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Bioactivity-Guided Navigation of Chemical Space
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/adsc.200800154openalex-snapshot
Solid‐Phase Synthesis of [5.5]‐Spiroketals
inferredcites →https://doi.org/10.1002/anie.200352582openalex-snapshot
Synthesis and Biological Evaluation of an Indomethacin Library Reveals a New Class of Angiogenesis‐Related Kinase Inhibitors
inferredcites →https://doi.org/10.1002/anie.200353609openalex-snapshot
Asymmetric Solid‐Phase Synthesis of 6,6‐Spiroketals
inferredcites →https://doi.org/10.1002/anie.200602125openalex-snapshot
Protein Structure Similarity Clustering: Dynamic Treatment of PDB Structures Facilitates Clustering
inferredcites →https://doi.org/10.1002/anie.200703073openalex-snapshot
Towards the Optimal Screening Collection: A Synthesis Strategy
inferredcites →https://doi.org/10.1002/anie.200801566openalex-snapshot
Discovery of a New Class of Inhibitors of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B by Biology‐Oriented Synthesis
inferredcites →https://doi.org/10.1002/anie.200803437openalex-snapshot
Synthesis of Natural Product Inspired Compound Collections
inferredcites →https://doi.org/10.1002/anie.200902023openalex-snapshot
The Ras Pathway Modulator Melophlin A Targets Dynamins
inferredcites →https://doi.org/10.1002/asia.200700125openalex-snapshot
Identification of Inhibitors for Mycobacterial Protein Tyrosine Phosphatase B (MptpB) by Biology‐Oriented Synthesis (BIOS)
inferredcites →https://doi.org/10.1002/cbic.200700558openalex-snapshot
Indoloquinolizidine Derivatives as Novel and Potent Apoptosis Inducers and Cell‐Cycle Blockers
inferredcites →https://doi.org/10.1002/chem.200601698openalex-snapshot
Biology‐Oriented Synthesis of Stereochemically Diverse Natural‐Product‐Derived Compound Collections by Iterative Allylations on a Solid Support
inferredcites →https://doi.org/10.1002/chem.200901797openalex-snapshot
Biology‐Oriented Combined Solid‐ and Solution‐Phase Synthesis of a Macroline‐Like Compound Collection
inferredcites →https://doi.org/10.1002/cmdc.200800265openalex-snapshot
Natural‐Product‐Like Spiroketals and Fused Bicyclic Acetals as Potential Therapeutic Agents for B‐Cell Chronic Lymphocytic Leukaemia
inferredcites →https://doi.org/10.1002/cmdc.200900469openalex-snapshot
From Machine Learning to Natural Product Derivatives that Selectively Activate Transcription Factor PPARγ
inferredcites →https://doi.org/10.1002/ejoc.200500605openalex-snapshot
Natural Product‐Guided Synthesis of a Spiroacetal Collection Reveals Modulators of Tubulin Cytoskeleton Integrity
inferredcites →https://doi.org/10.1002/med.10059openalex-snapshot
Recent advances in selective opioid receptor agonists and antagonists
inferredcites →https://doi.org/10.1006/jmbi.1998.2043openalex-snapshot
Supersites within superfolds. Binding site similarity in the absence of homology 1 1Edited by J. Thornton
inferredcites →https://doi.org/10.1016/j.cbpa.2005.04.003openalex-snapshot
Wanted: new multicomponent reactions for generating libraries of polycyclic natural products
inferredcites →https://doi.org/10.1016/j.chembiol.2007.02.008openalex-snapshot
Natural Product-Derived Modulators of Cell Cycle Progression and Viral Entry by Enantioselective Oxa Diels-Alder Reactions on the Solid Phase
inferredcites →https://doi.org/10.1016/j.drudis.2006.05.012openalex-snapshot
Virtual ligand screening: strategies, perspectives and limitations
inferredcites →https://doi.org/10.1016/j.drudis.2006.10.005openalex-snapshot
Similarity-based virtual screening using 2D fingerprints
inferredcites →https://doi.org/10.1016/j.jmb.2006.04.024openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.tet.2008.02.106openalex-snapshot
