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Amphidinol, a polyhydroxy-polyene antifungal agent with an unprecedented structure, from a marine dinoflagellate, Amphidinium klebsii

https://doi.org/10.1021/ja00026a027
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Marine Microorganisms and Their Versatile Applications in Bioactive Compounds
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Synthesis of the C31–C67 Fragment of Amphidinol 3
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Die Entdeckung und Synthese von marinen Polyethern
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Synthesis and Stereochemical Revision of the C31–C67 Fragment of Amphidinol 3
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Determination of the Absolute Configuration of Super‐Carbon‐Chain Compounds by a Combined Chemical, Spectroscopic, and Computational Approach: Gibbosols A and B
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ChemInform Abstract: Amphidinol, a Polyhydroxypolyene Antifungal Agent with an Unprecedented Structure, from a Marine Dinoflagellate, Amphidinium klebsii.
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Cooliatoxin, the first toxin from Coolia monotis (dinophyceae)
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Negative‐ion fast‐atom bombardment tandem mass spectrometry for the structural study of polyether compounds: Structural verification of yessotoxin
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Structural confirmation of ostreocin‐D by application of negative‐ion fast‐atom bombardment collision‐induced dissociation tandem mass spectrometric methods
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Bioactive Structure of Membrane Lipids and Natural Products Elucidated by a Chemistry‐Based Approach
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Separation and Isolation Techniques
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Bioactive Marine Toxins
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Marine Polyether Compounds
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Benthic dinoflagellate blooms in tropical intertidal rock pools: elucidation of photoprotection mechanisms
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Bioactivity of Amphidinol-Containing Extracts of Amphidinium carterae Grown Under Varying Cultivation Conditions
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Conformational analysis of natural products using long-range carbon-proton coupling constants: Three-dimensional structure of okadaic acid in solution
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Microginin, an angiotensin-converting enzyme inhibitor from the blue-green alga Microcystis aeruginosa
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Amphidinin A, a novel amphidinolide-related metabolite from the cultured marine dinoflagellate Amphidinium sp.
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Isolation and chemical structure of amphidinol 2, a potent hemolytic compound from marine dinoflagellate Amphidinium klebsii
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Marine Natural Products and Marine Chemical Ecology
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Marine dinoflagellates as a source of new bioactive structures
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Biotechnological exploitation of cyanobacteria and microalgae for bioactive compounds
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Bioactive Metabolites from Marine Dinoflagellates
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Recent Solid-State NMR Studies of Hydrated Lipid Membranes
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Structural Diversity of Microalgal Marine Toxins
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A pilot-scale bioprocess to produce amphidinols from the marine microalga Amphidinium carterae: Isolation of a novel analogue
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Effects of hormones on the growth and metabolite production of Amphidinium carterae under carbon sufficient and carbon limited conditions
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The cytotoxic mechanism of karlotoxin 2 (KmTx 2) from Karlodinium veneficum (Dinophyceae)
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Membrane-permeabilizing activities of amphidinol 3, polyene-polyhydroxy antifungal from a marine dinoflagellate
inferred← citeshttps://doi.org/10.1016/j.bbamem.2008.01.018openalex-snapshot
Roles of integral protein in membrane permeabilization by amphidinols
inferred← citeshttps://doi.org/10.1016/j.bbrep.2021.100941openalex-snapshot
Amphidinol 3 preferentially binds to cholesterol in disordered domains and disrupts membrane phase separation
inferred← citeshttps://doi.org/10.1016/j.biopha.2023.115532openalex-snapshot
Antitumor effect of algae silver nanoparticles on human triple negative breast cancer cells
