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Comprehensive Survey of Chemical Libraries for Drug Discovery and Chemical Biology: 2007

https://doi.org/10.1021/cc800119z
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inferredcites →https://doi.org/10.1002/1521-3773(20011217)40:24<4677::aid-anie4677>3.0.co;2-uopenalex-snapshot
Single-Compound Libraries of Organic Materials: Parallel Synthesis and Screening of Fluorescent Dyes
inferredcites →https://doi.org/10.1002/adsc.200600461openalex-snapshot
Syntheses and Reactivity of Analogues of Grubbs’ Second Generation Metathesis Catalyst with Fluorous Phosphines: A New Phase‐Transfer Strategy for Catalyst Activation
inferredcites →https://doi.org/10.1002/anie.200605190openalex-snapshot
Direct and Label‐Free Detection of Solid‐Phase‐Bound Compounds by Using Surface‐Enhanced Raman Scattering Microspectroscopy
inferredcites →https://doi.org/10.1002/anie.200700008openalex-snapshot
Probing Integrin Selectivity: Rational Design of Highly Active and Selective Ligands for the α5β1 and αvβ3 Integrin Receptor
inferredcites →https://doi.org/10.1002/anie.200700654openalex-snapshot
Isolation of High‐Affinity Trypsin Inhibitors from a DNA‐Encoded Chemical Library
inferredcites →https://doi.org/10.1002/anie.200700762openalex-snapshot
Synthesis of Diverse Lactam Carboxamides Leading to the Discovery of a New Transcription‐Factor Inhibitor
inferredcites →https://doi.org/10.1002/anie.200701434openalex-snapshot
Multistep Continuous‐Flow Microchemical Synthesis Involving Multiple Reactions and Separations
inferredcites →https://doi.org/10.1002/anie.200701603openalex-snapshot
IBX‐Mediated Oxidative Ugi‐Type Multicomponent Reactions: Application to the N and C1 Functionalization of Tetrahydroisoquinoline
inferredcites →https://doi.org/10.1002/anie.200702406openalex-snapshot
Modular Synthesis of Radicicol A and Related Resorcylic Acid Lactones, Potent Kinase Inhibitors
inferredcites →https://doi.org/10.1002/anie.200703208openalex-snapshot
Solid‐Phase Library Synthesis of Polyynes Similar to Natural Products
inferredcites →https://doi.org/10.1002/anie.200703323openalex-snapshot
KNOBLE: A Knowledge‐Based Approach for the Design and Synthesis of Readily Accessible Small‐Molecule Chemical Probes To Test Protein Binding
inferredcites →https://doi.org/10.1002/asia.200600301openalex-snapshot
Donor‐Bound Glycosylation for Various Glycosyl Acceptors: Bidirectional Solid‐Phase Semisynthesis of Vancomycin and Its Derivatives
inferredcites →https://doi.org/10.1002/asia.200700117openalex-snapshot
Design of Binaphthyl‐Modified Symmetrical Chiral Phase‐Transfer Catalysts: Substituent Effect of 4,4′,6,6′‐Positions of Binaphthyl Rings in the Asymmetric Alkylation of a Glycine Derivative
inferredcites →https://doi.org/10.1002/asia.200700125openalex-snapshot
Identification of Inhibitors for Mycobacterial Protein Tyrosine Phosphatase B (MptpB) by Biology‐Oriented Synthesis (BIOS)
inferredcites →https://doi.org/10.1002/cbic.200700403openalex-snapshot
A Small‐Molecule Antagonist of the Hedgehog Signaling Pathway
inferredcites →https://doi.org/10.1002/chem.200601136openalex-snapshot
Latrunculin Analogues with Improved Biological Profiles by “Diverted Total Synthesis”: Preparation, Evaluation, and Computational Analysis
inferredcites →https://doi.org/10.1002/chem.200601429openalex-snapshot
A Fluorous, Pummerer Cyclative‐Capture Strategy for the Synthesis of N‐Heterocycles
inferredcites →https://doi.org/10.1002/chem.200601698openalex-snapshot
Biology‐Oriented Synthesis of Stereochemically Diverse Natural‐Product‐Derived Compound Collections by Iterative Allylations on a Solid Support
inferredcites →https://doi.org/10.1002/cjoc.200790224openalex-snapshot
One‐Pot Synthesis of 1,2,3‐Triazoles using Polymer‐Supported Propyne in Aqueous Solution
inferredcites →https://doi.org/10.1002/cmdc.200600250openalex-snapshot
Combined Mass Spectrometry and Dynamic Chemistry Approach to Identify Metalloenzyme Inhibitors
inferredcites →https://doi.org/10.1002/cmdc.200700022openalex-snapshot
Synthesis, Cruzain Docking, and in vitro Studies of Aryl‐4‐Oxothiazolylhydrazones Against Trypanosoma cruzi
inferredcites →https://doi.org/10.1002/cmdc.200700048openalex-snapshot
HTS, Chemical Hybridization, and Drug Design Identify a Chemically Unique Antituberculosis Agent–Coupling Serendipity and Rational Approaches to Drug Discovery
inferredcites →https://doi.org/10.1002/cmdc.200700067openalex-snapshot
GPCR Targeted Library Design: Novel Dopamine D3 Receptor Ligands
inferredcites →https://doi.org/10.1002/cmdc.200700070openalex-snapshot
Screening of Protease Inhibitors as Antiplasmodial Agents. Part I: Aziridines and Epoxides
inferredcites →https://doi.org/10.1002/cmdc.200700120openalex-snapshot
Rapid Synthesis of Iminosugar Derivatives for Cell‐Based In Situ Screening: Discovery of “Hit” Compounds with Anticancer Activity
inferredcites →https://doi.org/10.1002/ejoc.200600354openalex-snapshot
One‐Step Synthesis of Natural Product‐Inspired Biaryl Ether‐Cyclopeptoid Macrocycles by Double Ugi Multiple‐Component Reactions of Bifunctional Building Blocks
inferredcites →https://doi.org/10.1002/ejoc.200600837openalex-snapshot
Aziridines in Parallel‐ and Solid‐Phase Synthesis
