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An Immunosensor Using Electroactive COF as Signal Probe for Electrochemical Detection of Carcinoembryonic Antigen

https://doi.org/10.1021/acs.analchem.1c05426
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Plasmonic Sensing of Oncoproteins without Resonance Shift Using 3D Periodic Nanocavity in Nanocup Arrays
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Frontispiece: Progress and Perspectives on Covalent‐Organic Frameworks (COFs) and Composites for Various Energy Applications
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Electrochemical paper based cancer biosensor using iron oxide nanoparticles decorated PEDOT:PSS
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Universal ratiometric electrochemical biosensing platform based on mesoporous platinum nanocomposite and nicking endonuclease assisted DNA walking strategy
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Label-free photoelectrochemical immunoassay for CEA detection based on CdS sensitized WO3@BiOI heterostructure nanocomposite
inferredcites →https://doi.org/10.1016/j.bios.2017.12.014openalex-snapshot
Electrochemical detection of carcinoembryonic antigen
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Fabrication of sensitive bioelectrode based on atomically thin CVD grown graphene for cancer biomarker detection
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A highly sensitive label-free electrochemical immunosensor based on poly(indole-5-carboxylicacid) with ultra-high redox stability
inferredcites →https://doi.org/10.1016/j.bios.2019.111697openalex-snapshot
A 2D transition metal carbide MXene-based SPR biosensor for ultrasensitive carcinoembryonic antigen detection
inferredcites →https://doi.org/10.1016/j.bios.2019.111769openalex-snapshot
Multiple self-cleaning paper-based electrochemical ratiometric biosensor based on the inner reference probe and exonuclease III-assisted signal amplification strategy
inferredcites →https://doi.org/10.1016/j.bios.2020.112877openalex-snapshot
A passive direct methanol fuel cell as transducer of an electrochemical sensor, applied to the detection of carcinoembryonic antigen
inferredcites →https://doi.org/10.1016/j.bios.2021.113553openalex-snapshot
A novel biosensor based on multienzyme microcapsules constructed from covalent-organic framework
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CEA promoter-regulated oncolytic adenovirus-mediated Hsp70 expression in immune gene therapy for pancreatic cancer
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Highly sensitive immunoassay of carcinoembryonic antigen by capillary electrophoresis with gold nanoparticles amplified chemiluminescence detection
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A label-free aptasensor for carcinoembryonic antigen detection using three-way junction structure and ATMND as a fluorescent probe
inferredcites →https://doi.org/10.1016/j.snb.2018.11.032openalex-snapshot
Ratiometric electrochemical sensing and biosensing based on multiple redox-active state COFDHTA-TTA
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Natural Leukocyte Membrane-Masked Microelectrodes with an Enhanced Antifouling Ability and Biocompatibility for In Vivo Electrochemical Sensing
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Hybridizing Carbon-Based Dot-Capped Manganese Dioxide Nanosheets and Gold Nanoparticles as a Highly Sensitive Surface-Enhanced Raman Scattering Substrate
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Electrochemical Immunosensor for Cardiac Troponin I Detection Based on Covalent Organic Framework and Enzyme-Catalyzed Signal Amplification
inferredcites →https://doi.org/10.1021/acs.analchem.5b03314openalex-snapshot
Exonuclease-Catalyzed Target Recycling Amplification and Immobilization-free Electrochemical Aptasensor
