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The Role of Trehalose for the Stabilization of Proteins

https://doi.org/10.1021/acs.jpcb.6b02517
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Outgoing claims: the papers this work cites, builds on, or argues with.

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Optimization of Storage Stability of Lyophilized Actin Using Combinations of Disaccharides and Dextran
inferredcites →https://doi.org/10.1002/bip.360340713openalex-snapshot
IR and Raman spectroscopic studies of the interaction of trehalose with hen egg white lysozyme
inferredcites →https://doi.org/10.1002/pro.3openalex-snapshot
Effect of trehalose on protein structure
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Trehalose–protein interaction in aqueous solution
inferredcites →https://doi.org/10.1002/prot.20414openalex-snapshot
Molecular dynamics simulation of sucrose‐ and trehalose‐coated carboxy‐myoglobin
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Comparison of Glycerol, Other Polyols, Trehalose, and Raffinose to Provide a Defined Cryoprotectant Medium for Mouse Sperm Cryopreservation
inferredcites →https://doi.org/10.1007/bf00688788openalex-snapshot
Biochemical adaption for freezing tolerance in the wood frog,Rana sylvatica
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Glycerol uptake by erythrocytes from warm- and cold-acclimated Cope’s gray treefrogs
inferredcites →https://doi.org/10.1007/s00360-011-0561-7openalex-snapshot
Skin ice nucleators and glycerol in the freezing-tolerant frog Litoria ewingii
inferredcites →https://doi.org/10.1007/s10973-008-9307-5openalex-snapshot
Effect of sucrose on BSA denatured aggregation at high concentration studied by the iso-conversional method and the master plots method
inferredcites →https://doi.org/10.1007/s10973-008-9490-4openalex-snapshot
Calorimetric study of myoglobin embedded in trehalose-water matrixes
inferredcites →https://doi.org/10.1016/0305-1978(90)90044-gopenalex-snapshot
Comparison of free sugars in growing and desiccated plants of Selaginella lepidophylla
inferredcites →https://doi.org/10.1016/j.carres.2005.01.036openalex-snapshot
Influence of homologous disaccharides on the hydrogen-bond network of water: complementary Raman scattering experiments and molecular dynamics simulations
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Optimization of cryoprotectant loading into murine and human oocytes
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Lessons from nature: the role of sugars in anhydrobiosis
inferredcites →https://doi.org/10.1021/bi00435a044openalex-snapshot
An infrared spectroscopic study of the interactions of carbohydrates with dried proteins
inferredcites →https://doi.org/10.1021/ie0513503openalex-snapshot
Solid-State Stabilization of α-Chymotrypsin and Catalase with Carbohydrates
inferredcites →https://doi.org/10.1021/j100345a006openalex-snapshot
Phase relations and vitrification in saccharide-water solutions and the trehalose anomaly
inferredcites →https://doi.org/10.1021/jp0677288openalex-snapshot
A Comparative Study of Carboxy Myoglobin in Saccharide−Water Systems by Molecular Dynamics Simulation
inferredcites →https://doi.org/10.1021/jp1089867openalex-snapshot
Role of Solvent for the Dynamics and the Glass Transition of Proteins
inferredcites →https://doi.org/10.1021/jp201378yopenalex-snapshot
Protein Thermal Denaturation and Matrix Glass Transition in Different Protein−Trehalose−Water Systems
inferredcites →https://doi.org/10.1021/jp3054197openalex-snapshot
Thermal Aggregation of Bovine Serum Albumin in Trehalose and Sucrose Aqueous Solutions
inferredcites →https://doi.org/10.1021/jp961139sopenalex-snapshot
α,α-Trehalose−Water Solutions. 1. Hydration Phenomena and Anomalies in the Acoustic Properties
inferredcites →https://doi.org/10.1021/js9800174openalex-snapshot
Sugar–polymer hydrogen bond interactions in lyophilized amorphous mixtures
inferredcites →https://doi.org/10.1021/la046974copenalex-snapshot
Lipid Phase Transition in Saccharide-Coated Cholate-Containing Liposomes: Coupling to the Surrounding Matrix
inferredcites →https://doi.org/10.1038/nmat1681openalex-snapshot
Organization and mobility of water in amorphous and crystalline trehalose
inferredcites →https://doi.org/10.1038/srep01218openalex-snapshot
Microscopic mechanism of protein cryopreservation in an aqueous solution with trehalose
inferredcites →https://doi.org/10.1063/1.1518960openalex-snapshot
Protein–trehalose–water structures in trehalose coated carboxy-myoglobin
inferredcites →https://doi.org/10.1063/1.1828041openalex-snapshot
