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Characterization of Mycobacterium tuberculosis NAD Kinase: Functional Analysis of the Full-Length Enzyme by Site-Directed Mutagenesis

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1006/bbrc.2000.3433openalex-snapshot
Inorganic Polyphosphate/ATP-NAD Kinase of Micrococcus flavus and Mycobacterium tuberculosis H37Rv
inferredcites →https://doi.org/10.1006/bbrc.2001.5735openalex-snapshot
Structural and Functional Characterization of Human NAD Kinase
inferredcites →https://doi.org/10.1016/0022-2836(86)90385-2openalex-snapshot
Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes
inferredcites →https://doi.org/10.1016/0022-2836(88)90056-3openalex-snapshot
Crystal structure of the complex of phosphofructokinase from Escherichia coli with its reaction products
inferredcites →https://doi.org/10.1016/s0021-9258(19)43682-xopenalex-snapshot
Pyridine Nucleotide Metabolism in Escherichia coli
inferredcites →https://doi.org/10.1016/s0378-1097(01)00215-4openalex-snapshot
Molecular cloning and identification of UTR1 of a yeast Saccharomyces cerevisiae as a gene encoding an NAD kinase
inferredcites →https://doi.org/10.1046/j.1365-2958.2003.03425.xopenalex-snapshot
Genes required for mycobacterial growth defined by high density mutagenesis
inferredcites →https://doi.org/10.1074/jbc.274.17.11447openalex-snapshot
Mammalian Diacylglycerol Kinases, a Family of Lipid Kinases with Signaling Functions
inferredcites →https://doi.org/10.1074/jbc.m006176200openalex-snapshot
Expression of a Catalytically Inactive Sphingosine Kinase Mutant Blocks Agonist-induced Sphingosine Kinase Activation
inferredcites →https://doi.org/10.1074/jbc.m206687200openalex-snapshot
The Nucleotide-binding Site of Human Sphingosine Kinase 1
inferredcites →https://doi.org/10.1128/jb.169.1.184-188.1987openalex-snapshot
Negative modulation of Escherichia coli NAD kinase by NADPH and NADH
inferredcites →https://doi.org/10.1128/jb.185.16.4844-4850.2003openalex-snapshot
Allosteric Regulation of Bacillus subtilis NAD Kinase by Quinolinic Acid

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4152680openalex-extracted
Identification and Functional Characterization of the NAD Kinase of Leishmania Braziliensis (LbNADK)
inferred← citeshttps://doi.org/10.1002/iub.1277openalex-snapshot
Characterization of a novel mutation in the overlap oftlyAandppnKinvolved in capreomycin resistance inMycobacterium
inferred← citeshttps://doi.org/10.1002/jcp.22419openalex-snapshot
Comparative genomics of NAD(P) biosynthesis and novel antibiotic drug targets
inferred← citeshttps://doi.org/10.1002/prot.21386openalex-snapshot
Characterization of Salmonella typhimurium YegS, a putative lipid kinase homologous to eukaryotic sphingosine and diacylglycerol kinases
inferred← citeshttps://doi.org/10.1007/s00253-010-2481-yopenalex-snapshot
Polyphosphate/ATP-dependent NAD kinase of Corynebacterium glutamicum: biochemical properties and impact of ppnK overexpression on lysine production
inferred← citeshttps://doi.org/10.1007/s00438-005-1113-1openalex-snapshot
Stress induces the expression of AtNADK-1, a gene encoding a NAD(H) kinase in Arabidopsis thaliana
inferred← citeshttps://doi.org/10.1007/s10522-008-9171-5openalex-snapshot
Natural selection and immortality
inferred← citeshttps://doi.org/10.1007/s10930-010-9284-yopenalex-snapshot
Oxidized NADH Oxidase Inhibits Activity of an ATP/NAD Kinase from a Thermophilic Archaeon
inferred← citeshttps://doi.org/10.1007/s11010-011-0838-xopenalex-snapshot
NADPH regulates human NAD kinase, a NADP+-biosynthetic enzyme
inferred← citeshttps://doi.org/10.1016/b978-008045382-8.00138-6openalex-snapshot
Genomics and Enzymology of NAD Biosynthesis
inferred← citeshttps://doi.org/10.1016/j.bbrc.2004.11.163openalex-snapshot
