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Extra-Large Pore Mesoporous Silica Nanoparticles for Directing in Vivo M2 Macrophage Polarization by Delivering IL-4

https://doi.org/10.1021/acs.nanolett.6b04130

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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inferred← citeshttps://doi.org/10.1016/j.cej.2018.11.156openalex-snapshot

Mesoporous silica nanoparticles: Synthesis, pharmaceutical applications, biodistribution, and biosafety assessment

inferred← citeshttps://doi.org/10.1016/j.cej.2021.134145openalex-snapshot

Recent advance in nanomaterials for cancer immunotherapy

inferred← citeshttps://doi.org/10.1016/j.cej.2022.138782openalex-snapshot

A robust ROS generation nanoplatform combating periodontitis via sonodynamic/chemodynamic combination therapy

inferred← citeshttps://doi.org/10.1016/j.cej.2023.143989openalex-snapshot

Ginsenoside Rg5 nanomedicine composited hydrogel with metabolic regulation and immunomodulation properties for tunneling diabetic wounds therapy

inferred← citeshttps://doi.org/10.1016/j.ceramint.2023.03.181openalex-snapshot

A boric acid-assisted hydrothermal process for preparation of mesoporous silica nanoparticles with ultra-large mesopores and tunable particle sizes

inferred← citeshttps://doi.org/10.1016/j.colsurfb.2024.113920openalex-snapshot

Size effect of mesoporous silica nanoparticles on regulating the immune effect of oral influenza split vaccine

inferred← citeshttps://doi.org/10.1016/j.colsurfb.2025.115392openalex-snapshot

Hydrogel composite nanomaterials for diabetic wound treatment

inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2025.142254openalex-snapshot

Longan-inspired chitosan-pectin core-shell hydrogel beads for oral delivery of biodrugs to enhance osteoporosis therapy

inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2025.149869openalex-snapshot

Immunomodulatory mesoporous bioactive glass/interleukin-4 nanocomplex promotes bone regeneration

inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2026.154046openalex-snapshot

Quenching and awakening: A demethylated lignin composite enabling dual antioxidant pathways for extending the preservation period of blueberry

inferred← citeshttps://doi.org/10.1016/j.intimp.2026.117116openalex-snapshot

Diabetic cardiomyopathy: Target immune cell from mechanism to treatment

inferred← citeshttps://doi.org/10.1016/j.jcis.2020.12.117openalex-snapshot

Gold nanoparticle-guarded large-pore mesoporous silica nanocomposites for delivery and controlled release of cytochrome c

inferred← citeshttps://doi.org/10.1016/j.jclepro.2021.125922openalex-snapshot

Dendritic fibrous nanosilica loaded chitosan for improving water vapor permeability and antibacterial properties of waterborne polyurethane acrylate membranes

inferred← citeshttps://doi.org/10.1016/j.jconrel.2021.07.010openalex-snapshot

Targeted-lung delivery of dexamethasone using gated mesoporous silica nanoparticles. A new therapeutic approach for acute lung injury treatment

inferred← citeshttps://doi.org/10.1016/j.jconrel.2022.09.015openalex-snapshot

Lymph node-targeting nanovaccines for cancer immunotherapy

inferred← citeshttps://doi.org/10.1016/j.jddst.2020.101906openalex-snapshot

Mesoporous silica nanoparticles as delivery carriers: An overview of drug loading techniques

inferred← citeshttps://doi.org/10.1016/j.jddst.2023.104192openalex-snapshot

Immunoregulatory effects on RAW264.7 cells and subacute oral toxicity of ultra-large pore mesoporous silica nanoparticles loading Lycium barbarum polysaccharides

inferred← citeshttps://doi.org/10.1016/j.jddst.2025.107021openalex-snapshot

Mesoporous silica nanoparticles in skin cancer therapy: Multifaceted approaches in drug delivery

inferred← citeshttps://doi.org/10.1016/j.jinorgbio.2021.111454openalex-snapshot

Design and application of nanoparticles as vaccine adjuvants against human corona virus infection

inferred← citeshttps://doi.org/10.1016/j.matchemphys.2020.123335openalex-snapshot