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Life-cycle assessment of a microalgae-based fungicide under a biorefinery approach
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Bioprospecting for bioactive compounds in microalgae: Antimicrobial compounds
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Structures of new amphidinols with truncated polyhydroxyl chain and their membrane-permeabilizing activities
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Effects of lipid constituents on membrane-permeabilizing activity of amphidinols
inferred← citeshttps://doi.org/10.1016/j.bmcl.2004.04.029openalex-snapshot
Lingshuiol, a novel polyhydroxyl compound with strongly cytotoxic activity from the marine dinoflagellate Amphidinium sp
inferred← citeshttps://doi.org/10.1016/j.bmcl.2010.02.025openalex-snapshot
Sterol effect on interaction between amphidinol 3 and liposomal membrane as evidenced by surface plasmon resonance
inferred← citeshttps://doi.org/10.1016/j.bmcl.2014.12.003openalex-snapshot
Amphirionin-2, a novel linear polyketide with potent cytotoxic activity from a marine dinoflagellate Amphidinium species
inferred← citeshttps://doi.org/10.1016/j.bmcl.2023.129594openalex-snapshot
Truncated Derivatives of Amphidinol 3 Reveal the Functional Role of Polyol Chain in Sterol-Recognition and Pore Formation
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The structures of five new antifungal and hemolytic amphidinol analogs from Amphidinium carterae collected in New Zealand
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Karlodinium veneficum—The little dinoflagellate with a big bite
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A fish kill associated with a bloom of Amphidinium carterae in a coastal lagoon in Sydney, Australia
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An evaluation of the genus Amphidinium (Dinophyceae) combining evidence from morphology, phylogenetics, and toxin production, with the introduction of six novel species
inferred← citeshttps://doi.org/10.1016/j.hal.2020.101905openalex-snapshot
Karmitoxin production by Karlodinium armiger and the effects of K. armiger and karmitoxin towards fish
inferred← citeshttps://doi.org/10.1016/j.hal.2024.102797openalex-snapshot
The cytotoxicity of the haptophyte Chrysochromulina leadbeateri towards the Atlantic salmon gill cell line ASG-10
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The cytotoxic and hemolytic potential of karmitoxin from Karlodinium armiger and how it interacts with sterols
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Utilization of two types of dissolved organic phosphate by axenic and nonaxenic harmful Amphidinium carterae: Response of photosynthetic and hemolytic activity
inferred← citeshttps://doi.org/10.1016/j.hal.2025.102934openalex-snapshot
Phylogenetic analysis of the toxigenic genus Amphidinium (Amphidiniales, Dinophyceae) revealed an unexpectedly high diversity in the Asia–Pacific region
inferred← citeshttps://doi.org/10.1016/j.lwt.2025.118633openalex-snapshot
Algal amphidinols, an alternative to sulfites in the fight against Brettanomyces bruxellensis
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In vitro evaluation of the potential allelopathic and ichthyotoxic effect of the raphidophyte Heterosigma akashiwo and the dinoflagellate Alexandrium catenella
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Hemolysis associated toxicities of benthic dinoflagellates from Hong Kong waters
inferred← citeshttps://doi.org/10.1016/j.phytol.2022.08.001openalex-snapshot
Amphidinol C, a major polyketide from an Irish strain of the dinoflagellate Amphidinium carterae
inferred← citeshttps://doi.org/10.1016/j.tet.2005.01.069openalex-snapshot
Hairpin conformation of amphidinols possibly accounting for potent membrane permeabilizing activities
inferred← citeshttps://doi.org/10.1016/j.tet.2005.07.004openalex-snapshot
Isolation and structure elucidation of a new amphidinol with a truncated polyhydroxyl chain from Amphidinium klebsii
inferred← citeshttps://doi.org/10.1016/j.tet.2011.12.070openalex-snapshot
Integrated approaches to the configurational assignment of marine natural products
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Total syntheses of both enantiomers of amphirionin 4: A chemoenzymatic based strategy for functionalized tetrahydrofurans
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Lingshuiols A and B, two new polyhydroxy compounds from the Chinese marine dinoflagellate Amphidinium sp.
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Synthesis of highly substituted 2,6-anti-configured tetrahydropyrans. First steps towards an efficient access to amphidinol 3 ring system
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Karatungiols A and B, two novel antimicrobial polyol compounds, from the symbiotic marine dinoflagellate Amphidinium sp.
inferred← citeshttps://doi.org/10.1016/j.tetlet.2006.04.094openalex-snapshot
Amphezonol A, a novel polyhydroxyl metabolite from marine dinoflagellate Amphidinium sp.
