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Systemic Anti-Inflammatory Therapy Aided by Curcumin-Laden Double-Headed Nanoparticles Combined with Injectable Long-Acting Insulin in a Rodent Model of Diabetes Eye Disease

https://doi.org/10.1021/acsnano.3c00535
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Outgoing claims: the papers this work cites, builds on, or argues with.

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Association of Cataract Surgery With Risk of Diabetic Retinopathy Among Asian Participants in the Singapore Epidemiology of Eye Diseases Study
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Effect of insulin and its combination with resveratrol or curcumin in attenuation of diabetic neuropathic pain: participation of nitric oxide and TNF‐alpha
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Does the lens serve as a ‘sink’ for iron during ocular inflammation?
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Phosphorus nuclear magnetic resonance and ocular metabolism
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A role of PIEZO1 in iron metabolism in mice and humans
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Advanced glycation endproducts—role in pathology of diabetic complications
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Iron metabolism in the eye: A review
inferredcites →https://doi.org/10.1016/j.exer.2019.107862openalex-snapshot
Hydrotropic function of ATP in the crystalline lens
inferredcites →https://doi.org/10.1016/j.exer.2019.107900openalex-snapshot
Piezo channel plays a part in retinal ganglion cell damage
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2016.07.016openalex-snapshot
Mitochondrial oxygen metabolism in primary human lens epithelial cells: Association with age, diabetes and glaucoma
inferredcites →https://doi.org/10.1016/j.imbio.2010.05.025openalex-snapshot
IL-10 regulation of macrophage VEGF production is dependent on macrophage polarisation and hypoxia
inferredcites →https://doi.org/10.1016/j.jconrel.2022.12.012openalex-snapshot
Nanocurcumin combined with insulin alleviates diabetic kidney disease through P38/P53 signaling axis
inferredcites →https://doi.org/10.1016/j.ophtha.2021.04.027openalex-snapshot
Global Prevalence of Diabetic Retinopathy and Projection of Burden through 2045
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Vascular endothelial growth factor in eye disease
inferredcites →https://doi.org/10.1016/j.semcdb.2017.06.018openalex-snapshot
How cells channel their stress: Interplay between Piezo1 and the cytoskeleton
inferredcites →https://doi.org/10.1016/j.taap.2014.12.003openalex-snapshot
Curcumin enhances recovery of pancreatic islets from cellular stress induced inflammation and apoptosis in diabetic rats
inferredcites →https://doi.org/10.1016/j.xinn.2021.100141openalex-snapshot
clusterProfiler 4.0: A universal enrichment tool for interpreting omics data
inferredcites →https://doi.org/10.1016/s0002-9394(14)71857-4openalex-snapshot
Progression of Nonproliferative Diabetic Retinopathy and Visual Outcome After Extracapsular Cataract Extraction and Intraocular Lens Implantation
inferredcites →https://doi.org/10.1016/s0140-6736(21)01919-xopenalex-snapshot
Obesity management as a primary treatment goal for type 2 diabetes: time to reframe the conversation
inferredcites →https://doi.org/10.1016/s0140-6736(21)02247-9openalex-snapshot
A century past the discovery of insulin: global progress and challenges for type 1 diabetes among children and adolescents in low-income and middle-income countries
inferredcites →https://doi.org/10.1016/s2214-109x(20)30489-7openalex-snapshot
Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for the Global Burden of Disease Study
inferredcites →https://doi.org/10.1021/acs.jafc.2c00817openalex-snapshot
Targeting Glucose Transport Proteins for Diabetes Management: Regulatory Roles of Food-Derived Compounds
inferredcites →https://doi.org/10.1021/acs.molpharmaceut.2c00465openalex-snapshot
Oral Nanocurcumin Alone or in Combination with Insulin Alleviates STZ-Induced Diabetic Neuropathy in Rats