Dynamics from picoseconds to nanoseconds of trehalose in aqueous solutions as seen by quasielastic neutron scattering
inferredcites →https://doi.org/10.1107/s0907444994014009openalex-snapshot
Use of glycerol, polyols and other protein structure stabilizing agents in protein crystallization
inferredcites →https://doi.org/10.1146/annurev.physiol.60.1.73openalex-snapshot
THE ROLE OF VITRIFICATION IN ANHYDROBIOSIS

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Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Molecular level insight into the counteraction of trehalose on the activity as well as denaturation of lysozyme induced by guanidinium chloride
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Comparative study of molecular mechanisms of sucrose & trehalose mediated protection and stabilization of Escherichia coli lipid membrane during desiccation
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Orodispersible films based on blends of trehalose and pullulan for protein delivery
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Chemical-free recovery of protein from cow manure digestate solid and antioxidant activity of recovered protein
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Characterization of textural, rheological, thermal, microstructural, and water mobility in wheat flour dough and bread affected by trehalose
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Rapid sucrose monitoring in green coffee samples using multienzymatic biosensor
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Trehalose mitigates freeze–thaw-induced gluten network deterioration by modulating aggregation behavior and molecular conformation
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Starch-derived oligosaccharides as prebiotics in innovative functional foods
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Antagonistic yeast and trehalose-enriched gelatin film: A bioactive antifungal packaging film for cherry tomato preservation
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Trehalose promotes biological fitness of fungi
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Trehalose mediated stabilisation of cellobiase aggregates from the filamentous fungus Penicillium chrysogenum
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Formulation parameters governing sustained protein delivery from degradable viscous liquid aliphatic polycarbonates
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Tableting properties of freeze-dried trehalose: Physico-chemical and mechanical investigation
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Diluent Containing Dimethylformamide Added With Sucrose Improves In Vitro Quality After Freezing/Thawing Stallion Sperm
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Combined effect of equimolal osmolytes trehalose and glycine on stability of hen egg-white lysozyme: Quantitative mechanistic aspects
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Starch–sucrose metabolism and phenylpropanoid biosynthesis pathways play crucial regulatory roles in extending the postharvest longevity of Lilium brownii var. viridulum bulbs
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Development and application of metal chelate-epoxy bifunctional loofah sponge for the purification and immobilization of recombinant trehalose synthase
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inferred← citeshttps://doi.org/10.1021/acs.jpcb.6b10556openalex-snapshot
Structure of Aqueous Trehalose Solution by Neutron Diffraction and Structural Modeling
inferred← citeshttps://doi.org/10.1021/acs.jpcb.7b07266openalex-snapshot
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inferred← citeshttps://doi.org/10.1021/acs.jpcb.8b02856openalex-snapshot
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Bioprotection Can Be Tuned with a Proper Protein/Saccharide Ratio: The Case of Solid Amorphous Matrices
inferred← citeshttps://doi.org/10.1021/acs.jpcb.9b01856openalex-snapshot
Mechanism of Trehalose-Induced Protein Stabilization from Neutron Scattering and Modeling
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Structural Comparison between Sucrose and Trehalose in Aqueous Solution
inferred← citeshttps://doi.org/10.1021/acs.jpcb.9b11190openalex-snapshot
Protein Preferential Solvation in Water:Glycerol Mixtures
inferred← citeshttps://doi.org/10.1021/acs.jpclett.1c02379openalex-snapshot
β-Hairpin Miniprotein Stabilization in Trehalose Glass Is Facilitated by an Emergent Compact Non-Native State