Hierarchically porous zirconium dioxide dual-templated by acacia mangium tannin extract and an amphiphilic triblock copolymer

inferred← citeshttps://doi.org/10.1016/j.micromeso.2019.06.005openalex-snapshot

Experimental evidences on the role of silica nanoparticles surface morphology on the loading, release and activity of three proteins

inferred← citeshttps://doi.org/10.1016/j.micromeso.2023.112730openalex-snapshot

Facile and controllable preparation of mesoporous silica nanoparticles with ultra-large mesopores enabled by an ammonium chloride–assisted hydrothermal process

inferred← citeshttps://doi.org/10.1016/j.molimm.2021.08.003openalex-snapshot

Modulating immune microenvironment during bone repair using biomaterials: Focusing on the role of macrophages

inferred← citeshttps://doi.org/10.1016/j.msec.2019.109833openalex-snapshot

Strontium released bi-lineage scaffolds with immunomodulatory properties induce a pro-regenerative environment for osteochondral regeneration

inferred← citeshttps://doi.org/10.1016/j.msec.2021.112621openalex-snapshot

Hollow mesoporous silica nanoparticles: Effective silica etching using tri-di- and mono-valent cations

inferred← citeshttps://doi.org/10.1016/j.mtbio.2022.100472openalex-snapshot

Mesoporous silicas in materials engineering: Nanodevices for bionanotechnologies

inferred← citeshttps://doi.org/10.1016/j.mtbio.2024.101335openalex-snapshot

Bioactive hydrogel synergizes neuroprotection, macrophage polarization, and angiogenesis to improve repair of traumatic brain injury

inferred← citeshttps://doi.org/10.1016/j.mtchem.2022.101144openalex-snapshot

Nonordered dendritic mesoporous silica nanoparticles as promising platforms for advanced methods of diagnosis and therapies

inferred← citeshttps://doi.org/10.1016/j.nantod.2022.101554openalex-snapshot

Nanomaterials-based imaging diagnosis and therapy of cardiovascular diseases

inferred← citeshttps://doi.org/10.1016/j.omtn.2022.11.018openalex-snapshot

Liposome-mediated small RNA delivery to convert the macrophage polarity: A novel therapeutic approach to treat inflammatory uterine disease

inferred← citeshttps://doi.org/10.1016/j.rinma.2026.100984openalex-snapshot

Advances of nanoparticles in bone regeneration: Synthesis, challenges, and clinical impacts – A review

inferred← citeshttps://doi.org/10.1016/j.seminoncol.2025.152433openalex-snapshot

Submicron silica particles drives prostate cancer aggressiveness via lipid-metabolic reprogramming

inferred← citeshttps://doi.org/10.1016/j.smim.2017.08.013openalex-snapshot

Nanoparticles and innate immunity: new perspectives on host defence

inferred← citeshttps://doi.org/10.1016/j.trac.2019.115759openalex-snapshot

Aptamer-conjugated mesoporous silica nanoparticles for simultaneous imaging and therapy of cancer

inferred← citeshttps://doi.org/10.1021/acs.chemmater.1c04397openalex-snapshot

Template-Assisted Antibody Assembly: A Versatile Approach for Engineering Functional Antibody Nanoparticles

inferred← citeshttps://doi.org/10.1021/acs.chemmater.2c03234openalex-snapshot

Adhesive Composite Hydrogel Patch for Sustained Transdermal Drug Delivery To Treat Atopic Dermatitis

inferred← citeshttps://doi.org/10.1021/acs.inorgchem.1c03818openalex-snapshot

Best Practices in the Characterization of MOF@MSN Composites

inferred← citeshttps://doi.org/10.1021/acs.langmuir.7b03310openalex-snapshot

Conserved Activity of Reassociated Homotetrameric Protein Subunits Released from Mesoporous Silica Nanoparticles

inferred← citeshttps://doi.org/10.1021/acs.molpharmaceut.0c01253openalex-snapshot

A Peptide-Based Small RNA Delivery System to Suppress Tumor Growth by Remodeling the Tumor Microenvironment

inferred← citeshttps://doi.org/10.1021/acs.molpharmaceut.5c00501openalex-snapshot

