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Jaspamide, a modified peptide from a Jaspis sponge, with insecticidal and antifungal activity

https://doi.org/10.1021/ja00271a062
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Intricate aspects of sponge chemistry
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Jasplakinolide, a novel actin targeting peptide, inhibits cell growth and induces actin filament polymerization in the green alga Micrasterias
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Microfilament stabilization by jasplakinolide arrests oocyte maturation, cortical granule exocytosis, sperm incorporation cone resorption, and cell-cycle progression, but not DNA replication, during fertilization in mice
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Peptide Mimetic Design with the Aid of Computational Chemistry
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Matrix Isolation Studies of Silicon Compounds
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Cyclic Peptides and Betalains
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Porifera (Sponges)–1
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Cyclic Peptides
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Marine Peptide Secondary Metabolites
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The Potential of Peptides and Depsipeptides from Terrestrial and Marine Organisms in the Fight against Human Protozoan Diseases
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Welche Struktur hat der Calmodulin‐Antagonist Konbamid aus Theonella sp.? – Synthese zweier Isomere durch direkte biomimetische Einführung von Brom in hydroxytryptophanhaltige Cyclopeptide
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Der Einfluss bakterieller Genomik auf die Naturstoff‐Forschung
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Chondramid C: Synthese, Strukturaufklärung und Struktur‐Aktivitäts‐Beziehungen
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Flexible Molecules with Defined Shape—Conformational Design
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Marine Metabolites and Metal Ion Chelation: The Facts and the Fantasies
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What is the Structure of the Calmodulin Antagonist Konbamide from Theonella sp.? Synthesis of Two Isomers by Direct Biomimetic Introduction of Bromine in Hydroxytryptophan‐Containing Cyclic Peptides
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The Impact of Bacterial Genomics on Natural Product Research
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Chondramide C: Synthesis, Configurational Assignment, and Structure–Activity Relationship Studies
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Bioactive Natural Products from Papua New Guinea Marine Sponges
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Utilizing the Power of Microbial Genetics to Bridge the Gap Between the Promise and the Application of Marine Natural Products
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Discovery of Additional Members of the Tyrosine Aminomutase Enzyme Family and the Mutational Analysis of CmdF
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Total Synthesis of (−)‐Doliculide, Structure–Activity Relationship Studies and Its Binding to F‐Actin
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Discovery and Biological Activity of New Chondramides from Chondromyces sp.
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Synthesis of Jasplakinolide Analogues Containing a Novel ω‐Amino Acid
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Total Synthesis and Configurational Assignment of Chondramide A
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Synthesis of Chondramide A Analogues with Modified β‐Tyrosine and Their Biological Evaluation
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A Straightforward Synthesis of Polyketides via Ester Dienolate Matteson Homologation
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ChemInform Abstract: Jaspamide (I), a Modified Peptide from a Jaspis Sponge, with Insecticidal and Antifungal Activity.
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ChemInform Abstract: Marine Natural Products as Leads to Develop New Drugs and Insecticides
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Stellarins F and G, two new cyclopeptides from Stellaria yunnanensis
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Actin polymerization promotes the reversal of streaming in the apex of pollen tubes
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Synthesis and Conformational Analysis of Geodiamolide Analogues
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Synthesis and Biological Evaluation of Modified Miuraenamides
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Construction of β ‐Phenylalanine Derivatives through Pd‐Catalyzed, C(sp 2 )−H ( ortho ) Functionalization
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On the First Marine Stigmastane Sterols and Sterones Having a 24,25‐Double Bond. Isolation from the Sponge Stelletta sp. of Deep Coral Sea
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Antibiotics from Gliding Bacteria, LXX Chondramides A–D, New Cytostatic and Antifungal Cyclodepsipeptides from Chondromyces crocatus (Myxobacteria): Isolation and Structure Elucidation
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Marine Mollusk‐Derived Agents with Antiproliferative Activity as Promising Anticancer Agents to Overcome Chemotherapy Resistance
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Importance of aspartic acid side chain carboxylate‐arginine interaction in substrate selection of arginine 2,3‐aminomutase BlsG
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Separation and Isolation Techniques
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Using the Four-Cell C. elegans Embryo to Study Contractile Ring Dynamics During Cytokinesis
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Influencing the Actin Dynamics in Plant Cells by Jasplakinolide, Chondramides, Phalloidin, Cytochalasins, and Latrunculins
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Academic Chemistry and the Discovery of Bioactive Marine Natural Products
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Antitumor and Cytotoxic Compounds from Marine Organisms
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The Search for Antiparasitic Agents from Marine Animals
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Actin-Dynamics in Plant Cells: The Function of Actin-Perturbing Substances: Jasplakinolide, Chondramides, Phalloidin, Cytochalasins, and Latrunculins
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Destabilizing Agents
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Jasplakinolide: An Actin-Specific Reagent that Promotes Actin Polymerization
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Impact of Papua New Guinean Marine Biodiversity on the Discovery and Development of New Pharmaceuticals