inferredcites →https://doi.org/10.1021/acschemneuro.1c00692openalex-snapshot
Paclitaxel and Urolithin A Prevent Histamine-Induced Neurovascular Breakdown Alike, in an Ex Vivo Rat Eye Model
inferredcites →https://doi.org/10.1023/a:1011027328795openalex-snapshot
Pancreatic and hepatic glycogen content in normoglycemic and hyperglycemic rats
inferredcites →https://doi.org/10.1038/s41467-022-31103-yopenalex-snapshot
A critical role of the mechanosensor PIEZO1 in glucose-induced insulin secretion in pancreatic β-cells
inferredcites →https://doi.org/10.1038/s41586-019-1485-8openalex-snapshot
Mechanosensation of cyclical force by PIEZO1 is essential for innate immunity
inferredcites →https://doi.org/10.1038/s41587-019-0201-4openalex-snapshot
Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype
inferredcites →https://doi.org/10.1038/s41598-018-21276-2openalex-snapshot
Iron Overload Accelerates the Progression of Diabetic Retinopathy in Association with Increased Retinal Renin Expression
inferredcites →https://doi.org/10.1039/c8cc10021gopenalex-snapshot
Double-headed nanosystems for oral drug delivery
inferredcites →https://doi.org/10.1042/bcj20160627openalex-snapshot
Protein trafficking in the mitochondrial intermembrane space: mechanisms and links to human disease
inferredcites →https://doi.org/10.1053/gast.2002.33582openalex-snapshot
Differential effects of streptozotocin-induced diabetes on expression of hepatic ABC-transporters in rats
inferredcites →https://doi.org/10.1055/s-2007-1012251openalex-snapshot
Glycaemic Control and Reticulocyte Count in Diabetic Patients
inferredcites →https://doi.org/10.1074/jbc.m115.655555openalex-snapshot
Retinylamine Benefits Early Diabetic Retinopathy in Mice
inferredcites →https://doi.org/10.1093/bioinformatics/btu638openalex-snapshot
HTSeq—a Python framework to work with high-throughput sequencing data
inferredcites →https://doi.org/10.1093/gigascience/giab008openalex-snapshot
Twelve years of SAMtools and BCFtools
inferredcites →https://doi.org/10.1093/nar/gkab913openalex-snapshot
NPCDR: natural product-based drug combination and its disease-specific molecular regulation
inferredcites →https://doi.org/10.1093/nar/gky1131openalex-snapshot
STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
inferredcites →https://doi.org/10.1101/cshperspect.a006411openalex-snapshot
Antiangiogenic Therapy for Ischemic Retinopathies
inferredcites →https://doi.org/10.1101/gr.1239303openalex-snapshot
Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction Networks
inferredcites →https://doi.org/10.1111/bph.13816openalex-snapshot
Nano‐curcumin safely prevents streptozotocin‐induced inflammation and apoptosis in pancreatic beta cells for effective management of Type 1 diabetes mellitus
inferredcites →https://doi.org/10.1111/j.1464-5491.2009.02839.xopenalex-snapshot
Abnormal liver function tests in patients with Type 1 diabetes mellitus: prevalence, clinical correlations and underlying pathologies
inferredcites →https://doi.org/10.1126/sciadv.aau9940openalex-snapshot
Iron is neurotoxic in retinal detachment and transferrin confers neuroprotection
inferredcites →https://doi.org/10.1126/sciadv.abb7878openalex-snapshot
Systemic anti-inflammatory therapy aided by double-headed nanoparticles in a canine model of acute intraocular inflammation
inferredcites →https://doi.org/10.1126/science.aaf6846openalex-snapshot
ATP as a biological hydrotrope
inferredcites →https://doi.org/10.1126/sciimmunol.abb5168openalex-snapshot
Targeting Piezo1 unleashes innate immunity against cancer and infectious disease
inferredcites →https://doi.org/10.1126/scitranslmed.abk1707openalex-snapshot
PIEZO1 mediates a mechanothrombotic pathway in diabetes
inferredcites →https://doi.org/10.1152/ajpendo.00285.2017openalex-snapshot
Curcumin and other dietary polyphenols: potential mechanisms of metabolic actions and therapy for diabetes and obesity
inferredcites →https://doi.org/10.1152/ajpregu.00294.2018openalex-snapshot
Exaggerated mechanoreflex in early-stage type 1 diabetic rats: role of Piezo channels
inferredcites →https://doi.org/10.1155/2010/608751openalex-snapshot