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inferredcites →https://doi.org/10.1021/ci600338xopenalex-snapshot
The Scaffold Tree − Visualization of the Scaffold Universe by Hierarchical Scaffold Classification
inferredcites →https://doi.org/10.1021/cr800188vopenalex-snapshot
Advances in Solution- and Solid-Phase Synthesis toward the Generation of Natural Product-like Libraries
inferredcites →https://doi.org/10.1021/jm00120a002openalex-snapshot
Methods for drug discovery: development of potent, selective, orally effective cholecystokinin antagonists
inferredcites →https://doi.org/10.1021/jm801514wopenalex-snapshot
Novel Chemical Space Exploration via Natural Products
inferredcites →https://doi.org/10.1021/np050229yopenalex-snapshot
A Common Protein Fold Topology Shared by Flavonoid Biosynthetic Enzymes and Therapeutic Targets
inferredcites →https://doi.org/10.1021/np068054vopenalex-snapshot
Natural Products as Sources of New Drugs over the Last 25 Years
inferredcites →https://doi.org/10.1038/nature03001openalex-snapshot
Finishing the euchromatic sequence of the human genome
inferredcites →https://doi.org/10.1038/nature03193openalex-snapshot
Navigating chemical space for biology and medicine
inferredcites →https://doi.org/10.1038/nature05981openalex-snapshot
Structure-based activity prediction for an enzyme of unknown function
inferredcites →https://doi.org/10.1038/nchembio.180openalex-snapshot
Quantifying biogenic bias in screening libraries
inferredcites →https://doi.org/10.1038/nchembio.187openalex-snapshot
Interactive exploration of chemical space with Scaffold Hunter
inferredcites →https://doi.org/10.1038/nchembio.188openalex-snapshot
Bioactivity-guided mapping and navigation of chemical space
inferredcites →https://doi.org/10.1038/nchembio.362openalex-snapshot
Small-molecule inhibition of APT1 affects Ras localization and signaling
inferredcites →https://doi.org/10.1038/nchembio1108-643openalex-snapshot
Reverse engineering intracellular biochemical networks
inferredcites →https://doi.org/10.1039/b717635jopenalex-snapshot
Reagent-controlled domino synthesis of skeletally-diverse compound collections
inferredcites →https://doi.org/10.1073/pnas.0404719101openalex-snapshot
Compound library development guided by protein structure similarity clustering and natural product structure
inferredcites →https://doi.org/10.1073/pnas.0503647102openalex-snapshot
Charting biologically relevant chemical space: A structural classification of natural products (SCONP)
inferredcites →https://doi.org/10.1073/pnas.0601490103openalex-snapshot
Discovery of protein phosphatase inhibitor classes by biology-oriented synthesis
inferredcites →https://doi.org/10.1186/1472-6807-6-6openalex-snapshot
Exploring dynamics of protein structure determination and homology-based prediction to estimate the number of superfamilies and folds
inferredcites →https://doi.org/10.2533/chimia.2007.355openalex-snapshot
Cheminformatic Analysis of Natural Products and their Chemical Space
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Incoming claims: where this work appears in other papers’ reference lists and arguments.
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inferred← citeshttps://doi.org/10.1002/anie.201106249openalex-snapshot
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Highly Enantioselective Catalytic [6+3] Cycloadditions of Azomethine Ylides
inferred← citeshttps://doi.org/10.1002/anie.201208749openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.chembiol.2018.11.014openalex-snapshot
The Pseudo Natural Product Myokinasib Is a Myosin Light Chain Kinase 1 Inhibitor with Unprecedented Chemotype
inferred← citeshttps://doi.org/10.1016/j.ejmcr.2024.100216openalex-snapshot
Delivery of N-heterocyclic drugs, acids, phenols, and thiols via Tailor−made Self−immolative linkers
