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Conformational Studies of Microcystin-LR Using NMR Spectroscopy and Molecular Dynamics Calculations,
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/jcc.540040211openalex-snapshot
CHARMM : A program for macromolecular energy, minimization, and dynamics calculations
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Co-crystallization of the Catalytic Subunit of the Serine/Threonine Specific Protein Phosphatase 1 from Human in Complex with Microcystin LR
inferredcites →https://doi.org/10.1007/bf00014522openalex-snapshot
Investigation of a toxic water-bloom of Microcystis aeruginosa (Cyanophyceae) in Lake Akersvatn, Norway
inferredcites →https://doi.org/10.1007/bf01629424openalex-snapshot
Liver tumor promotion by the cyanobacterial cyclic peptide toxin microcystin-LR
inferredcites →https://doi.org/10.1007/bf02186070openalex-snapshot
Structure and biosynthesis of toxins from blue-green algae (cyanobacteria)
inferredcites →https://doi.org/10.1016/0014-5793(90)80245-eopenalex-snapshot
Cyanobacterial microcystin‐LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants
inferredcites →https://doi.org/10.1016/0014-5793(94)00382-3openalex-snapshot
Identification of protein phosphatase 2A as the primary target for microcystin‐LR in rat liver homogenates
inferredcites →https://doi.org/10.1016/b978-1-4832-8439-2.50006-7openalex-snapshot
DIMENSIONING OF AERATED GRIT CHAMBERS AND USE AS A HIGHLY LOADED ACTIVATED SLUDGE PROCESS
inferredcites →https://doi.org/10.1016/s0040-4039(00)99357-2openalex-snapshot
Total synthesis of Adda, the unique C20 amino acid of cyanobacterial hepatotoxins
inferredcites →https://doi.org/10.1021/ja00038a054openalex-snapshot
Conformation of cyclic analogs of substance P: NMR and molecular dynamics in dimethyl sulfoxide
inferredcites →https://doi.org/10.1021/jo00029a016openalex-snapshot
Identification of 12 hepatotoxins from a Homer Lake bloom of the cyanobacteria Microcystis aeruginosa, Microcystis viridis, and Microcystis wesenbergii: nine new microcystins
inferredcites →https://doi.org/10.1021/jo00312a019openalex-snapshot
Structures of three new cyclic heptapeptide hepatotoxins produced by the cyanobacterium (blue-green alga) Nostoc sp. strain 152
inferredcites →https://doi.org/10.1093/protein/2.1.27openalex-snapshot
Determination of three-dimensional structures of proteins by simulated annealing with interproton distance restraints. Application to crambin, potato carboxypeptidase inhibitor and barley serine proteinase inhibitor 2
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Toxicity Mechanism of Microcystin-Lr to Lettuce ( Lactuca Sativa L.): Active Transmembrane Transport, Blockage of the Electron Transport Chain, and Reactive Oxygen Species Burst
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Synthesis of Highly Selective Submicromolar Microcystin‐Based Inhibitors of Protein Phosphatase (PP)2A over PP1
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Synthesis of Highly Selective Submicromolar Microcystin‐Based Inhibitors of Protein Phosphatase (PP)2A over PP1
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The cis‐trans isomerization of N‐methyl‐α,β‐dehydroamino acids
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Cytological alterations in isolated hepatocytes from common carp (Cyprinus carpio L.) exposed to microcystin-LR
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Comprehensive study of proteins that interact with microcystin-LR
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Visible-light-driven photocatalytic degradation of microcystin-LR by Bi-doped TiO2
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Visible light-induced N-doped TiO2 nanoparticles for the degradation of microcystin-LR
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The permeability effect of microcystin-RR on Escherichia coli and Bacillus subtilis
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Cyanobacteria and Their Toxins
