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Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata 1,2

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DFT Studies of Camptothecins Cytotoxicity II. Protonated Lactone Forms of Camptothecin
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9-aminocamptothecin by 72-hour continuous intravenous infusion is Inactive in the treatment of patients with 5-fluorouracil-refractory colorectal carcinoma
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Total Synthesis of Camptothecin and Related Natural Products by a Flexible Strategy
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inferred← citeshttps://doi.org/10.1002/anie.202112573openalex-snapshot
Maximizing Step‐Normalized Increases in Molecular Complexity: Formal [4+2+2+2] Photoinduced Cyclization Cascade to Access Polyheterocycles Possessing Privileged Substructures
inferred← citeshttps://doi.org/10.1002/anie.202423446openalex-snapshot
Chiral Nanofibers of Camptothecin Trigger Pyroptosis for Enhanced Immunotherapy
inferred← citeshttps://doi.org/10.1002/aoc.4210openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/asia.201403190openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/bmc.4944openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/btpr.3039openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/cbdv.201000307openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/cbdv.201100195openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/cbdv.201200311openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/cbdv.201600180openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/cem.2488openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/chem.201101389openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/chem.201200043openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/chem.201301200openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/chem.201303633openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/chem.202101074openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/cjoc.19840020211openalex-snapshot
Mass spectrometric study of camptothecin and related compounds
inferred← citeshttps://doi.org/10.1002/cjoc.200690105openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/cjoc.201800358openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/cmdc.200700138openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/cmdc.201000369openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/cmdc.201100206openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/cmdc.201100456openalex-snapshot
RAFT‐Derived Polymer–Drug Conjugates: Poly(hydroxypropyl methacrylamide) (HPMA)–7‐Ethyl‐10‐hydroxycamptothecin (SN‐38) Conjugates
inferred← citeshttps://doi.org/10.1002/cmdc.201200322openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/cmdc.201600391openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/cmdc.201900633openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/cmdc.202000753openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/cmdc.202200032openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/cphc.201300461openalex-snapshot
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Catalytic Enantioselective Aldol Additions to Ketones
inferred← citeshttps://doi.org/10.1002/ejoc.201000796openalex-snapshot
Synthesis and Characterization of a Multi Ring‐Fused 2‐Pyridone‐Based Fluorescent Scaffold
inferred← citeshttps://doi.org/10.1002/ejoc.201501401openalex-snapshot
Incorporation of the Constrained Peptidomimetic, 5‐Methylpyridin‐2‐one into Peptide Vinyl Sulfones and Peptide Epoxy Ketones is Detrimental for Proteasome Inhibition
inferred← citeshttps://doi.org/10.1002/ejoc.201900001openalex-snapshot
Recent Advances in the A 3 Coupling Reactions and their Applications
inferred← citeshttps://doi.org/10.1002/ejoc.202000365openalex-snapshot
Superbase‐Mediated Indirect Friedländer Reaction: A Transition Metal‐Free Oxidative Annulation toward Functionalized Quinolines
inferred← citeshttps://doi.org/10.1002/ejoc.202001048openalex-snapshot
Cyclative MCRs of Azines and Azinium Salts
inferred← citeshttps://doi.org/10.1002/ejoc.202500167openalex-snapshot
Recent Advances of Enaminones in Multi‐component Reactions: A Brief Review
inferred← citeshttps://doi.org/10.1002/hep.20174openalex-snapshot