inferred← citeshttps://doi.org/10.1016/j.ejmech.2019.111981openalex-snapshot
Efficient identification of novel anti-glioma lead compounds by machine learning models
inferred← citeshttps://doi.org/10.1016/j.gresc.2022.09.003openalex-snapshot
Rapid assembly of 1,3-indanedione-based spirocyclic tetrahydroquinolines for inducing human lung cancer cell apoptosis
inferred← citeshttps://doi.org/10.1016/j.ijpddr.2017.02.002openalex-snapshot
4-Nitro styrylquinoline is an antimalarial inhibiting multiple stages of Plasmodium falciparum asexual life cycle
inferred← citeshttps://doi.org/10.1016/j.jmgm.2017.06.019openalex-snapshot
Chemical structure and correlation analysis of HIV-1 NNRT and NRT inhibitors and database-curated, published inhibition constants with chemical structure in diverse datasets
inferred← citeshttps://doi.org/10.1016/j.tet.2011.04.056openalex-snapshot
Enantioselective synthesis of the spirotryprostatin A scaffold
inferred← citeshttps://doi.org/10.1016/j.tet.2014.03.031openalex-snapshot
Diastereoselective one-pot synthesis of novel ABCD-fused chromeno[2,3-d]pyrazolo[3,4-b]pyridines
inferred← citeshttps://doi.org/10.1016/j.tet.2020.131678openalex-snapshot
DMAP-catalyzed decarboxylative [3+2] cycloadditions: A strategy for diastereoselective synthesis of trifluoromethylated chromanone-fused pyrrolidinyl spirooxindoles
inferred← citeshttps://doi.org/10.1016/j.tetasy.2016.05.003openalex-snapshot
Enantiopure hydroxymethylated cycloalkenols as privileged small molecular multifunctional scaffolds for the asymmetric synthesis of carbocycles
inferred← citeshttps://doi.org/10.1016/j.tetlet.2011.01.036openalex-snapshot
Concise, regiocontrolled synthesis of yangjinhualine A
inferred← citeshttps://doi.org/10.1016/j.tetlet.2015.01.021openalex-snapshot
One-pot synthesis of a natural product inspired pyrrolocoumarine compound collection by means of an intramolecular 1,3-dipolar cycloaddition as key step
inferred← citeshttps://doi.org/10.1016/j.tetlet.2017.12.081openalex-snapshot
Asymmetric organocatalytic direct Mannich reaction of acetylacetone and isatin derived ketimines: Low catalyst loading in chiral cinchona-squaramides
inferred← citeshttps://doi.org/10.1016/j.xcrm.2026.102833openalex-snapshot
Fungal metabolite-based immunotherapy overcomes tumor-associated macrophage immunosuppression
inferred← citeshttps://doi.org/10.1016/s1872-2067(23)64510-3openalex-snapshot
Regioselective electrochemical oxidative radical ortho-(4 + 2)/ipso-(3 + 2) cyclization
inferred← citeshttps://doi.org/10.1021/acs.accounts.6c00382openalex-snapshot
Synthetic Framework Evolution: A Scaffold-Centric Perspective on Iterative Chemical Space Expansion
inferred← citeshttps://doi.org/10.1021/acs.jcim.8b00302openalex-snapshot
Characterization of the Chemical Space of Known and Readily Obtainable Natural Products
inferred← citeshttps://doi.org/10.1021/acs.jcim.9b00557openalex-snapshot
Method for Systematic Analogue Search Using the Mega SAR Matrix Database
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.5b00910openalex-snapshot
Scaffold Diversity Inspired by the Natural Product Evodiamine: Discovery of Highly Potent and Multitargeting Antitumor Agents
inferred← citeshttps://doi.org/10.1021/acs.joc.5c02646openalex-snapshot
Natural Biodegradable Lemon Juice-Catalyzed One-Pot Pseudo-Four-Component Synthesis of Functionally Rich 4,5-Dihydro-1 H -pyrrol-5-ols and 1,4-Dihydropyridines: Quantity of Reaction Components and Their Addition Sequence Determine Selectivity Switch between Five- vs Six-Membered Rings
inferred← citeshttps://doi.org/10.1021/acs.joc.9b02633openalex-snapshot
Controlled Evolution of the Cope Rearrangement: Transition from Concerted to Interrupted and Aborted Pericyclic Reactions Regulated by a Switch Built from an Intramolecular Frustrated Lewis Pair
