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Potential of Three Ethnomedicinal Plants as Antisickling Agents
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/ajh.1098openalex-snapshot
In vitro exposure to hydroxyurea reduces sickle red blood cell deformability
inferredcites →https://doi.org/10.1002/ajh.2830320206openalex-snapshot
Effect of hydroxyurea on the rheological properties of sickle erythrocytes in vivo
inferredcites →https://doi.org/10.1002/cbdv.200890165openalex-snapshot
Pyridyl Derivatives of Benzaldehyde as Potential Antisickling Agents
inferredcites →https://doi.org/10.1002/jsfa.2740380309openalex-snapshot
Measurement of protein in tannin‐protein precipitates using ninhydrin
inferredcites →https://doi.org/10.1002/ptr.1323openalex-snapshot
Anti‐sickling potential of a Nigerian herbal formula (ajawaron HF) and the major plant component (Cissus populnea L. CPK)
inferredcites →https://doi.org/10.1007/978-1-4615-3030-5openalex-snapshot
The Use of Resealed Erythrocytes as Carriers and Bioreactors
inferredcites →https://doi.org/10.1007/978-1-4615-3030-5_1openalex-snapshot
On Red Blood Cells, Hemolysis and Resealed Ghosts
inferredcites →https://doi.org/10.1007/bf01048331openalex-snapshot
The use of hydrophobic synthetic glycosides as acceptors in glycosyltransferase assays
inferredcites →https://doi.org/10.1016/0022-2836(85)90175-5openalex-snapshot
Kinetics of sickle hemoglobin polymerization
inferredcites →https://doi.org/10.1016/0143-4160(85)90009-0openalex-snapshot
Sickle-cell membrane-bound (Ca2+ + Mg2+)-ATPase: Activation by 3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-6-butyric acid, a novel antisickling agent
inferredcites →https://doi.org/10.1016/j.phymed.2008.10.013openalex-snapshot
Antisickling properties of divanilloylquinic acids isolated from Fagara zanthoxyloides Lam. (Rutaceae)
inferredcites →https://doi.org/10.1016/s0006-3495(02)75404-0openalex-snapshot
Heterogeneous Nucleation and Crowding in Sickle Hemoglobin: An Analytic Approach
inferredcites →https://doi.org/10.1016/s0065-3233(08)60287-9openalex-snapshot
Sickle Cell Hemoglobin Polymerization
inferredcites →https://doi.org/10.1016/s0378-4347(00)80384-9openalex-snapshot
An update on electrophoretic and chromatographic methods in the diagnosis of hemoglobinopathies
inferredcites →https://doi.org/10.1038/180326a0openalex-snapshot
Gene Mutations in Human Hæmoglobin: the Chemical Difference Between Normal and Sickle Cell Hæmoglobin
inferredcites →https://doi.org/10.1042/bj0650212openalex-snapshot
Properties of sickle-cell haemoglobin
inferredcites →https://doi.org/10.1046/j.1365-2141.2002.03593.xopenalex-snapshot
In vitro effects of NIPRISAN (Nix‐0699): a naturally occurring, potent antisickling agent
inferredcites →https://doi.org/10.1046/j.1365-2141.2003.03849.xopenalex-snapshot
The role of hydroxyurea in sickle cell disease
inferredcites →https://doi.org/10.1046/j.1365-3059.1999.00318.xopenalex-snapshot
Phytochemical Methods. A Guide to Modern Techniques of Plant Analysis.
