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Mesoporous Hydroxyapatite Nanoparticles Mediate the Release and Bioactivity of BMP-2 for Enhanced Bone Regeneration

https://doi.org/10.1021/acsbiomaterials.9b01954
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Outgoing claims: the papers this work cites, builds on, or argues with.

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Characterization of rhBMP-2 pharmacokinetics implanted with biomaterial carriers in the rat ectopic model
inferredcites →https://doi.org/10.1002/adma.201004637openalex-snapshot
Presentation of BMP‐2 from a Soft Biopolymeric Film Unveils its Activity on Cell Adhesion and Migration
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Structurally and Functionally Optimized Silk‐Fibroin–Gelatin Scaffold Using 3D Printing to Repair Cartilage Injury In Vitro and In Vivo
inferredcites →https://doi.org/10.1002/jbm.a.34241openalex-snapshot
BMP‐2 tethered hydroxyapatite for bone tissue regeneration: Coating chemistry and osteoblast attachment
inferredcites →https://doi.org/10.1002/jbm.a.35334openalex-snapshot
Biodegradable polymer scaffolds loaded with low‐dose BMP‐2 stimulate periodontal ligament cell differentiation
inferredcites →https://doi.org/10.1002/jor.20182openalex-snapshot
Global gene profiling reveals a downregulation of BMP gene expression in experimental atrophic nonunions compared to standard healing fractures
inferredcites →https://doi.org/10.1007/s11095-017-2147-xopenalex-snapshot
Formulation, Delivery and Stability of Bone Morphogenetic Proteins for Effective Bone Regeneration
inferredcites →https://doi.org/10.1016/j.actbio.2015.09.005openalex-snapshot
Silk fibroin as biomaterial for bone tissue engineering
inferredcites →https://doi.org/10.1016/j.actbio.2015.09.007openalex-snapshot
Nanostructured hydroxyapatite surfaces-mediated adsorption alters recognition of BMP receptor IA and bioactivity of bone morphogenetic protein-2
inferredcites →https://doi.org/10.1016/j.actbio.2016.12.012openalex-snapshot
Delivery vehicle effects on bone regeneration and heterotopic ossification induced by high dose BMP-2
inferredcites →https://doi.org/10.1016/j.actbio.2018.02.033openalex-snapshot
Hydroxyapatite nanobelt/polylactic acid Janus membrane with osteoinduction/barrier dual functions for precise bone defect repair
inferredcites →https://doi.org/10.1016/j.actbio.2019.04.023openalex-snapshot
Thermally triggered injectable chitosan/silk fibroin/bioactive glass nanoparticle hydrogels for in-situ bone formation in rat calvarial bone defects
inferredcites →https://doi.org/10.1016/j.addr.2003.08.010openalex-snapshot
Collagen sponges for bone regeneration with rhBMP-2
inferredcites →https://doi.org/10.1016/j.bbrc.2013.09.036openalex-snapshot
Surface-induced conformational and functional changes of bone morphogenetic protein-2 adsorbed onto single-walled carbon nanotubes
inferredcites →https://doi.org/10.1016/j.biomaterials.2003.10.081openalex-snapshot
Hydroxyapatite particles as a controlled release carrier of protein
inferredcites →https://doi.org/10.1016/j.biomaterials.2008.04.031openalex-snapshot
Retention of in vitro and in vivo BMP-2 bioactivities in sustained delivery vehicles for bone tissue engineering
inferredcites →https://doi.org/10.1016/j.biomaterials.2015.01.017openalex-snapshot
Composite scaffolds of nano-hydroxyapatite and silk fibroin enhance mesenchymal stem cell-based bone regeneration via the interleukin 1 alpha autocrine/paracrine signaling loop
inferredcites →https://doi.org/10.1016/j.bone.2008.05.021openalex-snapshot
Growth of new bone guided by implants in a murine calvarial model
inferredcites →https://doi.org/10.1016/j.carbpol.2014.04.094openalex-snapshot
Composite chitosan/silk fibroin nanofibers for modulation of osteogenic differentiation and proliferation of human mesenchymal stem cells
inferredcites →https://doi.org/10.1016/j.chroma.2014.10.080openalex-snapshot
Structures of multidomain proteins adsorbed on hydrophobic interaction chromatography surfaces
inferredcites →https://doi.org/10.1016/j.colsurfb.2016.04.045openalex-snapshot
Magnesium modification up-regulates the bioactivity of bone morphogenetic protein-2 upon calcium phosphate cement via enhanced BMP receptor recognition and Smad signaling pathway