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Drug molecules of marine origin
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Antitumor Effects of Sea Hare-Derived Compounds in Cancer
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Cytotoxic Cyclic Peptides from the Marine Sponges
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Entotheonella Bacteria as Source of Sponge-Derived Natural Products: Opportunities for Biotechnological Production
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Toxins Affecting Actin Filaments and Microtubules
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The Family Polyangiaceae
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Antimicrobial Peptides from Marine Organisms
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Myxobacteria as Producers of Secondary Metabolites
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Natural Product Peptides from Marine Organisms
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Drug Discovery: Nature’s Approach
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Bioactive Phenolics and Related Compounds
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Induction of apoptosis and CD10/neutral endopeptidase expression by jaspamide in HL-60 line cells
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Polarity establishment requires dynamic actin in fucoid zygotes
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Jasplakinolide reversibly disrupts actin filaments in suspension-cultured tobacco BY-2 cells
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Peptides with anticancer use or potential
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The five bromotryptophans
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Cytotoxic peptides from the marine sponge Cymbastela sp.
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Jaspiferals A ∼ G, new cytotoxic isomalabaricane-type nortriterpenoids from Okinawan marine sponge Jaspis stellifera
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Geodiamolides C to F, new cytotoxic cyclodepsipeptides from the marine sponge Pseudaxinyssa sp.
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Isolation and structure elucidation of perthamide B, a novel peptide from the sponge Theonella sp.
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Chemical Diversification of Natural Product Extracts
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Myxobacteria – Unique Microbial Secondary Metabolite Factories
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Pyrroles and their Benzo Derivatives: Applications
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Volume 2 References
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Synthesis, solution structure, and bioactivity of six new simplified analogues of the natural cyclodepsipeptide jaspamide
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Synthetic and pharmacological studies on new simplified analogues of the potent actin-targeting Jaspamide
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Myxobacteria versus sponge-derived alkaloids: The bengamide family identified as potent immune modulating agents by scrutiny of LC–MS/ELSD libraries
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Differential modulation of the antifungal activity of amphotericin B by natural and ent-cholesterol
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Synthesis and biological evaluation of new jasplakinolide (jaspamide) analogs
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Molecular and Biochemical Studies of Chondramide Formation—Highly Cytotoxic Natural Products from Chondromyces crocatus Cm c5
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Cytotoxic activities of hexane, ethyl acetate and butanol extracts of marine sponges from Mauritian Waters on human cancer cell lines
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Ethyl acetate extract of the Mauritian sponge Jaspis sp. induces cell arrest in human promyelocytic leukemia cells
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Electrospun polydioxanone/fucoidan blend nanofibers loaded with anti-cancer precipitate from Jaspis diastra and paclitaxel: Physico-chemical characterization and in-vitro screening
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Harnessing marine antimicrobial peptides for novel therapeutics: A deep dive into ocean-derived bioactives
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Force-dependent remodeling of cytoplasmic ZO-1 condensates contributes to cell-cell adhesion through enhancing tight junctions
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Myxobacteria: proficient producers of novel natural products with various biological activities—past and future biotechnological aspects with the focus on the genus Sorangium
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Mechanical and morphological response of confluent epithelial cell layers to reinforcement and dissolution of the F-actin cytoskeleton
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Cytoskeleton alterations induced by Geodia corticostylifera depsipeptides in breast cancer cells
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Seragamides A–F, new actin-targeting depsipeptides from the sponge Suberites japonicus Thiele
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Stereoselective synthesis of pachastrissamine (jaspine B)
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New jaspamide derivatives with antimicrofilament activity from the sponge Jaspis splendans
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Concise route to defined stereoisomers of the hydroxy acid of the chondramides
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Jaspamides H–L, new actin-targeting depsipeptides from the sponge Jaspis splendans
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Jaspamides M–P: new tryptophan modified jaspamide derivatives from the sponge Jaspis splendans
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Homochiral lithium amides for the asymmetric synthesis of β-amino acids
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Synthesis of novel N-protected β3-amino nitriles: study of their hydrolysis involving a nitrilase-catalyzed step
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The formal synthesis of 3-epi jaspine B using stereoselective intramolecular oxa-Michael addition
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Asymmetric synthesis of syn- and anti-α-deuterio-β3-phenylalanine derivatives
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2-Isopropylbenzimidazole and 2-methylbenzimidazole as bulky proton sources: Stereoselective protonation and application to the synthesis of γ- and δ-lactones
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Jasplakinolide, a cytotoxic natural product, induces actin polymerization and competitively inhibits the binding of phalloidin to F-actin.