inferredcites →https://doi.org/10.1055/s-0028-1097271openalex-snapshot
Antimicrobial Alkaloids from a Nigerian Chewing Stick (Fagara zanthoxyloides)
inferredcites →https://doi.org/10.1055/s-2006-960880openalex-snapshot
Phenylalanine is the Predominant Antisickling Agent inCajanus cajanSeed Extract
inferredcites →https://doi.org/10.1055/s-2007-969576openalex-snapshot
The Reversion of Sickled Cells byCajanus cajan
inferredcites →https://doi.org/10.1056/nejm199004123221504openalex-snapshot
Hematologic Responses of Patients with Sickle Cell Disease to Treatment with Hydroxyurea
inferredcites →https://doi.org/10.1056/nejm199505183322001openalex-snapshot
Effect of Hydroxyurea on the Frequency of Painful Crises in Sickle Cell Anemia
inferredcites →https://doi.org/10.1056/nejmct0708272openalex-snapshot
Hydroxyurea for the Treatment of Sickle Cell Anemia
inferredcites →https://doi.org/10.1073/pnas.74.12.5499openalex-snapshot
Alternative aspirins as antisickling agents: acetyl-3,5-dibromosalicylic acid.
inferredcites →https://doi.org/10.1073/pnas.76.2.670openalex-snapshot
Structural bases of the inhibitory effects of hemoglobin F and hemoglobin A2 on the polymerization of hemoglobin S.
inferredcites →https://doi.org/10.1111/j.1365-2141.2004.05332.xopenalex-snapshot
5‐hydroxymethyl‐2‐furfural modifies intracellular sickle haemoglobin and inhibits sickling of red blood cells†,‡
inferredcites →https://doi.org/10.1111/j.1749-6632.1989.tb24152.xopenalex-snapshot
Intracellular Polymerization
inferredcites →https://doi.org/10.1126/science.7539154openalex-snapshot
The Biophysics of Sickle Cell Hydroxyurea Therapy
inferredcites →https://doi.org/10.1152/ajpheart.01068.2007openalex-snapshot
Hydroxyurea attenuates activated neutrophil-mediated sickle erythrocyte membrane phosphatidylserine exposure and adhesion to pulmonary vascular endothelium
inferredcites →https://doi.org/10.1155/2016/2046535openalex-snapshot
Sickle-Cell Disease Healthcare Cost in Africa: Experience of the Congo
inferredcites →https://doi.org/10.1172/jci104636openalex-snapshot
STUDIES ON THE OSMOTIC FRAGILITY OF INCUBATED NORMAL AND ABNORMAL ERYTHROCYTES*
inferredcites →https://doi.org/10.1172/jci105775openalex-snapshot
Bile salts and cholesterol in the pathogenesis of target cells in obstructive jaundice
inferredcites →https://doi.org/10.1172/jci16672openalex-snapshot
Hydroxyurea induces fetal hemoglobin by the nitric oxide–dependent activation of soluble guanylyl cyclase
inferredcites →https://doi.org/10.1182/blood-2007-05-088732openalex-snapshot
Hydroxyurea nitrosylates and activates soluble guanylyl cyclase in human erythroid cells
inferredcites →https://doi.org/10.1182/blood-2014-08-435768openalex-snapshot
Update on the use of hydroxyurea therapy in sickle cell disease
inferredcites →https://doi.org/10.1182/blood.v70.5.1245.1245openalex-snapshot
Hemoglobin S gelation and sickle cell disease
inferredcites →https://doi.org/10.1182/blood.v77.6.1334.1334openalex-snapshot
Vanillin, a potential agent for the treatment of sickle cell anemia
inferredcites →https://doi.org/10.1182/blood.v83.2.553.553openalex-snapshot
Hydroxyurea affects cell morphology, cation transport, and red blood cell adhesion in cultured vascular endothelial cells
inferredcites →https://doi.org/10.1182/blood.v94.5.1555openalex-snapshot
Sickle Cell Acute Chest Syndrome: Pathogenesis and Rationale for Treatment
inferredcites →https://doi.org/10.1186/1472-6882-13-162openalex-snapshot
The in vitro antisickling and antioxidant effects of aqueous extracts Zanthoxyllum heitzii on sickle cell disorder
inferredcites →https://doi.org/10.1631/jzus.2007.b0153openalex-snapshot
Adjuvant effects of saponins on animal immune responses
inferredcites →https://doi.org/10.3923/jms.2011.129.137openalex-snapshot
Anti Sickle Erythrocytes Haemolysis Properties and Inhibitory Effect of Anthocyanins Extracts of Trema orientalis (Ulmaceae) on the Aggregation of Human Deoxyhemoglobin S in vitro
inferredcites →https://doi.org/10.4065/83.3.320openalex-snapshot
The Sickle Cell Crisis: A Dilemma in Pain Relief
inferredcites →https://doi.org/10.4103/0973-7847.112849openalex-snapshot
Search for antisickling agents from plants
inferredcites →https://doi.org/10.5897/ajb08.758openalex-snapshot
The potential of Terminalia catappa (Almond) and Hyphaene thebaica (Dum palm) fruits as raw materials for livestock feed
inferredcites →https://doi.org/10.5897/ajb09.273openalex-snapshot
Erythrocyte osmotic fragility of pigs administered ascorbic acid and transported by road for short-term duration during the harmattan season
inferredcites →https://doi.org/10.5897/ajb2006.000-5089openalex-snapshot
Antisickling agent in an extract of unripe pawpaw (Carica papaya): Is it real?
