On the public citation graph

Biochemical and Structural Insights into the Aminotransferase CrmG in Caerulomycin Biosynthesis

https://doi.org/10.1021/acschembio.5b00984

0 signed · 91 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

Is this your work? Sign in with ORCID and put your name on the claims that are yours.

Claim with ORCID

Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.

See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/anie.200801204openalex-snapshot

Natural‐Product Sugar Biosynthesis and Enzymatic Glycodiversification

inferredcites →https://doi.org/10.1002/cbic.200600371openalex-snapshot

Elaboration of Neosamine Rings in the Biosynthesis of Neomycin and Butirosin

inferredcites →https://doi.org/10.1002/cbic.201300153openalex-snapshot

A Single PLP‐Dependent Enzyme PctV Catalyzes the Transformation of 3‐Dehydroshikimate into 3‐Aminobenzoate in the Biosynthesis of Pactamycin

inferredcites →https://doi.org/10.1002/cbic.201500426openalex-snapshot

Mechanism‐Based Trapping of the Quinonoid Intermediate by Using the K276R Mutant of PLP‐Dependent 3‐Aminobenzoate Synthase PctV in the Biosynthesis of Pactamycin

inferredcites →https://doi.org/10.1002/chem.200900939openalex-snapshot

A New and Flexible Synthesis of 4‐Hydroxypyridines: Rapid Access to Caerulomycins A, E and Functionalized Terpyridines

inferredcites →https://doi.org/10.1002/prot.21076openalex-snapshot

Crystal structures of the PLP‐ and PMP‐bound forms of BtrR, a dual functional aminotransferase involved in butirosin biosynthesis

inferredcites →https://doi.org/10.1002/prot.24844openalex-snapshot

Structural characterization of AtmS13, a putative sugar aminotransferase involved in indolocarbazole AT2433 aminopentose biosynthesis

inferredcites →https://doi.org/10.1002/tcr.20042openalex-snapshot

Dual substrate recognition of aminotransferases

inferredcites →https://doi.org/10.1007/s00253-012-4103-3openalex-snapshot

Features and technical applications of ω-transaminases

inferredcites →https://doi.org/10.1007/s10295-009-0579-yopenalex-snapshot

Production of rosamicin derivatives in Micromonospora rosaria by introduction of d-mycinose biosynthetic gene with ΦC31-derived integration vector pSET152

inferredcites →https://doi.org/10.1007/s10969-012-9129-3openalex-snapshot

phenix.mr_rosetta: molecular replacement and model rebuilding with Phenix and Rosetta

inferredcites →https://doi.org/10.1016/0378-1119(92)90603-mopenalex-snapshot

Analysis of Streptomyces avermitilis genes required for avermectin biosynthesis utilizing a novel integration vector

inferredcites →https://doi.org/10.1016/j.bbapap.2011.02.003openalex-snapshot

Mechanisms and structures of vitamin B6-dependent enzymes involved in deoxy sugar biosynthesis

inferredcites →https://doi.org/10.1016/j.bbapap.2015.02.023openalex-snapshot

A subfamily of PLP-dependent enzymes specialized in handling terminal amines

inferredcites →https://doi.org/10.1016/j.bbrc.2014.03.125openalex-snapshot

Crystal structure of the catalytic domain of PigE: A transaminase involved in the biosynthesis of 2-methyl-3-n-amyl-pyrrole (MAP) from Serratia sp. FS14

inferredcites →https://doi.org/10.1016/j.bmcl.2013.08.017openalex-snapshot

Generation by mutasynthesis of potential neuroprotectant derivatives of the bipyridyl collismycin A

inferredcites →https://doi.org/10.1016/j.chembiol.2004.04.015openalex-snapshot

Characterization and Investigation of Substrate Specificity of the Sugar Aminotransferase WecE from E. coli K12

inferredcites →https://doi.org/10.1016/j.chembiol.2012.01.014openalex-snapshot

Elucidating the Biosynthetic Pathway for the Polyketide-Nonribosomal Peptide Collismycin A: Mechanism for Formation of the 2,2′-bipyridyl Ring

inferredcites →https://doi.org/10.1016/j.chembiol.2013.06.014openalex-snapshot

Engineering the Biosynthesis of the Polyketide-Nonribosomal Peptide Collismycin A for Generation of Analogs with Neuroprotective Activity

inferredcites →https://doi.org/10.1016/j.chembiol.2014.12.012openalex-snapshot

Delineating the Biosynthesis of Gentamicin X2, the Common Precursor of the Gentamicin C Antibiotic Complex

inferredcites →https://doi.org/10.1016/j.molcatb.2005.09.004openalex-snapshot

Revisit of aminotransferase in the genomic era and its application to biocatalysis

