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Single R-Group Polymorphisms (SRPs) and R-Cliffs: An Intuitive Framework for Analyzing and Visualizing Activity Cliffs in a Single Analog Series
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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Pyrazole-based arylalkyne cathepsin S inhibitors. Part II: Optimization of cellular potency
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Pyrazole-based cathepsin S inhibitors with arylalkynes as P1 binding elements
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Proteolysis in MHC Class II Antigen Presentation
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Specificity Determinants of Human Cathepsin S Revealed by Crystal Structures of Complexes ,
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A Geodesic Framework for Analyzing Molecular Similarities
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Advanced Biological and Chemical Discovery (ABCD): Centralizing Discovery Knowledge in an Inherently Decentralized World
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Characterization of Activity Landscapes Using 2D and 3D Similarity Methods: Consensus Activity Cliffs
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Structural Interpretation of Activity Cliffs Revealed by Systematic Analysis of Structure−Activity Relationships in Analog Series
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Enhanced SAR Maps: Expanding the Data Rendering Capabilities of a Popular Medicinal Chemistry Tool
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Variable selection for QSAR by artificial ant colony systems
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Proteases involved in MHC dass II antigen presentation
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Recent Advances in the Design of Cathepsin S Inhibitors
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Structure–Activity Relationship Data Analysis: Activity Landscapes and Activity Cliffs
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Progress in the Analysis of Multiple Activity Profile of Screening Data Using Computational Approaches
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Recent Progress in Understanding Activity Cliffs and Their Utility in Medicinal Chemistry
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AnalogExplorer: A New Method for Graphical Analysis of Analog Series and Associated Structure–Activity Relationship Information
inferred← citeshttps://doi.org/10.1111/cbdd.12115openalex-snapshot
Activity Cliffs: Facts or Artifacts?
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