Topoisomerase inhibitor camptothecin sensitizes mouse hepatocytes in vitro and in vivo to TNF-mediated apoptosis
inferred← citeshttps://doi.org/10.1002/hlca.19740570604openalex-snapshot
Synthese von 1,6‐Trimethylen‐3‐methoxycarbonyl‐4‐methyl‐2‐pyridon
inferred← citeshttps://doi.org/10.1002/hlca.200890218openalex-snapshot
Synthetic Studies on Camptothecins. Part 1
inferred← citeshttps://doi.org/10.1002/ijc.10434openalex-snapshot
Novel camptothecin derivative BNP1350 in experimental human ovarian cancer: Determination of efficacy and possible mechanisms of resistance
inferred← citeshttps://doi.org/10.1002/ijc.20216openalex-snapshot
Novel camptothecin analogues that circumvent ABCG2‐associated drug resistance in human tumor cells
inferred← citeshttps://doi.org/10.1002/ijc.2910500420openalex-snapshot
Effects of CPT‐11 in combination with other anti‐cancer agents in culture
inferred← citeshttps://doi.org/10.1002/ijc.2910530526openalex-snapshot
Camptothecin derivatives induce regression of human ovarian carcinomas grown in nude mice and distinguish between non‐tumorigenic and tumorigenic cells in vitro
inferred← citeshttps://doi.org/10.1002/ijc.2910620519openalex-snapshot
Local delivery of the topoisomerase I inhibitor camptothecin sodium prolongs survival in the rat intracranial 9L gliosarcoma model
inferred← citeshttps://doi.org/10.1002/j.1552-4604.1990.tb01873.xopenalex-snapshot
New Natural Products in Cancer Chemotherapy
inferred← citeshttps://doi.org/10.1002/jbm.a.31445openalex-snapshot
Diffusion of camptothecin immobilized with cationic surfactant into agarose hydrogel containing anionic carrageenan
inferred← citeshttps://doi.org/10.1002/jbm.a.31452openalex-snapshot
A novel polyrotaxane‐based intracellular delivery system for camptothecin: In vitro feasibility evaluation
inferred← citeshttps://doi.org/10.1002/jccs.199300001openalex-snapshot
The Camptothecins: A Reborn Family of Antitumor Agents
inferred← citeshttps://doi.org/10.1002/jccs.199400050openalex-snapshot
Antineoplastic Alkaloids From Chinese Medicinal Plants and Their Analogs
inferred← citeshttps://doi.org/10.1002/jccs.201300631openalex-snapshot
Supercritical Fluid Extraction of Camptothecin from Nothapodytes Foetida
inferred← citeshttps://doi.org/10.1002/jccs.201700314openalex-snapshot
Molecular docking study and structure‐based design of novel camptothecin analogues used as topoisomerase I inhibitor
inferred← citeshttps://doi.org/10.1002/jcla.20190openalex-snapshot
Determination of hydroxycamptothecinum by flow injection analysis with chemiluminescence detection
inferred← citeshttps://doi.org/10.1002/jhet.14openalex-snapshot
The reaction of (chlorocarbonyl)phenyl ketene with enaminones: A novel synthesis of some 5‐acyl‐4‐hydroxy‐2‐(1H)‐pyridinones and 7‐hydroxy‐5‐oxo‐1,4‐diazepin derivative
inferred← citeshttps://doi.org/10.1002/jhet.4654openalex-snapshot
Synthesis of 5‐spirocycle camptothecin using ring‐closing metathesis strategy
inferred← citeshttps://doi.org/10.1002/jhet.5570080304openalex-snapshot
Total synthesis of camptotheein. I. Synthesis of ethyl 8‐(α‐chlorobutyryloxymethyl)‐7,9‐dioxo‐7,8,9,11 ‐tetrahydroindolizino[ 1,2‐a]quinoline‐8‐carboxylate and related tetracyclic compounds
inferred← citeshttps://doi.org/10.1002/jhet.5570090247openalex-snapshot
Preparation of 1,2‐dihydro‐3‐oxo‐3H‐pyrrolo[3,4‐b]quinoline derivatives from 2,3‐dioxopyrrolidines
inferred← citeshttps://doi.org/10.1002/jhet.5570100117openalex-snapshot
Synthesis of a potential camptothecin intermediate
inferred← citeshttps://doi.org/10.1002/jhet.5570100505openalex-snapshot
Synthetic studies leading to DE‐ring analogs of camptothecin
inferred← citeshttps://doi.org/10.1002/jhet.5570300311openalex-snapshot
Synthesis of C‐nor‐4,6‐secocamptothecin and related compounds
inferred← citeshttps://doi.org/10.1002/jhet.5570400105openalex-snapshot
Studies on pyrrolidinones. Synthesis of new α‐pyridones derivatives
inferred← citeshttps://doi.org/10.1002/jhet.5570450209openalex-snapshot
Simple and efficient one‐pot synthesis of 3,4‐dihydro‐2‐pyridones via solid‐supported Bi(III)nitrate catalyzed double michael addition‐azaannulation
inferred← citeshttps://doi.org/10.1002/jhet.5570450548openalex-snapshot
Synthesis of condensed pyridones by using a new ring switching reaction
inferred← citeshttps://doi.org/10.1002/jhet.590openalex-snapshot
Synthesis of 5‐aryl and 5‐amidocamptothecins