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Syntheses of hapalosin analogs by solid-phase assembly of acyclic precursors
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Isopropenyl chlorocarbonate (IPCC)1 in amino acid and peptide chemistry: Esterification of N-protected amino acids; Application to the synthesis of the depsipeptide valinomycin
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Enantioselective total synthesis of doliculide, a potent cytotoxic cyclodepsipeptide of marine origin and structure-cytotoxicity relationships of synthetic doliculide congeners
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Hymenamides a and b, new proline-rich cyclic heptapeptides from the okinawan marine sponge hymeniacidon sp.
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Geodiamolides H and I, further cyclodepsipeptides from the marine sponge Geodia sp
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New hirsutane based sesquiterpenes from salt water cultures of a marine sponge-derived fungus and the terrestrial fungus Coriolus consors
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Malaysiatin, the first cyclic heptapeptide from a marine sponge
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Studies on cyclodepsipeptides - Part I : A stereoselective synthesis of C12 polyketide unit (C1–C8) present in Jaspamide and Geodiamolide A–F
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Hemiasterlin and geodiamolide TA; two new cytotoxic peptides from the marine sponge Hemiasterella minor (Kirkpatrick)
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Efficient syntheses of geodiamolide A and jaspamide, cytotoxic and antifungal cyclic depsipeptides of marine sponge origin
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Total syntheses of jaspamide (jasplakinolide) and geodiamolide A and B - 1. Stereoselective synthesis of (2,4,6,8)-8-hydroxy-2,4,6-trimethyl-4-nonenoicic acid1
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Total synthesis of the mixed peptide-polypropionate based cyclodepsipeptide (+)-geodiamolide b
inferred← citeshttps://doi.org/10.1016/s0040-4039(00)80794-7openalex-snapshot
Novel marine sponge derived amino acids 7. The fenestins
inferred← citeshttps://doi.org/10.1016/s0040-4039(00)82374-6openalex-snapshot
A practical synthesis of the peptide part of jaspamide (jasplakinolide), a cyclodepsipeptide from a marine sponge
inferred← citeshttps://doi.org/10.1016/s0040-4039(00)92064-1openalex-snapshot
Pseudoaxinellin, a cyclic heptapeptide isolated from the papua new guinea sponge pseudoaxinella massa
inferred← citeshttps://doi.org/10.1016/s0040-4039(00)92722-9openalex-snapshot
An ehantiospecific approach towards the C10 side-chain of bengamides
inferred← citeshttps://doi.org/10.1016/s0066-4103(08)60123-4openalex-snapshot
Recent Developments in Multiple Pulse NMR
inferred← citeshttps://doi.org/10.1016/s0099-9598(08)60105-4openalex-snapshot
Chapter 2 Marine Alkaloids II
inferred← citeshttps://doi.org/10.1016/s0301-4770(08)60401-7openalex-snapshot
Chapter 10 Bioactive Compounds from Marine Organisms and Cultivated Blue-Green Algae
inferred← citeshttps://doi.org/10.1016/s0957-4166(03)00218-0openalex-snapshot
Synthesis of Fmoc-protected (2S,3S)-2-hydroxy-3-amino acids from a furyl substituted chiral cyanohydrin
