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Enabling High Structural Specificity to Lipidomics by Coupling Photochemical Derivatization with Tandem Mass Spectrometry

https://doi.org/10.1021/acs.accounts.1c00419
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/anie.201102634openalex-snapshot
Simple Determination of Double‐Bond Positions in Long‐Chain Olefins by Cross‐Metathesis
inferredcites →https://doi.org/10.1002/anie.201310699openalex-snapshot
Pinpointing Double Bonds in Lipids by Paternò‐Büchi Reactions and Mass Spectrometry
inferredcites →https://doi.org/10.1002/anie.201806635openalex-snapshot
An On‐Tissue Paternò–Büchi Reaction for Localization of Carbon–Carbon Double Bonds in Phospholipids and Glycolipids by Matrix‐Assisted Laser‐Desorption–Ionization Mass‐Spectrometry Imaging
inferredcites →https://doi.org/10.1002/anie.201911070openalex-snapshot
On‐Demand Electrochemical Epoxidation in Nano‐Electrospray Ionization Mass Spectrometry to Locate Carbon–Carbon Double Bonds
inferredcites →https://doi.org/10.1002/anie.202016734openalex-snapshot
Imaging and Analysis of Isomeric Unsaturated Lipids through Online Photochemical Derivatization of Carbon–Carbon Double Bonds**
inferredcites →https://doi.org/10.1002/mas.1280060403openalex-snapshot
Mass spectrometry methods for structural determination and analysis of fatty acids
inferredcites →https://doi.org/10.1002/rcm.6503openalex-snapshot
Rapid differentiation of isomeric lipids by photodissociation mass spectrometry of fatty acid derivatives
inferredcites →https://doi.org/10.1016/0009-3084(76)90025-6openalex-snapshot
Fatty acids, part 5: A study of the oxymercuration-demercuration reaction of some C11-unsaturated fatty esters and methyl octadec-cis-10-en-5-ynoate
inferredcites →https://doi.org/10.1016/0009-3084(78)90045-2openalex-snapshot
Location of double bonds and cyclopropane rings in fatty acids by mass spectrometry
inferredcites →https://doi.org/10.1016/j.aca.2018.04.046openalex-snapshot
Benzophenone used as the photochemical reagent for pinpointing C=C locations in unsaturated lipids through shotgun and liquid chromatography-mass spectrometry approaches
inferredcites →https://doi.org/10.1016/s0163-7827(97)00008-8openalex-snapshot
The role of sphingolipids in the process of signal transduction
inferredcites →https://doi.org/10.1016/s1044-0305(00)00172-0openalex-snapshot
Characterization of phosphatidylinositol, phosphatidylinositol-4-phosphate, and phosphatidylinositol-4,5-bisphosphate by electrospray ionization tandem mass spectrometry: A mechanistic study
inferredcites →https://doi.org/10.1016/s1044-0305(03)00064-3openalex-snapshot
Electrospray ionization/tandem quadrupole mass spectrometric studies on phosphatidylcholines: The fragmentation processes
inferredcites →https://doi.org/10.1016/s1044-0305(99)00035-5openalex-snapshot
Structural characterization of triacylglycerols as lithiated adducts by electrospray ionization mass spectrometry using low-energy collisionally activated dissociation on a triple stage quadrupole instrument
inferredcites →https://doi.org/10.1021/ac00263a022openalex-snapshot
Determination of double bond position in monounsaturated fatty acids by mass-analyzed ion-kinetic-energy spectrometry/collision-induced dissociation after chemical ionization of their amino alcohol derivatives
inferredcites →https://doi.org/10.1021/ac0702185openalex-snapshot
Elucidation of Double Bond Position in Unsaturated Lipids by Ozone Electrospray Ionization Mass Spectrometry
inferredcites →https://doi.org/10.1021/ac301652aopenalex-snapshot
Differentiation of Complex Lipid Isomers by Radical-Directed Dissociation Mass Spectrometry
inferredcites →https://doi.org/10.1021/ac403796nopenalex-snapshot
193 nm Ultraviolet Photodissociation Mass Spectrometry for the Structural Elucidation of Lipid A Compounds in Complex Mixtures
inferredcites →https://doi.org/10.1021/ac7017684openalex-snapshot
Ozone-Induced Dissociation: Elucidation of Double Bond Position within Mass-Selected Lipid Ions
inferredcites →https://doi.org/10.1021/acs.analchem.0c00690openalex-snapshot
Enhanced Phospholipid Isomer Analysis by Online Photochemical Derivatization and RPLC-MS
inferredcites →https://doi.org/10.1021/acs.analchem.0c02147openalex-snapshot
Single-Cell Mass Spectrometry Analysis of Metabolites Facilitated by Cell Electro-Migration and Electroporation
