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Caveolae compartmentalise β2-adrenoceptor signals by curtailing cAMP production and maintaining phosphatase activity in the sarcoplasmic reticulum of the adult ventricular myocyte

https://doi.org/10.1016/j.yjmcc.2011.06.014

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1 of the 74 references listed on this page is in the Retraction Watch database as retracted (export 2026-10-28): 10.1073/pnas.262787199 (notice 2022-04-26).

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Outgoing claims: the papers this work cites, builds on, or argues with.

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Translation of Ser16 and Thr17 phosphorylation of phospholamban into Ca2+-pump stimulation

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Receptor Number and Caveolar Co-localization Determine Receptor Coupling Efficiency to Adenylyl Cyclase

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G-protein-coupled Receptor Signaling Components Localize in Both Sarcolemmal and Intracellular Caveolin-3-associated Microdomains in Adult Cardiac Myocytes

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inferred← citeshttps://doi.org/10.1152/ajpheart.00068.2015openalex-snapshot

Culture and adenoviral infection of sinoatrial node myocytes from adult mice

inferred← citeshttps://doi.org/10.1152/ajpheart.00081.2014openalex-snapshot

Sarcolemmal cholesterol and caveolin-3 dependence of cardiac function, ischemic tolerance, and opioidergic cardioprotection

inferred← citeshttps://doi.org/10.1152/ajpheart.00209.2018openalex-snapshot

Caveolin-3 KO disrupts t-tubule structure and decreases t-tubularICadensity in mouse ventricular myocytes

inferred← citeshttps://doi.org/10.1152/ajpheart.00458.2017openalex-snapshot

Loss of caveolin-3-dependent regulation ofICain rat ventricular myocytes in heart failure

inferred← citeshttps://doi.org/10.1161/circresaha.110.231340openalex-snapshot

Compartmentalization of β-Adrenergic Signals in Cardiomyocytes

inferred← citeshttps://doi.org/10.1161/circresaha.111.300445openalex-snapshot

Super-resolution Scanning Patch Clamp Reveals Clustering of Functional Ion Channels in Adult Ventricular Myocyte

inferred← citeshttps://doi.org/10.1161/circresaha.116.308964openalex-snapshot

Genetically Encoded Biosensors Reveal PKA Hyperphosphorylation on the Myofilaments in Rabbit Heart Failure

inferred← citeshttps://doi.org/10.1161/circresaha.117.310183openalex-snapshot

PI3K and Calcium Signaling in Cardiovascular Disease

inferred← citeshttps://doi.org/10.1161/circresaha.117.310520openalex-snapshot

Adrenergic Receptors in Individual Ventricular Myocytes

inferred← citeshttps://doi.org/10.1161/circresaha.118.314322openalex-snapshot

β 2 -Adrenergic Stimulation Compartmentalizes β 1 Signaling Into Nanoscale Local Domains by Targeting the C-Terminus of β 1 -Adrenoceptors

inferred← citeshttps://doi.org/10.1161/circresaha.123.322508openalex-snapshot

Functional LTCC-β 2 AR Complex Needs Caveolin-3 and Is Disrupted in Heart Failure

inferred← citeshttps://doi.org/10.1161/circresaha.123.323174openalex-snapshot

Microtubule-Mediated Regulation of β 2 AR Translation and Function in Failing Hearts

inferred← citeshttps://doi.org/10.1177/1535370214560969openalex-snapshot

PDE2 activity differs in right and left rat ventricular myocardium and differentially regulates β 2 adrenoceptor-mediated effects

inferred← citeshttps://doi.org/10.1371/journal.pcbi.1005005openalex-snapshot

A Computational Modeling and Simulation Approach to Investigate Mechanisms of Subcellular cAMP Compartmentation

inferred← citeshttps://doi.org/10.1371/journal.pone.0106905openalex-snapshot

Caveolin Contributes to the Modulation of Basal and β-Adrenoceptor Stimulated Function of the Adult Rat Ventricular Myocyte by Simvastatin: A Novel Pleiotropic Effect

inferred← citeshttps://doi.org/10.14814/phy2.13500openalex-snapshot

Cholesterol depletion does not alter the capacitance or Ca handling of the surface or t‐tubule membranes in mouse ventricular myocytes

inferred← citeshttps://doi.org/10.14814/phy2.15015openalex-snapshot

Mitochondrial A‐kinase anchoring proteins in cardiac ventricular myocytes

inferred← citeshttps://doi.org/10.3389/fphar.2015.00148openalex-snapshot

Studying GPCR/cAMP pharmacology from the perspective of cellular structure

inferred← citeshttps://doi.org/10.3389/fphar.2017.00203openalex-snapshot

Simvastatin Promotes Cardiac Myocyte Relaxation in Association with Phosphorylation of Troponin I

inferred← citeshttps://doi.org/10.3389/fphar.2018.00332openalex-snapshot

Compartmentalized cAMP Signaling Associated With Lipid Raft and Non-raft Membrane Domains in Adult Ventricular Myocytes

inferred← citeshttps://doi.org/10.3389/fphys.2012.00393openalex-snapshot

Caveolins: targeting pro-survival signaling in the heart and brain

inferred← citeshttps://doi.org/10.3389/fphys.2018.01302openalex-snapshot

Partial Mechanical Unloading of the Heart Disrupts L-Type Calcium Channel and Beta-Adrenoceptor Signaling Microdomains

inferred← citeshttps://doi.org/10.3389/fphys.2018.01686openalex-snapshot

Functional Microdomains in Heart’s Pacemaker: A Step Beyond Classical Electrophysiology and Remodeling

inferred← citeshttps://doi.org/10.3390/cells10092456openalex-snapshot

Electrophysiological Remodeling: Cardiac T-Tubules and ß-Adrenoceptors

inferred← citeshttps://doi.org/10.3390/ijms23042145openalex-snapshot

Phosphodiesterases and Compartmentation of cAMP and cGMP Signaling in Regulation of Cardiac Contractility in Normal and Failing Hearts

inferred← citeshttps://doi.org/10.4995/thesis/10251/153143openalex-snapshot

In silico study of calcium handling in the human failing heart

inferred← citeshttps://doi.org/10.70675/19ee12d6z21e8z440fza3cfz9b22674b5d02openalex-snapshot

Thérapie génique de l'insuffisance cardiaque par les phosphodiestérases

inferred← citeshttps://doi.org/10.70675/fbdfc368z779dz4242z9e3az011ad0549f81openalex-snapshot

Physiopathologie de la dysfonction bêta-adrénergique et rôle de la protéine MRP4 au cours du vieillissement, du diabète et du syndrome métabolique

inferred← citeshttps://doi.org/10.7554/elife.52221openalex-snapshot

β3-Adrenoceptor redistribution impairs NO/cGMP/PDE2 signalling in failing cardiomyocytes

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