inferredcites →https://doi.org/10.5897/jmpr.9000243openalex-snapshot
Antisickling and toxicological profiles of leaf and stem of Parquetina nigrescens L.
inferredcites →https://doi.org/10.7326/0003-4819-14-8-1452_1openalex-snapshot
Fundamentals of Biochemistry.
inferredcites →https://doi.org/10.9734/bjmmr/2015/14608openalex-snapshot
Anti-Sickling and Membrane Stabilizing Effects of Carica papaya Leaf Extract
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.3988610openalex-extracted
Acute Toxicity Profiles and Malaria Chemoprotective Properties of Methanol Extract of Zanthoxylum Zanthoxyloides Root Bark and its Fractions
inferred← citeshttps://doi.org/10.1007/978-3-031-80866-1_35-1openalex-snapshot
Computational and Molecular Modelling Aspects of Algal Research: Therapeutic Importance of Algae—Evidence from Molecular Docking and Molecular Dynamics Studies
inferred← citeshttps://doi.org/10.1007/s00044-025-03445-xopenalex-snapshot
Nutraceuticals interventions in the management of sickle cell anemia: bridging nutritional support and therapeutic strategies
inferred← citeshttps://doi.org/10.1007/s00580-025-03677-8openalex-snapshot
Anacardium occidentale L. nuts: an anti-sickling agent for sickle cell beta-thalassemia
inferred← citeshttps://doi.org/10.1007/s40199-020-00348-7openalex-snapshot
Therapeutic application of Carica papaya leaf extract in the management of human diseases
inferred← citeshttps://doi.org/10.1007/s43450-024-00535-6openalex-snapshot
The Use of Natural Products in the Treatment of Sickle Cell Disease
inferred← citeshttps://doi.org/10.1016/b978-0-12-812491-8.00048-5openalex-snapshot
Papaya (Carica papaya L., Pawpaw)
inferred← citeshttps://doi.org/10.1016/j.arabjc.2021.103539openalex-snapshot
Anti sickling potential and chemical profiling of traditionally used Woodfordia fruticosa (L.) Kurz leaves
inferred← citeshttps://doi.org/10.1016/j.bcmd.2025.102956openalex-snapshot
Anti-sickling efficacy and safety of Sailin-HbS, an indigenous Ayurvedic formulation
inferred← citeshttps://doi.org/10.1016/j.bglo.2026.100072openalex-snapshot
Sickle cell disease: then and now
inferred← citeshttps://doi.org/10.1016/j.hermed.2020.100398openalex-snapshot
Promising anti-sickling and fetal hemoglobin inducing effects of Boerhavia diffusa root extract on sickle cell erythrocytes
inferred← citeshttps://doi.org/10.1016/j.jep.2020.113508openalex-snapshot
Quail (Coturnix japonica) egg attenuated 2-butoxyethanol-induced enzymatic dysregulation, disseminated thrombosis and hemolytic impairment in female wistar rats
inferred← citeshttps://doi.org/10.1016/j.jep.2024.118280openalex-snapshot
Evaluation of anti-sickling effects of two varieties of Cajanus cajan (L.) Huth on sickle cell beta thalassemia
inferred← citeshttps://doi.org/10.1016/j.phymed.2024.155936openalex-snapshot
Targeted therapeutic management based on phytoconstituents for sickle cell anemia focusing on molecular mechanisms: Current trends and future perspectives
inferred← citeshttps://doi.org/10.1016/j.prenap.2024.100056openalex-snapshot
Anti-sickling effect of Vigna subterranean (L.) Verdc on sickle cell beta thalassemia
inferred← citeshttps://doi.org/10.1016/j.prmcm.2023.100339openalex-snapshot
Review on pharmacology activities of Justicia Gendarussa Burm F.