inferredcites →https://doi.org/10.1002/ejoc.200600970openalex-snapshot
Synthesis of Novel Quinone–Amino Acid Hybrids via Cross‐Enyne Metathesis and Diels–Alder Reaction as Key Steps
inferredcites →https://doi.org/10.1002/ejoc.200601060openalex-snapshot
Synthesis of Heterocyclic Systems by Transition‐Metal‐Catalyzed Cyclization‐Migration Reactions – A Diversity‐Oriented Strategy for the Construction of Spirocyclic 3(2 H )‐Furanones and 3‐Pyrrolones
inferredcites →https://doi.org/10.1002/ejoc.200601068openalex-snapshot
Repetitive Application of a Fluorous Chiral BINAP–Ru Complex in the Asymmetric Hydrogenation of Olefins
inferredcites →https://doi.org/10.1002/ejoc.200700263openalex-snapshot
Eight‐Membered‐Ring Lactams – New Scaffolds for Combinatorial Chemistry Prepared by Ring‐Expansion of 1,4‐Diketones with Primary Amines
inferredcites →https://doi.org/10.1002/ejoc.200700287openalex-snapshot
A Palladium/Perfluoroalkylated Pyridine Catalyst for Sonogashira Reaction of Aryl Bromides and Chlorides in a Fluorous Biphasic System
inferredcites →https://doi.org/10.1002/ejoc.200700525openalex-snapshot
Fluorous Synthesis of Yuehchukene by α‐Lithiation of Perfluoroalkyl‐Tagged 1‐(Arylsulfonyl)indole with Mesityllithium
inferredcites →https://doi.org/10.1002/ejoc.200700612openalex-snapshot
Novel 4‐Aminoquinolines through Microwave‐Assisted SNAr Reactions: a Practical Route to Antimalarial Agents
inferredcites →https://doi.org/10.1002/ejoc.200700744openalex-snapshot
Cross‐Enyne and Ring‐Closing Metathesis Cascade: A Building‐Block Approach Suitable for Diversity‐Oriented Synthesis of Densely Functionalized Macroheterocycles with Amino Acid Scaffolds
inferredcites →https://doi.org/10.1002/qsar.200620036openalex-snapshot
Solid‐Phase Synthesis of Aryl‐Alkylamine Derivatives Using Protected Aminoalcohol Building Blocks on SynPhaseTM Lanterns
inferredcites →https://doi.org/10.1007/128_2006_107openalex-snapshot
Combinatorial Solid-Phase Natural Product Chemistry
inferredcites →https://doi.org/10.1007/128_2007_109openalex-snapshot
Probing Biology with Small Molecule Microarrays (SMM)
inferredcites →https://doi.org/10.1007/128_2007_135openalex-snapshot
Solid Phase Chemistry for the Directed Synthesis of Biologically Active Polyamine Analogs, Derivatives, and Conjugates
inferredcites →https://doi.org/10.1007/2789_2006_005openalex-snapshot
Designing Compound Libraries Targeting GPCRs
inferredcites →https://doi.org/10.1007/s10593-007-0025-xopenalex-snapshot
Microwave-promoted automated synthesis of a coumarin library
inferredcites →https://doi.org/10.1007/s11030-007-9055-7openalex-snapshot
A simple approach to the synthesis of highly functionalized 3-alkylidene-2,3-dihydro-1H-pyrrole-2-ol derivatives and related pyrroles
inferredcites →https://doi.org/10.1007/s11030-007-9058-4openalex-snapshot
Synthesis of C-11 modified mifepristone analog libraries
inferredcites →https://doi.org/10.1016/j.bmc.2006.09.034openalex-snapshot
Synthesis of diverse analogues of Oenostacin and their antibacterial activities
inferredcites →https://doi.org/10.1016/j.bmc.2006.09.036openalex-snapshot
A two stage click-based library of protein tyrosine phosphatase inhibitors
inferredcites →https://doi.org/10.1016/j.bmc.2006.09.045openalex-snapshot
Modifications of the pyroglutamic acid and histidine residues in thyrotropin-releasing hormone (TRH) yield analogs with selectivity for TRH receptor type 2 over type 1
inferredcites →https://doi.org/10.1016/j.bmc.2006.09.051openalex-snapshot
Novel T-type calcium channel blockers: Dioxoquinazoline carboxamide derivatives
inferredcites →https://doi.org/10.1016/j.bmc.2006.10.010openalex-snapshot
A library of novel hydroxamic acids targeting the metallo-protease family: Design, parallel synthesis and screening
inferredcites →https://doi.org/10.1016/j.bmc.2006.10.024openalex-snapshot
Solid-phase synthesis of a combinatorial library of dihydroceramide analogues and its activity in human alveolar epithelial cells
inferredcites →https://doi.org/10.1016/j.bmc.2006.10.062openalex-snapshot
Synthesis and evaluation of isosteres of N-methyl indolo[3,2-b]-quinoline (cryptolepine) as new antiinfective agents
inferredcites →https://doi.org/10.1016/j.bmc.2006.10.063openalex-snapshot
Design, synthesis, and antiproliferative and CDK2-cyclin a inhibitory activity of novel flavopiridol analogues
inferredcites →https://doi.org/10.1016/j.bmc.2006.11.003openalex-snapshot
Phenylglycine as a novel P2 scaffold in hepatitis C virus NS3 protease inhibitors
inferredcites →https://doi.org/10.1016/j.bmc.2006.11.004openalex-snapshot
Lead discovery and optimization of T-type calcium channel blockers
inferredcites →https://doi.org/10.1016/j.bmc.2006.11.015openalex-snapshot
Parallel solid synthesis of inhibitors of the essential cell division FtsZ enzyme as a new potential class of antibacterials
inferredcites →https://doi.org/10.1016/j.bmc.2007.01.054openalex-snapshot
Synthesis of a novel C2-aryl pyrrolo[2,1-c][1,4]benzodiazepine-5,11-dione library: Effect of C2-aryl substitution on cytotoxicity and non-covalent DNA binding
inferredcites →https://doi.org/10.1016/j.bmc.2007.02.018openalex-snapshot
Novel class of arylpiperazines containing N-acylated amino acids: Their synthesis, 5-HT1A, 5-HT2A receptor affinity, and in vivo pharmacological evaluation