A Critical View on the Biocompatibility of Silica Nanoparticles and Liposomes as Drug Delivery Systems

inferred← citeshttps://doi.org/10.1021/acs.nanolett.0c02576openalex-snapshot

Controlled Nutrient Delivery to Pancreatic Islets Using Polydopamine-Coated Mesoporous Silica Nanoparticles

inferred← citeshttps://doi.org/10.1021/acs.nanolett.7b03405openalex-snapshot

Remote Manipulation of Ligand Nano-Oscillations Regulates Adhesion and Polarization of Macrophages in Vivo

inferred← citeshttps://doi.org/10.1021/acs.nanolett.8b00689openalex-snapshot

Repolarization of Tumor-Associated Macrophages in a Genetically Engineered Nonsmall Cell Lung Cancer Model by Intraperitoneal Administration of Hyaluronic Acid-Based Nanoparticles Encapsulating MicroRNA-125b

inferred← citeshttps://doi.org/10.1021/acs.nanolett.8b05150openalex-snapshot

Anisotropic Ligand Nanogeometry Modulates the Adhesion and Polarization State of Macrophages

inferred← citeshttps://doi.org/10.1021/acsabm.1c00704openalex-snapshot

Bioinspired Silicification of mRNA-Loaded Polyion Complexes for Macrophage-Targeted mRNA Delivery

inferred← citeshttps://doi.org/10.1021/acsabm.3c00940openalex-snapshot

Engineered Nanomaterials for Immunomodulation: A Review

inferred← citeshttps://doi.org/10.1021/acsabm.9b00483openalex-snapshot

Mesoporous Silica Nanoparticles Doped with Gold Nanoparticles for Combined Cancer Immunotherapy and Photothermal Therapy

inferred← citeshttps://doi.org/10.1021/acsami.0c00596openalex-snapshot

Design of Dendritic Large-Pore Mesoporous Silica Nanoparticles with Controlled Structure and Formation Mechanism in Dual-Templating Strategy

inferred← citeshttps://doi.org/10.1021/acsami.0c09484openalex-snapshot

Hollow Mesoporous Silica Nanoparticles with Extra-Large Mesopores for Enhanced Cancer Vaccine

inferred← citeshttps://doi.org/10.1021/acsami.0c17863openalex-snapshot

A Versatile Interfacial Coassembly Method for Fabrication of Tunable Silica Shells with Radially Aligned Dual Mesopores on Diverse Magnetic Core Nanoparticles

inferred← citeshttps://doi.org/10.1021/acsami.0c17923openalex-snapshot

Multimode Imaging-Guided Photothermal/Chemodynamic Synergistic Therapy Nanoagent with a Tumor Microenvironment Responded Effect

inferred← citeshttps://doi.org/10.1021/acsami.4c07106openalex-snapshot

High Cellular Internalization of Virus-Like Mesoporous Silica Nanoparticles Enhances Adaptive Antigen-Specific Immune Responses against Cancer

inferred← citeshttps://doi.org/10.1021/acsami.7b15678openalex-snapshot

Bacteria-Targeting Nanoparticles with Microenvironment-Responsive Antibiotic Release To Eliminate Intracellular Staphylococcus aureus and Associated Infection

inferred← citeshttps://doi.org/10.1021/acsami.8b09069openalex-snapshot

Facile Strategy Enabling Both High Loading and High Release Amounts of the Water-Insoluble Drug Clofazimine Using Mesoporous Silica Nanoparticles

inferred← citeshttps://doi.org/10.1021/acsanm.0c03424openalex-snapshot

Stimulation and Suppression of the Innate Immune System through Nanotechnology

inferred← citeshttps://doi.org/10.1021/acsanm.1c02209openalex-snapshot

Self-Contained Nanocapsules Carrying Anticancer Peptides for Magnetically Activated and Enzyme-Cleaved Drug Delivery

inferred← citeshttps://doi.org/10.1021/acsanm.3c01210openalex-snapshot

Water-Dispersible Fluorescent Silicon Nanoparticles That Modulate Inflammatory Response in Macrophages

