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Further Insight into the Lability of MeCN Ligands of Cytotoxic Cycloruthenated Compounds: Evidence for the Antisymbiotic Effect Trans to the Carbon Atom at the Ru Center

https://doi.org/10.1021/acs.inorgchem.5b01236
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Outgoing claims: the papers this work cites, builds on, or argues with.

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Synthesis and Reactivity of 2-Aminophenylpalladium(II) Complexes: Insertion Reactions of Oxygen and Carbon Monoxide into Carbon−Palladium Bonds—New Examples of “Transphobia”
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Classical and Non‐Classical Ruthenium‐Based Anticancer Drugs: Towards Targeted Chemotherapy
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Synthesis of Cycloruthenated Compounds as Potential Anticancer Agents
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Cycloruthenated Compounds – Synthesis and Applications
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Induction of caspase 8 and reactive oxygen species by ruthenium-derived anticancer compounds with improved water solubility and cytotoxicity
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Anticancer cyclometalated complexes of platinum group metals and gold
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From bench to bedside – preclinical and early clinical development of the anticancer agent indazolium trans-[tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019 or FFC14A)
inferredcites →https://doi.org/10.1016/j.jinorgbio.2012.12.003openalex-snapshot
Photoinduced ligand exchange and DNA binding of cis-[Ru(phpy)(phen)(CH3CN)2]+ with long wavelength visible light
inferredcites →https://doi.org/10.1016/j.jorganchem.2013.08.032openalex-snapshot
Structural and optical properties of new cyclometalated Ru(II) derived compounds
inferredcites →https://doi.org/10.1016/s0010-8545(99)00184-8openalex-snapshot
Trans-effects in octahedral transition metal complexes
inferredcites →https://doi.org/10.1016/s0022-328x(02)01729-1openalex-snapshot
Mono- and di-nuclear complexes of ortho-palladated and -platinated 4,4′-dimethylazobenzene with bis(diphenylphosphino)methane. More data on transphobia
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Biomedical and Biochemical Applications of Self-Assembled Metallacycles and Metallacages
inferredcites →https://doi.org/10.1021/ic048270wopenalex-snapshot
Synthesis, Characterization, and Electrochemistry of Biorelevant Photosensitive Low-Potential Orthometalated Ruthenium Complexes
inferredcites →https://doi.org/10.1021/ic400835nopenalex-snapshot
Next-Generation Metal Anticancer Complexes: Multitargeting via Redox Modulation
inferredcites →https://doi.org/10.1021/ic50121a052openalex-snapshot
Antisymbiosis and the trans effect
inferredcites →https://doi.org/10.1021/ja00533a057openalex-snapshot
Antitumor agents. Synthesis of novel cis-palladium complexes and their action on supercoiled DNA
inferredcites →https://doi.org/10.1021/jm100020wopenalex-snapshot
Organometallic Anticancer Compounds
inferredcites →https://doi.org/10.1021/om300373topenalex-snapshot
Challenges and Opportunities in the Development of Organometallic Anticancer Drugs
inferredcites →https://doi.org/10.1021/om400611topenalex-snapshot
Rational Synthesis of Heteroleptic Tris(chelate) Ruthenium Complexes [RuII(2-Ph-2′-Py)(L∧L)(L′∧L′)]PF6 by Selective Substitution of the Ligand Trans to the Ruthenated Phenyl Ring
inferredcites →https://doi.org/10.1021/om961094hopenalex-snapshot
The Difficulty of Coordinating MutuallytransPhosphine and Aryl Ligands in Palladium Complexes and Its Relation to Important Coupling Processes. Syntheses and Crystal Structures of a Family of Palladium Phosphino, Triflato, Perchlorato, and Aquo-2-(arylazo)aryl Complexes
inferredcites →https://doi.org/10.1021/om9901067openalex-snapshot
An Effective Route to Cycloruthenated N-Ligands under Mild Conditions
inferredcites →https://doi.org/10.1039/b409887kopenalex-snapshot
Pseudo-rotation mechanism for fast olefin exchange and substitution processes at orthometalated C,N-complexes of platinum(ii)
inferredcites →https://doi.org/10.1039/b601840hopenalex-snapshot
Metal-based antitumour drugs in the post genomic era
inferredcites →https://doi.org/10.1039/b905798fopenalex-snapshot
A categorization of metal anticancer compounds based on their mode of action
inferredcites →https://doi.org/10.1039/c1mt00123jopenalex-snapshot
Advances in metal–carbene complexes as potent anti-cancer agents
inferredcites →https://doi.org/10.1039/c2dt31601copenalex-snapshot
The prevalence of metal-based drugs as therapeutic or diagnostic agents: beyond platinum
inferredcites →https://doi.org/10.1039/c4cs00063copenalex-snapshot
Anti-cancer palladium complexes: a focus on PdX 2 L 2 , palladacycles and related complexes
inferredcites →https://doi.org/10.1098/rsta.2012.0135openalex-snapshot
Cytotoxicity of cyclometallated ruthenium complexes: the role of ligand exchange on the activity
inferredcites →https://doi.org/10.1107/s0021889898007717openalex-snapshot
SIR 97: a new tool for crystal structure determination and refinement
inferredcites →https://doi.org/10.1107/s0108767307043930openalex-snapshot
A short history of SHELX
inferredcites →https://doi.org/10.1107/s0108767390000277openalex-snapshot
Phase annealing in SHELX-90: direct methods for larger structures
inferredcites →https://doi.org/10.1107/s090744490804362xopenalex-snapshot
Structure validation in chemical crystallography
inferredcites →https://doi.org/10.1124/jpet.105.089342openalex-snapshot
Ruthenium (II)-Derived Organometallic Compounds Induce Cytostatic and Cytotoxic Effects on Mammalian Cancer Cell Lines through p53-Dependent and p53-Independent Mechanisms
inferredcites →https://doi.org/10.1158/0008-5472.can-08-4408openalex-snapshot
A Ruthenium-Containing Organometallic Compound Reduces Tumor Growth through Induction of the Endoplasmic Reticulum Stress Gene CHOP
inferredcites →https://doi.org/10.1158/1078-0432.ccr-03-0746openalex-snapshot
A Phase I and Pharmacological Study with Imidazolium- trans- DMSO-imidazole-tetrachlororuthenate, a Novel Ruthenium Anticancer Agent
inferredcites →https://doi.org/10.2174/157018008783406714openalex-snapshot
Evaluation of the Ability of an Organic Derivative of Ruthenium(II) to Reinforce the Cytotoxicity of Fast Neutron Against Malignant Cells in Culture
inferredcites →https://doi.org/10.2533/chimia.2007.692openalex-snapshot
Ruthenium Anticancer Compounds: Challenges and Expectations