inferred← citeshttps://doi.org/10.1002/jlac.19717450105openalex-snapshot
Reaktionen an Indolderivaten, XIII. Chinolon‐Derivate durch Autoxydation
inferred← citeshttps://doi.org/10.1002/jlcr.1245openalex-snapshot
Syntheses of isotopomers of SK&F‐S‐104864, topotecan HCl
inferred← citeshttps://doi.org/10.1002/jlcr.1690openalex-snapshot
Synthesis and biological evaluation of 99mTc(CO)3(IDA‐CPT) for tumor imaging
inferred← citeshttps://doi.org/10.1002/jlcr.2580180306openalex-snapshot
The preparation of tritium and deuterium‐labelled camptothecin
inferred← citeshttps://doi.org/10.1002/jlcr.2580281106openalex-snapshot
Synthesis of tritiated (S)‐10‐bromoacetamidomethylcamptothecin
inferred← citeshttps://doi.org/10.1002/jlcr.2580330907openalex-snapshot
Synthesis of position‐specific tritium‐labeled 20(S)‐camptothecin, 9‐amino‐20(S)‐camptothecin, and 10,11‐methylenedioxy‐20(S)‐camptothecin
inferred← citeshttps://doi.org/10.1002/jps.1028openalex-snapshot
Hepatic extraction, metabolism, and biliary excretion of irinotecan in the isolated perfused rat liver
inferred← citeshttps://doi.org/10.1002/jps.2600591118openalex-snapshot
Common Receptor-Complement Feature Among Some Antileukemic Compounds
inferred← citeshttps://doi.org/10.1002/jps.2600630203openalex-snapshot
Camptothecin
inferred← citeshttps://doi.org/10.1002/jps.2600630335openalex-snapshot
Modern Approaches for Selecting Biologically Active Plants I: CNS Depressants
inferred← citeshttps://doi.org/10.1002/jps.2600630427openalex-snapshot
Tumor Inhibitors I: Preliminary Investigation of Antitumor Activity of Sarracenia flava
inferred← citeshttps://doi.org/10.1002/jps.2600761129openalex-snapshot
Poster session M-1: Organic reactions and syntheses Thursday, December 3, 11:00 a.m. – 2:00 p.m. Kamehameha foyer, Surfrider posters M 03-Y-01 through M 03-Y-39
inferred← citeshttps://doi.org/10.1002/jps.2600830710openalex-snapshot
Stabilization of Topotecan in Low pH Liposomes Composed of Distearoylphosphatidylcholine
inferred← citeshttps://doi.org/10.1002/jrs.4761openalex-snapshot
Contribution and limits of a non‐intrusive Raman spectroscopic method compared with HPLC for routine application to pre‐delivery analytical control of two major camptothecin analogs: irinotecan and topotecan
inferred← citeshttps://doi.org/10.1002/jso.2930540404openalex-snapshot
Growth inhibition of human gastrointestinal cancer xenograft lines by treatment with CPT‐11 and VP‐16
inferred← citeshttps://doi.org/10.1002/jso.2930590209openalex-snapshot
Establishment and characterization of human gastric and colonic xenograft lines resistant to CPT‐11 (A new derivative of camptothecin)
inferred← citeshttps://doi.org/10.1002/jssc.201900347openalex-snapshot
Pharmacokinetics of 10‐hydroxycamptothecin–tetrandrine liposome complexes in rat by a simple and sensitive ultra‐high performance liquid chromatography with tandem mass spectrometry
inferred← citeshttps://doi.org/10.1002/mabi.201300414openalex-snapshot
Acidity‐ P romoted Cellular Uptake and Drug Release Mediated by Amine‐ F unctionalized Block Polycarbonates Prepared via One‐ S hot Ring‐ O pening Copolymerization
inferred← citeshttps://doi.org/10.1002/mabi.201500094openalex-snapshot
Shell Cross‐Linked Polymeric Micelles as Camptothecin Nanocarriers for Anti‐HCV Therapy
inferred← citeshttps://doi.org/10.1002/mabi.201600299openalex-snapshot
Achieving High Drug Loading and Sustained Release of Hydrophobic Drugs in Hydrogels through In Situ Crystallization
inferred← citeshttps://doi.org/10.1002/marc.202000260openalex-snapshot
Polymerization‐Induced Self‐Assembly to Produce Prodrug Nanoparticles with Reduction‐Responsive Camptothecin Release and pH‐Responsive Charge‐Reversible Property
inferred← citeshttps://doi.org/10.1002/med.21342openalex-snapshot
Perspectives on Biologically Active Camptothecin Derivatives
inferred← citeshttps://doi.org/10.1002/med.21377openalex-snapshot
Strategies for the Optimization of Natural Leads to Anticancer Drugs or Drug Candidates
inferred← citeshttps://doi.org/10.1002/med.21466openalex-snapshot
Biologically active quinoline and quinazoline alkaloids part I
inferred← citeshttps://doi.org/10.1002/med.21546openalex-snapshot
Topoisomerase 1B poisons: Over a half‐century of drug leads, clinical candidates, and serendipitous discoveries
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