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Rerouting the Organocatalytic Benzoin Reaction toward Aldehyde Deuteration

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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/adsc.200900247openalex-snapshot
A Direct Intermolecular Cross‐Benzoin Type Reaction: N‐Heterocyclic Carbene‐Catalyzed Coupling of Aromatic Aldehydes with Trifluoromethyl Ketones
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Rate and Equilibrium Constants for the Addition of N‐Heterocyclic Carbenes into Benzaldehydes: A Remarkable 2‐Substituent Effect
inferredcites →https://doi.org/10.1002/ange.201702997openalex-snapshot
Iridium‐Catalyzed Formyl‐Selective Deuteration of Aldehydes
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In the Golden Age of Organocatalysis
inferredcites →https://doi.org/10.1002/anie.200700039openalex-snapshot
The Renaissance of H/D Exchange
inferredcites →https://doi.org/10.1002/anie.200702210openalex-snapshot
Organocatalysis Lost: Modern Chemistry, Ancient Chemistry, and an Unseen Biosynthetic Apparatus
inferredcites →https://doi.org/10.1002/anie.201205878openalex-snapshot
Umpolung by N‐Heterocyclic Carbenes: Generation and Reactivity of the Elusive 2,2‐Diamino Enols (Breslow Intermediates)
inferredcites →https://doi.org/10.1002/anie.201409004openalex-snapshot
Deconstructing Covalent Organocatalysis
inferredcites →https://doi.org/10.1002/anie.201704146openalex-snapshot
Deuterium‐ and Tritium‐Labelled Compounds: Applications in the Life Sciences
inferredcites →https://doi.org/10.1002/anie.201806148openalex-snapshot
Palladium/Rhodium Cooperative Catalysis for the Production of Aryl Aldehydes and Their Deuterated Analogues Using the Water–Gas Shift Reaction
inferredcites →https://doi.org/10.1002/anie.201811522openalex-snapshot
Deoxygenative Deuteration of Carboxylic Acids with D 2 O
inferredcites →https://doi.org/10.1002/cjoc.202000107openalex-snapshot
N‐Heterocyclic Carbene Organocatalysis: Activation Modes and Typical Reactive Intermediates
inferredcites →https://doi.org/10.1002/ejoc.202100384openalex-snapshot
Kinetic and Structure‐Activity Studies of the Triazolium Ion‐ Catalyzed Intramolecular Stetter Reaction
inferredcites →https://doi.org/10.1016/0009-2614(95)00905-jopenalex-snapshot
The Grotthuss mechanism
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Development and Application of New Steric Substituent Parameters in Drug Design
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Insights into enzyme structure and dynamics elucidated by amide H/D exchange mass spectrometry
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Mesoionic Carbene (MIC)-Catalyzed H/D Exchange at Formyl Groups
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Enantioselective organocatalysis
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Microstructure and concentration fluctuations in alcohol–Toluene and alcohol-Cyclohexane binary liquids: A small angle neutron scattering study
inferredcites →https://doi.org/10.1021/acs.chemrev.5b00060openalex-snapshot
Organocatalytic Reactions Enabled by N-Heterocyclic Carbenes
inferredcites →https://doi.org/10.1021/acs.orglett.8b00016openalex-snapshot
One-Pot Synthesis of Deuterated Aldehydes from Arylmethyl Halides
inferredcites →https://doi.org/10.1021/ar400239vopenalex-snapshot
On the Mechanism of N-Heterocyclic Carbene-Catalyzed Reactions Involving Acyl Azoliums
inferredcites →https://doi.org/10.1021/cr068372zopenalex-snapshot
Organocatalysis by N-Heterocyclic Carbenes
inferredcites →https://doi.org/10.1021/cr068444mopenalex-snapshot
Thiamin Diphosphate Catalysis: Enzymic and Nonenzymic Covalent Intermediates
inferredcites →https://doi.org/10.1021/cr078412eopenalex-snapshot
Introduction: Organocatalysis
inferredcites →https://doi.org/10.1021/cr60279a004openalex-snapshot
Kinetic isotope effects as a valid measure of structure-reactivity relations. Isotope effects and nonclassical theory
inferredcites →https://doi.org/10.1021/ja01547a064openalex-snapshot
On the Mechanism of Thiamine Action. IV.1 Evidence from Studies on Model Systems
inferredcites →https://doi.org/10.1021/ja01564a064openalex-snapshot
RAPID DEUTERIUM EXCHANGE IN THIAZOLIUM SALTS 1
inferredcites →https://doi.org/10.1021/ja308420copenalex-snapshot
Proton Transfer Reactions of Triazol-3-ylidenes: Kinetic Acidities and Carbon Acid p K a Values for Twenty Triazolium Salts in Aqueous Solution
inferredcites →https://doi.org/10.1021/jm4007998openalex-snapshot
Using Deuterium in Drug Discovery: Leaving the Label in the Drug
inferredcites →https://doi.org/10.1038/nature07367openalex-snapshot
The advent and development of organocatalysis
inferredcites →https://doi.org/10.1038/nm0613-656openalex-snapshot
Heavy drugs draw heavy interest from pharma backers
inferredcites →https://doi.org/10.1038/s41557-019-0258-1openalex-snapshot
Unravelling mechanistic features of organocatalysis with in situ modifications at the secondary sphere
inferredcites →https://doi.org/10.1038/s41586-019-1384-zopenalex-snapshot
Holistic prediction of enantioselectivity in asymmetric catalysis
inferredcites →https://doi.org/10.1038/s41929-019-0370-zopenalex-snapshot
Practical synthesis of C1 deuterated aldehydes enabled by NHC catalysis
inferredcites →https://doi.org/10.1039/c0cc02013copenalex-snapshot
N-heterocyclic carbene catalysed asymmetric cross-benzoin reactions of heteroaromatic aldehydes with trifluoromethyl ketones
inferredcites →https://doi.org/10.1039/c0cc03367gopenalex-snapshot
pK a s of the conjugate acids of N-heterocyclic carbenes in water
inferredcites →https://doi.org/10.1039/c1sc00397fopenalex-snapshot
The effect of the N-mesityl group in NHC-catalyzed reactions
inferredcites →https://doi.org/10.1039/c2sc22137copenalex-snapshot
Mechanistic insights into the triazolylidene-catalysed Stetter and benzoin reactions: role of the N-aryl substituent
inferredcites →https://doi.org/10.1039/c9sc05132eopenalex-snapshot
Formyl-selective deuteration of aldehydes with D 2 O via synergistic organic and photoredox catalysis
inferredcites →https://doi.org/10.1039/d0ob02207aopenalex-snapshot
Kinetic and structure–activity studies of the triazolium ion-catalysed benzoin condensation
inferredcites →https://doi.org/10.1055/s-0036-1588540openalex-snapshot
Catalytic Deuteration of Aldehydes with D2O
inferredcites →https://doi.org/10.1055/s-0040-1707993openalex-snapshot
N-Heterocyclic Carbene Catalyzed Deuteration of Aldehydes in D2O
inferredcites →https://doi.org/10.1073/pnas.1016087107openalex-snapshot
Organocatalysis
inferredcites →https://doi.org/10.1103/physreve.99.062607openalex-snapshot
Microstructure of nonideal methanol binary liquid mixtures
inferredcites →https://doi.org/10.1126/science.1259203openalex-snapshot
Nanomole-scale high-throughput chemistry for the synthesis of complex molecules
inferredcites →https://doi.org/10.1177/1060028018797110openalex-snapshot
Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Small Data Can Play a Big Role in Chemical Discovery
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