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Potent Inhibition of Thioredoxin Reductase by the Rh Derivatives of Anticancer M(arene/Cp*)(NHC)Cl2Complexes

https://doi.org/10.1021/acs.inorgchem.9b03640
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inferred← citeshttps://doi.org/10.1021/acs.inorgchem.3c03471openalex-snapshot
Potent Half-Sandwich 16-/18-Electron Iridium(III) and Ruthenium(II) Anticancer Complexes with Readily Available Amine–Imine Ligands
inferred← citeshttps://doi.org/10.1021/acs.inorgchem.4c03975openalex-snapshot
Triphenylphosphine-Modified Iridium III , Rhodium III , and Ruthenium II Complexes to Achieve Enhanced Anticancer Selectivity by Targeting Mitochondria
inferred← citeshttps://doi.org/10.1021/acs.inorgchem.4c05599openalex-snapshot
Systematic Investigation of Coordination Chemistry in Iridium(III) and Ruthenium(II) Complexes Derived from Pyridyl–Amine Ligands and Their Anticancer Evaluation
inferred← citeshttps://doi.org/10.1021/acs.inorgchem.6c01471openalex-snapshot
Half-Sandwich Ir(III) and Ru(II) Complexes Featuring a Coumarin-Based Chelating Core for Mitochondrial-Targeted Anticancer Activity
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.1c01441openalex-snapshot
Structural Modification of Aminophenylarsenoxides Generates Candidates for Leukemia Treatment via Thioredoxin Reductase Inhibition
inferred← citeshttps://doi.org/10.1021/acs.organomet.1c00019openalex-snapshot
Hetero- and Homobimetallic Complexes Bridged by a Bis(NHC) Ligand: Synthesis via Selective Sequential Metalation and Catalytic Applications in Tandem Organic Transformations
inferred← citeshttps://doi.org/10.1021/acs.organomet.1c00166openalex-snapshot
Synthesis, Characterization, and Antimicrobial Activity of RhIII and IrIII N-Heterocyclic Carbene Piano-Stool Complexes
inferred← citeshttps://doi.org/10.1021/acs.organomet.1c00572openalex-snapshot
16-Electron Half-Sandwich Rhodium(III), Iridium(III), and Ruthenium(II) Complexes as Lysosome-Targeted Anticancer Agents
inferred← citeshttps://doi.org/10.1021/acs.organomet.3c00430openalex-snapshot
Rhodium(I) Complexes Containing the N^N^N-Chelating Ligand: Synthesis, Structure, and Biological Activity
inferred← citeshttps://doi.org/10.1021/acsorginorgau.2c00035openalex-snapshot
Triazolyl- vs Pyridyl-Functionalized N-Heterocyclic Carbene Complexes: Impact of the Pendant N-Donor Ligand on Intramolecular C–C Bond Formation
inferred← citeshttps://doi.org/10.1039/d1cc02740aopenalex-snapshot
Exploring the stability of the NHC–metal bond using thiones as probes
inferred← citeshttps://doi.org/10.1039/d2dt01929aopenalex-snapshot
Cell nucleus localization and high anticancer activity of quinoline–benzopyran rhodium( iii ) metal complexes as therapeutic and fluorescence imaging agents
inferred← citeshttps://doi.org/10.1039/d2dt02539fopenalex-snapshot
Platinum(terpyridine) complexes with N-heterocyclic carbene co-ligands: high antiproliferative activity and low toxicity in vivo
inferred← citeshttps://doi.org/10.1039/d4dt01646gopenalex-snapshot
Towards building blocks for metallosupramolecular structures: non-symmetrically-functionalised ferrocenyl compounds
inferred← citeshttps://doi.org/10.1039/d4dt03219eopenalex-snapshot
A comprehensive survey of cytotoxic active half-sandwich Ir( iii ) complexes: structural perspective, and mechanism of action
inferred← citeshttps://doi.org/10.1039/d4qi02472aopenalex-snapshot
Anticancer iridium( iii ) cyclopentadienyl complexes
inferred← citeshttps://doi.org/10.1039/d5dt01851jopenalex-snapshot
Biochemical assays for evaluating anticancer activity and validating mechanisms of action in coordination/organometallic compounds: a review
inferred← citeshttps://doi.org/10.1039/d5dt02646fopenalex-snapshot
Quantum chemical insights into reactivity trends of half-sandwich Os( ii ), Ru( ii ), Ir( iii ) and Rh( iii ) complexes: hydrolysis, cysteine binding, and NADH oxidation from DFT analysis
inferred← citeshttps://doi.org/10.1039/d5qi02457aopenalex-snapshot
Competitive LC-MS/MS assay to investigate protein metalation dynamics
inferred← citeshttps://doi.org/10.1039/d5sc02925bopenalex-snapshot
X-ray fluorescence microscopy and X-ray absorption spectroscopy reveal the stability of the plecstatin-1 scaffold in biological model systems: comparison of Ru, Os and Ir analogues
inferred← citeshttps://doi.org/10.1080/13543776.2021.1899160openalex-snapshot
Thioredoxin reductase inhibitors: updated patent review (2017-present)
inferred← citeshttps://doi.org/10.1128/spectrum.00759-26openalex-snapshot
A nickel N-heterocyclic biscarbene complex derived from caffeine enhances fluconazole efficacy against Nakaseomyces glabratus
inferred← citeshttps://doi.org/10.2139/ssrn.5271903openalex-snapshot
Four New Rhodium(Iii)-Triphenylphosphine Coordination Compounds with 5-Halogenate-8-Hydroxyquinoline as Ligands: Synthesis, Characterization, Cytotoxic Activity and Mechanism of Action
inferred← citeshttps://doi.org/10.2174/0113895575390561251121044125openalex-snapshot
Recent Developments in Heterocyclic Derivatives as Novel Cancer Therapeutics: From 2020-2024
inferred← citeshttps://doi.org/10.3389/fchem.2022.967337openalex-snapshot
Targeting of the intracellular redox balance by metal complexes towards anticancer therapy
inferred← citeshttps://doi.org/10.3390/inorganics9040026openalex-snapshot
Anticancer Half-Sandwich Rhodium(III) Complexes
inferred← citeshttps://doi.org/10.3390/molecules26144282openalex-snapshot
Evaluation of Ruthenium(II) N-Heterocyclic Carbene Complexes as Antibacterial Agents and Inhibitors of Bacterial Thioredoxin Reductase
inferred← citeshttps://doi.org/10.3390/molecules27010148openalex-snapshot
Metal Complexes or Chelators with ROS Regulation Capacity: Promising Candidates for Cancer Treatment
inferred← citeshttps://doi.org/10.3390/molecules28062671openalex-snapshot
Cytotoxicity Evaluation of Unmodified Paddlewheel Dirhodium(II,II)-Acetate/-Formamidinate Complexes and Their Axially Modified Low-Valent Metallodendrimers
inferred← citeshttps://doi.org/10.3390/pharmaceutics14050954openalex-snapshot
Bioactivity and Development of Small Non-Platinum Metal-Based Chemotherapeutics
inferred← citeshttps://doi.org/10.5772/intechopen.101729openalex-snapshot
The Anticancer Profile of Benzimidazolium Salts and Their Metal Complexes
inferred← citeshttps://doi.org/10.64898/2026.03.03.709283openalex-snapshot
A Nickel N-Heterocyclic Biscarbene Complex Derived from Caffeine Enhances Fluconazole Efficacy against Candida glabrata
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