inferredcites →https://doi.org/10.1021/acs.analchem.0c02896openalex-snapshot
Next-Generation Paterno–Buchi Reagents for Lipid Analysis by Mass Spectrometry
inferredcites →https://doi.org/10.1021/acs.analchem.0c03150openalex-snapshot
Multifunctional Reactive MALDI Matrix Enabling High-Lateral Resolution Dual Polarity MS Imaging and Lipid C═C Position-Resolved MS 2 Imaging
inferredcites →https://doi.org/10.1021/acs.analchem.0c03502openalex-snapshot
Resolving Modifications on Sphingoid Base and N ‑Acyl Chain of Sphingomyelin Lipids in Complex Lipid Extracts
inferredcites →https://doi.org/10.1021/acs.analchem.1c00575openalex-snapshot
On-Demand Mass Spectrometry Analysis by Miniature Mass Spectrometer
inferredcites →https://doi.org/10.1021/acs.analchem.1c01379openalex-snapshot
Deep Structural Annotation of Glycerolipids by the Charge-Tagging Paterno–Büchi Reaction and Supercritical Fluid Chromatography–Ion Mobility Mass Spectrometry
inferredcites →https://doi.org/10.1021/acs.analchem.6b02834openalex-snapshot
Photochemical Tagging for Quantitation of Unsaturated Fatty Acids by Mass Spectrometry
inferredcites →https://doi.org/10.1021/acs.analchem.7b01870openalex-snapshot
Identification and Quantitation of C═C Location Isomers of Unsaturated Fatty Acids by Epoxidation Reaction and Tandem Mass Spectrometry
inferredcites →https://doi.org/10.1021/acs.analchem.7b04312openalex-snapshot
Rapid Analysis of Unsaturated Fatty Acids on Paper-Based Analytical Devices via Online Epoxidation and Ambient Mass Spectrometry
inferredcites →https://doi.org/10.1021/acs.analchem.8b02021openalex-snapshot
Locating Carbon–Carbon Double Bonds in Unsaturated Phospholipids by Epoxidation Reaction and Tandem Mass Spectrometry
inferredcites →https://doi.org/10.1021/acs.analchem.8b04905openalex-snapshot
Identification of Double Bond Position Isomers in Unsaturated Lipids by m-CPBA Epoxidation and Mass Spectrometry Fragmentation
inferredcites →https://doi.org/10.1021/acs.analchem.8b04935openalex-snapshot
Point-of-Care Tissue Analysis Using Miniature Mass Spectrometer
inferredcites →https://doi.org/10.1021/acs.orglett.0c02316openalex-snapshot
Visible-Light-Enabled Paternò–Büchi Reaction via Triplet Energy Transfer for the Synthesis of Oxetanes
inferredcites →https://doi.org/10.1021/ja00354a055openalex-snapshot
Location of double-bond position in unsaturated fatty acids by negative ion MS/MS
inferredcites →https://doi.org/10.1021/ja056797hopenalex-snapshot
Ozonolysis of Phospholipid Double Bonds during Electrospray Ionization: A New Tool for Structure Determination
inferredcites →https://doi.org/10.1021/jacs.7b06416openalex-snapshot
Pinpointing Double Bond and sn-Positions in Glycerophospholipids via Hybrid 193 nm Ultraviolet Photodissociation (UVPD) Mass Spectrometry
inferredcites →https://doi.org/10.1021/jacs.9b05868openalex-snapshot
Reactive Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Using an Intrinsically Photoreactive Paternò–Büchi Matrix for Double-Bond Localization in Isomeric Phospholipids
inferredcites →https://doi.org/10.1021/jacs.9b12120openalex-snapshot
Visible-Light-Driven [2 + 2] Photocycloadditions between Benzophenone and C═C Bonds in Unsaturated Lipids
inferredcites →https://doi.org/10.1038/35036052openalex-snapshot
Lipid rafts and signal transduction
inferredcites →https://doi.org/10.1038/nature13419openalex-snapshot
Membrane proteins bind lipids selectively to modulate their structure and function
inferredcites →https://doi.org/10.1038/nature20820openalex-snapshot
The role of interfacial lipids in stabilizing membrane protein oligomers
inferredcites →https://doi.org/10.1038/nchem.2172openalex-snapshot
A subset of annular lipids is linked to the flippase activity of an ABC transporter
inferredcites →https://doi.org/10.1038/s41467-018-07963-8openalex-snapshot
Online photochemical derivatization enables comprehensive mass spectrometric analysis of unsaturated phospholipid isomers
inferredcites →https://doi.org/10.1038/s41467-019-14180-4openalex-snapshot
Large-scale lipid analysis with C=C location and sn-position isomer resolving power
inferredcites →https://doi.org/10.1038/s41467-021-23161-5openalex-snapshot
Single-cell lipidomics with high structural specificity by mass spectrometry
inferredcites →https://doi.org/10.1038/s41580-018-0085-zopenalex-snapshot
Dynamics and functions of lipid droplets
inferredcites →https://doi.org/10.1039/c7an01158jopenalex-snapshot