inferred← citeshttps://doi.org/10.1016/j.tetlet.2008.08.035openalex-snapshot
Synthetic studies directed toward amphidinol 2: elucidation of the relative configuration of the C1–C10 fragment
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Isolation and characterization of karlotoxin 1, a new amphipathic toxin from Karlodinium veneficum
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Carteraol E, a potent polyhydroxyl ichthyotoxin from the dinoflagellate Amphidinium carterae
inferred← citeshttps://doi.org/10.1016/j.tetlet.2011.11.033openalex-snapshot
Amdigenol A, a long carbon-backbone polyol compound, produced by the marine dinoflagellate Amphidinium sp
inferred← citeshttps://doi.org/10.1016/j.tetlet.2014.04.086openalex-snapshot
Amphirionin-5, a novel linear polyketide from a cultured marine dinoflagellate Amphidinium species with a potent cell proliferation-promoting activity
inferred← citeshttps://doi.org/10.1016/j.tetlet.2014.09.094openalex-snapshot
Amdigenols E and G, long carbon-chain polyol compounds, isolated from the marine dinoflagellate Amphidinium sp.
inferred← citeshttps://doi.org/10.1016/j.tetlet.2020.152376openalex-snapshot
Amdigenol D, a long carbon-chain polyol, isolated from the marine dinoflagellate Amphidinium sp.
inferred← citeshttps://doi.org/10.1016/j.tetlet.2025.155586openalex-snapshot
Syntheses of C22–C29 and C20–C29 sections of amphidinol 3
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Biosynthesis of toxic naturally-occurring seafood contaminants
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Toxicity assessment of Amphidinium carterae, Coolia cfr. monotis and Ostreopsis cfr. ovata (Dinophyta) isolated from the northern Ionian Sea (Mediterranean Sea)
inferred← citeshttps://doi.org/10.1016/j.toxicon.2014.08.003openalex-snapshot
Acute toxicity of karlotoxins to mice
inferred← citeshttps://doi.org/10.1016/s0040-4020(01)00481-1openalex-snapshot
Acetate labeling patterns of dinoflagellate polyketides, amphidinols 2, 3 and 4
inferred← citeshttps://doi.org/10.1016/s0040-4020(98)00898-9openalex-snapshot
Luteophanols B and C, new polyhydroxyl compounds from marine dinoflagellate Amphidinium sp.
inferred← citeshttps://doi.org/10.1016/s0040-4039(00)02331-5openalex-snapshot
Spiro-prorocentrimine, a novel macrocyclic lactone from a benthic Prorocentrum sp. of Taiwan
inferred← citeshttps://doi.org/10.1016/s0040-4039(01)00478-6openalex-snapshot
Structural determination of pteriatoxins A, B and C, extremely potent toxins from the bivalve Pteria penguin
inferred← citeshttps://doi.org/10.1016/s0040-4039(01)00480-4openalex-snapshot
Pinnatoxins B and C, the most toxic components in the pinnatoxin series from the Okinawan bivalve Pinna muricata
inferred← citeshttps://doi.org/10.1016/s0040-4039(99)02170-xopenalex-snapshot
Amphidinolide V, novel 14-membered macrolide from marine dinoflagellate Amphidinium sp.
inferred← citeshttps://doi.org/10.1016/s0041-0101(00)00255-5openalex-snapshot
Toxic marine microalgae
inferred← citeshttps://doi.org/10.1016/s0041-0101(98)00133-0openalex-snapshot
Identification of putative palytoxin as the cause of clupeotoxism
inferred← citeshttps://doi.org/10.1016/s0305-0491(99)00107-8openalex-snapshot
Polyketides from dinoflagellates: origins, pharmacology and biosynthesis
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Stereoselective α-amidoalkylation reactions of phenylglycinol-derived bicyclic lactams
inferred← citeshttps://doi.org/10.1017/s0967026202003591openalex-snapshot
The benthic dinoflagellate genus Amphidinium in south-eastern Australian waters, including three new species
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The Chemistry of Phytoplankton
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Chemical Diversity, Origin, and Analysis of Phycotoxins