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Microcystin-LR detection in water by the Fabry–Pérot interferometer using an optical fibre coated with a sol–gel imprinted sensing membrane
inferred← citeshttps://doi.org/10.1016/j.cbi.2021.109766openalex-snapshot
Investigation of microcystin conformation and binding towards PPP1 by molecular dynamics simulation
inferred← citeshttps://doi.org/10.1016/j.cbi.2025.111372openalex-snapshot
Conformation and binding of 12 Microcystin (MC) congeners to PPP1 using molecular dynamics simulations: A potential approach in support of an improved MC risk assessment
inferred← citeshttps://doi.org/10.1016/j.chemosphere.2019.125575openalex-snapshot
Removal of microcystins from a waste stabilisation lagoon: Evaluation of a packed-bed continuous flow TiO2 reactor
inferred← citeshttps://doi.org/10.1016/j.envpol.2004.09.014openalex-snapshot
Tissue distributions and seasonal dynamics of the hepatotoxic microcystins-LR and -RR in a freshwater snail (Bellamya aeruginosa) from a large shallow, eutrophic lake of the subtropical China
inferred← citeshttps://doi.org/10.1016/j.fct.2024.114907openalex-snapshot
Potential (co-)contamination of dairy milk with AFM1 and MC-LR and their synergistic interaction in inducing mitochondrial dysfunction in HepG2 cells
inferred← citeshttps://doi.org/10.1016/j.scp.2016.02.001openalex-snapshot
Theoretical investigation of microcystin-LR, microcystin-RR and nodularin-R complexation with α-, β-, and γ-cyclodextrin as a starting point for the targeted design of efficient cyanotoxin traps
inferred← citeshttps://doi.org/10.1016/j.toxicon.2005.12.006openalex-snapshot
Damage of cell membrane and antioxidative system in human erythrocytes incubated with microcystin-LR in vitro
inferred← citeshttps://doi.org/10.1016/j.toxrep.2015.01.008openalex-snapshot
An overview of the toxic effect of potential human carcinogen Microcystin-LR on testis
inferred← citeshttps://doi.org/10.1016/s0003-2670(97)00131-1openalex-snapshot
Chromatography of microcystins
inferred← citeshttps://doi.org/10.1016/s0009-2797(02)00002-9openalex-snapshot
In vivo assessment of nodularin-induced hepatotoxicity in the rat using magnetic resonance techniques (MRI, MRS and EPR oximetry)
inferred← citeshttps://doi.org/10.1016/s0041-0101(00)00148-3openalex-snapshot
Production and specificity of mono and polyclonal antibodies against microcystins conjugated through N-methyldehydroalanine
inferred← citeshttps://doi.org/10.1016/s0041-0101(01)00104-0openalex-snapshot
Production and specificity of monoclonal antibodies against nodularin conjugated through N-methyldehydrobutyrine
inferred← citeshttps://doi.org/10.1016/s0041-0101(01)00173-8openalex-snapshot
The toxic effects of microcystin-LR on embryo-larval and juvenile development of loach, Misguruns mizolepis Gunthe
inferred← citeshttps://doi.org/10.1016/s0041-0101(97)00102-5openalex-snapshot
the toxicology of microcystins
inferred← citeshttps://doi.org/10.1016/s0301-4622(98)00215-4openalex-snapshot
Influence of 5-bromodeoxycytosine substitution on triplex DNA stability and conformation
inferred← citeshttps://doi.org/10.1016/s0928-0987(00)00116-0openalex-snapshot
A study of the binding requirements of calyculin A and dephosphonocalyculin A with PP1, development of a molecular recognition model for the binding interactions of the okadaic acid class of compounds with PP1
inferred← citeshttps://doi.org/10.1016/s0968-0896(98)00254-5openalex-snapshot
The design, synthesis, and biological evaluation of analogues of the serine-threonine protein phosphatase 1 and 2A selective inhibitor microcystin LA: rational modifications imparting PP1 selectivity
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Chapter 11B Toxins of freshwater cyanobacteria (blue-green algae)
inferred← citeshttps://doi.org/10.1016/s1572-5995(97)80044-0openalex-snapshot
Microcystins and nodularins hepatotoxic cyclic peptides of cyanobacterial origin