inferred← citeshttps://doi.org/10.1021/acs.orglett.5c00277openalex-snapshot
Stereoselective Synthesis of Biology-Oriented Pentacyclic Pyrrolo[2,1- a ]isoquinoline Scaffolds by Photoredox-Induced Radical Annulations
inferred← citeshttps://doi.org/10.1021/acs.orglett.6b01030openalex-snapshot
Asymmetric Roadmap to Diverse Polycyclic Benzopyrans via Phosphine-Catalyzed Enantioselective [4 + 2]-Annulation Reaction
inferred← citeshttps://doi.org/10.1021/acs.orglett.8b00175openalex-snapshot
Organocatalytic Oxa-Michael/Michael/Michael/Aldol Condensation Quadruple Domino Sequence: Asymmetric Synthesis of Tricyclic Chromanes
inferred← citeshttps://doi.org/10.1021/acs.orglett.8b00382openalex-snapshot
Stereoselective Synthesis of Functionalized Benzooxazepino[5,4-a]isoindolone Derivatives via Cesium Carbonate Catalyzed Formal [5 + 2] Annulation of 2-(2-Hydroxyphenyl)isoindoline-1,3-dione with Allenoates
inferred← citeshttps://doi.org/10.1021/acs.orglett.8b03118openalex-snapshot
Three-Component Reactions to Spirocyclic Pyrrolidinonylformimidamides: α-Isocyano Lactams as Two-Atom Unit in Silver-Catalyzed Formal [3 + 2] Cycloaddition Reactions
inferred← citeshttps://doi.org/10.1021/acs.orglett.9b00139openalex-snapshot
Stereocontrolled Synthesis of Bispirooxindole-Based Hexahydroxanthones with Five Contiguous Stereocenters
inferred← citeshttps://doi.org/10.1021/acscentsci.5c00332openalex-snapshot
Asymmetric Total Synthesis of 4,9,10-Trihydroxyguaia-11(13)en-12,6-olide and Discovery of Its Anticancer Activity against Atypical Teratoid Rhabdoid Tumor
inferred← citeshttps://doi.org/10.1021/acscombsci.7b00038openalex-snapshot
“In Water”: Organocatalyzed Diastereoselective Multicomponent Reactions toward 2-Azapyrrolizidine Alkaloid Scaffolds
inferred← citeshttps://doi.org/10.1021/ar100106nopenalex-snapshot
Chemically Engineered Extracts: Source of Bioactive Compounds
inferred← citeshttps://doi.org/10.1021/ar400286bopenalex-snapshot
Catalytic Enantioselective 1,3-Dipolar Cycloadditions of Azomethine Ylides for Biology-Oriented Synthesis
inferred← citeshttps://doi.org/10.1021/cn3000422openalex-snapshot
Exploring Chemical Space for Drug Discovery Using the Chemical Universe Database
inferred← citeshttps://doi.org/10.1021/cr200164yopenalex-snapshot
Cyclizations of Alkynes: Revisiting Baldwin’s Rules for Ring Closure
inferred← citeshttps://doi.org/10.1021/cr400442vopenalex-snapshot
Development of a Natural-Product-Derived Chemical Toolbox for Modulation of Protein Function
inferred← citeshttps://doi.org/10.1021/cr400698copenalex-snapshot
Modulators of Protein–Protein Interactions
inferred← citeshttps://doi.org/10.1021/ja200374qopenalex-snapshot
Generation of Anti-trypanosomal Agents through Concise Synthesis and Structural Diversification of Sesquiterpene Analogues
inferred← citeshttps://doi.org/10.1021/ja203191fopenalex-snapshot
Rules for Anionic and Radical Ring Closure of Alkynes
inferred← citeshttps://doi.org/10.1021/ja505861dopenalex-snapshot
Biology-Oriented Synthesis: Harnessing the Power of Evolution
inferred← citeshttps://doi.org/10.1021/jacs.1c11270openalex-snapshot
Chemical Evolution of Natural Product Structure
inferred← citeshttps://doi.org/10.1021/jacs.2c02004openalex-snapshot
Access to Cyclic N -Trifluoromethyl Ureas through Photocatalytic Activation of Carbamoyl Azides
inferred← citeshttps://doi.org/10.1021/jacs.4c13538openalex-snapshot
Catalytic Asymmetric Cycloaddition of Olefins with In Situ Generated N-Boc-Formaldimine
inferred← citeshttps://doi.org/10.1021/jm1011116openalex-snapshot
Design and Evaluation of Fragment-Like Estrogen Receptor Tetrahydroisoquinoline Ligands from a Scaffold-Detection Approach
inferred← citeshttps://doi.org/10.1021/jm300288gopenalex-snapshot
Charting, Navigating, and Populating Natural Product Chemical Space for Drug Discovery