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Karmitoxin: An Amine-Containing Polyhydroxy-Polyene Toxin from the Marine Dinoflagellate Karlodinium armiger
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.7b00345openalex-snapshot
Structures of the Largest Amphidinol Homologues from the Dinoflagellate Amphidinium carterae and Structure–Activity Relationships
inferred← citeshttps://doi.org/10.1021/acs.joc.7b02569openalex-snapshot
Determination of the Absolute Configuration of Polyhydroxy Compound Ostreol B Isolated from the Dinoflagellate Ostreopsis cf. ovata
inferred← citeshttps://doi.org/10.1021/acs.joc.8b02033openalex-snapshot
Unified Strategy for 1,5,9- and 1,5,7-Triols via Configuration-Encoded 1,5-Polyol Synthesis: Enantioselective Preparation of γ-Sulfonyl-α-silyloxyaldehydes and Iterative Julia–Kocienski Coupling
inferred← citeshttps://doi.org/10.1021/acs.orglett.0c04075openalex-snapshot
A Water-Soluble 5/14-Carbobicyclic Steroid with a trans-9,11-Epoxy Ring from the Marine Dinoflagellate Amphidinium gibbosum: Insights into Late-Stage Diversification of Steroids
inferred← citeshttps://doi.org/10.1021/bi5002932openalex-snapshot
Direct and Stereospecific Interaction of Amphidinol 3 with Sterol in Lipid Bilayers
inferred← citeshttps://doi.org/10.1021/cr0406209openalex-snapshot
Synthetic Chemistry of Halichlorine and the Pinnaic Acids
inferred← citeshttps://doi.org/10.1021/cr800296popenalex-snapshot
Natural Product Synthesis Using Multicomponent Reaction Strategies
inferred← citeshttps://doi.org/10.1021/ja971547popenalex-snapshot
Labeling Pattern of Okadaic Acid from 18O2 and [18O2]Acetate Elucidated by Collision-Induced Dissociation Tandem Mass Spectrometry
inferred← citeshttps://doi.org/10.1021/ja981413ropenalex-snapshot
Azaspiracid, a New Marine Toxin Having Unique Spiro Ring Assemblies, Isolated from Irish Mussels, Mytilus edulis
inferred← citeshttps://doi.org/10.1021/ja983655xopenalex-snapshot
Absolute Configuration of Amphidinol 3, the First Complete Structure Determination from Amphidinol Homologues: Application of a New Configuration Analysis Based on Carbon−Hydrogen Spin-Coupling Constants
inferred← citeshttps://doi.org/10.1021/jacs.9b11789openalex-snapshot
Total Synthesis of Amphidinol 3: A General Strategy for Synthesizing Amphidinol Analogues and Structure–Activity Relationship Study
inferred← citeshttps://doi.org/10.1021/jo016089oopenalex-snapshot
Amphidinolide W, a New 12-Membered Macrolide from Dinoflagellate Amphidinium sp.
inferred← citeshttps://doi.org/10.1021/jo025899copenalex-snapshot
Connective Synthesis of Polysubstituted Tetrahydropyrans by a Novel and Stereocontrolled Metallo-ene/Intramolecular Sakurai Cyclization Sequence
inferred← citeshttps://doi.org/10.1021/jo0266083openalex-snapshot
Enantioselective Synthesis of Piperidine, Indolizidine, and Quinolizidine Alkaloids from a Phenylglycinol-Derived δ-Lactam
inferred← citeshttps://doi.org/10.1021/jo052383vopenalex-snapshot
Selectivity Guidelines and a Reductive Elimination-Based Model for Predicting the Stereochemical Course of Conjugate Addition Reactions of Organocuprates to γ-Alkoxy-α,β-enoates
inferred← citeshttps://doi.org/10.1021/jo102585kopenalex-snapshot
Prorocentrol, a Polyoxy Linear Carbon Chain Compound Isolated from the Toxic Dinoflagellate Prorocentrum hoffmannianum
inferred← citeshttps://doi.org/10.1021/jo502322mopenalex-snapshot
Stereoselective Synthesis of the C1–C29 Part of Amphidinol 3
inferred← citeshttps://doi.org/10.1021/jo901793fopenalex-snapshot
Stereoselective Synthesis of the C31−C40/C43−C52 Unit of Amphidinol 3
inferred← citeshttps://doi.org/10.1021/jo960185lopenalex-snapshot
Asymmetric Synthesis of Cis-Fused Bicyclic Pyrrolidines and Pyrrolidinones via Chiral Polycyclic Lactams
inferred← citeshttps://doi.org/10.1021/jo970273lopenalex-snapshot
Luteophanol A, a New Polyhydroxyl Compound from Symbiotic Marine Dinoflagellate Amphidinium sp.