inferredcites →https://doi.org/10.1021/acs.analchem.8b03554openalex-snapshot
Electrochemical-Signal-Amplification Strategy for an Electrochemiluminescence Immunoassay with g-C3N4 as Tags
inferredcites →https://doi.org/10.1021/acs.analchem.9b04185openalex-snapshot
Nanopore-based Strategy for Selective Detection of Single Carcinoembryonic Antigen (CEA) Molecules
inferredcites →https://doi.org/10.1021/acs.analchem.9b04282openalex-snapshot
Ultrasensitive Detection of Exosomes by Target-Triggered Three-Dimensional DNA Walking Machine and Exonuclease III-Assisted Electrochemical Ratiometric Biosensing
inferredcites →https://doi.org/10.1021/acs.analchem.9b04503openalex-snapshot
Faraday-Cage-Type Electrochemiluminescence Immunoassay: A Rise of Advanced Biosensing Strategy
inferredcites →https://doi.org/10.1021/acs.analchem.9b04600openalex-snapshot
Synthesis of a pH-Responsive Functional Covalent Organic Framework via Facile and Rapid One-Step Postsynthetic Modification and Its Application in Highly Efficient N1-Methyladenosine Extraction
inferredcites →https://doi.org/10.1021/acsami.8b21696openalex-snapshot
Electron Highways into Nanochannels of Covalent Organic Frameworks for High Electrical Conductivity and Energy Storage
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Colorimetric Immunosensor Based on Au@g-C3N4-Doped Spongelike 3D Network Cellulose Hydrogels for Detecting α-Fetoprotein
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inferredcites →https://doi.org/10.1021/acsnano.5b00184openalex-snapshot
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inferredcites →https://doi.org/10.1021/ja409421dopenalex-snapshot
β-Ketoenamine-Linked Covalent Organic Frameworks Capable of Pseudocapacitive Energy Storage
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One-Step Construction of Two Different Kinds of Pores in a 2D Covalent Organic Framework
inferredcites →https://doi.org/10.1021/jacs.6b12885openalex-snapshot
Postsynthetically Modified Covalent Organic Frameworks for Efficient and Effective Mercury Removal
inferredcites →https://doi.org/10.1021/jacs.7b04141openalex-snapshot
3D Porphyrin-Based Covalent Organic Frameworks
inferredcites →https://doi.org/10.1038/s41467-020-17018-6openalex-snapshot
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inferredcites →https://doi.org/10.1039/c2cc35645gopenalex-snapshot
CEA fluorescence biosensor based on the FRET between polymer dots and Au nanoparticles
inferredcites →https://doi.org/10.1039/c6ta05784eopenalex-snapshot
A redox-active 2D covalent organic framework with pyridine moieties capable of faradaic energy storage
inferredcites →https://doi.org/10.1039/c7cc01902eopenalex-snapshot
Interfacial synthesis of ordered and stable covalent organic frameworks on amino-functionalized carbon nanotubes with enhanced electrochemical performance
inferredcites →https://doi.org/10.1039/d0cs00017eopenalex-snapshot
Bulk COFs and COF nanosheets for electrochemical energy storage and conversion
inferredcites →https://doi.org/10.1158/1078-0432.ccr-15-2622openalex-snapshot
In Vivo Fluorescence Imaging of the Activity of CEA TCB, a Novel T-Cell Bispecific Antibody, Reveals Highly Specific Tumor Targeting and Fast Induction of T-Cell–Mediated Tumor Killing
inferredcites →https://doi.org/10.1200/jco.2008.26.15_suppl.15654openalex-snapshot
Change of serum CEA or CA19–9 is predictive for chemotherapeutic efficacy in recurrence or metastasis gastric cancer
inferredcites →https://doi.org/10.1200/jco.2013.31.15_suppl.e11511openalex-snapshot
Serum CEA and CA 15-3 levels according to breast cancer subtypes.
inferredcites →https://doi.org/10.1200/jco.2018.36.15_suppl.3525openalex-snapshot
Change in CEA as an early predictor of progression to first-line systemic therapy in metastatic colorectal cancer.