Selective phosphatidylcholine double bond fragmentation and localisation using Paternò–Büchi reactions and ultraviolet photodissociation
inferredcites →https://doi.org/10.1039/d0sc01149eopenalex-snapshot
A visible-light activated [2 + 2] cycloaddition reaction enables pinpointing carbon–carbon double bonds in lipids
inferredcites →https://doi.org/10.1073/pnas.1523356113openalex-snapshot
Identification and quantitation of lipid C=C location isomers: A shotgun lipidomics approach enabled by photochemical reaction
inferredcites →https://doi.org/10.1073/pnas.69.12.3561openalex-snapshot
Formation of Bimolecular Membranes from Lipid Monolayers and a Study of Their Electrical Properties
inferredcites →https://doi.org/10.1146/annurev-biochem-013118-111508openalex-snapshot
Membrane Protein–Lipid Interactions Probed Using Mass Spectrometry
inferredcites →https://doi.org/10.1146/annurev.anchem.111808.073705openalex-snapshot
Advances in Mass Spectrometry for Lipidomics
inferredcites →https://doi.org/10.3390/cancers11070948openalex-snapshot
Stearoyl-CoA Desaturase 1 as a Therapeutic Target for the Treatment of Cancer

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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3d Structural Analysis of Alanyl-Containing Peptides of Silac-Proteomics — an Approach to Stochastic Dynamics
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Structural Characterization of Lipids Using Advanced Mass Spectrometry Approaches
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A Mass Spectrometry Approach Reveals Fatty Acid Isomerism in Tomato Cold Tolerance
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Red Blood Cell Membrane Lipidomics: Potential Biomarkers Detecting Method for Plasma Volume Overload and Major Adverse Cardiovascular Events in Chronic Heart Failure Patients
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Tissue Heterogeneity‐Driven Parallel Acquisition for High‐Coverage MS/MS Imaging of Lipids
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Tissue Heterogeneity‐Driven Parallel Acquisition for High‐Coverage MS/MS Imaging of Lipids
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Exploring Key Lipid Molecules of Primary Dysmenorrhea for Elucidating the Biological Effects of Danggui Shaoyao San Using UPLC ‐Q‐ TOF ‐ MS ‐Based Lipidomics
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A Comprehensive Review of Instrumentation and Applications in Post‐Column and In‐Source Derivatization for LC‐MS
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Structural characterization of sphingomyelins from tissue using electron‐induced dissociation
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Chemical tagging mass spectrometry: an approach for single-cell omics
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Sample preparation for fatty acid analysis in biological samples with mass spectrometry-based strategies
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Differentiation of steroid isomers via derivatization and electron-activated dissociation tandem mass spectrometry
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Isomer-resolved characterization of acylcarnitines reveals alterations in type 2 diabetes
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Untargeted lipidomic deep-profiling of human plasma via high-performance aza-Prilezhaev aziridination-LC-MS: Unraveling C C isomeric signatures of Charcot-Marie-Tooth disease
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Characterization of unsaturated fatty acids with high structural specificity by nuclear magnetic resonance spectroscopy
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In-situ reaction monitoring and kinetics study of photochemical reactions by optical focusing inductive electrospray mass spectrometry
inferred← citeshttps://doi.org/10.1016/j.ijms.2022.116998openalex-snapshot
Structural elucidation and relative quantification of sodium- and potassium-cationized phosphatidylcholine regioisomers directly from tissue using electron induced dissociation
inferred← citeshttps://doi.org/10.1016/j.jlr.2022.100219openalex-snapshot
Deep-lipidotyping by mass spectrometry: recent technical advances and applications
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In-situ sampling of lipids in tissues using a porous membrane microprobe for direct mass spectrometry analysis