inferred← citeshttps://doi.org/10.1021/jo981810kopenalex-snapshot
Stereochemical Determination of Acyclic Structures Based on Carbon−Proton Spin-Coupling Constants. A Method of Configuration Analysis for Natural Products
inferred← citeshttps://doi.org/10.1021/jo981882bopenalex-snapshot
Colopsinol A, a Novel Polyhydroxyl Metabolite from Marine Dinoflagellate Amphidinium sp.
inferred← citeshttps://doi.org/10.1021/jo982004gopenalex-snapshot
Remote Asymmetric Induction in Michael Additions of Allylic Sulfones
inferred← citeshttps://doi.org/10.1021/jo991393ropenalex-snapshot
Amphidinolide T, Novel 19-Membered Macrolide from Marine Dinoflagellate Amphidinium sp.
inferred← citeshttps://doi.org/10.1021/np0605844openalex-snapshot
Bioactive Macrolides and Polyketides from Marine Dinoflagellates of the Genus Amphidinium
inferred← citeshttps://doi.org/10.1021/np060596popenalex-snapshot
Zooxanthellamide D, a Polyhydroxy Polyene Amide from a Marine Dinoflagellate, and Chemotaxonomic Perspective of the Symbiodinium Polyols
inferred← citeshttps://doi.org/10.1021/np100158ropenalex-snapshot
Structure and Relative Potency of Several Karlotoxins from Karlodinium veneficum
inferred← citeshttps://doi.org/10.1021/np100221kopenalex-snapshot
Symbiopolyol, a VCAM-1 Inhibitor from a Symbiotic Dinoflagellate of the Jellyfish Mastigias papua
inferred← citeshttps://doi.org/10.1021/np300604wopenalex-snapshot
Confirmation of the Absolute Configuration at C45 of Amphidinol 3
inferred← citeshttps://doi.org/10.1021/np500275xopenalex-snapshot
Antifungal Amphidinol 18 and Its 7-Sulfate Derivative from the Marine Dinoflagellate Amphidinium carterae
inferred← citeshttps://doi.org/10.1021/np900616qopenalex-snapshot
Structure and Biosynthesis of Amphidinol 17, a Hemolytic Compound from Amphidinium carterae
inferred← citeshttps://doi.org/10.1021/ol0157095openalex-snapshot
Chemoselective Cross-Metathesis Reaction. Application to the Synthesis of the C1−C14 Fragment of Amphidinol 3
inferred← citeshttps://doi.org/10.1021/ol025759popenalex-snapshot
Caylobolide A, a Unique 36-Membered Macrolactone from a Bahamian Lyngbya majuscula
inferred← citeshttps://doi.org/10.1021/ol050250qopenalex-snapshot
Synthesis of the C(1)−C(25) Fragment of Amphidinol 3: Application of the Double-Allylboration Reaction for Synthesis of 1,5-Diols
inferred← citeshttps://doi.org/10.1021/ol050477lopenalex-snapshot
A C-Glycosidation Approach to the Central Core of Amphidinol 3: Synthesis of the C39−C52 Fragment
inferred← citeshttps://doi.org/10.1021/ol0511833openalex-snapshot
The Polyol Domain of Amphidinol 3. A Stereoselective Synthesis of the Entire C(1)−C(30) Sector
inferred← citeshttps://doi.org/10.1021/ol052322jopenalex-snapshot
Synthesis of the C(43)−C(67) Fragment of Amphidinol 3
inferred← citeshttps://doi.org/10.1021/ol062875+openalex-snapshot
Development of an Access Route to the C31−C52 Central Core of Amphidinol 3
inferred← citeshttps://doi.org/10.1021/ol1015898openalex-snapshot