inferred← citeshttps://doi.org/10.1021/acs.chemrestox.0c00164openalex-snapshot
Microcystins: Biogenesis, Toxicity, Analysis, and Control
inferred← citeshttps://doi.org/10.1021/acs.est.6b05939openalex-snapshot
Microcystin-LR Binds Iron, and Iron Promotes Self-Assembly
inferred← citeshttps://doi.org/10.1021/acs.est.6c01928openalex-snapshot
Selective Oxidation of Cyanotoxins (Microcystins) by Peroxyacetyl Radical: Kinetic Studies and Mechanistic Considerations
inferred← citeshttps://doi.org/10.1021/acs.jafc.4c12002openalex-snapshot
Novel Insights into Microcystin-LR Uptake, Accumulation, and Toxicity Mechanisms in Lettuce ( Lactuca sativa L.) Using a Protoplast Model
inferred← citeshttps://doi.org/10.1021/acsapm.3c02929openalex-snapshot
Hydrogen Bond-Dominated Hydrogel Copolymers for Selective Isolation and Purification of Microcystin-LR from Microcystis aeruginosa Lysate
inferred← citeshttps://doi.org/10.1021/acsnano.6c05413openalex-snapshot
Sub-Nanomolar Detection and Discrimination of Microcystin Congeners Using Aerolysin Nanopores
inferred← citeshttps://doi.org/10.1021/es048350zopenalex-snapshot
Ultrasonically Induced Degradation and Detoxification of Microcystin-LR (Cyanobacterial Toxin)
inferred← citeshttps://doi.org/10.1021/jm960873xopenalex-snapshot
A Model for Binding of Structurally Diverse Natural Product Inhibitors of Protein Phosphatases PP1 and PP2A
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Isolation and Structure Determination of Two Microcystins and Sequence Comparison of the McyABC Adenylation Domains in Planktothrix Species
inferred← citeshttps://doi.org/10.1039/b920193aopenalex-snapshot
Facile and rapid access to linear and truncated microcystin analogues for the implementation of immunoassays
inferred← citeshttps://doi.org/10.1039/c8ra10384dopenalex-snapshot
Alpha-hemolysin nanopore allows discrimination of the microcystins variants
inferred← citeshttps://doi.org/10.1039/c9nj04678jopenalex-snapshot
Conjugated microporous polymer nanosheets and nanotubes as novel absorbents for microcystin-LR: insights from theoretical investigations
inferred← citeshttps://doi.org/10.1039/d2an01680jopenalex-snapshot
Molecularly imprinted nanoparticle-based assay (MINA) for microcystin-LR detection in water
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Solution Structure of Nodularin
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A Molecular Basis for Different Interactions of Marine Toxins with Protein Phosphatase-1
inferred← citeshttps://doi.org/10.1093/protein/gzaa016openalex-snapshot
Understanding microcystin-LR antibody binding interactions using in silico docking and in vitro mutagenesis
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Cyanobacterial toxins and liver diseaseThis article is one of a selection of papers published in a special issue celebrating the 125th anniversary of the Faculty of Medicine at the University of Manitoba.
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Toxin Chemistry and Biosynthesis
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Toxicological Studies on Microcystin Produced by Microcystis aeruginosa : Assessment and Management
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Reduction of trihalomethane formation and detoxification of microcystins in tap water by ozonation
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Adsorption of Pesticides, Antibiotics and Microcystin-LR by Graphene and Hexagonal Boron Nitride Nano-Systems: A Semiempirical PM7 and Theoretical HSAB Study
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Theoretical Analysis of the Adsorption of Pentachlorophenol and 6-OH-BDE-47 (6-Hydroxy-2,2’,4,4’-Tetrabromodiphenyl Ether) by Boron Nitride Nanotubes Decorated with Double-Decker Lanthanide(III) Phthalocyanine Complexes
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Microcystis aeruginosa: source of toxic microcystins in drinking water
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