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Identification of the Druggable Concavity in Homology Models Using the PLB Index

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/bip.360221211openalex-snapshot
Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features
inferredcites →https://doi.org/10.1006/jmbi.1990.9999openalex-snapshot
Basic Local Alignment Search Tool
inferredcites →https://doi.org/10.1016/s0969-2126(02)00731-1openalex-snapshot
Reliability of Assessment of Protein Structure Prediction Methods
inferredcites →https://doi.org/10.1093/nar/28.1.235openalex-snapshot
The Protein Data Bank
inferredcites →https://doi.org/10.1248/cpb.55.980openalex-snapshot
A Simple Method to Improve the Odds in Finding 'Lead-Like' Compounds from Chemical Libraries

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1002/bip.22742openalex-snapshot
Identifying binding hot spots on protein surfaces by mixed‐solvent molecular dynamics: HIV‐1 protease as a test case
inferred← citeshttps://doi.org/10.1016/j.cmpb.2022.106952openalex-snapshot
Computational modeling and druggability assessment of Aggregatibacter actinomycetemcomitans leukotoxin
inferred← citeshttps://doi.org/10.1016/j.drudis.2009.04.006openalex-snapshot
Homology modeling in drug discovery: current trends and applications
inferred← citeshttps://doi.org/10.1016/j.gene.2013.03.037openalex-snapshot
Evidence of colorectal cancer risk associated variant Lys25Ser in the proximity of human bone morphogenetic protein 2
inferred← citeshttps://doi.org/10.1016/j.jbc.2021.101173openalex-snapshot
Bisphenol A derivatives act as novel coactivator-binding inhibitors for estrogen receptor β
inferred← citeshttps://doi.org/10.1021/ci100210copenalex-snapshot
Pocket Similarity: Are α Carbons Enough?
inferred← citeshttps://doi.org/10.1021/ci100312topenalex-snapshot
Drug-like Density: A Method of Quantifying the “Bindability” of a Protein Target Based on a Very Large Set of Pockets and Drug-like Ligands from the Protein Data Bank
inferred← citeshttps://doi.org/10.1021/ci800113copenalex-snapshot
Chemocavity: Specific Concavity in Protein Reserved for the Binding of Biologically Functional Small Molecules
inferred← citeshttps://doi.org/10.1038/s41598-022-08320-yopenalex-snapshot
In silico analysis of SARS-CoV-2 proteins as targets for clinically available drugs
inferred← citeshttps://doi.org/10.1038/srep33232openalex-snapshot
Improving the performance of the PLB index for ligand-binding site prediction using dihedral angles and the solvent-accessible surface area
inferred← citeshttps://doi.org/10.1093/bioinformatics/btq490openalex-snapshot
Identification of protein binding surfaces using surface triplet propensities
inferred← citeshttps://doi.org/10.1093/protein/gzq014openalex-snapshot
Use of amino acid composition to predict epitope residues of individual antibodies
inferred← citeshttps://doi.org/10.1158/1078-0432.c.6528632.v1openalex-snapshot
Data from Stratifin Inhibits SCFFBW7 Formation and Blocks Ubiquitination of Oncoproteins during the Course of Lung Adenocarcinogenesis
inferred← citeshttps://doi.org/10.1158/1078-0432.ccr-18-3631openalex-snapshot
Stratifin Inhibits SCFFBW7 Formation and Blocks Ubiquitination of Oncoproteins during the Course of Lung Adenocarcinogenesis
inferred← citeshttps://doi.org/10.1248/bpb.31.1552openalex-snapshot
Determination of Ligand-Binding Sites on Proteins Using Long-Range Hydrophobic Potential
inferred← citeshttps://doi.org/10.1380/ejssnt.2008.241openalex-snapshot
Development of Software Program Predicting the Binding Site and the Binding Mode of Ligands Against a Target Protein
inferred← citeshttps://doi.org/10.2174/138920309788452173openalex-snapshot
Quality Assessment of Protein Structure Models
inferred← citeshttps://doi.org/10.3390/ijms23094749openalex-snapshot
Inverse Mixed-Solvent Molecular Dynamics for Visualization of the Residue Interaction Profile of Molecular Probes
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