Synthesis of the Bis-tetrahydropyran Core of Amphidinol 3
inferred← citeshttps://doi.org/10.1021/ol1021417openalex-snapshot
Versatile Configuration-Encoded Strategy for Rapid Synthesis of 1,5-Polyol Stereoisomers
inferred← citeshttps://doi.org/10.1021/ol401176aopenalex-snapshot
Synthesis and Structure Revision of the C43–C67 Part of Amphidinol 3
inferred← citeshttps://doi.org/10.1021/ol5023504openalex-snapshot
Amphirionin-4 with Potent Proliferation-Promoting Activity on Bone Marrow Stromal Cells from a Marine Dinoflagellate Amphidinium Species
inferred← citeshttps://doi.org/10.1021/ol7020934openalex-snapshot
Synthesis of the C1−C52 Fragment of Amphidinol 3, Featuring a β-Alkoxy Alkyllithium Addition Reaction
inferred← citeshttps://doi.org/10.1021/ol703042qopenalex-snapshot
Synthesis of the C(26)−C(42) and C(43)−C(67) Pyran-Containing Fragments of Amphidinol 3 via a Common Pyran Intermediate
inferred← citeshttps://doi.org/10.1021/ol8016337openalex-snapshot
Structure of Membrane-Bound Amphidinol 3 in Isotropic Small Bicelles
inferred← citeshttps://doi.org/10.1021/ol802168ropenalex-snapshot
Combinatorial Synthesis of the 1,5-Polyol System Based on Cross Metathesis: Structure Revision of Amphidinol 3
inferred← citeshttps://doi.org/10.1038/aps.2012.110openalex-snapshot
Bioactive natural products from Chinese marine flora and fauna
inferred← citeshttps://doi.org/10.1038/ja.2006.72openalex-snapshot
Amphidinin B, a New Polyketide Metabolite from Marine Dinoflagellate Amphidinium sp.
inferred← citeshttps://doi.org/10.1038/ja.2007.51openalex-snapshot
Amphidinolactone B, a New 26-Membered Macrolide from Dinoflagellate Amphidinium sp.
inferred← citeshttps://doi.org/10.1038/s41429-021-00468-5openalex-snapshot
Marine natural products targeting the eukaryotic cell membrane
inferred← citeshttps://doi.org/10.1038/s41598-024-68669-0openalex-snapshot
Sterolysin from a 1950s culture of Karlodinium veneficum (aka Gymnodinium veneficum Ballantine) forms lethal sterol dependent membrane pores
inferred← citeshttps://doi.org/10.1039/b310427nopenalex-snapshot
Amphidinolides, bioactive macrolides from symbiotic marine dinoflagellatesThe authors dedicate this review to the late Professor D. John Faulkner.
inferred← citeshttps://doi.org/10.1039/b700307mopenalex-snapshot
Synthesis of macrocyclic shellfish toxins containing spiroimine moieties
inferred← citeshttps://doi.org/10.1039/b809658aopenalex-snapshot
Structural revisions of natural products by total synthesis
inferred← citeshttps://doi.org/10.1039/c0np00002gopenalex-snapshot
3D structures of membrane-associated small molecules as determined in isotropic bicelles
inferred← citeshttps://doi.org/10.1039/c2ob26641eopenalex-snapshot
Diastereoselective synthesis of the C17–C30 fragment of amphidinol 3
inferred← citeshttps://doi.org/10.1039/c39940001455openalex-snapshot
Amphidinolide N, a novel 26-membered macrolide with remarkably potent cytotoxicity from the cultured marine dinoflagellate Amphidinium sp.