inferred← citeshttps://doi.org/10.1016/s0957-4166(97)00172-9openalex-snapshot
Asymmetric synthesis of the β-amino acid methyl ester derivative of onchidin: (2S,3S)-methyl-3-amino-2-methyl-7-octynoate and its enantiomer
inferred← citeshttps://doi.org/10.1016/s0960-9822(99)80478-3openalex-snapshot
Role of actin-filament disassembly in lamellipodium protrusion in motile cells revealed using the drug jasplakinolide
inferred← citeshttps://doi.org/10.1016/s1099-4831(05)61002-4openalex-snapshot
The Marine Bromotyrosine Derivatives
inferred← citeshttps://doi.org/10.1016/s1572-5995(00)80008-3openalex-snapshot
Structure-activity relationships of bioactive metabolites from some Indo-Pacific marine invertebrates
inferred← citeshttps://doi.org/10.1016/s1572-5995(00)80009-5openalex-snapshot
Biosynthesis of bioactive marine natural products
inferred← citeshttps://doi.org/10.1016/s1572-5995(02)80013-8openalex-snapshot
Secondary metabolites with antinematodal activity
inferred← citeshttps://doi.org/10.1016/s1572-5995(02)80027-8openalex-snapshot
The chemistry of lithistid sponge: A spectacular source of new metabolites
inferred← citeshttps://doi.org/10.1016/s1572-5995(05)80054-7openalex-snapshot
Bioactive natural products from southern African marine invertebrates
inferred← citeshttps://doi.org/10.1021/acs.chemrev.9b00063openalex-snapshot
Comprehensive Structure–Activity Relationship Studies of Macrocyclic Natural Products Enabled by Their Total Syntheses
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.5b00987openalex-snapshot
A Grand Challenge: Unbiased Phenotypic Function of Metabolites from Jaspis splendens against Parkinson’s Disease
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.5c00433openalex-snapshot
Jaspamide/Jasplakinolide Is Synthesized by Jaspinella (Tectomicrobia) Bacteria in Sponges
inferred← citeshttps://doi.org/10.1021/acs.orglett.3c03366openalex-snapshot
Reshaping the Substrate Binding Pocket of β-Amino Acid Dehydrogenase for the Synthesis of Aromatic β-Amino Acids
inferred← citeshttps://doi.org/10.1021/acsinfecdis.3c00067openalex-snapshot
Screen for New Antimicrobial Natural Products from the NCI Program for Natural Product Discovery Prefractionated Extract Library
inferred← citeshttps://doi.org/10.1021/ar100106nopenalex-snapshot
Chemically Engineered Extracts: Source of Bioactive Compounds
inferred← citeshttps://doi.org/10.1021/bi962840popenalex-snapshot
Bromocontryphan: Post-Translational Bromination of Tryptophan
inferred← citeshttps://doi.org/10.1021/co100073kopenalex-snapshot
Brominated Extracts As Source of Bioactive Compounds
inferred← citeshttps://doi.org/10.1021/ja010015copenalex-snapshot
Halipeptins A and B: Two Novel Potent Anti-inflammatory Cyclic Depsipeptides from the Vanuatu Marine Sponge Haliclona species
inferred← citeshttps://doi.org/10.1021/ja211708zopenalex-snapshot
Selective Chemical Imaging of Static Actin in Live Cells
inferred← citeshttps://doi.org/10.1021/ja4054509openalex-snapshot
Microsclerodermins from Terrestrial Myxobacteria: An Intriguing Biosynthesis Likely Connected to a Sponge Symbiont
inferred← citeshttps://doi.org/10.1021/ja9095126openalex-snapshot
Synthesis and Structure−Activity Correlation of Natural-Product Inspired Cyclodepsipeptides Stabilizing F-Actin
inferred← citeshttps://doi.org/10.1021/ja961314iopenalex-snapshot
Onchidin B: A New Cyclodepsipeptide from the Mollusc Onchidium sp.