inferredcites →https://doi.org/10.1016/j.bmc.2007.03.066openalex-snapshot
Prodrug-based design, synthesis, and biological evaluation of N-benzenesulfonylpiperidine derivatives as novel, orally active factor Xa inhibitors
inferredcites →https://doi.org/10.1016/j.bmc.2007.05.029openalex-snapshot
Selection, synthesis, and structure–activity relationship of tetrahydropyrido[4,3-d]pyrimidine-2,4-diones as human GnRH receptor antagonists
inferredcites →https://doi.org/10.1016/j.bmc.2007.05.038openalex-snapshot
Anti-malarial activity of N6-modified purine analogues
inferredcites →https://doi.org/10.1016/j.bmc.2007.06.003openalex-snapshot
Design and synthesis of a library of tertiary amides: Evaluation as mimetics of the melanocortins’ active core
inferredcites →https://doi.org/10.1016/j.bmc.2007.06.016openalex-snapshot
New chemical tools for investigating human mitotic kinesin Eg5
inferredcites →https://doi.org/10.1016/j.bmc.2007.06.053openalex-snapshot
A novel approach to cyclin-dependent kinase 5/p25 inhibitors: A potential treatment for Alzheimer’s disease
inferredcites →https://doi.org/10.1016/j.bmc.2007.07.026openalex-snapshot
Selective angiotensin II AT2 receptor agonists devoid of the imidazole ring system
inferredcites →https://doi.org/10.1016/j.bmc.2007.07.042openalex-snapshot
Antiproliferative activity of chalcones with basic functionalities
inferredcites →https://doi.org/10.1016/j.bmc.2007.07.049openalex-snapshot
Synthesis and biological evaluation of non-peptide αvβ3/α5β1 integrin dual antagonists containing 5,6-dihydropyridin-2-one scaffolds
inferredcites →https://doi.org/10.1016/j.bmc.2007.08.038openalex-snapshot
Click chemistry based solid phase supported synthesis of dopaminergic phenylacetylenes
inferredcites →https://doi.org/10.1016/j.bmcl.2006.04.060openalex-snapshot
Discovery and SAR of 2-amino-5-(thioaryl)thiazoles as potent and selective Itk inhibitors
inferredcites →https://doi.org/10.1016/j.bmcl.2006.08.104openalex-snapshot
Synthesis of thiazolone-based sulfonamides as inhibitors of HCV NS5B polymerase
inferredcites →https://doi.org/10.1016/j.bmcl.2006.10.001openalex-snapshot
Parallel strategies for the preparation and selection of liver-targeted glucocorticoid receptor antagonists
inferredcites →https://doi.org/10.1016/j.bmcl.2006.10.003openalex-snapshot
Discovery of novel phosphorus-containing steroids as selective glucocorticoid receptor antagonist
inferredcites →https://doi.org/10.1016/j.bmcl.2006.10.015openalex-snapshot
Structure–activity relationships of novel non-competitive mGluR1 antagonists: A potential treatment for chronic pain
inferredcites →https://doi.org/10.1016/j.bmcl.2006.10.040openalex-snapshot
Towards erythropoietin mimicking small molecules
inferredcites →https://doi.org/10.1016/j.bmcl.2006.10.042openalex-snapshot
Design, synthesis, and biological evaluation of 1,3-dioxoisoindoline-5-carboxamide derivatives as T-type calcium channel blockers
inferredcites →https://doi.org/10.1016/j.bmcl.2006.10.050openalex-snapshot
Solid phase-assisted synthesis and screening of a small library of N-(4-hydroxyphenyl)retinamide (4-HPR) analogs
inferredcites →https://doi.org/10.1016/j.bmcl.2006.10.058openalex-snapshot
α-Methyltryptamine sulfonamide derivatives as novel glucocorticoid receptor ligands
inferredcites →https://doi.org/10.1016/j.bmcl.2006.10.093openalex-snapshot
Discovery of a new class of 4-anilinopyrimidines as potent c-Jun N-terminal kinase inhibitors: Synthesis and SAR studies
inferredcites →https://doi.org/10.1016/j.bmcl.2006.11.019openalex-snapshot
Potent and selective xanthine-based inhibitors of phosphodiesterase 5
inferredcites →https://doi.org/10.1016/j.bmcl.2006.11.046openalex-snapshot
Inhibition of membrane-associated carbonic anhydrase isozymes IX, XII and XIV with a library of glycoconjugate benzenesulfonamides
inferredcites →https://doi.org/10.1016/j.bmcl.2006.11.081openalex-snapshot
Challenges in the development of mGluR5 positive allosteric modulators: The discovery of CPPHA
inferredcites →https://doi.org/10.1016/j.bmcl.2006.11.085openalex-snapshot
Synthesis and biological evaluation of new conformationally biased integrin ligands based on a tetrahydroazoninone scaffold
inferredcites →https://doi.org/10.1016/j.bmcl.2006.11.090openalex-snapshot
Discovery of 2-iminobenzimidazoles as a new class of trypanothione reductase inhibitor by high-throughput screening
inferredcites →https://doi.org/10.1016/j.bmcl.2006.11.095openalex-snapshot
Structural simplification of bioactive natural products with multicomponent synthesis: Dihydropyridopyrazole analogues of podophyllotoxin
inferredcites →https://doi.org/10.1016/j.bmcl.2006.12.016openalex-snapshot
High-throughput screening affords novel and selective trypanothione reductase inhibitors with anti-trypanosomal activity
inferredcites →https://doi.org/10.1016/j.bmcl.2006.12.049openalex-snapshot
Application of the Suzuki–Miyaura cross-coupling to increase antimicrobial potency generates promising novel antibacterials
inferredcites →https://doi.org/10.1016/j.bmcl.2006.12.062openalex-snapshot
Identification, synthesis, and biological evaluation of novel pyrazoles as low molecular weight luteinizing hormone receptor agonists