inferredcites →https://doi.org/10.2147/ijn.s286317openalex-snapshot
Simultaneous Detection of VEGF and CEA by Time-Resolved Chemiluminescence Enzyme-Linked Aptamer Assay

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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An efficient electrochemical nano-biosensor based on hydrothermally engineered ultrathin nanostructures of hexagonal boron nitride nanosheets for label-free detection of carcinoembryonic antigen
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A novel electrochemical immunosensor that amplifies Poly(o-phenylenediamine) signal by pH-driven cascade reaction used for alpha-foetoprotein detection
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Ternary electrochemiluminescence quenching effects of CuFe2O4@PDA-MB towards self-enhanced Ru(dcbpy)32+ functionalized 2D metal-organic layer and application in carcinoembryonic antigen immunosensing
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Detection of acetylcholinesterase based on ECL resonance energy transfer between luminol and gold nanoparticle decorated covalent organic framework
inferred← citeshttps://doi.org/10.1016/j.microc.2025.114197openalex-snapshot
A novel FAM-based fluorescent aptasensor with covalent organic framework as quencher for sensitive determination of carcinoembryonic antigen
inferred← citeshttps://doi.org/10.1016/j.microc.2025.114388openalex-snapshot
Development of an electrochemiluminescence aptasensor combining covalent-triazine framework emitter with exonuclease III-driven DNA walker for sensitive CEA detection
inferred← citeshttps://doi.org/10.1016/j.microc.2025.114529openalex-snapshot
Covalent organic frameworks (COFs)-based sensors: advances in environmental monitoring, food safety and biomedicine detection
inferred← citeshttps://doi.org/10.1016/j.microc.2026.117177openalex-snapshot
Trends in Electrochemical Immunosensors for Lung Cancer Detection: A Bibliometric Review Analysis
inferred← citeshttps://doi.org/10.1016/j.microc.2026.117201openalex-snapshot
A flexible electrochemical biosensor based on novel COF-PA-FeNi electroactive nanomaterials for ultrasensitive detection of kanamycin
inferred← citeshttps://doi.org/10.1016/j.microc.2026.118603openalex-snapshot
High-sensitivity Mfn2 electrochemical immunoassay: Early warning of drug-induced cardiotoxicity using a COFs@f-CB/CS nanocomposite interface
inferred← citeshttps://doi.org/10.1016/j.microc.2026.119925openalex-snapshot
Screen-printed carbon electrode functionalized with bifunctional covalent organic framework: A highly sensitive and microvolume electrochemical impedance platform for tau instant detection
inferred← citeshttps://doi.org/10.1016/j.mtchem.2022.101178openalex-snapshot
Fluorescent benzothiazole-based covalent-organic frameworks with intramolecular dual “lock” for ratiometric detection of fenthion
inferred← citeshttps://doi.org/10.1016/j.saa.2022.122022openalex-snapshot
A fluorescent covalent organic framework for visual detection of p-benzoquinone
inferred← citeshttps://doi.org/10.1016/j.saa.2024.124269openalex-snapshot
A papain-based colorimetric catalytic sensing system for immunoassay detection of carcinoembryonic antigen
inferred← citeshttps://doi.org/10.1016/j.seppur.2026.139249openalex-snapshot
Controlled fabrication of β-ketoenamine-based covalent organic framework membranes via organic acid regulation: A comparative investigation
inferred← citeshttps://doi.org/10.1016/j.snb.2022.132933openalex-snapshot
Ultrasensitive “on-off-on” photoelectrochemical aptasensor for tumor biomarker using BiOI/α-Fe2O3 p-n heterojunction arrays by in-situ regulation of electron donor distance