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High-confidence structural identification of metabolites relying on tandem mass spectrometry through isomeric identification: A tutorial
inferred← citeshttps://doi.org/10.1016/j.trac.2024.117765openalex-snapshot
Marching toward human lipidome project – Advancement of structural lipidomics
inferred← citeshttps://doi.org/10.1021/acs.analchem.1c05607openalex-snapshot
Chloramine-T-Enabled Mass Spectrometric Analysis of C═C Isomers of Unsaturated Fatty Acids and Phosphatidylcholines in Human Thyroids
inferred← citeshttps://doi.org/10.1021/acs.analchem.2c03505openalex-snapshot
LipidOA: A Machine-Learning and Prior-Knowledge-Based Tool for Structural Annotation of Glycerophospholipids
inferred← citeshttps://doi.org/10.1021/acs.analchem.3c00085openalex-snapshot
Visible-Light Paternò–Büchi Reaction for Lipidomic Profiling at Detailed Structure Levels
inferred← citeshttps://doi.org/10.1021/acs.analchem.3c00722openalex-snapshot
Volume-Corrected Free Energy as a New Criterion for Structural Elucidation in Chemical-Tagging-Based Metabolomics
inferred← citeshttps://doi.org/10.1021/acs.analchem.3c02325openalex-snapshot
Comprehensive Profiling of Amine-Containing Metabolite Isomers with Chiral Phosphorus Reagents
inferred← citeshttps://doi.org/10.1021/acs.analchem.3c02605openalex-snapshot
Expanding Lipidomic Coverage in Multisegment Injection–Nonaqueous Capillary Electrophoresis–Mass Spectrometry via a Convenient and Quantitative Methylation Strategy
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Selective Characterization of Olefins by Paternò–Büchi Reaction with Ultrahigh Resolution Mass Spectrometry
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Development of an Efficient On-Tissue Epoxidation Reaction Mediated by Urea Hydrogen Peroxide for MALDI MS/MS Imaging of Lipid C═C Location Isomers
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Shotgun Lipidomic Profiling of Sebum Lipids via Photocatalyzed Paternò–Büchi Reaction and Ion Mobility-Mass Spectrometry
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Aza-Prilezhaev Aziridination-Enabled Multidimensional Analysis of Isomeric Lipids via High-Resolution U-Shaped Mobility Analyzer–Mass Spectrometry
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Mass Spectrometry Imaging for the Characterization of C═C Localization in Unsaturated Lipid Isomers at the Single-Cell Level
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sn-Position-Resolved Quantification of Aminophospholipids by Isotopic N,N-Dimethyl Leucine Labeling and High-Resolution Ion Mobility Mass Spectrometry
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Universal Photosensitizer for Isomer-Selective Lipid Imaging with High Molecular Coverage
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Revealing Acyl Chain Selectivity of Cis-to-Trans Isomerase through Profiling of C═C Geometry and Location Isomers of Bacterial Lipids
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Direct Infusion Acoustic Droplet Ejection Mass Spectrometry: Enabling High-Throughput Shotgun Lipidomics
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Extreme Ultraviolet Photodissociation Decodes the Chain Modifications of Lipids
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Cross-Validation of Lipid Structure Assignment Using Orthogonal Ion Activation Modalities on the Same Mass Spectrometer
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Mass filtering combined with photochemical derivatization enables high throughput mass spectrometric analysis of unsaturated phosphatidylcholine isomers
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Enthalpic and entropic contributions to interleaflet coupling drive domain registration and antiregistration in biological membrane
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Comprehensive multi-omics analysis revealed that mulberry leaf dietary supplementation can improve the lipo-nutritional quality of pork and regulate gut microbiota in pigs
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Recent developments in ionization techniques for single-cell mass spectrometry
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Plasma lipidomics profiling in predicting the chemo-immunotherapy response in advanced non-small cell lung cancer
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