inferred← citeshttps://doi.org/10.1021/acsbiomaterials.0c01011openalex-snapshot

Delivery of Interleukin 4 from a Titanium Substrate Coated with Graphene Oxide for Enhanced Osseointegration by Regulating Macrophage Polarization

inferred← citeshttps://doi.org/10.1021/acsbiomaterials.0c01287openalex-snapshot

Biomaterials-Based Opportunities to Engineer the Pulmonary Host Immune Response in COVID-19

inferred← citeshttps://doi.org/10.1021/acsbiomaterials.1c00882openalex-snapshot

Evaluation of Interleukin-4-Loaded Sodium Alginate–Chitosan Microspheres for Their Support of Microvascularization in Engineered Tissues

inferred← citeshttps://doi.org/10.1021/acsbiomaterials.1c00899openalex-snapshot

Modulating Osteoimmune Responses by Mesoporous Silica Nanoparticles

inferred← citeshttps://doi.org/10.1021/acsbiomaterials.1c00946openalex-snapshot

Alternative Activation of Macrophages through Interleukin-13-Loaded Extra-Large-Pore Mesoporous Silica Nanoparticles Suppresses Experimental Autoimmune Encephalomyelitis

inferred← citeshttps://doi.org/10.1021/acsbiomaterials.3c00080openalex-snapshot

Remote Activation of M2 Macrophage Polarization via Magneto-Mechanical Stimulation To Promote Osteointegration

inferred← citeshttps://doi.org/10.1021/acscentsci.8b00035openalex-snapshot

Extra-Large Pore Mesoporous Silica Nanoparticles Enabling Co-Delivery of High Amounts of Protein Antigen and Toll-like Receptor 9 Agonist for Enhanced Cancer Vaccine Efficacy

inferred← citeshttps://doi.org/10.1021/acsnano.0c05392openalex-snapshot

An Intelligent Biomimetic Nanoplatform for Holistic Treatment of Metastatic Triple-Negative Breast Cancer via Photothermal Ablation and Immune Remodeling

inferred← citeshttps://doi.org/10.1021/acsnano.1c10635openalex-snapshot

Nanotechnology Tools Enabling Biological Discovery

inferred← citeshttps://doi.org/10.1021/acsnano.3c06115openalex-snapshot

A Bionic Yeast Tumor Vaccine Using the Co-Loading Strategy to Prevent Post-Operative Tumor Recurrence

inferred← citeshttps://doi.org/10.1021/acsnano.5c13784openalex-snapshot

Engineered 3D-Lattice Microneedle Array Patches for Enhanced Nanovaccine Delivery to Dendritic Cells in Cancer Immunotherapy

inferred← citeshttps://doi.org/10.1021/acsnano.8b02226openalex-snapshot

Magnetic Manipulation of Reversible Nanocaging Controls In Vivo Adhesion and Polarization of Macrophages

inferred← citeshttps://doi.org/10.1021/acsnano.9b06691openalex-snapshot

Positron Emission Tomography-Guided Photodynamic Therapy with Biodegradable Mesoporous Silica Nanoparticles for Personalized Cancer Immunotherapy

inferred← citeshttps://doi.org/10.1021/acsomega.5c10721openalex-snapshot

Dual-Function Sol–Gel Antibacterial Materials with Biphasic Octenidine Release for Decontamination and Long-Term Protection

inferred← citeshttps://doi.org/10.1021/acsomega.8b03182openalex-snapshot

Targeted Reinforcement of Macrophage Reprogramming Toward M2 Polarization by IL-4-Loaded Hyaluronic Acid Particles

inferred← citeshttps://doi.org/10.1021/jacs.3c09334openalex-snapshot

Self-Assembly of Epitope-Tagged Proteins and Antibodies for Delivering Biologics to Antigen Presenting Cells

inferred← citeshttps://doi.org/10.1038/s41467-019-09733-6openalex-snapshot

Immunoregulation of macrophages by dynamic ligand presentation via ligand–cation coordination

inferred← citeshttps://doi.org/10.1038/s41467-022-35263-9openalex-snapshot

Immunosuppressive biomaterial-based therapeutic vaccine to treat multiple sclerosis via re-establishing immune tolerance