inferredcites →https://doi.org/10.1016/j.bmcl.2006.12.066openalex-snapshot
New thiopyrazolo[3,4-d]pyrimidine derivatives as anti-mycobacterial agents
inferredcites →https://doi.org/10.1016/j.bmcl.2006.12.068openalex-snapshot
One-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones using chloroacetic acid as catalyst
inferredcites →https://doi.org/10.1016/j.bmcl.2006.12.083openalex-snapshot
Design and synthesis of novel heterobiaryl amides as metabotropic glutamate receptor subtype 5 antagonists
inferredcites →https://doi.org/10.1016/j.bmcl.2006.12.084openalex-snapshot
Solid phase synthesis and SAR of small molecule agonists for the GPR40 receptor
inferredcites →https://doi.org/10.1016/j.bmcl.2006.12.101openalex-snapshot
Synthesis and biological evaluation of new taxoids derived from 2-deacetoxytaxinine J
inferredcites →https://doi.org/10.1016/j.bmcl.2006.12.103openalex-snapshot
Structure–activity relationship (SAR) studies of quinoxalines as novel HCV NS5B RNA-dependent RNA polymerase inhibitors
inferredcites →https://doi.org/10.1016/j.bmcl.2006.12.110openalex-snapshot
Solid-phase analogue synthesis of caspase-3 inhibitors via palladium-catalyzed amination of 3-bromopyrazinones
inferredcites →https://doi.org/10.1016/j.bmcl.2007.01.021openalex-snapshot
Design and synthesis of β-methoxyacrylate analogues via click chemistry and biological evaluations
inferredcites →https://doi.org/10.1016/j.bmcl.2007.01.026openalex-snapshot
Pyrrolidine-constrained phenethylamines: The design of potent, selective, and pharmacologically efficacious dipeptidyl peptidase IV (DPP4) inhibitors from a lead-like screening hit
inferredcites →https://doi.org/10.1016/j.bmcl.2007.01.046openalex-snapshot
Evaluation of the anti-hepatitis C virus effect of novel potent, selective, and orally bioavailable JNK and VEGFR kinase inhibitors
inferredcites →https://doi.org/10.1016/j.bmcl.2007.01.050openalex-snapshot
CCR5 receptor antagonists: Discovery and SAR of novel 4-hydroxypiperidine derivatives
inferredcites →https://doi.org/10.1016/j.bmcl.2007.01.059openalex-snapshot
Optimization of Halopemide for Phospholipase D2 inhibition
inferredcites →https://doi.org/10.1016/j.bmcl.2007.01.060openalex-snapshot
Discovery of tertiary aminoacids as dual PPARα/γ agonists-I
inferredcites →https://doi.org/10.1016/j.bmcl.2007.01.073openalex-snapshot
Inhibition of cancer cell adhesion by heterochiral Pro-containing RGD mimetics
inferredcites →https://doi.org/10.1016/j.bmcl.2007.01.077openalex-snapshot
Isoform selective inhibition of STAT1 or STAT3 homo-dimerization via peptidomimetic probes: Structural recognition of STAT SH2 domains
inferredcites →https://doi.org/10.1016/j.bmcl.2007.01.094openalex-snapshot
Quinoxalinylurea derivatives as a novel class of JSP-1 inhibitors
inferredcites →https://doi.org/10.1016/j.bmcl.2007.01.102openalex-snapshot
Discovery and initial SAR of 3-(1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-ones as inhibitors of insulin-like growth factor 1-receptor (IGF-1R)
inferredcites →https://doi.org/10.1016/j.bmcl.2007.01.117openalex-snapshot
Structural requirements of HDAC inhibitors: SAHA analogs functionalized adjacent to the hydroxamic acid
inferredcites →https://doi.org/10.1016/j.bmcl.2007.02.013openalex-snapshot
Parallel synthesis and SAR study of novel oxa-steroids as potent and selective progesterone receptor antagonists
inferredcites →https://doi.org/10.1016/j.bmcl.2007.02.054openalex-snapshot
Synthesis of enantiomerically pure milnacipran analogs and inhibition of dopamine, serotonin, and norepinephrine transporters
inferredcites →https://doi.org/10.1016/j.bmcl.2007.03.011openalex-snapshot
Optimization of imidazole amide derivatives as cannabinoid-1 receptor antagonists for the treatment of obesity
inferredcites →https://doi.org/10.1016/j.bmcl.2007.03.059openalex-snapshot
Potent bradykinin B1 receptor antagonists: 4-Substituted phenyl cyclohexanes
inferredcites →https://doi.org/10.1016/j.bmcl.2007.03.062openalex-snapshot
Synthesis and structure–activity relationships of 4-hydroxy-4-phenylpiperidines as nociceptin receptor ligands: Part 2
inferredcites →https://doi.org/10.1016/j.bmcl.2007.04.007openalex-snapshot
Synthesis and cytotoxic activity of trisubstituted-1,3,5-triazines
inferredcites →https://doi.org/10.1016/j.bmcl.2007.04.045openalex-snapshot
Hit-to-lead studies on benzimidazole inhibitors of ITK: Discovery of a novel class of kinase inhibitors
inferredcites →https://doi.org/10.1016/j.bmcl.2007.04.046openalex-snapshot
Discovery of highly potent and selective benzyloxybenzyl-based peroxisome proliferator-activator receptor (PPAR) δ agonists
inferredcites →https://doi.org/10.1016/j.bmcl.2007.04.052openalex-snapshot
Discovery of 6-ethyl-2,4-diaminopyrimidine-based small molecule renin inhibitors
inferredcites →https://doi.org/10.1016/j.bmcl.2007.04.059openalex-snapshot
Biaryl cannabinoid mimetics—Synthesis and structure–activity relationship
inferredcites →https://doi.org/10.1016/j.bmcl.2007.04.066openalex-snapshot
Novel anti-tuberculosis agents from MCR libraries
inferredcites →https://doi.org/10.1016/j.bmcl.2007.04.110openalex-snapshot
Discovery of a potent CDK2 inhibitor with a novel binding mode, using virtual screening and initial, structure-guided lead scoping
