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Molecular Scaffolds with High Propensity to Form Multi-Target Activity Cliffs
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/cmdc.200900300openalex-snapshot
From Structure–Activity to Structure–Selectivity Relationships: Quantitative Assessment, Selectivity Cliffs, and Key Compounds
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Scaffold Distributions in Bioactive Molecules, Clinical Trials Compounds, and Drugs
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Drugs in other drugs: a new look at drugs as fragments
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Chemical substructures in drug discovery
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On Outliers and Activity CliffsWhy QSAR Often Disappoints
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The Scaffold Tree − Visualization of the Scaffold Universe by Hierarchical Scaffold Classification
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Drug and Drug Candidate Building Block Analysis
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RECAPRetrosynthetic Combinatorial Analysis Procedure: A Powerful New Technique for Identifying Privileged Molecular Fragments with Useful Applications in Combinatorial Chemistry
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The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
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Methods for drug discovery: development of potent, selective, orally effective cholecystokinin antagonists
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Quest for the Rings. In Silico Exploration of Ring Universe To Identify Novel Bioactive Heteroaromatic Scaffolds
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Chemical Fragments as Foundations for Understanding Target Space and Activity Prediction
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Recent Developments in Fragment-Based Drug Discovery
inferredcites →https://doi.org/10.1021/jm800867gopenalex-snapshot
Structure−Activity Relationship Anatomy by Network-like Similarity Graphs and Local Structure−Activity Relationship Indices
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Systematic Analysis of Public Domain Compound Potency Data Identifies Selective Molecular Scaffolds across Druggable Target Families
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inferredcites →https://doi.org/10.2174/156802607782194725openalex-snapshot
Computational Techniques in Fragment Based Drug Discovery
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Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Structural and Potency Relationships between Scaffolds of Compounds Active against Human Targets
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Quantitative Structure-Epigenetic Activity Relationships
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