inferredcites →https://doi.org/10.1016/j.ijbiomac.2016.12.046openalex-snapshot
Chitosan based nanofibers in bone tissue engineering
inferredcites →https://doi.org/10.1016/j.ijpharm.2017.10.008openalex-snapshot
ZnO-based nanocarriers for drug delivery application: From passive to smart strategies
inferredcites →https://doi.org/10.1016/j.jcis.2010.08.013openalex-snapshot
Influence of crystallite size of nanophased hydroxyapatite on fibronectin and osteonectin adsorption and on MC3T3-E1 osteoblast adhesion and morphology
inferredcites →https://doi.org/10.1016/j.jinorgbio.2005.01.011openalex-snapshot
Adsorption of recombinant human bone morphogenetic protein rhBMP-2m onto hydroxyapatite
inferredcites →https://doi.org/10.1016/j.jmgm.2017.08.005openalex-snapshot
BMP-2 and BMP-9 binding specificities with ALK-3 in aqueous solution with dynamics
inferredcites →https://doi.org/10.1016/j.jphotobiol.2016.12.005openalex-snapshot
Agarose encapsulated mesoporous carbonated hydroxyapatite nanocomposites powder for drug delivery
inferredcites →https://doi.org/10.1016/j.jphotobiol.2019.111563openalex-snapshot
Impact of bone extracellular matrix mineral based nanoparticles on structure and stability of purified bone morphogenetic protein 2 (BMP-2)
inferredcites →https://doi.org/10.1016/j.msec.2013.04.026openalex-snapshot
Preparation, characterization and biological test of 3D-scaffolds based on chitosan, fibroin and hydroxyapatite for bone tissue engineering
inferredcites →https://doi.org/10.1016/j.msec.2014.01.004openalex-snapshot
Surface functionalization of nanoporous alumina with bone morphogenetic protein 2 for inducing osteogenic differentiation of mesenchymal stem cells
inferredcites →https://doi.org/10.1016/j.msec.2014.07.030openalex-snapshot
Production of hydroxyapatite layers on the plasma electrolytically oxidized surface of titanium alloys
inferredcites →https://doi.org/10.1016/j.msec.2015.04.033openalex-snapshot
Preparation and characterization of nano-sized hydroxyapatite/alginate/chitosan composite scaffolds for bone tissue engineering
inferredcites →https://doi.org/10.1016/j.msec.2016.11.054openalex-snapshot
Microstructural control of modular peptide release from microporous biphasic calcium phosphate
inferredcites →https://doi.org/10.1016/j.msec.2017.03.186openalex-snapshot
BMP-2 immobilized PLGA/hydroxyapatite fibrous scaffold via polydopamine stimulates osteoblast growth
inferredcites →https://doi.org/10.1016/j.nano.2014.09.014openalex-snapshot
Mesoporous silica nanoparticles in drug delivery and biomedical applications
inferredcites →https://doi.org/10.1016/j.vaccine.2015.11.059openalex-snapshot
Optimization of physiological properties of hydroxyapatite as a vaccine adjuvant
inferredcites →https://doi.org/10.1021/acsami.5b04009openalex-snapshot
Ultrafast Spreading Effect Induced Rapid Cell Trapping into Porous Scaffold with Superhydrophilic Surface
inferredcites →https://doi.org/10.1021/acsami.5b04962openalex-snapshot
Modulation of Bone-Specific Tissue Regeneration by Incorporating Bone Morphogenetic Protein and Controlling the Shell Thickness of Silk Fibroin/Chitosan/Nanohydroxyapatite Core–Shell Nanofibrous Membranes
inferredcites →https://doi.org/10.1021/acsbiomaterials.6b00632openalex-snapshot
Multiscale Porosity Directs Bone Regeneration in Biphasic Calcium Phosphate Scaffolds
inferredcites →https://doi.org/10.1021/acsbiomaterials.9b01022openalex-snapshot
Multifunctional Triple-Layered Composite Scaffolds Combining Platelet-Rich Fibrin Promote Bone Regeneration
inferredcites →https://doi.org/10.1021/bm401309uopenalex-snapshot
In Situ Controlled Release of rhBMP-2 in Gelatin-Coated 3D Porous Poly(ε-caprolactone) Scaffolds for Homogeneous Bone Tissue Formation
inferredcites →https://doi.org/10.1021/bm5006855openalex-snapshot
Sulfated Glycosaminoglycans Exploit the Conformational Plasticity of Bone Morphogenetic Protein-2 (BMP-2) and Alter the Interaction Profile with Its Receptor
inferredcites →https://doi.org/10.1021/ja042898oopenalex-snapshot
Interpretation of Protein Adsorption: Surface-Induced Conformational Changes
inferredcites →https://doi.org/10.1038/ncb0402-e65openalex-snapshot
Networks and crosstalk: integrin signalling spreads