Diabetic Cataract—Pathogenesis, Epidemiology and Treatment
inferredcites →https://doi.org/10.1167/iovs.04-0860openalex-snapshot
Expression of Acute-Phase Response Proteins in Retinal Muller Cells in Diabetes
inferredcites →https://doi.org/10.1172/jci.insight.126747openalex-snapshot
Blood-retina barrier failure and vision loss in neuron-specific degeneration
inferredcites →https://doi.org/10.1172/jci.insight.93751openalex-snapshot
Diabetic retinopathy: current understanding, mechanisms, and treatment strategies
inferredcites →https://doi.org/10.1177/1535370218761662openalex-snapshot
Targeting dysfunctional beta-cell signaling for the potential treatment of type 1 diabetes mellitus
inferredcites →https://doi.org/10.1186/s12886-018-0886-zopenalex-snapshot
Microglia enhanced the angiogenesis, migration and proliferation of co-cultured RMECs
inferredcites →https://doi.org/10.1186/s13059-014-0550-8openalex-snapshot
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
inferredcites →https://doi.org/10.1210/jc.2013-3731openalex-snapshot
Islet Number Rather Than Islet Size Is a Major Determinant of β- and α-Cell Mass in Humans
inferredcites →https://doi.org/10.1371/journal.pbio.3000750openalex-snapshot
Mechanosensitivity is an essential component of phototransduction in vertebrate rods
inferredcites →https://doi.org/10.1371/journal.pone.0036949openalex-snapshot
IL-1β Is Upregulated in the Diabetic Retina and Retinal Vessels: Cell-Specific Effect of High Glucose and IL-1β Autostimulation
inferredcites →https://doi.org/10.1371/journal.pone.0078217openalex-snapshot
Efficacy of Biodegradable Curcumin Nanoparticles in Delaying Cataract in Diabetic Rat Model
inferredcites →https://doi.org/10.1371/journal.pone.0156346openalex-snapshot
Short- and Longterm Glycemic Control of Streptozotocin-Induced Diabetic Rats Using Different Insulin Preparations
inferredcites →https://doi.org/10.1586/eop.13.17openalex-snapshot
Targeting neovascularization in ischemic retinopathy: recent advances
inferredcites →https://doi.org/10.2147/dddt.s79885openalex-snapshot
Impact of streptozotocin on altering normal glucose homeostasis during insulin testing in diabetic rats compared to normoglycemic rats
inferredcites →https://doi.org/10.2174/1381612825666190130140717openalex-snapshot
Current and Future Pharmacologic Therapies for Diabetic Retinopathy
inferredcites →https://doi.org/10.2337/db08-0762openalex-snapshot
Rho Kinase Inhibition by Fasudil Ameliorates Diabetes-Induced Microvascular Damage
inferredcites →https://doi.org/10.2337/db11-0786openalex-snapshot
In Situ Electrophysiological Examination of Pancreatic α Cells in the Streptozotocin-Induced Diabetes Model, Revealing the Cellular Basis of Glucagon Hypersecretion
inferredcites →https://doi.org/10.2337/db13-1195openalex-snapshot
Hepcidin Is Directly Regulated by Insulin and Plays an Important Role in Iron Overload in Streptozotocin-Induced Diabetic Rats
inferredcites →https://doi.org/10.2337/db20-1185openalex-snapshot
Uncovering Pathways to Personalized Therapies in Type 1 Diabetes
inferredcites →https://doi.org/10.3109/08820538.2014.959197openalex-snapshot
Cataract Surgery and its Complications in Diabetic Patients
inferredcites →https://doi.org/10.3389/fendo.2017.00236openalex-snapshot
High Liver Enzyme Concentrations are Associated with Higher Glycemia, but not with Glycemic Variability, in Individuals without Diabetes Mellitus
inferredcites →https://doi.org/10.3389/fphys.2021.689429openalex-snapshot
Interleukin-6 Trans-signaling: A Pathway With Therapeutic Potential for Diabetic Retinopathy
inferredcites →https://doi.org/10.7554/elife.00324openalex-snapshot
Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1
inferredcites →https://doi.org/10.7554/elife.13828openalex-snapshot
Blockade of glucagon signaling prevents or reverses diabetes onset only if residual β-cells persist
inferredcites →https://doi.org/10.7759/cureus.13070openalex-snapshot
Evaluation of Serum Ceruloplasmin Levels as a Biomarker for Oxidative Stress in Patients With Diabetic Retinopathy

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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