inferred← citeshttps://doi.org/10.1021/ol200389popenalex-snapshot
Natural Product Biosynthesis Inspired Concise and Stereoselective Synthesis of Benzopyrones and Related Scaffolds
inferred← citeshttps://doi.org/10.1021/ol302355wopenalex-snapshot
Diastereoselective Multicomponent Reaction in Water: Synthesis of 2-Azapyrrolizidine Alkaloid Analogues
inferred← citeshttps://doi.org/10.1021/sb300080topenalex-snapshot
Modular Construction of a Functional Artificial Epothilone Polyketide Pathway
inferred← citeshttps://doi.org/10.1038/nchem.1506openalex-snapshot
Natural-product-derived fragments for fragment-based ligand discovery
inferred← citeshttps://doi.org/10.1038/nchem.2095openalex-snapshot
Revealing the macromolecular targets of complex natural products
inferred← citeshttps://doi.org/10.1038/nchem.2479openalex-snapshot
Counting on natural products for drug design
inferred← citeshttps://doi.org/10.1038/nchembio.758openalex-snapshot
Natural product–inspired cascade synthesis yields modulators of centrosome integrity
inferred← citeshttps://doi.org/10.1038/s41467-022-28098-xopenalex-snapshot
A general synthesis of azetidines by copper-catalysed photoinduced anti-Baldwin radical cyclization of ynamides
inferred← citeshttps://doi.org/10.1038/s41589-022-01234-wopenalex-snapshot
Modeling the expansion of virtual screening libraries
inferred← citeshttps://doi.org/10.1038/s42004-022-00807-zopenalex-snapshot
Switchable synthesis of natural-product-like lawsones and indenopyrazoles through regioselective ring-expansion of indantrione
inferred← citeshttps://doi.org/10.1039/c1cc11388gopenalex-snapshot
Synthesis of the B-seco limonoid scaffold
inferred← citeshttps://doi.org/10.1039/c1cc14042fopenalex-snapshot
A design strategy for drug-like polyheterocycles with privileged substructures for discovery of specific small-molecule modulators
inferred← citeshttps://doi.org/10.1039/c2sc20096aopenalex-snapshot
Asymmetric Diels–Alder reaction of β,β-disubstituted enals and chromone-fused dienes: construction of collections with high molecular complexity and skeletal diversity
inferred← citeshttps://doi.org/10.1039/c3cc43824dopenalex-snapshot
Catalytic asymmetric exo-selective [6+3] cycloaddition of iminoesters with fulvenes
inferred← citeshttps://doi.org/10.1039/c4cc08555hopenalex-snapshot
Phosphine-catalyzed dearomatizing [3+2] annulations of isoquinolinium methylides with allenes
inferred← citeshttps://doi.org/10.1039/c4ra15164jopenalex-snapshot
Biology-oriented development of novel lipophilic antioxidants with neuroprotective activity
inferred← citeshttps://doi.org/10.1039/c4sc01654hopenalex-snapshot
DNA display of fragment pairs as a tool for the discovery of novel biologically active small molecules
inferred← citeshttps://doi.org/10.1039/c5cc01555copenalex-snapshot
A general catalytic reaction sequence to access alkaloid-inspired indole polycycles
inferred← citeshttps://doi.org/10.1039/c5cc05699copenalex-snapshot
The discovery of novel antifungal scaffolds by structural simplification of the natural product sampangine
inferred← citeshttps://doi.org/10.1039/c5cs00252dopenalex-snapshot
State-of-the-art strategies for targeting protein–protein interactions by small-molecule inhibitors
inferred← citeshttps://doi.org/10.1039/c6ra11543hopenalex-snapshot
Green chemistry oriented multi-component strategy to hybrid heterocycles
inferred← citeshttps://doi.org/10.1039/c6ra12387bopenalex-snapshot
l -Isoleucine derived bifunctional phosphine catalyses asymmetric [3 + 2]-annulation of allenyl-esters and -ketones with ketimines
inferred← citeshttps://doi.org/10.1039/c8ob00233aopenalex-snapshot
A distinctive transformation based diversity oriented synthesis of small ring carbocycles and heterocycles from biocatalytically derived enantiopure α-substituted-β-hydroxyesters