inferredcites →https://doi.org/10.1016/j.bmcl.2007.04.111openalex-snapshot
Co-crystal structure guided array synthesis of PPARγ inverse agonists
inferredcites →https://doi.org/10.1016/j.bmcl.2007.05.004openalex-snapshot
Antiproliferative and apoptosis inducing properties of pyrano[3,2-c]pyridones accessible by a one-step multicomponent synthesis
inferredcites →https://doi.org/10.1016/j.bmcl.2007.05.028openalex-snapshot
Rapid hit to lead evaluation of pyrazolo[3,4-d]pyrimidin-4-one as selective and orally bioavailable mGluR1 antagonists
inferredcites →https://doi.org/10.1016/j.bmcl.2007.05.035openalex-snapshot
Pyrazolone methylamino piperidine derivatives as novel CCR3 antagonists
inferredcites →https://doi.org/10.1016/j.bmcl.2007.05.075openalex-snapshot
Heterocyclic α-helix mimetics for targeting protein–protein interactions
inferredcites →https://doi.org/10.1016/j.bmcl.2007.05.091openalex-snapshot
Benzo[b]thiophene-based histone deacetylase inhibitors
inferredcites →https://doi.org/10.1016/j.bmcl.2007.05.103openalex-snapshot
Synthesis, in vitro and in vivo cytotoxicity of 6,7-diaryl-2,3,8,8a-tetrahydroindolizin-5(1H)-ones
inferredcites →https://doi.org/10.1016/j.bmcl.2007.05.104openalex-snapshot
In-silico fragment-based identification of novel angiogenesis inhibitors
inferredcites →https://doi.org/10.1016/j.bmcl.2007.06.019openalex-snapshot
5-((4-Aminopiperidin-1-yl)methyl)pyrrolotriazine dual inhibitors of EGFR and HER2 protein tyrosine kinases
inferredcites →https://doi.org/10.1016/j.bmcl.2007.06.022openalex-snapshot
N-(5-Chloro-2-(hydroxymethyl)-N-alkyl-arylsulfonamides as γ-secretase inhibitors
inferredcites →https://doi.org/10.1016/j.bmcl.2007.06.031openalex-snapshot
Aminopyrrolidineamide inhibitors of site-1 protease
inferredcites →https://doi.org/10.1016/j.bmcl.2007.06.051openalex-snapshot
Anthranilamide inhibitors of factor Xa
inferredcites →https://doi.org/10.1016/j.bmcl.2007.06.053openalex-snapshot
α,α-Cyclic aminoacids as useful scaffolds for the preparation of hNK2 receptor antagonists
inferredcites →https://doi.org/10.1016/j.bmcl.2007.06.070openalex-snapshot
Application of multicomponent reactions to antimalarial drug discovery. Part 3: Discovery of aminoxazole 4-aminoquinolines with potent antiplasmodial activity in vitro
inferredcites →https://doi.org/10.1016/j.bmcl.2007.06.074openalex-snapshot
Discovery and SAR studies of novel GlyT1 inhibitors
inferredcites →https://doi.org/10.1016/j.bmcl.2007.06.094openalex-snapshot
A synthetic entry to pladienolide B and FD-895
inferredcites →https://doi.org/10.1016/j.bmcl.2007.07.005openalex-snapshot
Sulfonamide derivatives as new potent and selective CB2 cannabinoid receptor agonists
inferredcites →https://doi.org/10.1016/j.bmcl.2007.07.006openalex-snapshot
Tetrapeptide inhibitors of the glutamate vesicular transporter (VGLUT)
inferredcites →https://doi.org/10.1016/j.bmcl.2007.07.082openalex-snapshot
Synthesis and biological evaluation of a C5-biphenyl thiolactomycin library
inferredcites →https://doi.org/10.1016/j.bmcl.2007.07.099openalex-snapshot
Discovery, synthesis, and structure–activity studies of tetrazole based growth hormone secretagogues
inferredcites →https://doi.org/10.1016/j.bmcl.2007.07.103openalex-snapshot
Synthesis and screening of 3-substituted thioxanthen-9-one-10,10-dioxides
inferredcites →https://doi.org/10.1016/j.bmcl.2007.08.015openalex-snapshot
Novel sulfonamides having dual dopamine D2 and D3 receptor affinity show in vivo antipsychotic efficacy with beneficial cognitive and EPS profile
inferredcites →https://doi.org/10.1016/j.bmcl.2007.08.042openalex-snapshot
Synthesis and TNF expression inhibitory properties of new thalidomide analogues derived via Heck cross coupling
inferredcites →https://doi.org/10.1016/j.bmcl.2007.08.068openalex-snapshot
Design and synthesis via click chemistry of 8,9-anhydroerythromycin A 6,9-hemiketal analogues with anti-MRSA and -VRE activity
inferredcites →https://doi.org/10.1016/j.bmcl.2007.09.010openalex-snapshot
N-Benzyl-3-sulfonamidopyrrolidines as novel inhibitors of cell division in E. coli
inferredcites →https://doi.org/10.1016/j.bmcl.2007.09.041openalex-snapshot
Antiproliferative activities of a library of hybrids between indanones and HDAC inhibitor SAHA and MS-275 analogues
inferredcites →https://doi.org/10.1016/j.bmcl.2007.09.043openalex-snapshot
New ‘chemical probes’ to examine the role of the hFPRL1 (or ALXR) receptor in inflammation
inferredcites →https://doi.org/10.1016/j.bmcl.2007.09.047openalex-snapshot
Novel scaffold for cathepsin K inhibitors
inferredcites →https://doi.org/10.1016/j.bmcl.2007.09.067openalex-snapshot
Potent achiral agonists of the ghrelin (growth hormone secretagogue) receptor. Part I: Lead identification
inferredcites →https://doi.org/10.1016/j.bmcl.2007.09.087openalex-snapshot
Synthesis and solid-phase purification of anthranilic sulfonamides as CCK-2 ligands
inferredcites →https://doi.org/10.1016/j.bmcl.2007.09.097openalex-snapshot
Solid-phase synthesis and biological evaluation of a uridinyl branched peptide urea library
inferredcites →https://doi.org/10.1016/j.bmcl.2007.10.055openalex-snapshot