NAD-binding mode and the significance of intersubunit contact revealed by the crystal structure of Mycobacterium tuberculosis NAD kinase–NAD complex
inferred← citeshttps://doi.org/10.1016/j.biochi.2012.09.034openalex-snapshot
Biochemical and functional characterization of novel NADH kinase in the enteric protozoan parasite Entamoeba histolytica
inferred← citeshttps://doi.org/10.1016/j.bios.2014.06.043openalex-snapshot
NADH dehydrogenase-like behavior of nitrogen-doped graphene and its application in NAD+-dependent dehydrogenase biosensing
inferred← citeshttps://doi.org/10.1016/j.bmc.2009.06.013openalex-snapshot
Selective inhibition of nicotinamide adenine dinucleotide kinases by dinucleoside disulfide mimics of nicotinamide adenine dinucleotide analogues
inferred← citeshttps://doi.org/10.1016/j.bmcl.2007.01.012openalex-snapshot
Probing binding requirements of NAD kinase with modified substrate (NAD) analogues
inferred← citeshttps://doi.org/10.1016/j.jmb.2005.09.026openalex-snapshot
Crystal Structures of an NAD Kinase from Archaeoglobus fulgidus in Complex with ATP, NAD, or NADP
inferred← citeshttps://doi.org/10.1016/j.jplph.2016.09.002openalex-snapshot
Metabolomic analysis of NAD kinase-deficient mutants of the cyanobacterium Synechocystis sp. PCC 6803
inferred← citeshttps://doi.org/10.1016/j.procbio.2008.06.011openalex-snapshot
Identification of NADH kinase activity in filamentous fungi and structural modelling of the novel enzyme from Fusarium oxysporum
inferred← citeshttps://doi.org/10.1016/j.redox.2022.102561openalex-snapshot
Molecular properties and regulation of NAD+ kinase (NADK)
inferred← citeshttps://doi.org/10.1016/j.tube.2012.06.002openalex-snapshot
Genetic engineering of Mycobacterium tuberculosis: A review
inferred← citeshttps://doi.org/10.1016/j.ymben.2008.08.008openalex-snapshot
Overexpression of a novel endogenous NADH kinase in Aspergillus nidulans enhances growth
inferred← citeshttps://doi.org/10.1016/s0079-6603(08)00801-5openalex-snapshot
Chapter 1 A Phylogenetic View of Bacterial Ribonucleases
inferred← citeshttps://doi.org/10.1016/s1389-1723(04)00302-0openalex-snapshot
Crystallographic Studies of Mycobacterium tuberculosis Polyphosphate/ATP-NAD Kinase Complexed with NAD
inferred← citeshttps://doi.org/10.1038/ncomms2262openalex-snapshot
Identification and characterization of a human mitochondrial NAD kinase
inferred← citeshttps://doi.org/10.1038/s44321-026-00415-7openalex-snapshot
Integrating chemical, genetic, and feasibility assessments for anti-tubercular target validation
inferred← citeshttps://doi.org/10.1039/c2an16253aopenalex-snapshot
Ultrasensitive detection of the reduced form of nicotinamide adenine dinucleotide based on carbon nanotube field effect transistor
inferred← citeshttps://doi.org/10.1039/d5cs00617aopenalex-snapshot
Antibacterial drug discovery: challenges and preclinical promises from synthetic small molecules
inferred← citeshttps://doi.org/10.1042/bj20061638openalex-snapshot
The power to reduce: pyridine nucleotides – small molecules with a multitude of functions
inferred← citeshttps://doi.org/10.1073/pnas.0602494103openalex-snapshot
Evidence that feedback inhibition of NAD kinase controls responses to oxidative stress
inferred← citeshttps://doi.org/10.1074/jbc.m111.249011openalex-snapshot
Structural Determinants of Discrimination of NAD+ from NADH in Yeast Mitochondrial NADH Kinase Pos5
inferred← citeshttps://doi.org/10.1074/jbc.m406586200openalex-snapshot
A Novel Fold Revealed by Mycobacterium tuberculosis NAD Kinase, a Key Allosteric Enzyme in NADP Biosynthesis
inferred← citeshttps://doi.org/10.1074/jbc.m513919200openalex-snapshot
Synthetic Lethal and Biochemical Analyses of NAD and NADH Kinases in Saccharomyces cerevisiae Establish Separation of Cellular Functions
