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Glucan Particles Are a Powerful Adjuvant for the HBsAg, Favoring Antiviral Immunity

https://doi.org/10.1021/acs.molpharmaceut.8b01322

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What this work says

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The Spleen in Local and Systemic Regulation of Immunity

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Specific immune response to HBsAg is enhanced by β-glucan oligosaccharide containing an α-(1→3)-linked bond and biased towards M2/Th2

inferredcites →https://doi.org/10.1016/j.intimp.2008.08.013openalex-snapshot

Alginate coated chitosan nanoparticles are an effective subcutaneous adjuvant for hepatitis B surface antigen

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Fungal cell wall agents suppress the innate inflammatory cytokine responses of human peripheral blood mononuclear cells challenged with lipopolysaccharide in vitro

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Activation of the NLRP3 inflammasome is not a feature of all particulate vaccine adjuvants

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Activation of the innate immune receptor Dectin-1 upon formation of a ‘phagocytic synapse’

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What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Glucans

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Yeast-derived nanocarriers enable binary reprogramming macrophages for cancer immunotherapy

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Lycium barbarum polysaccharide promotes the immunoprotective effects of recombinant Lactobacillus plantarum vaccine expressing Trichinella spiralis cathepsin F-like protease 1 gene

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