Discovery of orally bioavailable and novel urea agonists of the high affinity niacin receptor GPR109A
inferredcites →https://doi.org/10.1016/j.cbpa.2006.11.031openalex-snapshot
A pipeline for ligand discovery using small-molecule microarrays
inferredcites →https://doi.org/10.1016/j.cbpa.2007.05.003openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.cclet.2006.11.030openalex-snapshot
Preparation of polymer-supported phosphine from ferrocene for palladium-catalyzed Suzuki–Miyaura cross-coupling reactions
inferredcites →https://doi.org/10.1016/j.cclet.2007.01.045openalex-snapshot
Solid-phase synthesis of (Z)-allyl iodides from 3-acetoxy-2-methylene-alkanoates with recyclable polymer-supported selenium bromide
inferredcites →https://doi.org/10.1016/j.chembiol.2007.02.004openalex-snapshot
Identification of a Small-Molecule Inhibitor of Class Ia PI3Ks with Cell-Based Screening
inferredcites →https://doi.org/10.1016/j.chembiol.2007.02.008openalex-snapshot
Natural Product-Derived Modulators of Cell Cycle Progression and Viral Entry by Enantioselective Oxa Diels-Alder Reactions on the Solid Phase
inferredcites →https://doi.org/10.1016/j.chembiol.2007.03.010openalex-snapshot
Design, Synthesis, and Evaluation of In Vivo Potency and Selectivity of Epoxysuccinyl-Based Inhibitors of Papain-Family Cysteine Proteases
inferredcites →https://doi.org/10.1016/j.chembiol.2007.04.002openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.chembiol.2007.08.012openalex-snapshot
A Class of Small Molecules that Inhibit TNFα-Induced Survival and Death Pathways via Prevention of Interactions between TNFαRI, TRADD, and RIP1
inferredcites →https://doi.org/10.1016/j.cub.2006.12.037openalex-snapshot
BI 2536, a Potent and Selective Inhibitor of Polo-like Kinase 1, Inhibits Tumor Growth In Vivo
inferredcites →https://doi.org/10.1016/j.drudis.2007.02.001openalex-snapshot
Fragment-based drug discovery of carbonic anhydrase II inhibitors by dynamic combinatorial chemistry
inferredcites →https://doi.org/10.1016/j.drudis.2007.04.007openalex-snapshot
Lead discovery by DNA-encoded chemical libraries
inferredcites →https://doi.org/10.1016/j.drudis.2007.08.005openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.drudis.2007.08.017openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.ejmech.2006.07.010openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.ejmech.2006.09.015openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.jfluchem.2006.09.012openalex-snapshot
Heptadecafluorooctanesulfonic acid (C8F17SO3H) catalyzed intramolecular hydroamination of olefinic sulfonamides in fluorous biphase system (FBS)
inferredcites →https://doi.org/10.1016/j.jfluchem.2007.01.009openalex-snapshot
Ytterbium perfluorooctanesulfonates catalyzed synthesis of benzimidazole derivatives in fluorous solvents
inferredcites →https://doi.org/10.1016/j.jfluchem.2007.03.017openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.jfluchem.2007.07.008openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.molcata.2007.03.052openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.tet.2006.12.053openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.tet.2007.01.041openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.tet.2007.01.056openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.tet.2007.02.035openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.tet.2007.02.110openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.tet.2007.03.033openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.tet.2007.03.041openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.tet.2007.03.091openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.tet.2007.03.139openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.tet.2007.04.003openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.tet.2007.04.041openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.tet.2007.05.057openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.tet.2007.06.019openalex-snapshot
PS-IIDQ: a supported coupling reagent for efficient and general amide bond formation
inferredcites →https://doi.org/10.1016/j.tet.2007.07.077openalex-snapshot
Enantioselective ethylation of aldehydes using a regenerable polymer-supported N-picolylvalinol tridentate ligand
inferredcites →https://doi.org/10.1016/j.tet.2007.08.073openalex-snapshot
Solid-phase combinatorial synthesis of benzothiazoles, benzimidazoles, and benzoxazoles using a traceless linker
inferredcites →https://doi.org/10.1016/j.tet.2007.08.119openalex-snapshot
High throughput synthesis of diverse 2,5-disubstituted indoles using titanium carbenoids bearing boronate functionality
inferredcites →https://doi.org/10.1016/j.tet.2007.09.054openalex-snapshot
Microwave-assisted traceless synthesis of hydantion-fused β-carboline scaffold
inferredcites →https://doi.org/10.1016/j.tet.2007.10.050openalex-snapshot
Lewis acid-catalyzed formation of Ugi four-component reaction product from Passerini three-component reaction system without an added amine
inferredcites →https://doi.org/10.1016/j.tet.2007.10.058openalex-snapshot
A convergent synthesis of enantiopure bicyclic scaffolds through multicomponent Ugi reaction
inferredcites →https://doi.org/10.1016/j.tet.2007.11.017openalex-snapshot