inferred← citeshttps://doi.org/10.1016/j.snb.2023.133340openalex-snapshot
Electrochemical ratiometric dual-signal immunoassay for accurate detection of carcinoembryonic antigen in clinical serum based on rGO-Pd@Au-Thi and Chi-Fc-Au
inferred← citeshttps://doi.org/10.1016/j.snb.2024.136068openalex-snapshot
Construction of phosphatase-like COF-OMe@Valine-CeO2 nanozymes for ultrasensitive electrochemical detection of organophosphorus pesticides
inferred← citeshttps://doi.org/10.1016/j.snb.2025.138488openalex-snapshot
Ultrasensitive multifunctional COF electrochemical biosensor for bacteria detection based on triple-helix molecular switch and Zn2+ -triggered DNAzyme-driven swing-arm robot
inferred← citeshttps://doi.org/10.1016/j.talanta.2023.124489openalex-snapshot
Perylene derivative and persulfate as highly efficient electrochemical system for constructing sensitive amperometric aptasensor
inferred← citeshttps://doi.org/10.1016/j.talanta.2023.124613openalex-snapshot
Covalent organic framework: A state-of-the-art review of electrochemical sensing applications
inferred← citeshttps://doi.org/10.1016/j.talanta.2023.124812openalex-snapshot
Catalytic hairpin assembly-assisted dual-signal amplification platform for ultrasensitive detection of tumor markers and intelligent diagnosis of gastric cancer
inferred← citeshttps://doi.org/10.1016/j.talanta.2024.126330openalex-snapshot
Synthesis of flower-like ZnO nanoparticles for label-free point of care detection of carcinoembryonic antigen
inferred← citeshttps://doi.org/10.1016/j.talanta.2024.127147openalex-snapshot
Construction of electrochemical immunosensors based on Au@MXene and Au@CuS nanocomposites for sensitive detection of carcinoembryonic antigen
inferred← citeshttps://doi.org/10.1016/j.talanta.2025.127546openalex-snapshot
An electrochemical immunosensor for carbohydrate antigen CA125 based on electroactive COFs as a signal probe
inferred← citeshttps://doi.org/10.1016/j.talanta.2026.130251openalex-snapshot
A dual interpenetrating conductive hydrogel based 3D immunointerface for ultrasensitive electrochemical CEA detection
inferred← citeshttps://doi.org/10.1016/j.talanta.2026.130313openalex-snapshot
Trimetallic CoFeZn nanozymes with enhanced peroxidase-mimetic activity for ultrasensitive electrochemical immunosensing of HE4: Toward ovarian cancer monitoring
inferred← citeshttps://doi.org/10.1016/j.trac.2023.116981openalex-snapshot
Early detection of tumour-associated antigens: Assessment of point-of-care electrochemical immunoassays
inferred← citeshttps://doi.org/10.1016/j.trac.2024.117678openalex-snapshot
Metal-organic frameworks (MOFs) and covalent organic frameworks (COFs)-based prototyping of integrated sensing devices for robust analysis
inferred← citeshttps://doi.org/10.1021/acs.analchem.2c04824openalex-snapshot
Aluminum(III)-Based Organic Nanofibrous Gels as an Aggregation-Induced Electrochemiluminescence Emitter Combined with a Rigid Triplex DNA Walker as a Signal Magnifier for Ultrasensitive DNA Assay
inferred← citeshttps://doi.org/10.1021/acs.analchem.3c02266openalex-snapshot
Proximity Amplification-Enabled Electrochemical Analysis of Tumor-Associated Glycoprotein Biomarkers
inferred← citeshttps://doi.org/10.1021/acs.analchem.3c05035openalex-snapshot
Antibody-Protein-Aptamer Electrochemical Biosensor based on Highly Efficient Proximity-Induced DNA Hybridization on Tetrahedral DNA Nanostructure for Sensitive Detection of Insulin-like Growth Factor-1
inferred← citeshttps://doi.org/10.1021/acs.analchem.4c02995openalex-snapshot
Structure Remodeling Strategy for Open-Cage NiFe@Fe-bis-PBA with Enhanced Peroxidase-like Activity To Monitor Tumor Markers
