in SARS-CoV-2 protein-stimulated macrophages
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AVPCD: a plant-derived medicine database of antiviral phytochemicals for cancer, Covid-19, malaria and HIV
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Establishment and application of highly efficient regeneration, genetic transformation and genome editing system for cucurbitacins biosynthesis in Hemsleya chinensis
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Site-directed mutagenesis identified the key active site residues of 2,3-oxidosqualene cyclase HcOSC6 responsible for cucurbitacins biosynthesis in Hemsleya chinensis
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Additional file 1 of nCoV-19 therapeutics using cucurbitacin I structural derivatives: an in silico approach
inferred← citeshttps://doi.org/10.6084/m9.figshare.26702134openalex-snapshot
Additional file 2 of nCoV-19 therapeutics using cucurbitacin I structural derivatives: an in silico approach
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