inferredcites →https://doi.org/10.1038/srep12694openalex-snapshot
Calcium ion-induced formation of β-sheet/-turn structure leading to alteration of osteogenic activity of bone morphogenetic protein-2
inferredcites →https://doi.org/10.1039/c7bm00869dopenalex-snapshot
The osteoimmunomodulatory property of a barrier collagen membrane and its manipulation via coating nanometer-sized bioactive glass to improve guided bone regeneration
inferredcites →https://doi.org/10.1074/jbc.m706029200openalex-snapshot
Structure Analysis of Bone Morphogenetic Protein-2 Type I Receptor Complexes Reveals a Mechanism of Receptor Inactivation in Juvenile Polyposis Syndrome
inferredcites →https://doi.org/10.1088/0957-4484/22/10/105708openalex-snapshot
The role of surface charge on the uptake and biocompatibility of hydroxyapatite nanoparticles with osteoblast cells
inferredcites →https://doi.org/10.1088/1748-6041/9/6/065006openalex-snapshot
Efficacy of rhBMP-2 loaded PCL/PLGA/ β -TCP guided bone regeneration membrane fabricated by 3D printing technology for reconstruction of calvaria defects in rabbit
inferredcites →https://doi.org/10.1089/ten.tea.2013.0358openalex-snapshot
Controlled Multiple Growth Factor Delivery from Bone Tissue Engineering Scaffolds via Designed Affinity
inferredcites →https://doi.org/10.1089/ten.teb.2015.0357openalex-snapshot
A Review of the Clinical Side Effects of Bone Morphogenetic Protein-2
inferredcites →https://doi.org/10.1111/jphp.12506openalex-snapshot
Bone morphogenetic protein-2 and bone therapy: successes and pitfalls
inferredcites →https://doi.org/10.1146/annurev-cellbio-111315-125341openalex-snapshot
Focal Adhesion–Independent Cell Migration
inferredcites →https://doi.org/10.1155/2015/137823openalex-snapshot
Transforming Growth Factor Beta Family: Insight into the Role of Growth Factors in Regulation of Fracture Healing Biology and Potential Clinical Applications
inferredcites →https://doi.org/10.1155/2015/281909openalex-snapshot
BMP-2 Grafted nHA/PLGA Hybrid Nanofiber Scaffold Stimulates Osteoblastic Cells Growth
inferredcites →https://doi.org/10.1166/jbn.2014.1893openalex-snapshot
Nano-Hydroxyapatite Composite Biomaterials for Bone Tissue Engineering—A Review
inferredcites →https://doi.org/10.1166/jnn.2018.15365openalex-snapshot
Magnetic Lamellar Nano-Hydroxyapatite as a Vector for Gene Transfection in Three-Dimensional Cell Culture
inferredcites →https://doi.org/10.1186/1472-6807-7-6openalex-snapshot
A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor
inferredcites →https://doi.org/10.1186/1749-799x-6-8openalex-snapshot
The role of FGF-2 and BMP-2 in regulation of gene induction, cell proliferation and mineralization.
inferredcites →https://doi.org/10.1210/en.130.3.1318openalex-snapshot
Recombinant human bone morphogenetic protein-2 induces osteoblastic differentiation in W-20-17 stromal cells
inferredcites →https://doi.org/10.1359/jbmr.2002.17.3.513openalex-snapshot
Differential Temporal Expression of Members of the Transforming Growth Factor β Superfamily During Murine Fracture Healing
inferredcites →https://doi.org/10.1529/biophysj.106.103168openalex-snapshot
Understanding Adsorption-Desorption Dynamics of BMP-2 on Hydroxyapatite (001) Surface
inferredcites →https://doi.org/10.2147/ijn.s73780openalex-snapshot
Response of human mesenchymal stem cells to intrafibrillar nanohydroxyapatite content and extrafibrillar nanohydroxyapatite in biomimetic chitosan/silk fibroin/nanohydroxyapatite nanofibrous membrane scaffolds
inferredcites →https://doi.org/10.2147/ijn.s74677openalex-snapshot
BMP2-loaded hollow hydroxyapatite microspheres exhibit enhanced osteoinduction and osteogenicity in large bone defects
inferredcites →https://doi.org/10.2174/0929866525666171221115033openalex-snapshot
Utilization of Proteins and Peptides to Create Organic-Hydroxyapatite Hybrids
inferredcites →https://doi.org/10.3109/21691401.2014.955107openalex-snapshot
Application of gold nanoparticles in biomedical and drug delivery
inferredcites →https://doi.org/10.3892/mmr.2015.3249openalex-snapshot
Radix Dipsaci total saponins stimulate MC3T3-E1 cell differentiation via the bone morphogenetic protein-2/MAPK/Smad-dependent Runx2 pathway

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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