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inferred← citeshttps://doi.org/10.1021/acsabm.5c02236openalex-snapshot
Hydration Shell of PEO–PPO–PEO Block Copolymer Assembly Controls the Modulation of Protein Aggregation: Synergistic Inhibition of Fibrillation Using Trehalose and Protection from Cu 2+ -Induced Fibrillation
inferred← citeshttps://doi.org/10.1021/acsabm.6c00990openalex-snapshot
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inferred← citeshttps://doi.org/10.1021/acsabm.8b00769openalex-snapshot
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Sucrose versus Trehalose: Observations from Comparative Study Using Molecular Dynamics Simulations
inferred← citeshttps://doi.org/10.1021/acsomega.6c00106openalex-snapshot
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inferred← citeshttps://doi.org/10.1021/jacs.7b10230openalex-snapshot
Selective Radical Trifluoromethylation of Native Residues in Proteins
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Hyperthermostable cube-shaped assembly in water
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Paper-based nucleic acid amplification tests for point-of-care diagnostics
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Revival of collective water structure and dynamics in reverse micelles brought about by protein encapsulation
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The protein–water nuclear Overhauser effect (NOE) as an indirect microscope for molecular surface mapping of interaction patterns
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inferred← citeshttps://doi.org/10.1039/d0cp03281fopenalex-snapshot
Stabilization of proteins embedded in sugars and water as studied by dielectric spectroscopy
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Trehalose matrices for high temperature dynamic nuclear polarization enhanced solid state NMR
inferred← citeshttps://doi.org/10.1039/d2nj00677dopenalex-snapshot
Improvement of collagen self-assembly and thermal stability in the presence of trehalose
inferred← citeshttps://doi.org/10.1039/d3bm01301dopenalex-snapshot
Botulinum toxin A dissolving microneedles for hyperhidrosis treatment: design, formulation and in vivo evaluation
inferred← citeshttps://doi.org/10.1039/d3cp03357kopenalex-snapshot
Osmolyte induced protein stabilization: modulation of associated water dynamics might be a key factor
inferred← citeshttps://doi.org/10.1039/d3lp00226hopenalex-snapshot
Uniform trehalose nanogels for glucagon stabilization
inferred← citeshttps://doi.org/10.1039/d3na00002hopenalex-snapshot
Design of self-assembled glycopolymeric zwitterionic micelles as removable protein stabilizing agents
inferred← citeshttps://doi.org/10.1039/d3ra06270hopenalex-snapshot
Curcumin-loaded porous particles functionalized with pH-responsive cell-penetrating peptide for colorectal cancer targeted drug delivery
inferred← citeshttps://doi.org/10.1039/d4ra01171fopenalex-snapshot
The inhibition of fibril formation of lysozyme by sucrose and trehalose
inferred← citeshttps://doi.org/10.1039/d4tb02704copenalex-snapshot
Trehalose-releasing nanogels reduce α-synuclein-induced Lewy body-like inclusions in primary mouse hippocampal neurons
inferred← citeshttps://doi.org/10.1039/d5an00800jopenalex-snapshot
Development of a fully paper-based device for quantitative detection of digoxin at the point of care
inferred← citeshttps://doi.org/10.1039/d5nr05299hopenalex-snapshot
The nature of trehalose–protein interactions in aqueous solutions revealed by neutron scattering
inferred← citeshttps://doi.org/10.1063/1.4966189openalex-snapshot
Computational solvation dynamics of oxyquinolinium betaine linked to trehalose
inferred← citeshttps://doi.org/10.1080/00268976.2019.1640400openalex-snapshot
The role of disaccharides for protein–protein interactions – a SANS study
inferred← citeshttps://doi.org/10.1080/07373937.2024.2366512openalex-snapshot
Thermal stabilization of biologics inside glass vials using light-assisted drying (LAD)
inferred← citeshttps://doi.org/10.1080/10409238.2020.1810623openalex-snapshot
Control of electron transfer by protein dynamics in photosynthetic reaction centers
inferred← citeshttps://doi.org/10.1080/87559129.2020.1768403openalex-snapshot
Role of Cryoprotectants in Surimi and Factors Affecting Surimi Gel Properties: A Review
inferred← citeshttps://doi.org/10.1088/1755-1315/1137/1/012036openalex-snapshot
The role of dryoprotectants on the quality of surimi powder of red tilapia
inferred← citeshttps://doi.org/10.1089/bio.2020.0167openalex-snapshot
Trehalose Attenuates Detrimental Effects of Freeze-Drying on Human Sperm Parameters