inferred← citeshttps://doi.org/10.1039/c3np70062copenalex-snapshot
Isolation, structural determination and synthetic approaches toward amphidinol 3
inferred← citeshttps://doi.org/10.1039/c3ob41569dopenalex-snapshot
Diastereoselective synthesis of the C14–C29 fragment of amphidinol 3
inferred← citeshttps://doi.org/10.1039/c5sc00814jopenalex-snapshot
A highly convergent synthesis of the C1–C31 polyol domain of amphidinol 3 featuring a TST-RCM reaction: confirmation of the revised relative stereochemistry
inferred← citeshttps://doi.org/10.1039/c9np00009gopenalex-snapshot
Approaches for the isolation and identification of hydrophilic, light-sensitive, volatile and minor natural products
inferred← citeshttps://doi.org/10.1039/c9np00059copenalex-snapshot
Chemical diversity and mode of action of natural products targeting lipids in the eukaryotic cell membrane
inferred← citeshttps://doi.org/10.1039/c9np00070dopenalex-snapshot
Inspirations from tetrafibricin and related polyketides: new methods and strategies for 1,5-polyol synthesis
inferred← citeshttps://doi.org/10.1039/d1sc02810copenalex-snapshot
Discovery of benthol A and its challenging stereochemical assignment: opening up a new window for skeletal diversity of super-carbon-chain compounds
inferred← citeshttps://doi.org/10.1039/d2np00023gopenalex-snapshot
Pitfalls in the structural elucidation of small molecules. A critical analysis of a decade of structural misassignments of marine natural products
inferred← citeshttps://doi.org/10.1046/j.1529-8817.2004.03132.xopenalex-snapshot
AMPHIDINIUM REVISITED. II. RESOLVING SPECIES BOUNDARIES IN THE AMPHIDINIUM OPERCULATUM SPECIES COMPLEX (DINOPHYCEAE), INCLUDING THE DESCRIPTIONS OF AMPHIDINIUM TRULLA SP. NOV. AND AMPHIDINIUM GIBBOSUM. COMB. NOV.1
inferred← citeshttps://doi.org/10.1073/pnas.0400368101openalex-snapshot
The structure of zetekitoxin AB, a saxitoxin analog from the Panamanian golden frog Atelopus zeteki : A potent sodium-channel blocker
inferred← citeshttps://doi.org/10.1080/00318884.2022.2033948openalex-snapshot
Phylogeny of Amphidinium (Dinophyceae) from Guam and Okinawa, with descriptions of A. pagoense sp. nov. and A. uduigamense sp. nov.
inferred← citeshttps://doi.org/10.1146/annurev.micro.50.1.431openalex-snapshot
MICROALGAL METABOLITES: A New Perspective
inferred← citeshttps://doi.org/10.1246/bcsj.20200151openalex-snapshot
Structure Determination, Chemical Synthesis, and Evaluation of Biological Activity of Super Carbon Chain Natural Products
inferred← citeshttps://doi.org/10.1246/bcsj.20220273openalex-snapshot
Formation of a Tight Complex between Amphidinol 3 and Sterols in Lipid Bilayers Revealed by Short-Range Energy Transfer
inferred← citeshttps://doi.org/10.1246/bcsj.20230166openalex-snapshot
NMR Studies on the Structure and Functions of Small Biomolecules with Highly Flexible Conformation
inferred← citeshttps://doi.org/10.1246/bcsj.81.307openalex-snapshot
Structural Features of Dinoflagellate Toxins Underlying Biological Activity as Viewed by NMR
inferred← citeshttps://doi.org/10.1246/cl.170050openalex-snapshot
Synthesis of a Truncated Analog of Amphidinol 3 Corresponding to the C21–C39/C52–C67 Section
inferred← citeshttps://doi.org/10.1246/cl.1998.653openalex-snapshot
Structures of New Pectenotoxin Analogs, Pectenotoxin-2 Seco Acid and 7-epi-Pectenotoxin-2 Seco Acid, Isolated from a Dinoflagellate and Greenshell Mussels
inferred← citeshttps://doi.org/10.1246/cl.2005.454openalex-snapshot
Iminium Alkaloids from Marine Invertebrates: Structure, Biological Activity, and Biogenesis
inferred← citeshttps://doi.org/10.1351/pac-con-11-09-32openalex-snapshot
Recent insights into natural venoms
inferred← citeshttps://doi.org/10.1371/journal.pone.0038253openalex-snapshot
Genetic Diversity, Morphological Uniformity and Polyketide Production in Dinoflagellates (Amphidinium, Dinoflagellata)
inferred← citeshttps://doi.org/10.1515/znc-2016-0043openalex-snapshot
Membrane permeabilizing action of amphidinol 3 and theonellamide A in raft-forming lipid mixtures
inferred← citeshttps://doi.org/10.2116/analsci.19.1593openalex-snapshot
Analyses of Anandamide and Endocannabinoid-like Compounds Using Collision-induced Dissociation in Fast Atom Bombardment Ionization-Mass Spectrometry and Gas Chromatography/Chemical Ionization-Mass Spectrometry