inferredcites →https://doi.org/10.1016/s0040-4039(01)86882-9openalex-snapshot

The structures of orellanine and orelline

inferredcites →https://doi.org/10.1016/s0076-6879(09)04620-5openalex-snapshot

Chapter 20 Biosynthetic Enzymes for the Aminoglycosides Butirosin and Neomycin

inferredcites →https://doi.org/10.1021/acschembio.5b00244openalex-snapshot

Structural Basis for the Stereochemical Control of Amine Installation in Nucleotide Sugar Aminotransferases

inferredcites →https://doi.org/10.1021/bi700751dopenalex-snapshot

Molecular Architecture of DesI: A Key Enzyme in the Biosynthesis of Desosamine,

inferredcites →https://doi.org/10.1021/bi9021186openalex-snapshot

Investigation of Anticapsin Biosynthesis Reveals a Four-Enzyme Pathway to Tetrahydrotyrosine in Bacillus subtilis

inferredcites →https://doi.org/10.1021/cr0404085openalex-snapshot

2-Deoxystreptamine: Central Scaffold of Aminoglycoside Antibiotics

inferredcites →https://doi.org/10.1021/ja010587xopenalex-snapshot

Study of C-4 Deoxygenation in the Biosynthesis of Desosamine: Evidence Implicating a Novel Mechanism

inferredcites →https://doi.org/10.1021/ja3016457openalex-snapshot

Caerulomycins and Collismycins Share a Common Paradigm for 2,2′-Bipyridine Biosynthesis via an Unusual Hybrid Polyketide–Peptide Assembly Logic

inferredcites →https://doi.org/10.1021/ja3069243openalex-snapshot

Characterization of Streptonigrin Biosynthesis Reveals a Cryptic Carboxyl Methylation and an Unusual Oxidative Cleavage of a N–C Bond

inferredcites →https://doi.org/10.1021/ja410513gopenalex-snapshot

Insights into Caerulomycin A Biosynthesis: A Two-Component Monooxygenase CrmH-Catalyzed Oxime Formation

inferredcites →https://doi.org/10.1021/ja800951eopenalex-snapshot

Identifying the Minimal Enzymes Required for Anhydrotetracycline Biosynthesis

inferredcites →https://doi.org/10.1021/jo972022iopenalex-snapshot

First Syntheses of Caerulomycin E and Collismycins A and C. A New Synthesis of Caerulomycin A

inferredcites →https://doi.org/10.1021/np200258hopenalex-snapshot

Cytotoxic Bipyridines from the Marine-Derived Actinomycete Actinoalloteichus cyanogriseus WH1-2216-6

inferredcites →https://doi.org/10.1021/ol026135mopenalex-snapshot

Total Synthesis of Caerulomycin C via the Halogen Dance Reaction

inferredcites →https://doi.org/10.1021/ol202245sopenalex-snapshot

Cyclic Bipyridine Glycosides from the Marine-Derived Actinomycete Actinoalloteichus cyanogriseus WH1-2216-6

inferredcites →https://doi.org/10.1021/ol300589ropenalex-snapshot

Identification of Caerulomycin A Gene Cluster Implicates a Tailoring Amidohydrolase

inferredcites →https://doi.org/10.1021/ol5019757openalex-snapshot

Acyclic Congeners from Actinoalloteichus cyanogriseus Provide Insights into Cyclic Bipyridine Glycoside Formation

inferredcites →https://doi.org/10.1038/ja.2007.52openalex-snapshot

GriC and GriD Constitute a Carboxylic Acid Reductase Involved in Grixazone Biosynthesis in Streptomyces griseus

inferredcites →https://doi.org/10.1039/b209799kopenalex-snapshot

Biosynthesis of aminoglycoside antibiotics: cloning, expression and characterisation of an aminotransferase involved in the pathway to 2-deoxystreptamineElectronic supplementary information (ESI) available: LC-MS, TLC and ESI-Q-TOF MS. See http://www.rsc.org/suppdata/cc/b2/b209799k/

inferredcites →https://doi.org/10.1039/b604709mopenalex-snapshot

Biosynthesis of 2-deoxystreptamine-containing aminoglycoside antibiotics

inferredcites →https://doi.org/10.1039/b911956fopenalex-snapshot

Post-PKS tailoring steps in natural product-producing actinomycetes from the perspective of combinatorial biosynthesis

inferredcites →https://doi.org/10.1039/c2np20039bopenalex-snapshot

The structural biology of enzymes involved in natural product glycosylation

inferredcites →https://doi.org/10.1039/c2np20092aopenalex-snapshot

2-Deoxystreptamine-containing aminoglycoside antibiotics: Recent advances in the characterization and manipulation of their biosynthetic pathways