inferred← citeshttps://doi.org/10.1038/s41578-020-0230-0openalex-snapshot

Synthetic amorphous silica nanoparticles: toxicity, biomedical and environmental implications

inferred← citeshttps://doi.org/10.1038/s41578-022-00426-zopenalex-snapshot

Design of therapeutic biomaterials to control inflammation

inferred← citeshttps://doi.org/10.1038/s41578-024-00767-xopenalex-snapshot

Design of oxide nanoparticles for biomedical applications

inferred← citeshttps://doi.org/10.1039/9781788019293-00305openalex-snapshot

Inorganic Nanomaterials in Vaccines

inferred← citeshttps://doi.org/10.1039/c8an01712copenalex-snapshot

An electrochemical enzymatic nanoreactor based on dendritic mesoporous silica nanoparticles for living cell H 2 O 2 detection

inferred← citeshttps://doi.org/10.1039/c8ra07849aopenalex-snapshot

Dual-generation dendritic mesoporous silica nanoparticles for co-delivery and kinetically sequential drug release

inferred← citeshttps://doi.org/10.1039/c9nr05922aopenalex-snapshot

A core–shell structure QRu-PLGA-RES-DS NP nanocomposite with photothermal response-induced M2 macrophage polarization for rheumatoid arthritis therapy

inferred← citeshttps://doi.org/10.1039/c9nr10813kopenalex-snapshot

Engineering of monodisperse core–shell up-conversion dendritic mesoporous silica nanocomposites with a tunable pore size

inferred← citeshttps://doi.org/10.1039/c9tb01846hopenalex-snapshot

Nanoporous hybrid core–shell nanoparticles for sequential release

inferred← citeshttps://doi.org/10.1039/d0cc03614eopenalex-snapshot

Synthesis of iron oxide nanocube patched Janus magnetic nanocarriers for cancer therapeutic applications

inferred← citeshttps://doi.org/10.1039/d0nr02044copenalex-snapshot

Multifunctional hierarchical mesoporous silica and black phosphorus nanohybrids as chemo-photothermal synergistic agents for enhanced cancer therapy

inferred← citeshttps://doi.org/10.1039/d0tb00342eopenalex-snapshot

Magnetic lanthanum-doped hydroxyapatite/chitosan scaffolds with endogenous stem cell-recruiting and immunomodulatory properties for bone regeneration

inferred← citeshttps://doi.org/10.1039/d0tb01868fopenalex-snapshot

Biomedical application of mesoporous silica nanoparticles as delivery systems: a biological safety perspective

inferred← citeshttps://doi.org/10.1039/d1bm00508aopenalex-snapshot

Inorganic material based macrophage regulation for cancer therapy: basic concepts and recent advances

inferred← citeshttps://doi.org/10.1039/d1bm01352aopenalex-snapshot

Facile synthesis of dendrimer like mesoporous silica nanoparticles to enhance targeted delivery of interleukin-22

inferred← citeshttps://doi.org/10.1039/d1cs01022kopenalex-snapshot

Silicon-containing nanomedicine and biomaterials: materials chemistry, multi-dimensional design, and biomedical application

inferred← citeshttps://doi.org/10.1039/d2sc00860bopenalex-snapshot

Macrophage-targeting oligopeptides from Mortierella alpina

inferred← citeshttps://doi.org/10.1039/d4nr00123kopenalex-snapshot

In situ carbonization metamorphoses porous silica particles into biodegradable therapeutic carriers of lesser consequence on TGF-β1 mediated fibrosis

inferred← citeshttps://doi.org/10.1073/pnas.1806908115openalex-snapshot

Functional muscle recovery with nanoparticle-directed M2 macrophage polarization in mice

inferred← citeshttps://doi.org/10.1080/17425247.2018.1517748openalex-snapshot

Rod-shaped mesoporous silica nanoparticles for nanomedicine: recent progress and perspectives