Synthesis and reactivity of 5-Br(I)-indolizines and their parallel cross-coupling reactions
inferredcites →https://doi.org/10.1016/j.tetasy.2005.12.019openalex-snapshot
New development of Meyers’ methodology: stereoselective preparation of an axially chiral 5,7-fused bicyclic lactam related to circumdatins/benzomalvins and asperlicins
inferredcites →https://doi.org/10.1016/j.tetasy.2007.06.008openalex-snapshot
Parallel synthesis of homochiral β-amino acids
inferredcites →https://doi.org/10.1016/j.tetasy.2007.11.004openalex-snapshot
Recyclable copper catalysts in the enantioselective glyoxylate-ene reaction catalyzed by chiral fluorous-tagged bis(oxazolines)
inferredcites →https://doi.org/10.1016/j.tetlet.2006.10.149openalex-snapshot
A high yielding, one-pot synthesis of O,S-dialkyl dithiocarbonates from alcohols using Mitsunobu’s reagent
inferredcites →https://doi.org/10.1016/j.tetlet.2006.11.127openalex-snapshot
Fluorous synthesis of sclerotigenin-type benzodiazepine–quinazolinones
inferredcites →https://doi.org/10.1016/j.tetlet.2006.12.050openalex-snapshot
A versatile solid-phase synthesis of 3-aryl-1,2,4-oxadiazolones and analogues
inferredcites →https://doi.org/10.1016/j.tetlet.2006.12.064openalex-snapshot
An improved and highly convergent synthesis of 4-substituted-pyrido[2,3-d]pyrimidin-7-ones
inferredcites →https://doi.org/10.1016/j.tetlet.2006.12.111openalex-snapshot
A highly regio- and chemoselective addition of carbon nucleophiles to pyrimidinones. A new route to C4 elaborated Biginelli compounds
inferredcites →https://doi.org/10.1016/j.tetlet.2007.01.005openalex-snapshot
The application of non-cross-linked polystyrene-supported triphenylarsine in Stille coupling reactions
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Applications of ortho-phenylisonitrile and ortho-N-Boc aniline for the two-step preparation of novel bis-heterocyclic chemotypes
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Stereoselective, solid phase-based synthesis of trans 3-alkyl-substituted β-lactams as analogues of cholesterol absorption inhibitors
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Solid-Phase Synthesis of Bis-Heterocyclic Compounds with Skeletal Diversity from Resin-Bound 3-Propargylamino-2-seleno-ester
inferred← citeshttps://doi.org/10.1021/cc900133kopenalex-snapshot
Parallel Synthesis of Bis-heterocyclic Isoxazolylmethyl- and Isoxazolinylmethylpyrazoles
inferred← citeshttps://doi.org/10.1021/cc900147yopenalex-snapshot
Solid-Phase Synthesis of Thiazolo[4,5-b]pyridine Derivatives Using Friedländer Reaction
inferred← citeshttps://doi.org/10.1021/cc900165jopenalex-snapshot
Efficient and Highly Selective Method for the Synthesis of Benzo(naphtho)quinoline Derivatives Catalyzed by Iodine
inferred← citeshttps://doi.org/10.1021/ci300355popenalex-snapshot
In Silico Deconstruction of ATP-Competitive Inhibitors of Glycogen Synthase Kinase-3β
inferred← citeshttps://doi.org/10.1021/co200007wopenalex-snapshot
Combinatorial and High-Throughput Screening of Materials Libraries: Review of State of the Art
inferred← citeshttps://doi.org/10.1021/co200076jopenalex-snapshot
Synthesis of Amino-Benzothiaoxazepine-1,1-dioxides Utilizing a Microwave-Assisted, SNAr Protocol
inferred← citeshttps://doi.org/10.1021/co200093copenalex-snapshot
Triazole-Containing Isothiazolidine 1,1-Dioxide Library Synthesis: One-Pot, Multi-Component Protocols for Small Molecular Probe Discovery
inferred← citeshttps://doi.org/10.1021/co200181xopenalex-snapshot
Synthesis of a Unique Isoindoline/Tetrahydroisoquinoline-based Tricyclic Sultam Library Utilizing a Heck-aza-Michael Strategy
inferred← citeshttps://doi.org/10.1021/co2001839openalex-snapshot
Facile (Triazolyl)methylation of MACOS-derived Benzofused Sultams Utilizing ROMP-derived OTP Reagents
inferred← citeshttps://doi.org/10.1021/co3000709openalex-snapshot
Diversity-Oriented Synthesis of 1-Substituted 4-Aryl-6-oxo-1,6-dihydropyridine-3-carboxamides.
inferred← citeshttps://doi.org/10.1021/co300122nopenalex-snapshot
Diversity Oriented Synthesis of a Vinblastine-Templated Library of 7-Aryl-Octahydroazonino[5,4-b]indoles via a Three-Component Reaction
inferred← citeshttps://doi.org/10.1021/co400010yopenalex-snapshot
Multicomponent Solvent-Free Synthesis Of Benzimidazolyl Imidazo[1,2-a]-pyridine Under Microwave Irradiation
inferred← citeshttps://doi.org/10.1021/co500020aopenalex-snapshot
One-Pot Isomerization–Cross Metathesis–Reduction (ICMR) Synthesis of Lipophilic Tetrapeptides
inferred← citeshttps://doi.org/10.1021/co500036nopenalex-snapshot
Ugi-Based Approaches to Quinoxaline Libraries
inferred← citeshttps://doi.org/10.1021/co500176bopenalex-snapshot
Solid-Supported Cross-Metathesis and a Formal Alkane Metathesis for the Generation of Biologically Relevant Molecules
inferred← citeshttps://doi.org/10.1021/jo901123copenalex-snapshot
Aryl−Csp3 Bond Rotation Barriers of 2-Aryl Perhydropyrrolo[3,4-c]pyrrole-1,3-diones
inferred← citeshttps://doi.org/10.1021/ol4023084openalex-snapshot
Copper-Catalyzed Electrophilic Amination of Organolithiums Mediated by Recoverable Siloxane Transfer Agents
inferred← citeshttps://doi.org/10.1021/ol500328topenalex-snapshot
Three-Component Coupling Approach for the Synthesis of Diverse Heterocycles Utilizing Reactive Nitrilium Trapping