inferred← citeshttps://doi.org/10.1074/jbc.m701394200openalex-snapshot
NAD Kinases Use Substrate-assisted Catalysis for Specific Recognition of NAD
inferred← citeshttps://doi.org/10.1074/jbc.m800694200openalex-snapshot
Biosynthesis and Recycling of Nicotinamide Cofactors in Mycobacterium tuberculosis
inferred← citeshttps://doi.org/10.1093/abbs/gmp029openalex-snapshot
Molecular properties, functions, and potential applications of NAD kinases
inferred← citeshttps://doi.org/10.1093/femspd/ftab034openalex-snapshot
Conditional impairment of Coxiella burnetii by glucose-6P dehydrogenase activity
inferred← citeshttps://doi.org/10.1093/pcp/pcab023openalex-snapshot
The NAD Kinase Slr0400 Functions as a Growth Repressor in Synechocystis sp. PCC 6803
inferred← citeshttps://doi.org/10.1104/pp.109.140665openalex-snapshot
Pleiotropic Modulation of Carbon and Nitrogen Metabolism in Arabidopsis Plants Overexpressing theNAD kinase2Gene
inferred← citeshttps://doi.org/10.1107/s1744309105019780openalex-snapshot
Structure of a NAD kinase fromThermotoga maritimaat 2.3 Å resolution
inferred← citeshttps://doi.org/10.1111/j.1742-4658.2005.04749.xopenalex-snapshot
Identification of ATP‐NADH kinase isozymes and their contribution to supply of NADP(H) in Saccharomyces cerevisiae
inferred← citeshttps://doi.org/10.1111/tpj.14262openalex-snapshot
One of the NAD kinases, sll1415 , is required for the glucose metabolism of Synechocystis sp. PCC 6803
inferred← citeshttps://doi.org/10.1128/ecosalplus.3.6.3.10openalex-snapshot
Biogenesis and Homeostasis of Nicotinamide Adenine Dinucleotide Cofactor
inferred← citeshttps://doi.org/10.1128/jb.05873-11openalex-snapshot
The Cyanobacterial NAD Kinase Gene sll1415 Is Required for Photoheterotrophic Growth and Cellular Redox Homeostasis in Synechocystis sp. Strain PCC 6803
inferred← citeshttps://doi.org/10.1186/1471-2105-12-s1-s32openalex-snapshot
A study on the flexibility of enzyme active sites
inferred← citeshttps://doi.org/10.1271/bbb.70738openalex-snapshot
Structure and Function of NAD Kinase and NADP Phosphatase: Key Enzymes That Regulate the Intracellular Balance of NAD(H) and NADP(H)
inferred← citeshttps://doi.org/10.1371/journal.pone.0042561openalex-snapshot
The Two PPX-GppA Homologues from Mycobacterium tuberculosis Have Distinct Biochemical Activities
inferred← citeshttps://doi.org/10.1371/journal.pone.0100062openalex-snapshot
Biochemical Characterization of Quinolinic Acid Phosphoribosyltransferase from Mycobacterium tuberculosis H37Rv and Inhibition of Its Activity by Pyrazinamide
inferred← citeshttps://doi.org/10.1371/journal.pone.0101051openalex-snapshot
Genome-Wide Analysis of the NADK Gene Family in Plants
inferred← citeshttps://doi.org/10.2174/092986711795590048openalex-snapshot
NMN/NaMN Adenylyltransferase (NMNAT) and NAD Kinase (NADK) Inhibitors: Chemistry and Potential Therapeutic Applications
inferred← citeshttps://doi.org/10.2183/pjab.97.024openalex-snapshot
Polyphosphate-dependent nicotinamide adenine dinucleotide (NAD) kinase: A novel missing link in human mitochondria
inferred← citeshttps://doi.org/10.3389/fpls.2018.00379openalex-snapshot
NAD Kinases: Metabolic Targets Controlling Redox Co-enzymes and Reducing Power Partitioning in Plant Stress and Development
inferred← citeshttps://doi.org/10.3389/fpls.2019.00847openalex-snapshot
Physiological Significance of NAD Kinases in Cyanobacteria
inferred← citeshttps://doi.org/10.4103/2277-9175.211833openalex-snapshot
Cloning, Expression and Characterization of NAD Kinase from Staphylococcus aureus Involved in the Formation of NADP (H): A Key Molecule in the Maintaining of Redox Status and Biofilm Formation
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