inferred← citeshttps://doi.org/10.1039/c8ob01456fopenalex-snapshot
(−)-Cytisine: Access to a stereochemically defined and functionally flexible piperidine scaffold
inferred← citeshttps://doi.org/10.1039/c8ob01557kopenalex-snapshot
Metal-free multicomponent cascade reactions of homopropargylic amines and acyl chlorides as well as potassium thiocyanate and diiodine: an access to thiazine imides
inferred← citeshttps://doi.org/10.1039/c8ob01946kopenalex-snapshot
Synthesis of functionalized 2,5-dihydropyrrole derivatives via a convenient [3 + 2] annulation of azomethine ylides with allenoates
inferred← citeshttps://doi.org/10.1039/c8ob02620copenalex-snapshot
Cascade reaction based synthetic strategies targeting biologically intriguing indole polycycles
inferred← citeshttps://doi.org/10.1039/c8qo01222aopenalex-snapshot
Thermal-mediated catalyst-free heterolytic cleavage of 3-halooxindoles: rapid access to 3-functionalized-2-oxindoles
inferred← citeshttps://doi.org/10.1039/c9ob00615jopenalex-snapshot
Making endo-cyclizations favorable again: a conceptually new synthetic approach to benzotriazoles via azide group directed lithiation/cyclization of 2-azidoaryl bromides
inferred← citeshttps://doi.org/10.1039/c9ob01203fopenalex-snapshot
Regio- and stereoselective [3 + 2] cycloaddition reaction: access to isoxazole-dispirobisoxindoles featuring three contiguous stereocenters
inferred← citeshttps://doi.org/10.1039/c9ob02193kopenalex-snapshot
Thermal-mediated [1,3]-hydrogen transfer as the key step: access to oxindole–chromone hybrid collection with structural diversity
inferred← citeshttps://doi.org/10.1039/c9qo00127aopenalex-snapshot
Bifunctional oxindole-chromone 4C building block directed asymmetric synthesis of bispirocyclic hexahydroxanthones featuring five contiguous stereocenters and two side-by-side oxindoles
inferred← citeshttps://doi.org/10.1039/c9qo00509aopenalex-snapshot
Synthetic approach to skeletally diverse nitrogen heterocycles from dicyano-2-methylenebut-3-enoates
inferred← citeshttps://doi.org/10.1039/d0cp00253dopenalex-snapshot
Bioactive supra decorated thiazolidine-4-carboxylic acid derivatives attenuate cellular oxidative stress by enhancing catalase activity
inferred← citeshttps://doi.org/10.1039/d0nj02315aopenalex-snapshot
A transition metal-free approach towards the regioselective synthesis of β-carboline tethered pyrroles and 2,3-dihydro-1 H -pyrroles
inferred← citeshttps://doi.org/10.1039/d0np00048eopenalex-snapshot
Bridging the gap between natural product synthesis and drug discovery
inferred← citeshttps://doi.org/10.1039/d0ob01235aopenalex-snapshot
Construction of a meroterpenoid-like compound collection by precursor-assisted biosynthesis
inferred← citeshttps://doi.org/10.1039/d0ra03096aopenalex-snapshot
Isolation and synthesis of cryptosanguinolentine (isocryptolepine), a naturally-occurring bioactive indoloquinoline alkaloid
inferred← citeshttps://doi.org/10.1039/d0ra05105eopenalex-snapshot
Water-triggered union of multi-component reactions towards the synthesis of a 4 H -chromene hybrid scaffold
inferred← citeshttps://doi.org/10.1039/d1nj01159fopenalex-snapshot
A sequential Ugi–Smiles/transition-metal-free endo -dig Conia–ene cyclization: the selective synthesis of saccharin substituted 2,5-dihydropyrroles
inferred← citeshttps://doi.org/10.1039/d1nj02257aopenalex-snapshot
Chromone–indanedione reactant: a bifunctional 3C synthon for diastereoselective construction of skeleton-diversified bispiro-[chromanocyclopentane-oxindole-indanedione]
inferred← citeshttps://doi.org/10.1039/d1nj06112gopenalex-snapshot
3-Vinyl oxindole-chromone synthon as a skeletal reconstruction reactant for the synthesis of 2-hydroxy benzoyl pyridones
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