inferred← citeshttps://doi.org/10.1021/jf0207880openalex-snapshot
Marine Natural Products as Prototype Agrochemical Agents
inferred← citeshttps://doi.org/10.1021/jf960746+openalex-snapshot
Marine Natural Products as Prototype Insecticidal Agents
inferred← citeshttps://doi.org/10.1021/jm000168vopenalex-snapshot
Inhibition of Protein Synthesis by Didemnins: Cell Potency and SAR
inferred← citeshttps://doi.org/10.1021/jm9013554openalex-snapshot
New Structures and Bioactivity Properties of Jasplakinolide (Jaspamide) Analogues from Marine Sponges
inferred← citeshttps://doi.org/10.1021/jo0344079openalex-snapshot
trans-Cyclopropyl β-Amino Acid Derivatives via Asymmetric Cyclopropanation Using a (Salen)Ru(II) Catalyst
inferred← citeshttps://doi.org/10.1021/jo3027643openalex-snapshot
Total Synthesis and Configurational Assignment of the Marine Natural Product Haliclamide
inferred← citeshttps://doi.org/10.1021/jo7018202openalex-snapshot
Stereoselective Synthesis of Quaternary Center Bearing Azetines and Their β-Amino Acid Derivatives
inferred← citeshttps://doi.org/10.1021/jo962217aopenalex-snapshot
Total Synthesis of Dolatrienoic Acid: A Subunit of Dolastatin 14
inferred← citeshttps://doi.org/10.1021/jo970036iopenalex-snapshot
Geographic Variation in the Tropical Marine Sponge Jaspis cf. johnstoni: An Unexpected Source of New Terpene-Benzenoids
inferred← citeshttps://doi.org/10.1021/np000478gopenalex-snapshot
New Cytotoxic Isomalabaricane Triterpenes from the Sponge Jaspis Species
inferred← citeshttps://doi.org/10.1021/np0106283openalex-snapshot
Structure and Absolute Stereochemistry of Hectochlorin, a Potent Stimulator of Actin Assembly
inferred← citeshttps://doi.org/10.1021/np049955bopenalex-snapshot
Synthesis, Conformational Analysis, and Cytotoxicity of New Analogues of the Natural Cyclodepsipeptide Jaspamide
inferred← citeshttps://doi.org/10.1021/np050293fopenalex-snapshot
Using Jasplakinolide to Turn on Pathways that Enable the Isolation of New Chaetoglobosins from Phomospis asparagi
inferred← citeshttps://doi.org/10.1021/np100721gopenalex-snapshot
Biostructural Features of Additional Jasplakinolide (Jaspamide) Analogues
inferred← citeshttps://doi.org/10.1021/np200714mopenalex-snapshot
Pipestelides A–C: Cyclodepsipeptides from the Pacific Marine SpongePipestela candelabra
inferred← citeshttps://doi.org/10.1021/np4003367openalex-snapshot
Gombamide A, a Cyclic Thiopeptide from the Sponge Clathria gombawuiensis
inferred← citeshttps://doi.org/10.1021/np500041xopenalex-snapshot
Scrutinizing the Scaffolds of Marine Biosynthetics from Different Source Organisms: Gram-Negative Cultured Bacterial Products Enter Center Stage
inferred← citeshttps://doi.org/10.1021/np700738kopenalex-snapshot
Antineoplastic Agents. 536. New Sources of Naturally Occurring Cancer Cell Growth Inhibitors from Marine Organisms, Terrestrial Plants, and Microorganisms,
inferred← citeshttps://doi.org/10.1021/np800817yopenalex-snapshot
A Selective Account of Effective Paradigms and Significant Outcomes in the Discovery of Inspirational Marine Natural Products
inferred← citeshttps://doi.org/10.1021/np900565aopenalex-snapshot
Assessing Pressurized Liquid Extraction for the High-Throughput Extraction of Marine-Sponge-Derived Natural Products
inferred← citeshttps://doi.org/10.1021/np970050qopenalex-snapshot
Bengamides and Related New Amino Acid Derivatives from the New Caledonian Marine Sponge Jaspis carteri
inferred← citeshttps://doi.org/10.1021/np9803225openalex-snapshot
New Jaspamide Derivatives from the Marine Sponge Jaspis splendans Collected in Vanuatu
inferred← citeshttps://doi.org/10.1021/np990155oopenalex-snapshot
New Geodiamolides from the Sponge Cymbastela sp. Collected in Papua New Guinea
inferred← citeshttps://doi.org/10.1021/np9902688openalex-snapshot
Cytotoxic Metabolites from an Australian Collection of the Sponge Jaspis Species
inferred← citeshttps://doi.org/10.1021/ol035476copenalex-snapshot
A New Cytotoxic and Tubulin-Interactive Milnamide Derivative from a Marine Sponge Cymbastela sp.
inferred← citeshttps://doi.org/10.1021/ol036446copenalex-snapshot
A Further Study of the Cytotoxic Constituents of a Milnamide-Producing Sponge
inferred← citeshttps://doi.org/10.1021/ol070855hopenalex-snapshot
Enantioselective Total Synthesis of (+)-Jasplakinolide
inferred← citeshttps://doi.org/10.1021/ol1001126openalex-snapshot
Diastereoselective Allylstannane Additions to (S)-5,6-Dihydro-2H-5-phenyloxazin-2-one. A Concise Synthesis of (S)-β-Methylisoleucine
inferred← citeshttps://doi.org/10.1021/ol5003797openalex-snapshot
Cyclic Carbo-Isosteric Depsipeptides and Peptides as a Novel Class of Peptidomimetics
inferred← citeshttps://doi.org/10.1023/a:1002405815493openalex-snapshot
Marine pharmacology
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