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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inferred← citeshttps://doi.org/10.1002/ejic.201601216openalex-snapshot
The Fate of Cycloruthenated Compounds: From C–H Activation to Innovative Anticancer Therapy
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Quinazoline‐Directed C–H Bond Functionalization Catalyzed by Ruthenium(II) Carboxylate – Construction of Polyconjugated Aryl‐Heteroaryl Systems
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Metal-Carbon Bonds of Heavier Group 7 and 8 Metals (Tc, Re, Ru, Os): Mononuclear Tc/Re/Ru/Os Complexes With Metal-Carbon Bonds
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Geometrical Isomerization and Acceptorless Dehydrogenative Alcohol Oxidation Based on Pyrrole-Based Ru(Ⅱ) Complexes
inferred← citeshttps://doi.org/10.1016/j.jorganchem.2015.10.013openalex-snapshot
Synthesis and comparative behavior of ruthena(II)cycles bearing benzene ligand in the radical polymerization of styrene and vinyl acetate
inferred← citeshttps://doi.org/10.1016/j.jorganchem.2016.09.031openalex-snapshot
Mixed heteropentadienyl and N-heterocyclic carbene ruthenium(II) complexes: Synthesis and transfer hydrogenation catalysis
inferred← citeshttps://doi.org/10.1016/j.jorganchem.2017.05.022openalex-snapshot
Trans-C versus Cis-C thermally induced isomerisation of a terpyridine adduct of cytotoxic cycloruthenated compound
inferred← citeshttps://doi.org/10.1016/j.jorganchem.2019.02.022openalex-snapshot
Very strong trans effect in ruthenacyclic carbamoyl complexes leads to ligand redistribution in phosphine derivatives
inferred← citeshttps://doi.org/10.1016/j.tetlet.2017.05.053openalex-snapshot
Pd(II)-catalyzed aerobic intermolecular 1,4-diamination of conjugated dienes: A regioselective [4+4] annulation for the construction of medium-ring 1,6-benzodiazocine derivatives
inferred← citeshttps://doi.org/10.1021/acs.inorgchem.1c03770openalex-snapshot
Dissociation of Bipyridine and Coordination with Nitrosyl: Cyclometalated Ruthenium Nitrosyl Complex
inferred← citeshttps://doi.org/10.1021/acs.inorgchem.3c03671openalex-snapshot
Follow-Up Study of Trans-C to Cis-C Thermally or Photochemically Induced Isomerization of Terpyridine Adducts of Cycloruthenated 2-Aryl-2′-pyridine Compounds
inferred← citeshttps://doi.org/10.1021/acs.inorgchem.6c00951openalex-snapshot
Impact of Ligand Asymmetry in Ru(II)-Polypyridyl Complexes of 2-Picolyl Amine/Imine: Divergent Stimuli-Responsive Reactivity Profiles among Geometrical Isomers
inferred← citeshttps://doi.org/10.1039/c8qo01288aopenalex-snapshot
Mechanistic study of the solvent-controlled Pd( ii )-catalyzed chemoselective intermolecular 1,2-aminooxygenation and 1,2-oxyamination of conjugated dienes
inferred← citeshttps://doi.org/10.3390/polym12081663openalex-snapshot
Synthesis of Poly(2-Acrylamido-2-Methylpropane Sulfonic Acid) and its Block Copolymers with Methyl Methacrylate and 2-Hydroxyethyl Methacrylate by Quasiliving Radical Polymerization Catalyzed by a Cyclometalated Ruthenium(II) Complex
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