inferred← citeshttps://doi.org/10.1080/17425247.2023.2208344openalex-snapshot

Advances in engineering and delivery strategies for cytokine immunotherapy

inferred← citeshttps://doi.org/10.1080/17425247.2023.2273830openalex-snapshot

Silica nanoparticles for brain cancer

inferred← citeshttps://doi.org/10.1080/17435889.2025.2608357openalex-snapshot

The role of immunomodulatory nano systems in the treatment of sepsis: past, present, and future

inferred← citeshttps://doi.org/10.1088/1361-6528/aaff9eopenalex-snapshot

Targeted arsenite-loaded magnetic multifunctional nanoparticles for treatment of hepatocellular carcinoma

inferred← citeshttps://doi.org/10.1088/1748-605x/ac6b70openalex-snapshot

Gel dressing based on type I collagen modified with oligourethane and silica for skin wound healing

inferred← citeshttps://doi.org/10.1111/imm.13300openalex-snapshot

Macrophage reprogramming for therapy

inferred← citeshttps://doi.org/10.1111/odi.13023openalex-snapshot

Multifunctional nanocarriers for the treatment of periodontitis: Immunomodulatory, antimicrobial, and regenerative strategies

inferred← citeshttps://doi.org/10.1136/jitc-2021-002508openalex-snapshot

Mesoporous silica nanoparticles inflame tumors to overcome anti-PD-1 resistance through TLR4-NFκB axis

inferred← citeshttps://doi.org/10.11606/t.76.2020.tde-29092020-101056openalex-snapshot

Bionanomateriais para o cruzamento de barreira biológica e entrega controlada

inferred← citeshttps://doi.org/10.1177/08853282251319875openalex-snapshot

Stimulation of macrophage cell lines confined with silica and/or silicon particles and embedded in structured collagen gels

inferred← citeshttps://doi.org/10.1186/s11671-023-03926-1openalex-snapshot

One-pot, degradable, silica nanocarriers with encapsulated oligonucleotides for mitochondrial specific targeting

inferred← citeshttps://doi.org/10.1186/s12903-025-06999-9openalex-snapshot

Characterization and biocompatibility evaluation of a Ti@HA-GO@IL-4 bioactive composite coating for guided bone regeneration in dental implant applications

inferred← citeshttps://doi.org/10.1186/s12951-022-01343-7openalex-snapshot

The interaction between nanoparticles and immune system: application in the treatment of inflammatory diseases

inferred← citeshttps://doi.org/10.1186/s12951-023-01876-5openalex-snapshot

Remodeling the hepatic fibrotic microenvironment with emerging nanotherapeutics: a comprehensive review

inferred← citeshttps://doi.org/10.1186/s40824-021-00228-4openalex-snapshot

The effects of the molecular weights of hyaluronic acid on the immune responses

inferred← citeshttps://doi.org/10.1515/oms-2018-0001openalex-snapshot

Porous Materials for Immune Modulation

inferred← citeshttps://doi.org/10.15212/bioi-2020-0010openalex-snapshot

Bioactive Factors-imprinted Scaffold Vehicles for Promoting Bone Healing: The Potential Strategies and the Confronted Challenges for Clinical Production

inferred← citeshttps://doi.org/10.1631/jzus.b2400472openalex-snapshot

Role of the immune microenvironment in bone regeneration and progress in immune-modulating bone nanobiomaterials

inferred← citeshttps://doi.org/10.20998/2079-0821.2024.02.01openalex-snapshot

CONTEMPORARY TRENDS IN CERAMIC PRODUCTION: CREATION OF ALUMINOSILICATE PRODUCTS USING 3D PRINTING AND THE IMPACT OF INNOVATIVE APPROACHES ON THE INDUSTRY

inferred← citeshttps://doi.org/10.2174/1567201818666211214112710openalex-snapshot

Recent Advances in the Local Drug Delivery Systems for Improvement of Anticancer Therapy

inferred← citeshttps://doi.org/10.2174/1567201820666221108121347openalex-snapshot

Physical Characterization and Safety Evaluation of Folic Acid-conjugated Mesoporous Silica Nanoparticles Loaded with Rhodojaponin III

inferred← citeshttps://doi.org/10.2217/nnm-2018-0076openalex-snapshot

The Toxicity of Silica Nanoparticles to the Immune System

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