inferred← citeshttps://doi.org/10.1016/j.sajb.2025.12.027openalex-snapshot
Biological screening of medicinal plants used by SCD patients in the eastern part of Madagascar for their anti-sickling and analgesic activities
inferred← citeshttps://doi.org/10.1016/j.sciaf.2026.e03291openalex-snapshot
Ethnopharmacological survey of medicinal plants traditionally used to manage sickle cell disease in Mwanza and Mara Regions, Tanzania
inferred← citeshttps://doi.org/10.1038/s41598-024-75078-wopenalex-snapshot
Computational screening of phytochemicals present in some Nigerian medicinal plants against sickle cell disease
inferred← citeshttps://doi.org/10.1039/c7ra12079fopenalex-snapshot
Privileged substructures for anti-sickling activity via cheminformatic analysis
inferred← citeshttps://doi.org/10.1039/d3ra03312kopenalex-snapshot
Comparative antisickling and antioxidant activities of Pseudobombax ellipticum cultivars in relation to their metabolite profiling using LC/MS
inferred← citeshttps://doi.org/10.1080/07391102.2018.1557557openalex-snapshot
Alizarin interaction with sickle hemoglobin: elucidation of their anti-sickling properties by multi-spectroscopic and molecular modeling techniques
inferred← citeshttps://doi.org/10.1080/07391102.2019.1645735openalex-snapshot
Potential of isoquercitrin as antisickling agent: a multi-spectroscopic, thermophoresis and molecular modeling approach
inferred← citeshttps://doi.org/10.1080/07391102.2020.1828171openalex-snapshot
Biochemical investigation of the upstream anti-sickling mechanisms of soursop (Annona muricata): 15-acetyl guanacone as an inhibitor of deoxyhaemoglobin polymerisation
inferred← citeshttps://doi.org/10.1080/07391102.2020.1852967openalex-snapshot
Repurposing of genistein as anti-sickling agent: elucidation by multi spectroscopic, thermophoresis, and molecular modeling techniques
inferred← citeshttps://doi.org/10.1080/13880209.2018.1501585openalex-snapshot
Adaptation of a microbead assay for the easy evaluation of traditional anti-sickling medicines: application to DREPANOSTAT and FACA
inferred← citeshttps://doi.org/10.1080/14786419.2022.2158330openalex-snapshot
In-vitro anti-sickling potential of baicalin and naringenin isolated from Oroxylum indicum and Citrus aurantium on human sickle red blood cells
inferred← citeshttps://doi.org/10.1093/jpp/rgaa019openalex-snapshot
Zanthoxylum zanthoxyloides inhibits lipopolysaccharide- and synthetic hemozoin-induced neuroinflammation in BV-2 microglia: roles of NF-κB transcription factor and NLRP3 inflammasome activation
inferred← citeshttps://doi.org/10.1101/2021.07.25.453693openalex-snapshot
Hoslundia opposita and other Nigerian plants inhibit sickle hemoglobin polymerization and prevent erythrocyte sickling: a virtual screening-guided identification of bioactive plants
inferred← citeshttps://doi.org/10.1155/2022/5098428openalex-snapshot
Ethnopharmacological Study of the Medicinal Plants Used in the Treatment of Sickle Cell Anemia in the West Region of Cameroon
inferred← citeshttps://doi.org/10.1155/anem/9936958openalex-snapshot
Systematic Review on Plant‐Based Therapies for the Management of Sickle Cell Anaemia
inferred← citeshttps://doi.org/10.1177/15347354211068417openalex-snapshot
A Case Study Using Papaya Leaf Extract to Reverse Chemotherapy-Induced Thrombocytopenia in a GBM Patient
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Scientific Validation of South African Aphrodisiac Plants for Erectile Dysfunction: An Exploratory Review
inferred← citeshttps://doi.org/10.1186/s12906-025-04943-6openalex-snapshot
In vitro study of anti-sickling effects of aqueous extracts of Garcinia kola (seeds), Zingiber officinale (rhizomes) and Allium sativum(bulbs) on sodium metabisulphite-treated HBSS erythrocytes