inferred← citeshttps://doi.org/10.1021/acs.analchem.4c04054openalex-snapshot
Glycan-Evocated Metallization for Amplification-Free Electrochemical Detection of Glycoproteins at Low Concentration Levels
inferred← citeshttps://doi.org/10.1021/acs.langmuir.4c00607openalex-snapshot
Functional Interface for Glycoprotein Sensing: Focusing on Biosensors
inferred← citeshttps://doi.org/10.1021/acsanm.3c05742openalex-snapshot
Dispersed Au Nanoparticles Anchored on Covalent Organic Frameworks/Carbon Nanotubes via Self-Reduction for Electrochemical Sensing of Acetaminophen
inferred← citeshttps://doi.org/10.1021/acsanm.6c01174openalex-snapshot
Entropy-Stabilized Redox Synergy in Hollow High-Entropy Alloy Nanorods for Label-Free Electrochemical Immunosensing of Cancer Biomarker
inferred← citeshttps://doi.org/10.1021/acsnano.2c11346openalex-snapshot
Covalent Organic Frameworks: Recent Progress in Biomedical Applications
inferred← citeshttps://doi.org/10.1021/acsomega.3c04198openalex-snapshot
Assessing CO 2 Adsorption Behavior onto Free-Standing, Flexible Organic Framework-PVDF Composite Membrane: An Empirical Modeling and Validation of an Experimental Data Set
inferred← citeshttps://doi.org/10.1021/jacs.4c09259openalex-snapshot
Reticular Chemistry for Enhancing Bioentity Stability and Functional Performance
inferred← citeshttps://doi.org/10.1039/d2nj04336jopenalex-snapshot
Construction of hydrophilic covalent organic frameworks and their fast and efficient adsorption of cationic dyes from aqueous solution
inferred← citeshttps://doi.org/10.1039/d3an00946gopenalex-snapshot
Gold nanoparticle-decorated covalent organic frameworks as amplified light-scattering probes for highly sensitive immunodetection of Salmonella in milk
inferred← citeshttps://doi.org/10.1039/d3an01221bopenalex-snapshot
A bimetallic metal–organic framework with high enzyme-mimicking activity for an integrated electrochemical immunoassay of carcinoembryonic antigen
inferred← citeshttps://doi.org/10.1039/d3an02075dopenalex-snapshot
Unique three-dimensional ordered macroporous dealloyed gold–silver electrochemical sensing platforms for ultrasensitive mercury( ii ) monitoring
inferred← citeshttps://doi.org/10.1039/d3ta04781dopenalex-snapshot
Linker engineering to regulate the fluorescence of hydrazone-linked covalent organic frameworks for the real-time visual detection of norfloxacin and multiple information encryption
inferred← citeshttps://doi.org/10.1039/d4ay01766hopenalex-snapshot
Au nanoparticle-modified hollow carbon spheres as an advanced electrochemical sensing platform for effective detection of homocysteine in human serum
inferred← citeshttps://doi.org/10.1039/d4nj02572eopenalex-snapshot
A quenching electrochemiluminescence energy resonance transfer system based on CdS and COFs for the ultrasensitive detection of CA242
inferred← citeshttps://doi.org/10.1039/d5nj00935aopenalex-snapshot
A novel electrochemical sensor with COF TZT-DVA /CNT@PB nanoflowers for hydrogen peroxide detection
inferred← citeshttps://doi.org/10.1039/d6ay00265jopenalex-snapshot
Construction of a label-free COF/PTh/MB electrochemical immunosensor for the detection of CA-125
inferred← citeshttps://doi.org/10.1039/d6ay01523aopenalex-snapshot
Fabrication of a COF-Ag composite-enabled electrochemical sensing platform for sensitive rutin detection
inferred← citeshttps://doi.org/10.1039/d6cc01675hopenalex-snapshot
No-wash immunosensors based on superhydrophilic covalent organic framework nanosheets with aggregation-induced emission for detecting carbohydrate antigen 19-9
inferred← citeshttps://doi.org/10.1039/d6cc03002eopenalex-snapshot
