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Rolling Circle Amplification in Integrated Microsystems: An Uncut Gem toward Massively Multiplexed Pathogen Diagnostics and Genotyping

https://doi.org/10.1021/acs.accounts.1c00438

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What this work says

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Microfluidic magnetic fluidized bed for DNA analysis in continuous flow mode

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Silica bead-based microfluidic device with integrated photodiodes for the rapid capture and detection of rolling circle amplification products in the femtomolar range

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Homogeneous circle-to-circle amplification for real-time optomagnetic detection of SARS-CoV-2 RdRp coding sequence

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Sub-attomole detection of HIV-1 using padlock probes and rolling circle amplification combined with microfluidic affinity chromatography

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Sensitive magnetic biodetection using magnetic multi-core nanoparticles and RCA coils

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Digital Rolling Circle Amplification–Based Detection of Ebola and Other Tropical Viruses

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Circle-to-circle amplification coupled with microfluidic affinity chromatography enrichment for in vitro molecular diagnostics of Zika fever and analysis of anti-flaviviral drug efficacy

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A review of reaction enhancement strategies for isothermal nucleic acid amplification reactions

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Rolling-circle amplification of viral DNA genomes using phi29 polymerase

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Novel Readout Method for Molecular Diagnostic Assays Based on Optical Measurements of Magnetic Nanobead Dynamics

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The Discovery of Rolling Circle Amplification and Rolling Circle Transcription

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Scalable DNA-Based Magnetic Nanoparticle Agglutination Assay for Bacterial Detection in Patient Samples

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Gold Nanowire Based Electrical DNA Detection Using Rolling Circle Amplification

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Mutation detection and single-molecule counting using isothermal rolling-circle amplification

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Protein detection using proximity-dependent DNA ligation assays

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Targeted DNA sequencing and in situ mutation analysis using mobile phone microscopy

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In situ detection and genotyping of individual mRNA molecules

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In situ sequencing for RNA analysis in preserved tissue and cells

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Highly multiplexed simultaneous detection of RNAs and proteins in single cells

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RNA-templated DNA ligation for transcript analysis

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Padlock Probe Assay for Detection and Subtyping of Seasonal Influenza

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A Comprehensive Bibliometric Investigation on Antimicrobials from Fungal Origins with a Biotechnological Perspective

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Nucleic acid amplification strategies for volume-amplified magnetic nanoparticle detection assay

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Nucleic acid testing of SARS-CoV-2: A review of current methods, challenges, and prospects

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Methods for detection and identification of beer-spoilage microbes

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Advances in Genotyping Detection of Fragmented Nucleic Acids

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Rolling Circle Amplification as a Molecular Tool for Spatially Resolved Signal Amplification in Single Molecule Counting Assay

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Recent Strategies for MicroRNA Detection: A Comprehensive Review of SERS-Based Nanobiosensors

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Advances in Foodborne Pathogen Detection: From Conventional Confirmation to Integrated and Intelligent Platforms

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Development of a Pre-Modification Strategy to Overcome Restriction–Modification Barriers and Enhance Genetic Engineering in Lactococcus lactis for Nisin Biosynthesis

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Isothermal Detection Methods for Fungal Pathogens in Closed Environment Agriculture

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Adaptation of a Model Spike Aptamer for Isothermal Amplification-Based Sensing

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DNA Nanotechnology-Enabled Precise Regulation of Nanozymes and Their Applications

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Rapid In-Field Diagnostics: Horizon Scanning and Technology Readiness Level Study With a Technology Pilot study.

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PCR AND OTHER GENOMIC TECHNIQUES APPLIED TO VETERINARY MEDICINE

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Biomedical Techniques in Virology: From Laboratory to Clinical Applications

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