inferred← citeshttps://doi.org/10.1039/9781849733052-00006openalex-snapshot
High Throughput Chemistry in Drug Discovery
inferred← citeshttps://doi.org/10.1039/b927161aopenalex-snapshot
Reagent based DOS: A “Click, Click, Cyclize” strategy to probe chemical space
inferred← citeshttps://doi.org/10.1039/c004729eopenalex-snapshot
Unravelling the olefin cross metathesis on solid support. Factors affecting the reaction outcome
inferred← citeshttps://doi.org/10.1039/c0ob00547aopenalex-snapshot
Polymer supported synthesis of novel benzoxazole linked benzimidazoles under microwave conditions: In vitro evaluation of VEGFR-3 kinase inhibition activity
inferred← citeshttps://doi.org/10.1039/c3ob27177copenalex-snapshot
Multistep divergent synthesis of benzimidazole linked benzoxazole/benzothiazole via copper catalyzed domino annulation
inferred← citeshttps://doi.org/10.1039/c6ra06930dopenalex-snapshot
Diversity oriented synthesis of benzimidazole-based biheterocyclic molecules by combinatorial approach: a critical review
inferred← citeshttps://doi.org/10.1039/d2qo01175aopenalex-snapshot
Rapid construction of γ-lactam containing 3,3-disubstituted oxindoles via a silver-catalyzed cascade radical bicyclization reaction
inferred← citeshttps://doi.org/10.1071/ch15029openalex-snapshot
Two Efficient One-Pot Approaches for Regioselective Synthesis of New 3-Arylpyridazino[4,3-c]quinolin-5(6H)-ones
inferred← citeshttps://doi.org/10.1073/pnas.1015254108openalex-snapshot
Diversity through phosphine catalysis identifies octahydro-1,6-naphthyridin-4-ones as activators of endothelium-driven immunity
inferred← citeshttps://doi.org/10.1080/10406638.2023.2167215openalex-snapshot
Recent Advances in the Synthesis of Quinoxalines. A Mini Review
inferred← citeshttps://doi.org/10.1134/s1068162022040021openalex-snapshot
Novel Synthesis, Reactions, and Biological Study of New Morpholino-Thieno[2,3-c][2,7]Naphthyridines as Anti-Cancer and Anti-Microbial Agents
inferred← citeshttps://doi.org/10.12794/metadc30440openalex-snapshot
Synthesis and Screening of a Combinatorial Peptide Library for Ligands to Target Transferrin: Miniaturizing the Library
inferred← citeshttps://doi.org/10.1515/hc-2011-0059openalex-snapshot
An efficient method for the synthesis of naphthoquinoline derivatives catalyzed by iodine
inferred← citeshttps://doi.org/10.1515/hc-2012-0043openalex-snapshot
Iodine-catalyzed synthesis of 5-arylanthra[2,1- c ][2,7]naphthyridine derivatives via three-component reaction
inferred← citeshttps://doi.org/10.1517/17460441.2010.488263openalex-snapshot
Current strategies for drug discovery through natural products
inferred← citeshttps://doi.org/10.1517/17460441.3.7.733openalex-snapshot
Lead generation: reality check on commonly held views
inferred← citeshttps://doi.org/10.2174/138955711796268769openalex-snapshot
Synthesis and Biological Properties of Dihydro-Oxadiazine-Based Heterocyclic Derivatives
inferred← citeshttps://doi.org/10.2478/s11696-011-0062-xopenalex-snapshot
4β-Isocyanopodophyllotoxins: valuable precursors for the synthesis of new podophyllotoxin analogues
inferred← citeshttps://doi.org/10.3389/fchem.2019.00546openalex-snapshot
Synthesis of Tris-Heterocycles via a Cascade IMCR/Aza Diels-Alder + CuAAC Strategy
inferred← citeshttps://doi.org/10.3390/molecules15020997openalex-snapshot
Synthesis of 1-(4-Trifluoromethoxyphenyl)-2,5-dimethyl-3-(2-R-thiazol-4-yl)-1H-pyrroles via Chain Heterocyclization
inferred← citeshttps://doi.org/10.3390/molecules16053802openalex-snapshot
Diversity-Oriented Synthesis Based on the DPPP-Catalyzed Mixed Double-Michael Reactions of Electron-Deficient Acetylenes and β-Amino Alcohols
inferred← citeshttps://doi.org/10.3390/molecules17055363openalex-snapshot
Parallel Synthesis of 2-Substituted 6-(5-Oxo-1-phenylpyrrolidin-3-yl)pyrimidine-5-carboxamides
inferred← citeshttps://doi.org/10.3390/molecules17055467openalex-snapshot
Solid-Phase Parallel Synthesis of Drug-Like Artificial 2H-Benzopyran Libraries
inferred← citeshttps://doi.org/10.3390/molecules25225226openalex-snapshot
Synthesis of Novel 2-(Pyridin-2-yl) Pyrimidine Derivatives and Study of Their Anti-Fibrosis Activity
inferred← citeshttps://doi.org/10.3390/molecules29225265openalex-snapshot
Recent Advances in Sequentially Pd-Catalyzed One-Pot Syntheses of Heterocycles
inferred← citeshttps://doi.org/10.3762/bjoc.13.104openalex-snapshot
New tricks of well-known aminoazoles in isocyanide-based multicomponent reactions and antibacterial activity of the compounds synthesized
inferred← citeshttps://doi.org/10.5012/bkcs.2010.31.9.2459openalex-snapshot
Liquid-Phase Synthesis of Biaryl Compounds by the Hydrogenolysis of Pentaerythritol-Supported Biarylsulfonates
inferred← citeshttps://doi.org/10.5012/bkcs.2011.32.7.2453openalex-snapshot
An Efficient Solid-Phase Synthesis of α-1,2,3-Triazoloamide Derivatives via Click Chemistry
inferred← citeshttps://doi.org/10.5155/eurjchem.4.1.1-6.718openalex-snapshot
Synthesis of 2-substituted 6-(5-oxo-1-phenylpyrrolidin-3-yl)pyrimidin-4(3H)-ones
inferred← citeshttps://doi.org/10.5935/1984-6835.20100027openalex-snapshot
The use of microwave irradiation in the fluorous synthesis
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