Recent advancements in covalent organic frameworks as electrochemical and spectroscopic biosensors
inferred← citeshttps://doi.org/10.1080/10408347.2025.2497868openalex-snapshot
Detection of Cancer Biomarkers: Review of Methods and Applications Reported from Analytical Perspective
inferred← citeshttps://doi.org/10.1080/10408398.2023.2230506openalex-snapshot
Covalent organic frameworks assisted for food safety analysis
inferred← citeshttps://doi.org/10.1134/s1023193524010142openalex-snapshot
Diagnosis of Blood Gastric Cancer Biomarkers via Nanomaterial-Based Electrochemical Immunosensor: A Review on Recent Advancements (A Review)
inferred← citeshttps://doi.org/10.1149/1945-7111/ad066aopenalex-snapshot
An Electrochemical Immunosensor Based on GO@CS for Highly Sensitive and Accurate Detection of Cardiovascular Markers-cTn- I
inferred← citeshttps://doi.org/10.1149/1945-7111/ad31f0openalex-snapshot
A Rapid and Easy Procedure of Enzyme Biosensor based on Nitrogen-Doped Graphene for Detection of Methyl Parathion in CHM
inferred← citeshttps://doi.org/10.1155/2022/3541403openalex-snapshot
[Retracted] Expression Levels and Clinical Significance of Serum miR‐497, CEA, CA24‐2, and HBsAg in Patients with Colorectal Cancer
inferred← citeshttps://doi.org/10.1186/s12951-025-03988-6openalex-snapshot
Covalent organic framework-based electrochemical nanosensing: an emerging paradigm for early cancer diagnosis and longitudinal surveillance
inferred← citeshttps://doi.org/10.1364/oe.523513openalex-snapshot
Optical fiber sensing probe for detecting a carcinoembryonic antigen using a composite sensitive film of PAN nanofiber membrane and gold nanomembrane
inferred← citeshttps://doi.org/10.3389/fnano.2026.1796554openalex-snapshot
Lab-on-a-chip nanoarchitectures for oncogene detection and early cancer screening
inferred← citeshttps://doi.org/10.3390/bios12100899openalex-snapshot
A Novel Paper-Based Electrochemical Biosensor Based on N,O-Rich Covalent Organic Frameworks for Carbaryl Detection
inferred← citeshttps://doi.org/10.3390/bios12100904openalex-snapshot
A Paper-Based Electrochemical Sensor Based on PtNP/COFTFPB−DHzDS@rGO for Sensitive Detection of Furazolidone
inferred← citeshttps://doi.org/10.3390/bios15020080openalex-snapshot
A Dual Nano-Signal Probe-Based Electrochemical Immunosensor for the Simultaneous Detection of Two Biomarkers in Gastric Cancer
inferred← citeshttps://doi.org/10.3390/bios15070469openalex-snapshot
Covalent Organic Frameworks for Immunoassays: A Review
inferred← citeshttps://doi.org/10.3390/chemosensors10100407openalex-snapshot
An Ascorbic Acid-Imprinted Poly(o-phenylenediamine)/AuNPs@COFTFPB-NBPDA for Electrochemical Sensing Ascorbic Acid
inferred← citeshttps://doi.org/10.3390/chemosensors10110458openalex-snapshot
Electrochemical Sensors Based on Metal-Porous Carbon Nanozymes for Dopamine, Uric Acid and Furazolidone
inferred← citeshttps://doi.org/10.3390/chemosensors13050164openalex-snapshot
Using BiOI/BiOCl Composite-Enhanced Cathodic Photocurrent and Amplifying Signal Variation in AgI for Developing a Highly Sensitive Photoelectrochemical Immunosensing Platform
inferred← citeshttps://doi.org/10.3390/molecules28135186openalex-snapshot
Homogeneous Electrochemical Aptamer Sensor Based on Two-Dimensional Nanocomposite Probe and Nanochannel Modified Electrode for Sensitive Detection of Carcinoembryonic Antigen
inferred← citeshttps://doi.org/10.3390/molecules30061347openalex-snapshot
In Situ Growth of Au NPs on Nitrogen-Doped Graphene Quantum Dots Decorated Graphene Composites for the Construction of an Electrochemical Immunosensor and Its Application in CEA Detection
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