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Characterizing Bitterness: Identification of Key Structural Features and Development of a Classification Model

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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/jcc.540100804openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.bbrc.2004.05.019openalex-snapshot
The human taste receptor hTAS2R14 responds to a variety of different bitter compounds
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Why Americans Eat What They Do
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A Novel Family of Mammalian Taste Receptors
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T2Rs Function as Bitter Taste Receptors
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Further studies on the synthesis and tastes of monosubstituted benzenesulfamates. A semi-quantitative structure–taste relationship for the meta-compounds
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Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate
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A metabotropic glutamate receptor variant functions as a taste receptor
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The human TAS2R16 receptor mediates bitter taste in response to β-glucopyranosides
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Molecular similarity: a key technique in molecular informatics
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Umami: a universal taste
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Identification of Ligands for Two Human Bitter T2R Receptors
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Food Science and Technology Abstracts

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inferred← citeshttps://doi.org/10.2139/ssrn.4903651openalex-extracted
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inferred← citeshttps://doi.org/10.1016/j.foodres.2023.113036openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.ifset.2020.102499openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.ijpharm.2017.03.076openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.phrs.2025.107626openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.tifs.2025.105339openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/s1877-1173(10)91006-5openalex-snapshot
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inferred← citeshttps://doi.org/10.1038/s41598-019-43664-yopenalex-snapshot
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inferred← citeshttps://doi.org/10.1038/s41598-022-25935-3openalex-snapshot
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inferred← citeshttps://doi.org/10.1248/cpb.c20-00866openalex-snapshot
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inferred← citeshttps://doi.org/10.1515/psr-2018-0117openalex-snapshot
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inferred← citeshttps://doi.org/10.3389/fchem.2018.00082openalex-snapshot
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