inferred← citeshttps://doi.org/10.2116/analsci.22.921openalex-snapshot
Studies on High-energy Collision-induced Dissociation of Endogenous Cannabinoids: 2-Arachidonoylglycerol and N-Arachidonoylethanolamide in FAB–Mass Spectrometry
inferred← citeshttps://doi.org/10.21203/rs.3.rs-3048270/v1openalex-snapshot
Bioactivity of amphidinol-like extracts of Amphidinium carterae grown under varying cultivation conditions
inferred← citeshttps://doi.org/10.2183/pjab.101.016openalex-snapshot
Conformational dynamics and molecular interactions of natural products: unveiling functional structures in biological membranes
inferred← citeshttps://doi.org/10.3109/15569549609064079openalex-snapshot
Chemistry, Etiology and Determination Methods of Ciguatera Toxins
inferred← citeshttps://doi.org/10.3389/fmars.2019.00148openalex-snapshot
A Review on the Biodiversity and Biogeography of Toxigenic Benthic Marine Dinoflagellates of the Coasts of Latin America
inferred← citeshttps://doi.org/10.3390/ijms22094383openalex-snapshot
Unlocking the Health Potential of Microalgae as Sustainable Sources of Bioactive Compounds
inferred← citeshttps://doi.org/10.3390/ijms222212196openalex-snapshot
Antibacterial Activity and Amphidinol Profiling of the Marine Dinoflagellate Amphidinium carterae (Subclade III)
inferred← citeshttps://doi.org/10.3390/md12105258openalex-snapshot
SxtA and sxtG Gene Expression and Toxin Production in the Mediterranean Alexandrium minutum (Dinophyceae)
inferred← citeshttps://doi.org/10.3390/md14090159openalex-snapshot
Antimicrobial Compounds from Eukaryotic Microalgae against Human Pathogens and Diseases in Aquaculture
inferred← citeshttps://doi.org/10.3390/md15060157openalex-snapshot
The Missing Piece in Biosynthesis of Amphidinols: First Evidence of Glycolate as a Starter Unit in New Polyketides from Amphidinium carterae
inferred← citeshttps://doi.org/10.3390/md15090278openalex-snapshot
HPLC-HRMS Quantification of the Ichthyotoxin Karmitoxin from Karlodinium armiger
inferred← citeshttps://doi.org/10.3390/md15120393openalex-snapshot
Biotechnological and Pharmacological Applications of Biotoxins and Other Bioactive Molecules from Dinoflagellates
inferred← citeshttps://doi.org/10.3390/md17070385openalex-snapshot
Amphidinol 22, a New Cytotoxic and Antifungal Amphidinol from the Dinoflagellate Amphidinium carterae
inferred← citeshttps://doi.org/10.3390/md18100497openalex-snapshot
LC-MS/MS Method Development for the Discovery and Identification of Amphidinols Produced by Amphidinium
inferred← citeshttps://doi.org/10.3390/md18120590openalex-snapshot
A Polyol-Polyol Super-Carbon-Chain Compound Containing Thirty-Six Carbon Stereocenters from the Dinoflagellate Amphidinium gibbosum: Absolute Configuration and Multi-Segment Modification
inferred← citeshttps://doi.org/10.3390/md20040271openalex-snapshot
Phytoplankton Toxins and Their Potential Therapeutic Applications: A Journey toward the Quest for Potent Pharmaceuticals
inferred← citeshttps://doi.org/10.3390/md20050292openalex-snapshot
Natural Polyether Ionophores and Their Pharmacological Profile
inferred← citeshttps://doi.org/10.3390/md20050333openalex-snapshot
Approaches to Configuration Determinations of Flexible Marine Natural Products: Advances and Prospects
inferred← citeshttps://doi.org/10.3390/md201039openalex-snapshot
Bioactive Alkaloids from the Sea: A Review
inferred← citeshttps://doi.org/10.3390/md23060255openalex-snapshot
Bioactive Polyketides from Amphidinium spp.: An In-Depth Review of Biosynthesis, Applications, and Current Research Trends
inferred← citeshttps://doi.org/10.3390/md23090332openalex-snapshot
High Inter- and Intraspecific Variability in Amphidinol Content and Toxicity of Amphidinium Strains
inferred← citeshttps://doi.org/10.3390/md304113openalex-snapshot
Luteophanol D, New Polyhydroxyl Metabolite from Marine Dinoflagellate Amphidinium sp.
inferred← citeshttps://doi.org/10.3390/md7040497openalex-snapshot
Preliminary Characterization of Extracellular Allelochemicals of the Toxic Marine Dinoflagellate Alexandrium tamarense Using a Rhodomonas salina Bioassay
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