inferred← citeshttps://doi.org/10.1091/mbc.e17-04-0257openalex-snapshot
Desiccation tolerance: an unusual window into stress biology
inferred← citeshttps://doi.org/10.1093/biolre/ioaf203openalex-snapshot
Effects of microwave-assisted dehydration on the structure and function of ovarian cortex in the domestic cat model: new insights for future storage of living tissues at ambient temperatures
inferred← citeshttps://doi.org/10.1093/g3journal/jkae215openalex-snapshot
Evaluating cellular roles and phenotypes associated with trehalose degradation genes in Saccharomyces cerevisiae
inferred← citeshttps://doi.org/10.1093/jb/mvae048openalex-snapshot
Neurodegenerative diseases associated with the disruption of proteostasis and their therapeutic strategies using chemical chaperones
inferred← citeshttps://doi.org/10.1101/2022.10.04.510657openalex-snapshot
Relevance of the viral Spike protein/cellular Estrogen Receptor-α interaction for endothelial-based coagulopathy induced by SARS-CoV-2
inferred← citeshttps://doi.org/10.1111/evj.14539openalex-snapshot
A comparison of the efficacy of three commercial human embryo vitrification kits for cryopreservation of in vivo produced equine embryos
inferred← citeshttps://doi.org/10.1111/febs.14309openalex-snapshot
Trehalose acts as a uridine 5′‐diphosphoglucose‐competitive inhibitor of trehalose 6‐phosphate synthase in Corynebacterium glutamicum
inferred← citeshttps://doi.org/10.1111/rda.13221openalex-snapshot
Developmental competence of in vitro matured ovine oocytes vitrified in solutions with different concentrations of trehalose
inferred← citeshttps://doi.org/10.1117/12.2647328openalex-snapshot
Light-assisted drying (LAD) for anhydrous preservation of biologics: processing of samples inside glass lyophilization vials
inferred← citeshttps://doi.org/10.1134/s0006297917110049openalex-snapshot
Temperature dependence of tryptophan fluorescence lifetime in aqueous glycerol and trehalose solutions
inferred← citeshttps://doi.org/10.1134/s1607672917060072openalex-snapshot
Influence of trehalose on high-temperature stability of the photosynthetic reaction centers
inferred← citeshttps://doi.org/10.1134/s199079312303020xopenalex-snapshot
Temperature Dependence of the Nonlinear Dynamics of the Deactivation of Excited States of Tryptophan in Various Media
inferred← citeshttps://doi.org/10.1186/s12864-025-11475-3openalex-snapshot
Evolution and amplification of the trehalose-6-phosphate synthase gene family in Theaceae
inferred← citeshttps://doi.org/10.1186/s40643-021-00406-1openalex-snapshot
Chemical-free recovery of crude protein from livestock manure digestate solid by thermal hydrolysis
inferred← citeshttps://doi.org/10.1246/bcsj.20180008openalex-snapshot
Unresolved Issues that Remain in Molecular Self-Assembly
inferred← citeshttps://doi.org/10.1262/jrd.2019-058openalex-snapshot
Effect of trehalose on the preservation of freeze-dried mice spermatozoa at room temperature
inferred← citeshttps://doi.org/10.1364/cleo_at.2024.jtu2a.180openalex-snapshot
Light-Assisted Drying (LAD) for the Stabilization of Biologics at Ambient Temperature
inferred← citeshttps://doi.org/10.1371/journal.pone.0224765openalex-snapshot
Identifying resurrection genes through the differentially expressed genes between Selaginella tamariscina (Beauv.) spring and Selaginella moellendorffii Hieron under drought stress
inferred← citeshttps://doi.org/10.2139/ssrn.5475565openalex-snapshot
Trehalose Coating for the Improved Raw Food Quality of Salmon under Ultra-High Pressure Treatment: Texture, Flavor and Safety
inferred← citeshttps://doi.org/10.26434/chemrxiv.11302397openalex-snapshot
On Protein Preferential Solvation in Water:Glycerol Mixtures
inferred← citeshttps://doi.org/10.31857/s0207401x23060055openalex-snapshot
Температурная зависимость нелинейного характера динамики дезактивации возбужденных состояний триптофана в различных средах
inferred← citeshttps://doi.org/10.3382/ps/pez196openalex-snapshot
Sucrose increases the quality and fertilizing ability of cryopreserved chicken sperms in contrast to raffinose
inferred← citeshttps://doi.org/10.3389/fvets.2023.1301186openalex-snapshot
Supplementing semen extenders with a combination of phosphorus and vitamin B12 Improves post-thawed cryopreserved rooster semen quality
inferred← citeshttps://doi.org/10.3390/agronomy11122521openalex-snapshot
Optimization of Growing Medium and Preservation Methods for Plant Beneficial Bacteria, and Formulating a Microbial Biopreparation for Raspberry Naturalization
inferred← citeshttps://doi.org/10.3390/biomedicines8100425openalex-snapshot