inferred← citeshttps://doi.org/10.1186/s42269-020-00392-yopenalex-snapshot
Polymerization of deoxygenated sickle hemoglobin in the presence of fractionated leaf extracts of Anacardium occidentale, Psidium guajava, and Terminalia catappa
inferred← citeshttps://doi.org/10.1186/s43088-019-0030-zopenalex-snapshot
Phytocomponents from Anacardium occidentale, Psidium guajava, and Terminalia catappa altered membrane osmotic stability of sickle erythrocytes
inferred← citeshttps://doi.org/10.1515/arls-2018-0019openalex-snapshot
Chemical Composition, Antioxidant and Antibacterial Properties of Chloroform Fraction of Platycerium Bifurcatum
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Antimalarial plants with potential male-factor antifertility properties
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Nutrition in sickle cell disease: recent insights
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Carica papaya: Potential Implications in Human Health
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Traditional Drugs Originating from Selected Medicinal Plants: An Intervention for Anaemia
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An In vitro investigation of Lactobacillus plantarum F4 Strain’s Anti-sickling and Fetal Hemoglobin Inducing Effects on Sickled Erythrocytes
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GC-MS aided In silico molecular docking studies on the anti-sickling properties of Zanthoxylum zanthoxyloides (Lam.) Zepern. & Timler stem bark
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Phytochemical investigation and antisickling properties of a Poly-herbal formula on the HBSS Red Blood Cells
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Medicinal plants for management and alternative therapy of common ailments in Dutsin-Ma (Katsina State) in Nigeria
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Sickle hemoglobin polymerization and antisickling medicinal plants
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Zanthoxylum Species: A Review of Traditional Uses, Phytochemistry and Pharmacology in Relation to Cancer, Infectious Diseases and Sickle Cell Anemia
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Six Express Sequence Tag–Simple Sequence Repeat Primers Reveal Genetic Diversity in the Cultivars of Three Zanthoxylum Species
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Carica papaya L.: A Tropical Fruit with Benefits beyond the Tropics
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Zanthoxylum Species: A Comprehensive Review of Traditional Uses, Phytochemistry, Pharmacological and Nutraceutical Applications
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Unveiling the Anti-Cholera and Active Diabetic Renoprotective Compounds of Maqian Essential Oil: A Computational and Molecular Dynamics Study
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Evidence-Based Management of Sickle Cell Disease: Ethnobotanical Survey and Laboratory Validation of Traditional Herbal Recipes
inferred← citeshttps://doi.org/10.4103/ejh.ejh_33_18openalex-snapshot
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DOMINANCE OF HERBAL MEDICINES IN TREATING SICKEL CELL ANEMIA
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Preliminary Evaluation of the Anti-sickling and Polymerization Time Rate of Aqueous Extracts of Beta Vulgaris (Beetroot) on Sickle Cell Disorder (In-vitro model)
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Preliminary study to identify anti-sickle cell plants in Nigers traditional pharmacopoeia and their phytochemicals
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AN OVERVIEW FOR PHYTOCHEMICAL ACTIVITIES OF CARICA PAPAYA FRUIT
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