inferredcites →https://doi.org/10.1073/pnas.0337542100openalex-snapshot

PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin

inferredcites →https://doi.org/10.1073/pnas.120163297openalex-snapshot

One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products

inferredcites →https://doi.org/10.1074/jbc.m113.500637openalex-snapshot

The Structure of NtdA, a Sugar Aminotransferase Involved in the Kanosamine Biosynthetic Pathway in Bacillus subtilis, Reveals a New Subclass of Aminotransferases

inferredcites →https://doi.org/10.1074/jbc.m113.545871openalex-snapshot

Caerulomycin A Enhances Transforming Growth Factor-β (TGF-β)-Smad3 Protein Signaling by Suppressing Interferon-γ (IFN-γ)-Signal Transducer and Activator of Transcription 1 (STAT1) Protein Signaling to Expand Regulatory T Cells (Tregs)

inferredcites →https://doi.org/10.1074/jbc.m512987200openalex-snapshot

Structural and Functional Characterization of PseC, an Aminotransferase Involved in the Biosynthesis of Pseudaminic Acid, an Essential Flagellar Modification in Helicobacter pylori

inferredcites →https://doi.org/10.1093/nar/25.11.2227openalex-snapshot

A rapid and efficient method for site-directed mutagenesis using one- step overlap extension PCR

inferredcites →https://doi.org/10.1097/tp.0000000000000119openalex-snapshot

Cerulomycin A

inferredcites →https://doi.org/10.1107/s0021889897006766openalex-snapshot

MOLREP : an Automated Program for Molecular Replacement

inferredcites →https://doi.org/10.1107/s090744491003982xopenalex-snapshot

An introduction to data reduction: space-group determination, scaling and intensity statistics

inferredcites →https://doi.org/10.1107/s0907444910048675openalex-snapshot

iMOSFLM: a new graphical interface for diffraction-image processing withMOSFLM

inferredcites →https://doi.org/10.1107/s0907444911001314openalex-snapshot

REFMAC 5 for the refinement of macromolecular crystal structures

inferredcites →https://doi.org/10.1110/ps.062711007openalex-snapshot

Molecular architecture of DesV from Streptomyces venezuelae: A PLP‐dependent transaminase involved in the biosynthesis of the unusual sugar desosamine

inferredcites →https://doi.org/10.1111/bph.13051openalex-snapshot

Novel immunosuppressive agent c aerulomycin A exerts its effect by depleting cellular iron content

inferredcites →https://doi.org/10.1111/j.1365-2958.2005.04602.xopenalex-snapshot

Biosynthesis of the red antibiotic, prodigiosin, in Serratia: identification of a novel 2‐methyl‐3‐n‐amyl‐pyrrole (MAP) assembly pathway, definition of the terminal condensing enzyme, and implications for undecylprodigiosin biosynthesis in Streptomyces

inferredcites →https://doi.org/10.1128/jb.181.1.204-211.1999openalex-snapshot

Evidence that the Extracytoplasmic Function Sigma Factor ς E Is Required for Normal Cell Wall Structure in Streptomyces coelicolor A3(2)

inferredcites →https://doi.org/10.1128/jb.186.17.5596-5602.2004openalex-snapshot

Functional Characterization of an Aminotransferase Required for Pyoverdine Siderophore Biosynthesis in Pseudomonas aeruginosa PAO1

inferredcites →https://doi.org/10.1139/m59-039openalex-snapshot

CAERULOMYCIN, A NEW ANTIBIOTIC FROM STREPTOMYCES CAERULEUS BALDACCI: I. PRODUCTION, ISOLATION, ASSAY, AND BIOLOGICAL PROPERTIES

inferredcites →https://doi.org/10.1139/v88-031openalex-snapshot

The biosynthesis of caerulomycins in Streptomyces caeruleus. Isolation of a new caerulomycin and incorporation of picolinic acid and glycerol into caerulomycin A

inferredcites →https://doi.org/10.1146/annurev.biochem.73.011303.074021openalex-snapshot

Pyridoxal Phosphate Enzymes: Mechanistic, Structural, and Evolutionary Considerations

inferredcites →https://doi.org/10.1371/journal.pone.0058298openalex-snapshot

Determination of the Structure of the Catabolic N-Succinylornithine Transaminase (AstC) from Escherichia coli

inferredcites →https://doi.org/10.1371/journal.pone.0107051openalex-snapshot

Caerulomycin A Suppresses Immunity by Inhibiting T Cell Activity

inferredcites →https://doi.org/10.7164/antibiotics.47.1072openalex-snapshot

Collismycins A and B, novel non-steroidal inhibitors of denamethasone-glucocorticoid receptor binding.

inferredcites →https://doi.org/10.7164/antibiotics.52.505openalex-snapshot

Novel Antibiotics Pyrisulfoxin A and B Produced by Streptomyces californicus.