Development of a Multifunctional Bioerodible Nanocomposite Containing Metronidazole and Curcumin to Apply on L-PRF Clot to Promote Tissue Regeneration in Dentistry
inferred← citeshttps://doi.org/10.3390/biophysica2040040openalex-snapshot
A Long Journey into the Investigation of the Structure–Dynamics–Function Paradigm in Proteins through the Activities of the Palermo Biophysics Group
inferred← citeshttps://doi.org/10.3390/cosmetics13040196openalex-snapshot
Trehalose in an Emulsion-Based Carrier: Effects on Skin Hydration and Transepidermal Water Loss
inferred← citeshttps://doi.org/10.3390/cosmetics6040062openalex-snapshot
Evaluation of the Filming and Protective Properties of a New Trehalose and Ceramides Based Ingredient
inferred← citeshttps://doi.org/10.3390/fermentation8040166openalex-snapshot
NTH2 1271_1272delTA Gene Disruption Results in Salt Tolerance in Saccharomyces cerevisiae
inferred← citeshttps://doi.org/10.3390/genes15010039openalex-snapshot
Genome-Wide Identification of Trehalose-6-phosphate Synthase (TPS) Gene Family Reveals the Potential Role in Carbohydrate Metabolism in Peach
inferred← citeshttps://doi.org/10.3390/ijms22052496openalex-snapshot
“Water Association” Band in Saccharide Amorphous Matrices: Role of Residual Water on Bioprotection
inferred← citeshttps://doi.org/10.3390/ijms23179657openalex-snapshot
The Effect of Trehalose Coating for Magnetite Nanoparticles on Stability of Egg White Lysozyme
inferred← citeshttps://doi.org/10.3390/life10050060openalex-snapshot
Trehalose Effect on The Aggregation of Model Proteins into Amyloid Fibrils
inferred← citeshttps://doi.org/10.3390/magnetochemistry4040050openalex-snapshot
Biomolecular EPR Meets NMR at High Magnetic Fields
inferred← citeshttps://doi.org/10.3390/ph14060553openalex-snapshot
Equine Mesenchymal Stem/Stromal Cells Freeze-Dried Secretome (Lyosecretome) for the Treatment of Musculoskeletal Diseases: Production Process Validation and Batch Release Test for Clinical Use
inferred← citeshttps://doi.org/10.3390/polym15092219openalex-snapshot
Design and Application of Hybrid Polymer-Protein Systems in Cancer Therapy
inferred← citeshttps://doi.org/10.3390/su13169204openalex-snapshot
Sustainable Development of Apple Snack Formulated with Blueberry Juice and Trehalose
inferred← citeshttps://doi.org/10.3390/vetsci13080787openalex-snapshot
Stallion Sperm Lyophilisation: Effect of Source of Sperm and Reproductive Season
inferred← citeshttps://doi.org/10.35537/10915/143541openalex-snapshot
Estructura electrónica y dinámica molecular de los disacáridos trehalosa, maltosa y sacarosa
inferred← citeshttps://doi.org/10.4103/1673-5374.360164openalex-snapshot
Profiling neuroprotective potential of trehalose in animal models of neurodegenerative diseases: a systematic review
inferred← citeshttps://doi.org/10.4103/atmr.atmr_112_25openalex-snapshot
Natural Stabiliser-enhanced Loop-mediated Isothermal Amplification Assay for Field-deployable Detection of Antibiotic-resistant Pasteurella multocida in Saudi Arabian Veterinary Settings
inferred← citeshttps://doi.org/10.4155/bio-2020-0299openalex-snapshot
Increasing Robustness, Reliability and Storage Stability of Critical Reagents by Freeze-Drying
inferred← citeshttps://doi.org/10.52547/iau.32.2.111openalex-snapshot
A review of methods to increase the stability of recombinant pharmaceutical proteins during the production and storage process
inferred← citeshttps://doi.org/10.6084/m9.figshare.14966207openalex-snapshot
Additional file 1 of Chemical-free recovery of crude protein from livestock manure digestate solid by thermal hydrolysis
inferred← citeshttps://doi.org/10.61474/ncs.2023.00012openalex-snapshot
A Network Pharmacology Approach to Assess the Comparative Pharmacodynamics of Pharmaceutical Excipient Trehalose in Human, Mouse, and Rat
inferred← citeshttps://doi.org/10.64898/2026.07.06.736713openalex-snapshot
Serum-free media development and validation for cultivation of C2C12 immortalised murine myosatellite cell line for cultivated meat
inferred← citeshttps://doi.org/10.70675/09800ecczf47cz429ezae7ez5de177b74c8copenalex-snapshot
Spray-drying of biopharmaceutical drug products
inferred← citeshttps://doi.org/10.7554/elife.38337openalex-snapshot
Synergy between the small intrinsically disordered protein Hsp12 and trehalose sustain viability after severe desiccation
inferred← citeshttps://doi.org/10.7868/s0869565217330222openalex-snapshot
ВЛИЯНИЕ ТРЕГАЛОЗЫ НА ВЫСОКОТЕМПЕРАТУРНУЮ УСТОЙЧИВОСТЬ ФОТОСИНТЕТИЧЕСКИХ РЕАКЦИОННЫХ ЦЕНТРОВ, "Доклады Академии наук"
Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.