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4663831openalex-extracted

inferred← citeshttps://doi.org/10.1007/s10295-018-2092-7openalex-snapshot

Discovery of caerulomycin/collismycin-type 2,2′-bipyridine natural products in the genomic era

inferred← citeshttps://doi.org/10.1016/b978-0-12-409547-2.14711-0openalex-snapshot

Assembly Line and Post-PKS Modifications in the Biosynthesis of Marine Polyketide Natural Products

inferred← citeshttps://doi.org/10.1016/j.bbrc.2017.03.147openalex-snapshot

Pyridoxamine scavenges protein carbonyls and inhibits protein aggregation in oxidative stress-induced human HepG2 hepatocytes

inferred← citeshttps://doi.org/10.1016/j.bbrc.2023.07.009openalex-snapshot

Co-crystal structure provides insights on transaminase CrmG recognition amino donor L-Arg

inferred← citeshttps://doi.org/10.1016/j.cell.2017.06.009openalex-snapshot

RAS Proteins and Their Regulators in Human Disease

inferred← citeshttps://doi.org/10.1016/j.scp.2024.101504openalex-snapshot

Stemphylium lycopersici immobilized in mesoporous of type MCM 48 as biocatalyst for ω-transamination reactions

inferred← citeshttps://doi.org/10.1016/j.synbio.2017.07.002openalex-snapshot

Characterization of the metallo-dependent amidohydrolases responsible for “auxiliary” leucinyl removal in the biosynthesis of 2,2′-bipyridine antibiotics

inferred← citeshttps://doi.org/10.1021/acs.chemrev.6b00621openalex-snapshot

Heteroatom–Heteroatom Bond Formation in Natural Product Biosynthesis

inferred← citeshttps://doi.org/10.1021/acs.jnatprod.5c00682openalex-snapshot

Halogenated Dipyridine Alkaloids from Actinoalloteichus cyanogriseus and Its Mutant Strain upon Precursor Feeding

inferred← citeshttps://doi.org/10.1021/acs.joc.0c00339openalex-snapshot

Discovery of an Isothiazolinone-Containing Antitubercular Natural Product Levesquamide

inferred← citeshttps://doi.org/10.1021/acs.orglett.1c04239openalex-snapshot

Investigation of 2,2′-Bipyridine Biosynthesis Reveals a Common Two-Component System for Aldehydes Production by Carboxylate Reduction

inferred← citeshttps://doi.org/10.1021/acscatal.2c02954openalex-snapshot

Coupled Natural Fusion Enzymes in a Novel Biocatalytic Cascade Convert Fatty Acids to Amines

inferred← citeshttps://doi.org/10.1021/acsomega.6c04357openalex-snapshot

FBMN-Guided Discovery of Cyanogrisides from Mutant Strain CRM005 and Structural Diversification

inferred← citeshttps://doi.org/10.1038/s41467-021-23475-4openalex-snapshot

Caerulomycin and collismycin antibiotics share a trans-acting flavoprotein-dependent assembly line for 2,2’-bipyridine formation

inferred← citeshttps://doi.org/10.1038/s42003-020-01184-wopenalex-snapshot

Structural studies reveal flexible roof of active site responsible for ω-transaminase CrmG overcoming by-product inhibition

inferred← citeshttps://doi.org/10.1039/c6sc00771fopenalex-snapshot

Flavoenzyme CrmK-mediated substrate recycling in caerulomycin biosynthesis

inferred← citeshttps://doi.org/10.1039/c8ob02846jopenalex-snapshot

Identification of the common biosynthetic gene cluster for both antimicrobial streptoaminals and antifungal 5-alkyl-1,2,3,4-tetrahydroquinolines

inferred← citeshttps://doi.org/10.1039/c9qo00685kopenalex-snapshot

Caerulomycins from Actinoalloteichus cyanogriseus WH1-2216-6: isolation, identification and cytotoxicity

inferred← citeshttps://doi.org/10.1039/d3ra07081fopenalex-snapshot

Natural transaminase fusions for biocatalysis

inferred← citeshttps://doi.org/10.1093/nsr/nww045openalex-snapshot

Biosynthesis and molecular engineering of templated natural products

inferred← citeshttps://doi.org/10.1186/s12934-020-01418-wopenalex-snapshot

Activation and enhancement of caerulomycin A biosynthesis in marine-derived Actinoalloteichus sp. AHMU CJ021 by combinatorial genome mining strategies

inferred← citeshttps://doi.org/10.3390/md18050277openalex-snapshot

The Influence of Caerulomycin A on the Intestinal Microbiota in SD Rats

inferred← citeshttps://doi.org/10.6023/cjoc202204035openalex-snapshot

Fermentation Optimization of the Caerulomycin H and the Synthesis of Cyanogriside K

Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.